Two Onc Docs
Sam and Karine
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Two Onc Docs is a podcast created by Sam and Karine, two board-certified hematologists and oncologists who graduated from their fellowships in 2021. The podcast offers short board review episodes designed for busy medical trainees, covering topics in hematology and oncology. It serves as a supplementary resource to other established study materials, intended for healthcare providers.
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Breast Cancer Screening, Prevention & Intro 2026 UPDATE 05.10.2026 17Min.We are providing 2026 update for our breast cancer episodes, today we cover an introduction on breast cancer screening, prevention. -
ctDNA & MRD: Current Applications, Limitations & What’s Next 28.09.2026 19Min.This week’s episode we are very excited to welcome back our special guest Dr. Hatim Husain, MD, a medical oncologist and physician-scientist at UC San Diego Moores Cancer Center, whose clinical and research expertise focuses on lung cancer and precision oncology. We further cover the topic of ctDNA, uses, limitations, and future directions. -
ctDNA, Liquid Biopsies, Methylation, NGS: What Does It All Mean? 21.09.2026 27Min.This week’s episode we are very excited to welcome a special guest Dr. Hatim Husain, MD, a medical oncologist and physician-scientist at UC San Diego Moores Cancer Center, whose clinical and research expertise focuses on lung cancer and precision oncology. We cover the topic of liquid biopsies, ctDNA, NGS panels definitions & current uses. -
Metastatic Non-Small Cell Lung Cancer 2026 UPDATE 14.09.2026 13Min.This week's episode focuses on metastatic non-small cell lung cancer - the quickly growing and changing systemic therapy landscape, including traditional chemotherapy, immunotherapy, and targeted agents. Since our last recording the number of FDA-approved targeted drugs has significantly expanded. -
Non-Small Cell Lung Cancer 2026 UPDATE 31.08.2026 13Min.This week's episode focuses on early-stage and locally advanced non-small cell lung cancer - staging, pathology, local and systemic therapy. Before we start, the usual caveat: the treatment landscape of NSCLC is changing FAST, which is exciting, but know that the boards run a few years behind. The big shifts since our last episode are the move to 9th-edition TNM staging and the arrival of four different perioperative chemo+immunotherapy regimens. Shout out to Dr. Bharathi Muthusamy for review... -
Myelodysplastic Syndrome (MDS) 2026 UPDATE 24.08.2026 10Min.Today’s episode is focusing on what you need to know regarding myelodysplastic syndrome (MDS). This will include the high yield facts on risk factors, diagnostic work-up, staging and treatment of MDS, we were overdue do this this topic, last done in 2022. -
Iron Overload 2026 UPDATE 17.08.2026 22Min.This week’s episode will be focusing on syndromes of iron overload. We will go over all important details on hemochromatosis and other related diseases. We last covered this topic in 2023. -
How to Approach a New Malignancy 101 03.08.2026 14Min.This week’s episode will be focusing on how to approach a newly diagnosed malignancy, biopsy, staging, patient considerations ect. -
Tips for Heme/Onc Fellowship 2026 28.07.2026 17Min.This week’s episode will be focusing on how to transition well into heme/onc fellowship including differences from residency, tips for surviving, wellness, resources & more. -
DLBCL 2026 UPDATE 20.07.2026 12Min.This week’s episode will be focusing on Diffuse Large B-Cell Lymphoma (DLBCL). We will go all the important details on this aggressive NHL which can be highly curable. We have some new changes since we last covered this topic in 2022 including a new category 1 option for advanced DLBCL -
Wellness in Oncology with Dr. Laura Vater 13.07.2026 23Min.This week’s episode we are back with our very special guest, friend and colleague Dr Laura Vater joining us to talk about wellness in oncology, and burnout prevention tips. -
Transitioning from Fellow to Attending with Dr. Laura Vater 29.06.2026 19Min.This week’s episode we have a very special guest, friend and colleague Dr. Laura Vater joining us to talk about one of the biggest transitions in medicine—moving from fellow to attending. Dr Vater is a GI oncologist at IU, writer, and speaker. She focuses on the dignity of patients and clinicians, and strives to keep healthcare human. -
ASCO 2026 Plenary: SARC-041 22.06.2026 11Min.This week’s episode will be focusing on an ASCO 2026 Plenary abstract, SARC 041. SARC041 is the first positive phase 3 randomized controlled trial of a CDK4/6 inhibitor in advanced dedifferentiated liposarcoma (DDLPS), demonstrating that abemaciclib significantly improves progression-free survival compared to placebo. -
ASCO Annual Meeting 2026 GU Recap 15.06.2026 14Min.Today we are recapping exciting GU data presented at the 2026 ASCO Annual Meeting in bladder cancer, kidney cancer, and prostate cancer. -
ASCO 2026 Plenary: RASolute-302 08.06.2026 11Min.This week’s episode will be focusing on the 2026 ASCO Plenary that received a standing ovation, the RASolute 302 trial. The RASolute 302 trial is a landmark phase 3 study demonstrating that daraxonrasib doubled overall survival compared to chemotherapy in previously treated (2L) metastatic pancreatic ductal adenocarcinoma (mPDAC). -
ASCO Annual Meeting 2026 Preview 25.05.2026 11Min.Today we will be focusing on exciting data to come at the ASCO Annual Meeting in 2026 in Chicago, with a special focus on GU sessions, educational sessions & med ed sessions. -
Von Willebrand Disease (VWD) 2026 UPDATE 18.05.2026 13Min.This week’s episode will be focusing on Von Willebrand disease (VWD), a highly testable bleeding disorder. We will go over all the important details on the diagnosis, types of VWD as well as treatment. -
Aplastic Anemia 2026 UPDATE 11.05.2026 11Min.Today’s episode is focusing on the highest yield facts about Aplastic Anemia. This will include the mechanism of AA, diagnostic work-up, treatment of AA, and the evolution of clones including PNH. -
Metastatic Bladder Cancer 2026 UPDATE 04.05.2026 9Min.Today’s episode is focusing on what you need to know regarding metastatic bladder cancer, with 2026 updates. This will include the need to know treatment options and toxicities for metastatic urothelial carcinoma, and also discuss the management of upper tract + variant non-urothelial histology. -
Localized Bladder Cancer 2026 UPDATE 27.04.2026 13Min.Today’s episode is focusing on what you need to know regarding localized bladder cancer, with 2026 updates. This will include the need to know pathology, presentation, diagnostic work-up, staging, and treatment options.
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