Critical Care Reviews Podcast
Rob Mac Sweeney
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The Critical Care Reviews Podcast discusses the biggest critical care trials, either planned or in progress, with their chief investigators. It's hosted by Rob Mac Sweeney, an intensivist in Belfast, Northern Ireland. The podcast also releases audio versions of presentations from the Critical Care Reviews Meetings and ad hoc livestreams.
Epizody
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GASTRIC-PICU 29.09.2026 1h 29minLyvonne Tume (Liverpool) and David Harrison (London) present the results of the GASTRIC-PICU trial at the Critical Care Reviews Meeting 2026 in Titanic Belfast. GASTRIC-PICU investigates the effect of gastric residual volume monitoring in critically ill children receiving mechanical ventilation. Srinivas Murthy (Vancouver) delivers an editorial. Marion Campbell (Aberdeen), John Dorling (Leeds) and Christopher Seymour (Pittsburgh) contribute to a panel discussion. The session is chaired by Kartryn Puxty (Glasgow). GASTRIC-PICU was simultaneously published in JAMA. -
John Hinds Lecture CCR26 29.09.2026 50minProf Deborah Cook (Hamilton, Canada) presents the 2026 John Hinds Lecture, titled "Purpose and Passion". -
BIHCA Trial Presentation 29.09.2026 1h 31minAsger Grenfeldt (Aarhus) and Lars Wiuff Andersen (Aarhus) present the results of the BIHCA trial at the Critical Care Reviews Meeting 2026 in Titanic Belfast. BIHCA investigates the efficacy of sodium bicarbonate in cardiac arrest. Ary Serpa Neto (Melbourne) gives an independent editorial. Aryelly Rodriguez (Edinburgh), Kathy Rowan (London) and Angela Jerath (Toronto) contribute to a panel discussion. The session is chaired by Peter McGuigan (Belfast). BIHCA was simultaneously published in JAMA. -
ARISE-FLUIDS Trial Presentation 29.09.2026 1h 32minStephen Macdonald (Perth), Belinda Howe (Melbourne) and Sandra Peake (Adelaide) present the results of the ARISE FLUIDS trial at the Critical Care Reviews Meeting 2026 in Titanic Belfast. ARISE FLUIDS compares two septic shock resuscitation strategies - restricted fluids and early vasopressors or a larger initial intravenous fluid volume and later vasopressors. Tine Sylvest Meyhoff (Copenhagen) delivers an independent editorial. David Harrison (London), Marlies Ostermann (London) and Israel Maia (Sao Paulo) contribute to a panel discussion. The session is chaired by Darren Taichman (Philadelphia). ARISE FLUIDS was simultaneosuly published in the New England Journal of Medicine. -
ACCOMPLISH Trial Presentation 29.09.2026 1h 2minKristin Mayes (Pittsburgh) and Sachin Yende (Pittsburgh) present the results of the ACCOMPLISH trial at the Critical Care Reviews Meeting 2026 in Titanic Belfast. ACCOMPLISH investigates the effects of remote patient monitoring for preventing hospital readmission following infection and sepsis. Jo McPeake (Cambridge) delivers an independent editorial. Victoria Cornelius (London), Brenda O'Neill (Belfast) and Adriano Jose Pereira (Sao Paulo) contribute to a panel discussion. The session is chaired by Carol Hodgson (Melbourne). ACCOMPLISH was simultaneously published in JAMA Network Open. -
ANDROMEDA-SHOCK 2 Trial 24.09.2026 29minRob Mac Sweeney discusses the ANDROMEDA-SHOCK 2 trial with Prof Jan Bakker, one of the leads for this major international randomised controlled trial investigating peripheral perfusion guided resuscitation in septic shock -
Tigris Trial 30.04.2026 41minRob Mac Sweeney discusses the Tigris Trial with chief investigator John Kellum. Tigris investigated the efficacy of polymyxin B haemoadsorption in endotoxic septic shock. It was published in Lancet Respiratory Medicine in March, 2026. -
ACIOS Study 21.03.2025 27minRob Mac Sweeney discusses the ACIOS study with Tim Baker, the study lead. ACIOS is a point prevalence study describing the burden of critical illness in Africa. It was published in the Lancet in March, 2025. -
IVIO Trial 13.11.2024 28minRob Mac Sweeney discusses the IVIO trial with investigators Lars Wiuff Andersen and Mikael Fink Valentine from Aarhus, Denmark. The IVIO trial compared intraosseous with intravenous vascular access in adult patients suffering an out-of-hospital cardiac arrest. It was presented at the 2024 European Resuscitation Council congress in Athens and simultaneously published in the New England Journal of Medicine. -
PARAMEDIC 3 Trial 12.11.2024 39minRob Mac Sweeney discusses the PARAMEDIC 3 trial with it's investigators Keith Couple and Ranjit Lall from the University of Warwick, England. PARAMEDIC 3 compared intravenous with intraosseous vascular access in adult patients suffering cardiac arrest and requiring drug administration during ongoing resuscitation. It was presented at the European Resuscitation Council meeting in Athens on October 31st and simultaneously published in the New England Journal of Medicine. -
B-FREE Trial 07.04.2024 40minRob Mac Sweeney chats with Jessica Spence about the B-FREE trial, investigating benzodiazepine-free anaesthesia for the prevention of delirium in cardiac surgery -
Beyond Platform Trials Panel Discussion 13.03.2024 1h 4minBala Venkatesh (Brisbane) hosts a panel discussion entitled "Beyond Platform Trials" at the Critical Care Reviews Meeting 2023. The panellists include Bronagh Blackwood (Belfast), Susan Rowell (Chicago), Fernando Zampieri (Edmonton), Marion Campbell (Aberdeen), David Harrison (London), Roger Lewis (Los Angeles), Derek Angus (Pittsburgh) & Kathy Rowan (London). -
Causality Panel Discussion 13.03.2024 1hKathy Rowan (London) hosts a fascinating panel discussion on causality at the Critical Care Reviews Meeting 2023. The panellists include Bronwen Connolly (Belfast), Ewan Goligher (Toronto), Flavia Machado (Sao Paulo), Kath Maitland (Kalifi), John Norrie (Edinburgh), Victoria Cornelius (London), Andrew Althouse (Pittsburgh) and Chris Seymour (Pittsburgh). -
REMAP-CAP Trial Long Term Outcomes 13.03.2024 47minDr Lisa Higgins (Melbourne) presents the long term outcomes of the REMAP-CAP domains at the Critical Care Reviews Meeting 2023. Prof Howard Bauchner (Boston) delivers an editorial. Prof Christopher Seymour (Pittsburgh) chairs the session. -
AID-ICU Trial 13.03.2024 38minNina Christine Andersen-Ranberg presents the AID-ICU trial, investigating haloperidol for the management of delirium in the ICU. Danny McAuley delivers an editorial. Anders Perner joins the discussion and the session is chaired by Paul Mouncey. -
John Hinds Lecture 2023 13.03.2024 28minProf Flavia Machado (Sao Paulo) delivers the John Hinds Lecture at the Critical Care Reviews Meeting 2023, describing the story of BRICNET, the Brazilian Critical Care Trials Group. The session commences with Dr Chris Nutt remembering our friend, Dr John Hinds. -
PROCOAG Trial 05.02.2024 39minYou're listening to the audio version of the PROCOAG trial presentation from the Critical Care Reviews Meeting 2023. The PROCOAG trial investigated the efficacy and safety of early administration of 4-factor prothrombin complex concentrate in trauma patients at risk of massive transfusion. The trial is presented by Pierre Bouzat from Grenoble. Susan Rowell from Chicago, delivers the editorial. The session is chaired by Chris Seymour (Pittsburgh). PROCOAG was published in JAMA in March 2023. -
TEAM Trial 05.02.2024 43minYou're listening to the audio version of the TEAM trial presentation from the Critical Care Reviews Meeting 2023. The TEAM trial investigated early active mobilisation in critically ill mechanically ventilated patients. The trial is presented by Carol Hodgson from Melbourne. Darren Taichman from Philadelphia, delivers the editorial. The session is chaired by Paul Mouncey (Pittsburgh). -
PILOT Trial 26.01.2024 46minMatthew Semler (Nashville, USA) presents the PILOT trial at the Critical care Reviews Meeting 2023, in Titanic Belfast. The PILOT trial compared low, intermediate and high oxygenation targets in critically ill mechanically ventilated patients. Kath Maitland from Kigali, Kenya, delivers an independent editorial. The session is chaired by Chris Seymour from Pittsburgh, USA. PILOT was published in the New England Journal of Medicine on November 10th, 2022. -
REMAP-CAP / LOVIT-COVID Vitamin C Trial 16.01.2024 52minDr Francois Lamontagne joins Rob Mac Sweeney to discuss the harmonised REMAP-CAP / LOVIT-COVID vitamin C trial. The trial was presented at the European Society of Intensive Care Medicine annual congress and simultaneously published in the New England Journal of Medicine.
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