MeSsy with Christina Applegate & Jamie Lynn Sigler

Episodios

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  Stop Apologizing for Wanting More with Heather Dubrow 17.09.2026 54m

  This week on Living With It, Jamie sits down with Heather Dubrow for an honest conversation about embracing life’s pivots, protecting your peace, and giving yourself permission to want more.
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  There Is Beauty Within All of This Pain with Lindsey Kraft 15.09.2026 54m

  This week on MeSsy, Jamie sits down with her longtime friend, actress, writer, and musician Lindsey Kraft. They talk about growing up together, navigating rejection and self-doubt, and Lindsey’s unexpected journey from acting to writing her own one-woman musical.
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  Falling Apart to Come Back Together with Ryan Weiss 10.09.2026 47m

  This week on Living With It, Jamie sits down with her friend, Ryan Weiss. They talk about letting go of control, sitting with difficult emotions, knowing when it’s time to do things differently, and learning to trust what’s on the other side when life doesn’t look the way you thought it would.
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  Thank God I’m So Neurotic with Cat Cohen 08.09.2026 47m

  This week on MeSsy, Jamie sits down with comedian, actor, and singer Cat Cohen. Cat opens up about having a stroke at 31, navigating health anxiety in the aftermath, and turning one of the scariest experiences of her life into her most fulfilling creative work yet.
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  We Fight For Joy with Kelsey Chittick 03.09.2026 53m

  This week on Living With It, Jamie sits down with Kelsey Chittick to talk about losing her husband suddenly, raising two children through grief, and learning to build a life she never expected. They discuss finding humor in the darkest moments, letting go of the life you thought you’d have, the power of community, and how to choose joy.
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  There’s No Place Like Home with Annie Meyers-Shyer 01.09.2026 53m

  This week, Jamie is joined by her longtime friend Annie Meyers-Shyer, the creator behind This Oak House. They talk about Annie’s unexpected second act, finding a new passion and career at 45, and why it’s never too late to bet on yourself. Annie also shares how she creates a home that feels like an exhale, the small ways our spaces can support us through difficult seasons, and how her home carried her through grief.
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  The Power of Radical Acceptance with Jim Curtis 27.08.2026 53m

  This week on Living With It, Jamie sits down with Jim Curtis, a transformational coach, author, and wellness leader. They discuss how to radically accept the life you have without giving up hope for the life you want, the stories we build around our suffering, and learning to see your body as an ally instead of the enemy. Plus, Jim shares how releasing old beliefs and changing the way we speak to ourselves can open us up to new possibilities.
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  Jamie's Son Beau 25.08.2026 42m

  This week, Jamie sits down with a very special guest: her 13-year-old son, Beau. They have an honest conversation about what it’s been like growing up with a mom who has MS, how Jamie’s strength has shaped him, and what he wants other kids and parents living with chronic illness to know.
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  Accept, Adapt, Appreciate with Odette Annable 20.08.2026 54m

  This week on Living With It, Jamie sits down with her friend Odette Annable. They discuss parenting a neurodivergent child, trusting your instincts, advocating for your family, and learning to let go of the need to have all the answers.
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  The Courage to Slow Down 18.08.2026 53m

  This week on MeSsy, Jamie opens up about reaching her limit and learning to make rest part of healing. She also reads listener emails about fighting to be heard by doctors, learning to accept help, and the power of knowing you're not alone.
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  Finding Stillness When Life Won’t Slow Down with Bob Roth 13.08.2026 1h

  This week on Living With It, Jamie sits down with Bob Roth, a leading Transcendental Meditation teacher and CEO of the David Lynch Foundation. They discuss what stress does to the body, how meditation can help calm the nervous system, and how finding stillness can help us navigate uncertainty, illness, and everyday life.
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  How Death Informs How We Live with Julie McFadden 11.08.2026 58m

  This week, Jamie sits down with hospice nurse Julie McFadden to talk about changing the way we think about death, what she’s learned from those at the end of life, and how accepting our mortality can help us live more fully in the present.
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  Trusting the Journey with Becca Tobin 06.08.2026 57m

  This week, Jamie sits down with one of her best friends, Becca Tobin, for a conversation about infertility, pregnancy loss, surrogacy, and finding hope after years of uncertainty. They explore grief, resilience, the unexpected paths to parenthood, and what it means to keep moving forward when life doesn't unfold the way you imagined.
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  Try to Find the Light with Amanda Kloots 04.08.2026 59m

  This week, Jamie sits down with Amanda Kloots for an honest conversation about finding joy alongside heartbreak. Amanda opens up about losing her husband, Nick Cordero, how her grief has evolved over the past six years, why she no longer believes we have to "let go" of the people we love, and more.
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  Look for the Signs with Kate Doerge 30.07.2026 58m

  On this episode of Living With It, Jamie sits down with Kate Doerge to discuss finding hope after profound loss, recognizing signs from loved ones, and the five actions that can transform the way we move through grief.
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  Hope Can Exist Alongside Fear with Myriam Sandler 28.07.2026 1h 7m

  This week, Jamie sits down with Mothercould creator Myriam Sandler. They discuss her recent MS diagnosis, trusting your intuition, and finding hope even when life doesn't go as planned.
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  It's Okay Not to Be Okay with Amy Kurtz 23.07.2026 55m

  On the first episode of Living With It, Jamie sits down with Amy Kurtz, a patient advocate and author. They discuss the grief of chronic illness, learning to trust yourself again, and why healing is about so much more than getting better.
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  All Eyes on Me 21.07.2026 48m

  This week, Jamie reads listener emails and opens up about the feeling of all eyes on you when you're struggling, the anxiety of the lead up, caregiving, and more. Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: Novartis in neuroscience - Our ambition is to create a transformational impact for people living with severe neurological conditions and their caregivers by discovering, developing and delivering innovative medicines that change the course of disease progression. CBDistillery - Visit https://CBDistillery.com and use my code MESSY for 25% off. That’s C B Distillery dot com, code MESSY C B Distillery dot com. ZocDoc  -Head to https://Zocdoc.com/MESSY to get started and check that appointment off your to-do list! Radiance -For 20% off and FREE SHIPPING. Go to https://BRICKHOUSENUTRITION.com and use code - MESSY Lola Blankets  -Get 40% off select Lola Blankets products at https://Lolablankets.com by using code MESSY at checkout. Experience the world’s #1 blanket with Lola Blankets.
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  Tamsen Fadal 14.07.2026 56m

  This week, Jamie sits down with journalist, author, and menopause advocate Tamsen Fadal. They discuss the physical and emotional realities of perimenopause, why so many women feel dismissed by the medical system, and how speaking honestly about aging, identity, and women's health can help us all feel less alone. Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: Novartis in neuroscience - Our ambition is to create a transformational impact for people living with severe neurological conditions and their caregivers by discovering, developing and delivering innovative medicines that change the course of disease progression. Veracity - For up to 65% off your order, head to https://VeracityHealth.co and use code MESSY. Rythm - Right now, Rythm is offering our listeners 15% off your first month and free shipping at ⁠https://rythm.health/messy⁠   Stop guessing, start testing. Rythm DOT HEALTH slash messy    Jones Road - Use code MESS at jonesroadbeauty.com to get a Free Gift with your first purchase! #JonesRoadBeauty #ad
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  You Do Not Have to Become Someone Else to Heal 07.07.2026 51m

  This week, Jamie reads listener emails and discusses the invisible weight of living with chronic illness, the courage it takes to keep showing up, and the small moments that can bring us back to ourselves. She also shares the reminder she received from a recent on stage performance. Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: Novartis in neuroscience - Our ambition is to create a transformational impact for people living with severe neurological conditions and their caregivers by discovering, developing and delivering innovative medicines that change the course of disease progression. Zbiotics - Go to  https://zbiotics.com/MESSY and use MESSY at checkout for 15% off any first time orders of ZBiotics probiotics. Honeylove - Save 20% Off Honeylove by going to https://honeylove.com/messy #honeylovepod Rythm - Right now, Rythm is offering our listeners 15% off your first month and free shipping at https://rythm.health/messy   Stop guessing, start testing. Rythm DOT HEALTH slash messy