Talking Biotech with Dr. Kevin Folta

Dr. Neil Stewart-Radiation Sensing Potatoes 16.06.2026 24min

Plants can't get up and walk away from stress or predators, so they've evolved sensitive systems to sense and in some cases anticipate changes in their environment. Now, there's sensors to light, to humidity, to touch, to gravity, to dozens of other prevailing factors that push information from the external environment into the nucleus, shaping gene expression and adapting. To that change. Now, the fun part about this in today's era of synthetic biology is that the plant sensor and response systems are basically a toolbox. They're a template for synthetic innovation, as we can use their sense and response systems to work for us. Now, a number of plant-based sensors have been developed over the years. We're speaking with Dr. Neil Stewart. He's the professor in the plant department of plant sciences at the University of Tennessee and also the co-director of agricultural synthetic biology. So you've invented a potato plant that senses radiation to let us know it's there. So why do we need a plant radiation sensor?

Milk Proteins without the Dairy - Adam Tarshis and Dr. Cory Tobin 09.06.2026 47min

The proteins that give cheese its unique elasticity and eating quality are challenging to create outside of the cow. However, the team at Mozza has developed a method to generate the milk proteins in soybeans, exploiting the potential massive scale of field crop production, and providing a dairy-free source of these important proteins. Today's podcast interviews Adam Tarshis and Dr. Cory Tobin from Mozza.

New Technology in Severe Burn Care - Dr. Katie Bush 01.06.2026 28min

Severe burns require specialized care and long healing times at great expense. This week's Talking Biotech podcast explores the latest advancements in burn treatment technology with Dr. Katie Bush from Aveda Medical. Discover how innovative cell therapies and regenerative techniques are transforming wound healing, reducing hospital stays, and improving cosmetic outcomes.00:00Introduction to Burn Care Innovations02:13Understanding Burn Physiology05:18Challenges in Traditional Burn Treatments08:04Revolutionizing Burn Treatment with Resell Technology11:06Mechanisms of Resell Technology14:04Operational Impact on Burn Centers16:42Exploring Additional Applications of Resell19:37Future Directions in Burn Care Technology

Molecular Residue Cancer Detection - Dr. Nate Montgomery 25.05.2026 37min

This episode explores the latest advancements in personalized DNA and RNA technologies for early cancer detection, diagnostics, and treatment monitoring. New technologies identify molecular signatures of tumors that help predict onset and re-occurrence of disease. Dr. Nathan Montgomery from Neo Genomics Laboratories discusses how molecular residual disease testing, liquid biopsies, and genomic sequencing are transforming oncology care.

Strategies in Combating Chronic Kidney Disease - Dr. Salvatore Viscomi 17.05.2026 37min

Chronic kidney disease (CKD) is a pressing health issue that affects over a billion people worldwide, yet it often goes unnoticed until it's too late. In this post, we'll explore insights from Dr. Salvatore Viscomi, the CEO and founder of Carna Health, who sheds light on the alarming prevalence of CKD, its underlying causes, and the innovative solutions being implemented to address this global health crisis.Resources & Links:Carna Health Official WebsiteLinkedIn Profile of Salvadore ViscomiSiemens Biomarker Testing SolutionsFDA Clearances for Point of Care Testing DevicesConnect with Dr. Salvator Viscome:LinkedInTwitter

AI and the Future of Healthcare -- Dr. Emilia Javorsky 08.05.2026 39min

This week's Talking Biotech Podcast examines the realistic potential of AI in cancer research and healthcare, emphasizing data quality, individualization, and system reform. Guest: Dr. Emilia Javorsky, Future of Life Institute. Future of Life InstituteAI and Cancer: A New Frontier

The First Environmental GE Organism Release - almost! Dr. Steven Lindow 28.04.2026 25min

This episode explores the pioneering work on ice minus bacteria and their role in frost damage prevention in plants. Dr. Steven Lindow shares insights into early biotech innovations, regulatory challenges, and the potential for modern applications of this technology.

New Frontiers in Therapeutic Peptides - Dr. Karsten Eastman 16.04.2026 33min

In this episode of the Talking Biotech podcast, Dr. Karsten Eastman discusses the significance of peptides in biology and their therapeutic potential. He explains the roles of peptides, particularly GLP-1 therapeutics, and the challenges associated with their stability and bioavailability. The conversation delves into nature's strategies for enhancing peptide stability and how Sathera Therapeutics is innovating in this space to create more effective peptide-based therapies. The discussion also touches on the business model of Sathera and its focus on rare cancers and anti-inflammatory treatments.

Genetic Variation in Vegetative Propagation - Dr. Danelle Seymour 01.04.2026 28min

In this episode of the Talking Biotech podcast, Dr. Danelle Seymour discusses the genetic anomoliies observed in the vegetative propagation of tree crops, particularly citrus. The conversation delves into the importance of preserving genetic material through grafting, the challenges of genetic variation in vegetatively propagated plants, and the role of mutations in these processes. Dr. Seymour shares insights from her research on the historic Washington Naval orange tree and the implications of somatic mutations for breeding and disease resistance in citrus.

Conditionally Active Therapeutics - Dr. Neela Patel, Dr. Diane Hollenbaugh 27.02.2026 46min

In this episode of the Talking Biotech podcast, Dr. Kevin Folta speaks with Dr. Neela Patel and Dr. Diane Hollenbaugh from Bonum Therapeutics about the emerging field of conditionally active biologics. They discuss the challenges of current therapies, the innovative mechanisms behind their drug development, and the potential of immuno-oncology to revolutionize cancer treatment. The conversation also covers the market landscape, the origin story of Bonum, and the future directions for their pipeline, emphasizing the importance of targeted therapies in improving patient outcomes.

A Plasmid-Based Cancer Therapy - Dr. Alexander Schneider 17.02.2026 44min

In this episode of the Talking Biotech podcast, host Dr. Kevin Folta engages with Dr. Alex Schneider, CEO and founder of CureLab, to discuss innovative approaches to cancer treatment, particularly focusing on the challenges posed by refractory cancers such as triple-negative breast cancer and platinum-resistant ovarian cancer. Dr. Schneider emphasizes the evolution of cancer therapies from traditional chemotherapy to more sophisticated immunotherapies, highlighting the importance of understanding immune responses in combating cancer. He introduces Elanogen, a plasmid-based therapy designed to enhance immune presentation and combat chronic inflammation, which can hinder the effectiveness of conventional treatments like gemcitabine.The conversation delves into the mechanisms of Elanogen, explaining how it targets the P62 protein, which is overproduced in cancer cells, making them vulnerable to immune attacks. Dr. Schneider shares insights from clinical trials, noting the promising results of combining Elanogen with standard chemotherapy, and discusses future applications of this therapy in various cancers and even non-cancerous diseases associated with chronic inflammation. The episode concludes with a call for intellectual humility in science, as both hosts reflect on the evolving nature of cancer research and the potential for new discoveries in the field.

Biotech in Beauty Products - Nicholas Brideau 02.02.2026 1t 10min

This conversation explores the intersection of biotechnology and the beauty industry, highlighting how biotech is revolutionizing the production of cosmetic ingredients. The discussion covers the slow pace of innovation in beauty, the debate between natural and synthetic ingredients, and the role of AI in discovering new active compounds. The conversation also delves into specific examples like carmine production, the business model of Debut Biotech, and the regulatory challenges faced in bringing new products to market.

Molecular Biology Giants that Left Us In 2025 24.01.2026 1t 10min

2025 saw some of the giants in molecular biology leave us. Those that made seminal discoveries in DNA science to those that put it to work in describing the underpinnings of life left an indelible mark on history, and it is fitting that we commemorate their discoveries and contributions.

TB Throwback- Correcting the Veritasium Episode on Glyphosate 27.12.2025 1t 11min

This is a throwback to episode 484, a very important correction of their episode on glyphosate. With so much controversy around this compound it is critical to keep the information correct and consistent with a 50 year body of evidence when discussing risk and benefit. Veritassium made some mistakes, so here they are corrected so that you can participate effectively in these discussions.

TB Throwback: Gliblastoma and Cindy's Gift 20.12.2025 1t 4min

This episode originally aired on December 18, 2021. Cindy Graham was diagnosed with glioblastoma in her late 40s. She fought the disease, and ultimately donated her tissues to research to study the nature of glioblastoma and identify potential vulnerabilities that could underlie a cure. This episode first features Dr. Shiela Singh, glioblastoma expert who has performed analysis of Cindy's cells in search of a cure. The second part is an interview with her husband, Dr. Thomas Graham. He speaks of the power of her gift, Cindy's legacy, and the hope that cures may come because of her contribution. The fund supports glioblastoma research and student scholarships to enhance the best research in search of a cure. You can support the fund at www.cindysgift.com

TB Throwback: Dr. Avindra Nath and HERV-based Diseases 13.12.2025 50min

In today's throwback to 2022, Dr. Avindra Nath of the NIH reviews research efforts in proteins expressed from human endogenous retroviruses. It is a fascinating discussion of how genome relics may be contributing to insidious human disease.

482 Dr. Maxine Thompson, Episode 117, Jan 18, 2015 06.12.2025 37min

This throwback episode to 2018 is an interview with plant breeding pioneer Dr. Maxine Thompson.

A Biotech Probiotic to Enhance Fiber - Dr. Zack Abbott 02.11.2025 35min

In this episode of the Talking Biotech podcast, Dr. Kevin Folta and Dr. Zack Abbott discuss the critical role of dietary fiber in human health, the alarming statistics regarding fiber deficiency in the population, and the innovative solutions being developed by Zbiotics to address this issue. They delve into the science behind genetically engineered probiotics that can convert sugars into fiber, enhancing gut health and microbiome diversity. The conversation also touches on future possibilities for probiotic technology and its potential to solve modern health challenges.

Peer Review and Rigor in Controversial Science - Cam English, Dr. Liza Lockwood 19.10.2025 55min

This cross-platform podcast is shared on Science Facts and Fallacies as well as Talking Biotech. Cameron English, Dr. Liza Lockwood and Dr. Kevin Folta discuss the comments made during a rant on the Science Facts and Fallacies podcast concerning the rigor of peer review and alledged lack of self policing in academic publishing. They discuss several papers in the recent public eye, with an emphasis on the process, the media response, and the nuance that is used in academic publishing, review and editorial oversight.

Everyone Else is Lying to You - Pandemic Disinformation - Dr. Jonathan Howard 11.10.2025 49min

In this episode of the Talking Biotech podcast, Dr. Jonathan Howard discusses his experiences during the COVID-19 pandemic, the rise of disinformation, and the anti-vaccine movement. He reflects on his role as a physician at Bellevue Hospital, the impact of misinformation on public health, and the key players who have influenced the narrative surrounding vaccines and COVID-19. Dr. Howard emphasizes the need for the medical community to stand against misinformation and the importance of engaging in public discourse to restore trust in science and public health institutions.