Cardiology (Video)

Jaksot

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  Heart Regeneration in Humans: Are We There Yet? 26.06.2026 58min

  Heart regeneration faces two connected challenges: replacing lost muscle and keeping transplanted cells safe and accepted by the body. Charles Murry, M.D., Ph.D., of USC explains why the adult heart heals major cardiomyocyte loss with scar tissue rather than new muscle, leading to progressive heart failure. Murry describes how stem cell derived cardiomyocytes can be manufactured at scale, transplanted into injured hearts, and tested for function in animal models. He also examines major barriers, including graft related arrhythmias, calcium handling stress, immune rejection, and the need for practical immunosuppression or immune edited cells. By connecting cell manufacturing, electrophysiology, immunology, and clinical trial planning, this research shows why heart regeneration is difficult and why careful translation matters for patients with severe heart injury. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40853]
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  Cellular Reprogramming in Human Disease 13.09.2025 58min

  Deepak Srivastava, MD, explores how cellular reprogramming offers new hope for treating heart disease. He highlights innovative strategies to regenerate damaged heart tissue by stimulating adult cardiomyocytes to divide and converting fibroblasts into heart-like cells. His team develops a nonviral delivery system using lipid nanoparticles and investigates the role of specific gene regulators in restoring heart function in animal models. Srivastava also discusses a potential oral therapy for aortic valve disease, driven by insights into cellular fate changes caused by NOTCH1 mutations and telomere shortening. Additionally, he reveals how trisomy 21 may trigger congenital heart defects by altering the identity of specialized heart cells. Through pioneering research in genetics and regenerative medicine, Srivastava demonstrates how understanding developmental biology can lead to transformative clinical advances. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40447]
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  Stem Cells and Next Generation Regenerative Medicine Therapies - Medicine Informing Novel Discoveries (MIND) 26.08.2025 59min

  Hear about cutting-edge advances in regenerative medicine, from lab breakthroughs to patient impact. Catriona Jamieson, MD, PhD, introduces efforts at the Sanford Stem Cell Institute to develop therapies that enhance the body’s ability to heal itself. Dan Kaufman, MD, PhD, shares progress in cancer immunotherapy using engineered natural killer cells derived from pluripotent stem cells. Karen Christman, PhD, explains how her team creates injectable hydrogels from pig heart tissue to support heart repair and regeneration after a heart attack. Tiffani Manolis highlights industry support for making cell and gene therapies more accessible. Patient advocate Justin Graves describes his life-changing experience receiving a stem cell-based therapy for epilepsy, underscoring the real-world promise of these innovations. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40705]
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  Managing Lipid Disorders Like High Cholesterol 01.08.2025 58min

  Dr. Robert Baron reviews best practices in lipid management for preventing cardiovascular disease, with a focus on statin use. He outlines the strong evidence for statins in reducing heart attack and stroke risk by 25–33%, particularly in patients with clinical atherosclerotic disease, diabetes, or high LDL. He explains why shared decision-making is key in primary prevention, where guidelines vary and risk thresholds are debated. Baron discusses the shift to the newer PREVENT risk calculator, which offers improved accuracy and removes race as a factor. He also explains when additional lipid-lowering medications may be appropriate and clarifies the impact of risk-enhancing factors like family history, coronary artery calcium, and LP(a). [Health and Medicine] [Show ID: 40755]
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  Diabetes and Cardiovascular Disparities Among Black White and Filipino Women: What's Fat Got to Do with It? 16.07.2024 52min

  Maria Rosario (Happy) G. Araneta, Ph.D., M.P.H., highlights the significant impact of prenatal and childhood malnutrition on later health outcomes, including coronary heart disease and diabetes. She emphasizes the importance of physical activity, strength training, and the need for inclusive research to address health disparities. Future research directions include understanding cognitive impairment related to diabetes and developing effective interventions for diverse populations. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 39392]
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  Reversal of Disease using a Whole-Food Plant-Based Diet 26.02.2024 12min

  Anthony Lim, M.D., J.D. shares research that tackles diseases through a whole-food, plant-based diet. Learn how food choices can transform your well-being. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 39600]
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  Beta Adrenergic Receptors and Their Role in Heart Function 29.09.2023 56min

  Learn about groundbreaking research being conducted by some of the most highly skilled and intelligent minds in the nation towards enhancing human health, in fields such as biomedical sciences, social sciences, and digital health. This program will talk about beta adrenergic receptors, which are key components of the body's cardiovascular system, playing a vital role in modulating heart rate, contractility, and blood vessel activity in response to various physiological and environmental stimuli. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 38983]
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  Stem Cells and Clinical Genomics for Clinical Trials in Dish - Breaking News in Stem Cells 15.09.2023 52min

  Joseph C. Wu, M.D., Ph.D., shares his pioneering research on cardiovascular disease mechanisms using patient-specific stem cells. Learn about accelerated drug discovery, "clinical trials in a dish," and precision medicine's impact on treatment. Explore genomics, stem cells, imaging, and more. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 38327]
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  How To Manage High Blood Cholesterol 01.07.2023 1t 25min

  Having a skilled primary care clinician will go a long way to maintaining your health and wellness. In this program on primary care basics, Dr. Robert B. Baron discusses the best practices for managing blood cholesterol and understanding the benefits and harms to prevent heart attacks and strokes. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 38794]
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  How To Manage High Blood Pressure 10.06.2023 1t 29min

  Having a skilled primary care clinician will go a long way to maintaining your health and wellness. In this program on primary care basic, Dr. Robert B. Baron discusses the best practices in how to measure blood pressure, treatment goals, diet, lifestyle and medications. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 38791]
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  Donation after Circulatory Determination of Death in Heart Transplantation 09.03.2023 56min

  Hundreds of thousands of people in the U.S. are receiving treatment for failing kidneys, livers, hearts, and other organs. Learn about the current strategies and new advances to support, provide organs and solutions to those in need. In this program, Dr. Jason Smith discusses the process for determining when to perform a heart transplant after death. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 38490]
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  Heart Valves: What Can Go Wrong and the Latest Approaches to Making Them Right Again 25.02.2023 57min

  What role do genetics, diet, exercise and cholesterol play in preventing and treating diseases of the heart? Learn about advances in the prevention and treatment of heart disease, coronary artery disease and heart attacks, abnormal rhythms such as atrial fibrillation, cardiac arrest, the failing heart, and diseases of the heart valves. In this UCSF program, Dr. Sammy Elmariah and Dr. Tom C. Nguyen explain what can go wrong with valves of the heart and how to correct them. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 38486]
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  Heart Attacks Angioplasties and Stents Oh My! 04.02.2023 1t 22min

  What role do genetics, diet, exercise and cholesterol play in preventing and treating diseases of the heart? Learn about advances in the prevention and treatment of heart disease, coronary artery disease and heart attacks, abnormal rhythms such as atrial fibrillation, cardiac arrest, the failing heart, and diseases of the heart valves. In this program, Dr. Krishan Soni discusses interventions such as angioplasties and stents to treat heart attacks. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 38484]
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  Heart Failure: What it Means and the Many Effective Treatments Now Available 21.01.2023 58min

  What role do genetics, diet, exercise and cholesterol play in preventing and treating diseases of the heart? And what is heart failure? In this UCSF program, Dr. Liviu Klein explains why heart failure is a complex clinical syndrome, and how to treat the condition. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 38485]
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  Implantable Devices to Diagnose and Treat Cardiac Rhythm Disorders 20.01.2023 1t 27min

  What role do genetics, diet, exercise and cholesterol play in preventing and treating diseases of the heart? Learn about advances in the prevention and treatment of heart disease, coronary artery disease and heart attacks, abnormal rhythms such as atrial fibrillation, cardiac arrest, the failing heart, and diseases of the heart valves with Dr. Thomas Dewland, who talks about implantable devices like pacemakers and defibrillators. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 38483]
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  Atrial Fibrillation: Alcohol Caffeine Apple Watches and What They All Have To Do With the Most Common Heart Rhythm Disturbance 03.12.2022 1t 29min

  What role do genetics, diet, exercise and cholesterol play in preventing and treating diseases of the heart? Learn about advances in the prevention and treatment of heart disease, including an overview of abnormal rhythms such as atrial fibrillation and diet with Dr. Gregory Marcus. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 38481]
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  Prevention of Heart Disease: What You and Your Doctor Can Do to Minimize Risk 01.12.2022 1t 21min

  What role do genetics, diet, exercise and cholesterol play in preventing and treating diseases of the heart? Learn about advances in the prevention and treatment of heart disease, and what you and your doctor can do to minimize risk with Dr. Carlin Long. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 38482]
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  With Heart For Hearts – A Decade of Excellence at Sulpizio Cardiovascular Center - Health Talks 05.08.2021 59min

  Sulpizio Cardiovascular Center at UC San Diego Health marks 10 years of care. Explore patients’ experiences and the center’s impact on the community. From transforming cardiovascular medicine in San Diego to new collaborations, the last decade has led to tremendous success for cardiovascular medicine including the establishment of the Cardiovascular Institute. Series: "UC San Diego Health Talks" [Health and Medicine] [Show ID: 37275]