American Journal of Psychiatry Audio

Episodios

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  July 2026: Social Determinants of Health in Psychiatric Disorders: Exciting Opportunities for Biopsychosocial Research and Clinical Care 01.07.2026 37m

  Dr. Dilip Jeste (Social Determinants of Health Network, La Jolla, CA) joins the podcast to discuss how social determinants of health interact with treatment for psychiatric disorders.  Afterwards, AJP Editor-in-Chief Dr. Ned Kalin once again puts the rest of the July issue into context. 00:31     Impacts of social determinants of health on psychiatric disorders, research, and clinical care 04:43     Health related social needs versus social determinants of health 08:47     Loneliness as a risk factor 12:36     A clinician's role in societal factors 14:47     Mechanistic understandings social determinants and the exposome 18:17     Further research 22:25     Kalin interview 22:30     Jeste and Gyan 23:33     Blundell et al. 28:03     Yang et al. 32:20     Van der Meer et al. Transcript Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it. Subscribe to the podcast here. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. How authors may submit their work. Follow the journals of APA Publishing on Twitter. E-mail us at ajp@psych.org
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  June 2026: Low-Dose Buprenorphine Following Ketamine Treatment for Suicidal Ideation in Major Depressive Disorder: A Randomized, Double-Blind, Placebo-Controlled Trial 01.06.2026 29m

  Dr. Jason Tucciarone and Dr. Alan Schatzberg (Stanford University, Stanford, CA) join AJP Audio to discuss the use of low-dose buprenorphine as an adjunctive therapy to extend the anti-suicidal effects of ketamine treatment in patients with major depressive disorder and suicidal ideation.  AJP Editor-in-Chief Dr. Ned Kalin joins to discuss the rest of the June issue of the Journal, which takes a close look at issues surrounding suicide and severe depression. 01:20     Tucciarone and Schatzberg interview 03:36     Disparity between effects on suicidal ideation and antidepressant ratings 05:36     Ethics of placebo and ketamine in patients with suicidal ideation 08:28     Immediate clinical implications 11:40     Limitations 14:10     Further research 16:19     Kalin interview 16:24     Tucciarone et al. 20:39     Rovers et al. 24:30     Jelen et al. Transcript Board-certified psychiatrists, if you're seeking meaningful inpatient work with real clinical autonomy, consider becoming the Clinical Director for a 16-bed behavioral health hospital in Fergus Falls or Bemidji, Minnesota. You'll lead a supportive interdisciplinary team, enjoy predictable work-life balance, and have opportunities for teaching and mentorship without RVU pressure or third-party billing. Learn more on APA's Career Center, JobCentral, by searching Direct Care and Treatment – State of Minnesota. Direct Care and Treatment – State of Minnesota:  bit.ly/DCTClinicalDirector Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it. Subscribe to the podcast here. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. How authors may submit their work. Follow the journals of APA Publishing on Twitter. E-mail us at ajp@psych.org
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  Special Episode: The Future of DSM 15.05.2026 22m

  In this special episode of AJP Audio, AJP Editor-in-Chief Dr. Ned Kalin is joined by Dr. María Oquendo (Perelman School of Medicine at the University of Pennsylvania, Philadelphia), chair of APA's Future DSM Strategic Committee to discuss a series of commentaries published in the May issue of the Journal discussing the strategic vision for the future of DSM. 00:39   Oquendo interview 03:07   Size of the response 04:18   Feedback 06:04   Incorporating the feedback 07:57   Emphasizing science with a title change for DSM 10:18   A living document 12:35   Changes from previous versions of DSM 16:08   Changes in documentation and coding 18:51   Lived experience 20:02   Working with AJP Links to the commentaries:  Initial Strategy for the Future of DSMMaría A. Oquendo, M.D., Ph.D., et al. The Future of DSM: A Report From the Structure and Dimensions SubcommitteeDost Öngür, M.D., Ph.D., et al. The Future of DSM: Are Functioning and Quality of Life Essential Elements of a Complete Psychiatric Diagnosis?Karen Drexler, M.D., et al. The Future of DSM: Role of Candidate Biomarkers and Biological FactorsBruce Cuthbert, Ph.D., et al. The Future of DSM: A Strategic Vision for Incorporating Socioeconomic, Cultural, and Environmental Determinants and IntersectionalityMilton L. Wainberg, M.D., et al. Transcript Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it. Subscribe to the podcast here. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. How authors may submit their work. Follow the journals of APA Publishing on Twitter. E-mail us at ajp@psych.org
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  May 2026: Psychiatric Comorbidities in Substance Use Disorders: Sex-Based Differences in a National Real-World Clinical Sample 01.05.2026 30m

  Dr. Eduardo Butelman (Icahn School of Medicine at Mount Sinai, New York) joins AJP Audio to discuss the varying incidence of psychiatric comorbidities across patients diagnosed with substance use disorders.  Afterwards, AJP Editor-in-Chief Dr. Ned Kalin joins the podcast to discuss the rest of the May issue, which includes a discussion on the future of the DSM. 00:53     Butelman interview 02:23     Mechanisms of difference between males and females 04:04     Patterns of response between males and females in substance use disorders 05:54     Implications for research into sex-based differences 07:33     Racial and ethnic variations in findings 09:30     Limitations 10:46     Immediate clinical implications? 12:09     Further research 13:18     Kalin interview 13:38     Butelman et al. 17:11     Hinojosa et al. 22:49     van Rooij et al. 26:06     The future of DSM Transcript Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it. Subscribe to the podcast here. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. How authors may submit their work. Follow the journals of APA Publishing on Twitter. E-mail us at ajp@psych.org
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  April 2026: Mobile Health for Alcohol Use Assessment: Longitudinal Effects of Breathalyzer Self-Monitoring in Everyday Contexts 01.04.2026 35m

  Yang Lu, M.S., and Catharine E. Fairbairn, Ph.D. (University of Illinois, Urbana-Champaign) join AJP Audio to discuss the longitudinal effects of the use of personal alcohol breathalyzers in a natural setting on alcohol usage. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin joins the podcast to discuss the rest of the April issue, which focuses on subjects related to substance use disorders. 00:57     What did you discover about the long term effects of using a personal blood alcohol monitor? 03:12     Do health monitoring devices actually change behaviors? 04:10     What did your cohort look like? 08:49     Disparate impact of monitoring on heavy drinkers and light drinkers 11:36     Clinical implications 14:34     Limitations 15:46     Avenues for further research 18:39     Kalin interview 18:46     Lu et al. 24:00     Wittekind et al. 29:50     Nicholson et al. Transcript Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it. Subscribe to the podcast here. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. How authors may submit their work. Follow the journals of APA Publishing on Twitter. E-mail us at ajp@psych.org
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  March 2026: Primary Prevention of PTSD Symptoms in Combat-Deploying Soldiers Using Attention Bias Modification: A Randomized Controlled Trial 01.03.2026 33m

  Chelsea Dyan Gober Dykan, M.A. (Tel Aviv University, Israel), joins AJP Audio to discuss a study looking at two versions of attention bias modification with an eye towards a prophylactic impact on developing PTSD in a cohort of combat-bound soldiers.  Afterwards, AJP Editor-in-Chief Dr. Ned Kalin joins the podcast to put the rest of the March issue into context. 00:57   Attention bias modifications 03:54   Response-time and gaze-contingent paradigms 05:05   Differences in efficacy between the two arms 08:06   Ethical considerations in investigating combat-bound soldiers 10:44   Controlling for combat experiences in studying PTSD 12:24   Duration of the effect 13:44   Limitations 15:03   Immediate clinical implications 16:22   Further research 17:05   Kalin interview 17:22   Dykan et al. 21:03   Kaul et al. 26:19   Kantrowitz et al. Transcript Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it. Subscribe to the podcast here. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. How authors may submit their work. Follow the journals of APA Publishing on Twitter. E-mail us at ajp@psych.org
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  February 2026: Doxycycline Use in Adolescent Psychiatric Patients and Risk of Schizophrenia: An Emulated Target Trial 01.02.2026 29m

  Dr. Ian Kelleher (University of Edinburgh, Scotland) joins AJP Audio to discuss an emulated target trial looking at the prophylactic qualities of doxycycline, an antibiotic, in an adolescent population at risk to develop schizophrenia spectrum disorder.  Afterwards, AJP Editor-in-Chief Dr. Ned Kalin joins the podcast to put the rest of the issue into context. 00:53   Doxycycline and the risk of developing schizophrenia 04:03   Emulated target trials versus randomized control trials 06:43   Methods of action 09:24   Dosage and exposure levels for doxycycline 10:15   Immediate clinical applications 10:56   Limitations of the study 11:33   Future research 12:43   Kalin interview 13:00   Lång et al. 19:43   Zhao et al. 25:20   Metrik et al. Transcript Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it. Subscribe to the podcast here. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. How authors may submit their work. Follow the journals of APA Publishing on Twitter. E-mail us at ajp@psych.org
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  Special Episode: 2025 Articles of Import and Impact 23.01.2026 33m

  This special episode of AJP Audio brings together the editors of the American Journal Psychiatry and the AJP Residents' Journal to discuss important and impactful articles published in 2025. 00:39   Ned H. Kalin, M.D., discusses "Transcriptomic Analysis of the Human Habenula in Schizophrenia" by Ege A. Yalcinbas, Ph.D., et al. 06:23   Elisabeth Binder, M.D., Ph.D., discusses "Copy Number Variant Architecture of Child Psychopathology and Cognitive Development in the ABCD Study" by Zhiqiang Sha, Ph.D., et al. 11:17   Kathleen T. Brady, M.D., Ph.D., discusses "High-Potency Cannabis Use and Health: A Systematic Review of Observational and Experimental Studies" by Stephanie Lake, Ph.D., et al. 15:35   David A. Lewis, M.D., discusses "20 Years of Aberrant Salience in Psychosis: What Have We Learned?" by Philip R. Corlett, Ph.D., and Kurt M. Fraser, Ph.D. 17:27   William M. McDonald, M.D., discusses "Psychedelics for the Treatment of Psychiatric Disorders: Interpreting and Translating Available Evidence and Guidance for Future Research" by Roger S. McIntyre, M.D., F.R.C.P.C., et al. 24:04   Daniel S. Pine, M.D., discusses "Cognitive Behavioral Therapy and Lisdexamfetamine, Alone and Combined, for Binge-Eating Disorder With Obesity: A Randomized Controlled Trial" by Carlos M. Grilo, Ph.D., et al. 26:06   Carolyn Rodriguez, M.D., Ph.D., discusses "Randomized Controlled Trial of the Effects of High-Dose Ondansetron on Clinical Symptoms and Brain Connectivity in Obsessive-Compulsive and Tic Disorders" by Emily R. Stern, Ph.D., et al. 30:26   Sean T. Lynch, M.D., discusses "From Medical Practice to Mass Incarceration: A Historical Analysis of Racial and Ethnic Targeting in U.S. Drug Policy" by Rathisha Pathmathasan, D.O., et al. Transcript Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it. Subscribe to the podcast here. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. How authors may submit their work. Follow the journals of APA Publishing on Twitter. E-mail us at ajp@psych.org  
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  January 2026: Reduced Threat-Related Neural Efficiency: A Possible Biomarker for Pediatric Anxiety Disorders 01.01.2026 26m

  Dr. Julia Linke (University of Mainz, Germany) joins AJP Audio to discuss the use of neural efficiency, a measure of brain activity, as a potential biomarker in the treatment of children with anxiety disorder.  Afterwards, AJP Editor-in-Chief Dr. Ned Kalin joins the podcast to put the rest of the issue into context. 00:31   Linke interview 02:15   State or a trait? 04:15   Neural efficiency and CBT 05:22   Potential as a biomarker 07:08   Patient-rated and parent-rated measures of anxiety 08:16   Immediate clinical implications 09:50   Limitations 10:43   Future directions of research 11:44   Kalin interview 11:50   Linke et al. 15:16   Mallard et al. 18:11   Naples et al. 21:44   Mac Giollabhui et al. Transcript Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it. Subscribe to the podcast here. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. How authors may submit their work. Follow the journals of APA Publishing on Twitter. E-mail us at ajp@psych.org
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  December 2025: Adjunctive Lumateperone in Patients With Major Depressive Disorder: Results From a Randomized, Double-Blind, Phase 3 Trial 01.12.2025 22m

  Dr. Suresh Durgam (Intra-Cellular Therapies, a Johnson & Johnson Company, Bedminster, NJ) joins AJP Audio to discuss a phase 3 randomized controlled trial looking at the use of the antipsychotic medication lumateperone as adjunctive to antidepressant therapy in the treatment of patients with major depressive disorder. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin discusses the rest of the December issue of the Journal. 00:48   Durgam interview 03:09   Mechanism of action 04:44   Patient-reported outcomes 06:31   Immediate clinical implications 07:32   Limitations 08:08   Further research 09:25   Kalin interview 09:38   Durgam et al. 13:09   Lin et al. 17:22   Brodsky et al. Transcript Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it. Subscribe to the podcast here. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. How authors may submit their work. Follow the journals of APA Publishing on Twitter. E-mail us at ajp@psych.org
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  November 2025: Contingency Management for Stimulant Use Disorder and Association With Mortality: A Cohort Study 01.11.2025 27m

  Dr. Lara Coughlin (University of Michigan, Ann Arbor) joins AJP Audio to discuss a study looking the impact of contingency management on all cause mortality in patients with stimulant use disorder. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin discusses the rest of the November issue of the Journal. 01:09   Coughlin interview 02:05   Stimulant use disorder and contingency management 04:37   Mortality 05:12   Contingency management and "moral hazard" 08:30   Clinical uptake of contingency management 09:28   Broader applicability to psychiatric conditions 10:31   Limitations 11:39   Further research 12:32   Kalin interview 12:49   Coughlin et al. 16:41   Yalcinbas et al. 22:22   Na et al. Transcript Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it. Subscribe to the podcast here. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. How authors may submit their work. Follow the journals of APA Publishing on Twitter. E-mail us at ajp@psych.org
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  October 2025: Differential Effects of Ovarian Steroids in Women With and Without Premenstrual Dysphoric Disorder: A Replication and Extension of Findings 01.10.2025 26m

  Dr. Shau-Ming Wei (National Institute of Mental Health, Bethesda, MD) joins AJP Audio to discuss a replication study looking at impact of hormone addback to a hormone suppression regimen for the treatment of premenstrual dysphoric disorder. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin discusses the rest of the October issue of the Journal.  00:34   Wei interview 02:59   PMDD 04:22   Up and downsides of hormone suppression 05:52   Hormone addback 07:15   Limitations of the current study 08:38   Further research 10:42   Kalin interview 10:58   Wei et al. 15:25   Sanacora et al. 20:07   Whittle et al. 23:06   Cooper et al. Transcript Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it. Subscribe to the podcast here. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. How authors may submit their work. Follow the journals of APA Publishing on Twitter. E-mail us at ajp@psych.org
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  September 2025: Neighborhood Social Vulnerability and Racial Disparities in Schizophrenia Spectrum Disorder Prevalence 01.09.2025 39m

  Dr. Deidre Anglin (City College, CUNY, New York) joins AJP Audio to discuss the disparate impact of schizophrenia spectrum disorder diagnosis on racial and ethnic minorities in the United States based on localized neighborhood data. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin discusses the rest of the September issue of the Journal. 00:31   Anglin interview 04:40   Zip code sizes 05:18   The long legacy of redlining 07:17   Socially vulnerable neighborhoods 09:43   Structural racism, clinicians, and working with individuals 13:45   Limitations 15:56   Further research 18:08   Kalin interview 18:13   Anglin et al. 25:19   Vano et al. 29:40   Moussa-Tooks et al. 33:34   Zhang et al. Transcript Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it. Subscribe to the podcast here. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. How authors may submit their work. Follow the journals of APA Publishing on Twitter. E-mail us at ajp@psych.org
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  August 2025: Telehealth Prescribing of Stimulants for ADHD and Associated Risk for Later Stimulant and Substance Use Disorders 01.08.2025 33m

  Dr. Vinod Rao (Massachusetts General Hospital, Boston) join AJP Audio to discuss predicting the relative risk of patients with an ADHD diagnosis developing a later stimulant or substance use disorder based on the method of prescription, in person or via telehealth. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin discusses the rest of the August issue of the Journal. 00:07   Rao interview 01:53   Stimulant use disorder versus substance use disorder 02:59   Cohort size and incidence of SUDs 04:28   Length of clinician engagement in non-profit versus for profit hospital systems 05:18   Patient cohort 06:20   Potential difference in mechanism between prescribing practices 07:35   Continued use of telehealth 08:43   Limitations 10:03   Further research 11:17   Kalin interview 11:24   Rao et al. 15:41   Mahjani et al. 19:59   Zhang et al. 25:11   Sha et al. 29:33   Gao and Olfson Transcript Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it. Subscribe to the podcast here. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. How authors may submit their work. Follow the journals of APA Publishing on Twitter. E-mail us at ajp@psych.org
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  July 2025: National Trends in Suicidal Thoughts and Suicide Attempts Among High School Students in the United States 01.07.2025 24m

  Dr. Tanner Bommersbach (University of Wisconsin School of Medicine and Public Health) and Dr. Greg Rhee (University of Connecticut and Yale University School of Medicine) join AJP Audio to discuss estimating national trends in suicidal ideation and attempts in high school students with and without accompanying high-risk behaviors.  Afterwards, AJP Editor-in-Chief Dr. Ned Kalin discusses the rest of the July issue of the Journal. 00:07   Bommersbach and Rhee interview 00:36   Trends in suicide among high school students in the US 02:49   Variation in rates based on gender, racial identity, and sexuality 03:50   Did the rates increase during the COVID-19 pandemic? 04:14   Lessons to be learned from COVID? 05:23   Behavior risk factors 06:33   Clinical implications 08:19   Inflections in risk factors due to the pandemic? 08:52   Limitations 09:32   Future research 10:16   Kalin interview 10:31   Bommersbach et al. 14:20   Müller et al. 18:54   Ahn et al. 21:47   McCabe et al. Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it. Subscribe to the podcast here. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. How authors may submit their work. Follow the journals of APA Publishing on Twitter. E-mail us at ajp@psych.org
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  June 2025: Stratifying Risk for Postpartum Depression at Time of Hospital Discharge 01.06.2025 32m

  Dr. Roy Perlis (Mass General Bringham, Boston) joins AJP Audio to discuss a machine learning model to examine electronic health records in individuals who had recently given birth designed to detect those who might develop postpartum depression.  Afterwards, AJP Editor-in-Chief Dr. Ned Kalin puts the rest of the June issue into context. 00:31     Perlis interview 02:56     Lack of validation in screening methods 04:03     Stumbling blocks on the road to validation 05:10     Synergy between screening scores and machine learning models 06:36     Issues with clinician adoption? 08:44     Administrative burden for running these models 10:38     Current clinical application 12:37     Screening without those with a history of depression 13:48     Limitations 15:30     Future research 17:26     Kalin interview 17:41     Clapp et al. 21:41     Kępińska et al. 25:19     Savitz et al. 25:25     Miller 28:38     Wall et al. Transcript Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it. Subscribe to the podcast here. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. How authors may submit their work. Follow the journals of APA Publishing on Twitter. E-mail us at ajp@psych.org
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  May 2025: Randomized Controlled Trial of "Bounce Back Now," a Mobile App to Reduce Post-Disaster Symptoms of Posttraumatic Stress, Depressed Mood, and Sleep Disturbance 01.05.2025 36m

  Dr. Kenneth Ruggiero (Medical University of South Carolina, Charleston) joins AJP Audio to discuss the the effectiveness of an app-based intervention at reducing the symptoms of sleeplessness and posttraumatic stress in a broad cohort in the wake of a natural disaster.  Afterwards, AJP Editor-in-Chief Dr. Ned Kalin puts the rest of the May issue into context. 00:38     Ruggiero interview 03:13     Bounce Back Now app 05:03     Natural disasters and other sources of trauma 07:31     Low cost and broad-based intervention 08:49     Limitations 10:19     Changes in how the intervention was designed 11:17     Uptake and interactions with the app 13:15     Future directions 14:36     Kalin interview 14:50     Ruggiero et al. 19:26     Norman et al. 23:29     Conrod et al. 27:53     Olfson et al. 31:44     Olfson et al. Transcript Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it. Subscribe to the podcast here. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. How authors may submit their work. Follow the journals of APA Publishing on Twitter. E-mail us at ajp@psych.org
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  April 2025: Anticholinergic Burden and Cognitive Function in Psychosis: A Systematic Review and Meta-Analysis 01.04.2025 23m

  Dr. Valentina Mancini (Oxford University) joins AJP Audio to discuss the impact of anticholinergic burden on cognition in patients with schizophrenia.  Afterwards, AJP Editor-in-Chief Dr. Ned Kalin puts the rest of the March issue into context. 00:32     Mancini interview 02:26     Anticholinergic burden method of action 02:58     Balancing the impact of side effects in schizophrenia treatment 04:52     Limitations 05:34     The need for further studies 05:59     Clinical implications 06:32     Further research 07:01     Trials needed 07:54     Kalin interview 08:03     Mancini et al. 11:23     Tiihonen et al. 13:43     Zhou et al. 16:28     Omlor et al. 18:51     Orhan et al. Transcript Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it. Subscribe to the podcast here. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. How authors may submit their work. Follow the journals of APA Publishing on Twitter. E-mail us at ajp@psych.org
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  March 2025: The Impact of Xanomeline and Trospium Chloride on Cognitive Impairment in Acute Schizophrenia: Replication in Pooled Data From Two Phase 3 Trials 01.03.2025 32m

  Dr. William Horan (Bristol Myers Squibb) joins AJP Audio to discuss a newly approved, novel treatment for schizophrenia spectrum disorder, which has potential impacts for cognition in patients.  Afterwards, AJP Editor-in-Chief Dr. Ned Kalin puts the rest of the March issue into context. 00:45     Horan interview 03:15     Novel mechanism of action in the treatment of schizophrenia 05:39     Side effect profiles 07:20     Clinical impacts 08:31     The need for further investigation 09:58     Limitations 11:05     Further research 13:08     Kalin interview 13:21     Horan et al. 17:34     Levenstein et al. 19:00     Fountoulakis et al. 20:57     Couture et al. 23:18     Stern et al. 27:35     McGirr et al. Transcript Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it. Subscribe to the podcast here. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. How authors may submit their work. Follow the journals of APA Publishing on Twitter. E-mail us at ajp@psych.org
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  February 2025: Real-Time Assessment of Alcohol Reward, Stimulation, and Negative Affect in Individuals With and Without Alcohol Use Disorder and Depressive Disorders 01.02.2025 44m

  Dr. Andrea King (University of Chicago Medicine) joins AJP Audio to discuss a novel, real time assessment of the reward, stimulation, and negative affect of alcohol use in people with alcohol use disorder with and without depressive disorders.  Afterwards, AJP Editor-in-Chief Dr. Ned Kalin discusses the rest of the February issue, which focuses closely on issues surrounding addiction. 00:35     King interview 00:45     Allostatic model of addiction 02:12     Gathering data and the groups studied 07:37     The ethics of studying alcohol use in patients with AUD 10:38     Findings 13:29     The impacts of alcohol's pleasurable effects on people with AUD and those without 14:32     Limitations of natural environment research versus laboratory research 18:18     Clinical implications 20:09     Further research 22:56     Kalin interview 23:03     King et al. 26:21     Brand et al. 28:12     Conway et al. 32:17     Kypriotakis et al. 35:42     Kuhn et al. 39:37     Grilo et al. Transcript Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it. Subscribe to the podcast here. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. How authors may submit their work. Follow the journals of APA Publishing on Twitter. E-mail us at ajp@psych.org