Deep Margin

Episodios

• Episode 22: Superstar Nancy Lee talks us through hypoxia, functional imaging and the future of deescalation! 14.06.2026 43m

  Another rockstar joins us for a great episode talking through some of the advances in head and neck de-escalation
• Episode 14 [PART 2]: Chris Holsinger, the robot, E3311; the definitive piece 14.06.2026 39m

  We're back with Chris Holsinger for part 2 of the TORS adventure
• Episode 21: Alan Ho live (post hoc) from the Multidisciplinary Head and Neck Cancers Symposium 31.05.2026 39m

  Alan Ho, Medical oncologist at MSKCC talks us through his work around Ozuriftamab Vedotin (Oz-V) and other ADC approaches. Ben criticises Will's combination approaches.
• Episode 20: PAPER OF THE MONTH Nadeem Riaz talks us through cellular mechanisms of resistance, cluster f**ks and all the ecosystem. 17.05.2026 46m

  Nadeem Riaz directs the Precision Radiotherapy Initiative and leads a multidisciplinary research lab at the intersection of the DNA damage response and anti-tumor immunity. He talks us through his important paper examining mechanisms of resistance and some of the pitfalls of academia.
• Episode 19: NIVOPOSTOP - nivolumab post op - a GORTEC triump with Yungan Tao 11.05.2026 38m

  Yungan Tao President-Elect GORTEC, and Radiation Oncologist in Head and Neck cancer at Institut Gustave-Roussy talks us through the NICOPOSTOP trial. Will risks diplomatic incidents and out European tour continues.
• Episode 18: Our man in Denmark: Jeppe Friborg talks us through DAHANCA/Vores mand i Danmark: Jeppe Friborg taler os gennem DAHANCA 04.05.2026 38m

  The Danish Head and Neck Cancer (DAHANCA) group was established in 1976 as a working group by the Danish Society for Head and Neck Oncology. Since it has gone from strength to strength and continues to pioneer cooperative group research on a national scale! Current head Jeppe Friborg talks us through their up and coming work. Den danske gruppe for hoved- og halskræft (DAHANCA) blev etableret i 1976 som en arbejdsgruppe under Dansk Selskab for Hoved- og Halsonkologi. Siden da er gruppen gået fra styrke til styrke og fortsætter med at være pionerer inden for kooperativ gruppeforskning på nationalt plan! Nuværende leder, Jeppe Friborg, fortæller os om deres kommende arbejde.
• Episode 16: PAPER OF THE MONTH ALERT! Immune boost HPV with Mr Meta-Analysis himself Pr Pierre Blanchard 20.04.2026 42m

  Pierre Blanchard, Professor at Gustave Roussy and Editor of Radiotherapy and Oncology 'the green journal' joins us to discuss his recent trial
• Episode 17: Nabil Saba talks us through sinonasal cancer 20.04.2026 50m

  Professor and Vice-chair of Hematology and Medical Oncology, and Professor of Otolaryngology at the Winship Cancer Institute at the Emory University School of Medicine in Atlanta, Georgia. He talks us through sinonasal histologies . Ben refers Will to social services.
• Episode 15: Don't mention the 'P' word; long term functional outcomes with Professor Kate Hutcheson 12.04.2026 50m

  Superstar Kate Hutcheson, Professor in the  Department of Head and Neck Surgery at The University of Texas MD Anderson  Cancer Center. and Director of Speech Pathology and Audiology talks to us about long term outcomes and examines Will's literacy.
• Episode 14 [PART 1] : ding ding round 2 in the red corner it's Chris Holsinger live with the E3311 trial and TORS adventures 03.04.2026 31m

  Chris Holsinger from Stanford gets grilled by Ben and Will on TORS history in this part 1/2 episode.
• Episode 13: Ding Ding: TORS round 1 - the blue corner we have Professor David Palma talking about RT 02.03.2026 42m

  We talk ORATOR, ORATOR 2 and the genesis of evidence in TORS!
• Episode 12: The Nasopharyngeal Gardener talks ctDNA with Dr Melvin Chua 22.02.2026 38m

  Melvin Chua joins the deeply marginal crowd to talk EBV ctDNA, its clinical use, science, gardening and islands.
• Episode 11: Radiotherapy Revolutions with Professor Chris Nutting 16.02.2026 37m

  Chris Nutting, Professor of Radiotherapy and leader on many pivotal trials at the ICR joins us to talk through the past 25 years of radiotherapy advances and the data underpinning these. We talk about the future and Will has some technical difficulties so there is less nonsense than usual!
• Episode 10: The Rockstar talks ctDNA with Dr Glenn Hanna 09.02.2026 53m

  Dr Glenn Hanna, Director of the Center for Cancer Therapeutic Innovation (CCTI) at Dana Faber Cancer Insitute joins us for our 10th episode and it's a cracker; Glenn talks us through the finer points of ctDNA, MRD and what the future holds for this exciting space.  
• Episode 9: Salvage surgery and red lines with Vin Paleri 31.01.2026 41m

  Professor Vin Paleri, Consultant Head and Neck Surgeon at The Royal Marsden Hospitals and Professor of Head and Neck Surgery at the Institute of Cancer Research talks us through salvage surgery data, patient selection and how to tame feral oncologists.
• Episode 8: Paul Swiecicki, bispecifics and other unpronouncables! 12.01.2026 37m

  Paul Swieciki, Associate Professor from Michigan joins us for a deep dive into bispecifics. We talk future targets, current excitiement and Ben gets excited about merchandise and a potential grudge match with friend of the show hardman Ari Rosenberg. It's a belter!
• Episode 7: Immuno-radiotherapy with Swashbuckling David Sher, the node whisperer 21.12.2025 53m

  David Sher, Medical Director of Radiation Oncology, Chief of Head and Neck Radiation Oncology Service at UT Southwestern joins us for a comprehensive discussion about radiotherapy and its interaction with the immune system. We cover SABR, perioperative trials and elective node irradiation; it's quite a journey!
• Episode 6: Schilling's Sentinels; Sentinel lymph node biopsy in HNSCC and management of the clinically N0 neck with Clare Schilling 16.12.2025 42m

  Clare Schilling, Consultant oral and maxillofacial surgeon and honorary associate professor at the University College London Head and Neck Academic Centre (HNAC) joins us live from Birmingham, where Ben likes to holiday. We talk Weiss, D'Cruz, risk and the future. Clare invites Will and Ben to 'have a go at it' too -it's a real blast!
• Episode 5: Xevinapant, X-rays and Xmas is coming with Jonathan Schoenfeld 01.12.2025 44m

  Jonathan Shoenfeld Director of Head and Neck and Melanoma Radiation Oncology at Dana-Farber Brigham Cancer Center, and MGB Endowed Chair in Radiation Oncology joins us for some apoptotic inhibitory catharsis and takes us down his Cambridge memory lane!
• Episode 4: Perioperative promises (KEYNOTE 689 and NIVOPOSTOP) with Ravi Uppaluri 26.11.2025 53m

  Ravi Uppalauri, Director of Head and Neck Surgical Oncology at the Brigham and Women’s Hospital and Dana-Farber Cancer Institute, talks us through his views on 2025's important perioperative trials. Ben leaps like a salmon.