Mayo Clinic Talks

Episode

• Addiction Care & Empowering the Non-Specialist 02.06.2026 28mnt

  Host: Darryl S. Chutka, M.D.  Guest: Benjamin Lai, M.D.  Substance use disorders are chronic and often relapsing conditions associated with compulsive substance use. They result from a complex interaction of chemistry within the brain, often combined with genetic and environmental issues. Common substances involve alcohol, stimulants, sedatives and opioids; opioids commonly prescribed by health care clinicians. Early identification of patients and care coordinated with behavioral health specialists is the best approach to improved patient outcomes. The topic for this podcast is “Addiction Care and Empowering Non-Specialists”, and my guest is Dr. Benjamin Lai, A Family Medicine physician from the Department of Family Medicine at the Mayo Clinic.  Connect with us! Mayo Clinic Talks Podcast Season 6 | Mayo Clinic School of Continuous Professional Development 
• Fibromyalgia 26.05.2026 33mnt

  Host: Darryl S. Chutka, M.D.  Guest: Michael Mueller, M.D.  Fibromyalgia is a chronic health problem commonly seen in a primary care setting. It can be challenging to diagnose and even more so to manage. It can have a devastating effect on a patient’s lifestyle, and patients will commonly go from provider to provider seeking relief for their chronic symptoms. We now have a better understanding of the pathophysiology of fibromyalgia; unfortunately, the treatment remains less than optimal. What do we know regarding the cause of the symptoms in fibromyalgia? How can we efficiently establish a diagnosis in patients with the condition without excessive testing? How do we explain the disorder to patients and what’s the long-term outlook for patients? These are some of the questions I’ll be asking my guest, Dr. Michael Mueller, an internist in the Division of General Internal Medicine at the Mayo Clinic as we discuss “Fibromyalgia”.  Connect with us! Mayo Clinic Talks Podcast Season 6 | Mayo Clinic School of Continuous Professional Development 
• Bladder Cancer 21.05.2026 28mnt

  Host: Darryl S. Chutka, M.D  Guest: Mark D. Tyson, III, M.D., M.P.H.  Bladder cancer is one of the most common malignancies worldwide, and primary care clinicians are often the first to evaluate patients with bladder cancer. The symptoms are usually subtle and may include either gross or microscopic hematuria. The decision in whether to investigate these presenting symptoms can often impact early diagnosis and the patient’s outcome. When should we investigate hematuria? What should an evaluation of hematuria consist of? What is the treatment for bladder cancer? How should patients with recurrent bladder cancer be managed? What role does the primary care clinician play in the long-term management of patients? I’ll be asking these questions and more of my guest, Dr. Mark Tyson, a urologist at the Mayo Clinic as we discuss “Bladder Cancer”.  Connect with us! Mayo Clinic Talks Podcast Season 6 | Mayo Clinic School of Continuous Professional Development 
• Hantavirus 19.05.2026 23mnt

  Host: Darryl S. Chutka, M.D.  Guest: Stacey Rizza, M.D.  Hantavirus has been in the news lately. Although it’s rare, it can cause serious disease which can be life-threatening.  Early symptoms are similar to other common viral infections including fever, myalgias, headache, and fatigue. As a result, the ability to establish an early diagnosis is challenging. Who’s at risk of acquiring Hantavirus? Does it have the potential to become our next pandemic? How likely is human-to-human transmission? Is there any effective treatment and what preventive measures should one take to minimize the acquisition of the disease? I’ll get answers to these questions in this podcast as we discuss Hantavirus. My guest is an infectious disease specialist, Dr. Stacey Rizza from the Mayo Clinic.  Connect with us! Mayo Clinic Talks Podcast Season 6 | Mayo Clinic School of Continuous Professional Development 
• Update on Celiac Disease 12.05.2026 30mnt

  Host: Darryl S. Chutka, M.D.   Guest: Joseph Murray, M.D.  Celiac Disease affects approximately 1% of the population worldwide and can present at any age, frequently with very subtle, atypical or at times entirely non-GI symptoms. The presentation can be extremely diverse and may involve a variety of organ systems. If not recognized and effectively treated, multiple potentially serious complications can develop. Primary care clinicians are often the initial point of contact, and we need to know the common presenting symptoms, which tests should be ordered when we suspect the disease and when a referral is necessary. We also play a role in long-term management by monitoring for nutritional deficiencies, bone integrity, and the patient’s adherence to a gluten-free diet. In this podcast, we’ll explore Celiac Disease with my guest, Dr. Joseph Murray, a gastroenterologist from the Mayo Clinic, and a nationally recognized specialist in Celiac Disease. We’ll focus on practical information you can apply to your practice.  Connect with us! Mayo Clinic Talks Podcast Season 6 | Mayo Clinic School of Continuous Professional Development 
• Lupus Today: Advances in Diagnosis and Treatment 05.05.2026 30mnt

  Host: Darryl S. Chutka, M.D.  Guest: Uma Thanarajasingham, M.D., Ph.D.  Systemic lupus is a chronic autoimmune disease with a variety of immunologic and laboratory abnormalities. It has numerous clinical manifestations potentially involving multiple organs. It’s known as the great imitator because it can mimic a variety of other diseases, and it’s not uncommon for patients to have symptoms for a number of years prior to a diagnosis being established. What symptoms should alert us to the possibility of lupus? What do we do with a low titer, positive ANA? How is a firm diagnosis established and what role does the primary care clinician play in the management of those with lupus? I’ll be asking these questions and more of my guest, Dr. Uma Thanarajasingam from the Division of Rheumatology at the Mayo Clinic as we discuss “Lupus Today: Advances in Diagnosis and Treatment”.  Connect with us! Mayo Clinic Talks Podcast Season 6 | Mayo Clinic School of Continuous Professional Development 
• Pediatric Transplant: Kidney 28.04.2026 29mnt

  Host: Darryl S. Chutka, M.D.  Guest: Carl H. Cramer, III, M.D.  Kidney transplantation has significantly improved the outlook for children with end-stage renal failure. The journey these children follow to transplantation starts in primary care with the recognition of chronic kidney disease, timely referral to nephrology, and long-term coordination of care with the transplant team. What are the most common health conditions which result in chronic kidney disease in children? What are some of the challenges faced in pediatric kidney transplantation and what do primary care clinicians need to know in caring for these children following kidney transplant? These are some of the questions I’ll be asking my guest Dr. Carl Cramer, a pediatric nephrologist and specialist in pediatric renal transplantation at the Mayo Clinic as we discuss “Pediatric Kidney Transplant”.  Mayo Clinic Talks: Transplantation Series  Connect with us! Mayo Clinic Talks Podcast Season 6 | Mayo Clinic School of Continuous Professional Development 
• Pediatric Transplant: Heart 23.04.2026 26mnt

  Host: Darryl S. Chutka, M.D.  Guest: Rebecca Ameduri, M.D.  Most primary care clinicians see very few children with advanced heart failure or complicated congenital heart disease. However, when they are a part of our practice, they require timely referral and coordination with other medical specialties, as well as ongoing longitudinal and supportive care not only for the patient but also for their family. A heart transplant is a lifesaving and life-changing procedure for these patients. As the survival of these children improves, more transplant recipients are living into adulthood. For primary care clinicians, what are some early “red flag” symptoms that should raise our suspicion for cardiac failure? What tests should we order and when is the best time for a child to be referred for consideration for a heart transplant? The topic for this podcast is “Pediatric Heart Transplant” and we’ll tackle these issues and more. My guest is Dr. Rebecca Ameduri, a pediatric cardiologist with special expertise in pediatric heart transplantation.  Mayo Clinic Talks: Transplantation Series  Connect with us! Mayo Clinic Talks Podcast Season 6 | Mayo Clinic School of Continuous Professional Development 
• Deep Brain Stimulation for Parkinson’s Disease 21.04.2026 28mnt

  Host: Darryl S. Chutka, M.D.  Guest: Lauren Jackson, M.D.  Deep brain stimulation is an established management option for Parkinson’s Disease. It’s a neurosurgical procedure in which thin electrodes are implanted into various areas of the brain and then connected to a pulse generator that produces electrical stimulation which modulates abnormal brain activity. The procedure has the potential to improve the quality of life in those with Parkinson’s by reducing motor symptoms including tremor, rigidity and bradykinesia. It also enables a reduction in doses of dopaminergic medications. Who’s a candidate for this procedure? Is there an optimal time in the course of the disease to perform it? What can patients expect in terms of symptom improvement? How long do patients see benefits? These are some of the questions I’ll be asking my guest, Dr. Lauren Jackson, a neurologist from the Department of Neurology at the Mayo Clinic. The topic for this podcast is “Deep Brain Stimulation for Parkinson’s Disease”.  Connect with us! Mayo Clinic Talks Podcast Season 6 | Mayo Clinic School of Continuous Professional Development 
• Advancements in the Diagnosis and Treatment of Parkinson’s Disease 16.04.2026 27mnt

  Host: Darryl S. Chutka, M.D.  Guest: Forrest Sturgill, M.D.  Parkinson’s Disease is a relatively common neurodegenerative disorder characterized by motor symptoms such as bradykinesia, rigidity and resting tremor, as well as non-motor symptoms such as autonomic dysfunction, mood disorders and cognitive changes. The diagnosis is established with a medical history and physical exam. Parkinson’s is truly a disorder where the neurologist needs to work with the primary care clinician to provide optimal care of the patient. What are the typical presenting symptoms of Parkinson’s? Is an urgent referral to a neurologist necessary? When should pharmacologic treatment be started? The topic for this podcast is “Advancements in the Diagnosis and Treatment of Parkinson’s Disease” and these are some of the questions I’ll be asking my guest, Dr. Forrest Sturgill, a neurologist in the Department of Neurology at the Mayo Clinic.    Connect with us! Mayo Clinic Talks Podcast Season 6 | Mayo Clinic School of Continuous Professional Development 
• Parkinson’s Disease in Children and Young Adults 14.04.2026 30mnt

  Host: Darryl S. Chutka, M.D.  Guest: Rodolfo Savica, M.D., Ph.D.  We commonly see Parkinson’s Disease in our older patients, but have you ever seen it present in a child or young adult? It can happen. Whereas Parkinson’s Disease in an older patient is likely to be idiopathic, we need to consider genetic conditions as well as secondary causes when it occurs in younger individuals. It’s important for primary care clinicians to recognize young patients with symptoms of Parkinson’s in order to rule out other potentially treatable conditions. Does Parkinson’s present any differently in children or young adults? How fast does it typically progress? Is the management of a child or young adult different? These are some of the questions I’ll be asking my guest, Dr. Rodolfo Savica a neurologist from the Department of Neurology at the Mayo Clinic as we discuss “Parkinson’s Disease in Children and Young Adults”.  Connect with us! Mayo Clinic Talks Podcast Season 6 | Mayo Clinic School of Continuous Professional Development 
• Mayo Clinic Proceedings: Diabetes and Novel Therapies for Diabetes 09.04.2026 33mnt

  Host: Darryl S. Chutka, M.D.  Guest: Vinaya Simha, M.B.B.S., M.D.  For years, we saw very little change in the management of type 2 diabetes. However, over the past decade, numerous new pharmacologic treatment options, innovations in glucose monitoring, and new insulin delivery systems have become available. We’ve also seen a new philosophy regarding the goals of diabetes management. What are the latest medications for diabetes and is there still a role for the older, traditional options? How have the improvements in technology affected the management of diabetes and what are the newly established goals for managing patients with the disease? These are some of the questions I’ll be asking my guest, Dr. Vinaya Simhah from the Division of Endocrinology, Diabetes and Metabolism at the Mayo Clinic as we discuss “Diabetes and Novel Therapies for Diabetes”.  This episode of Mayo Clinic Talks is the third of three podcasts celebrating a remarkable milestone in Mayo Clinic’s history – the 100th anniversary in April this year of our renowned journal, Mayo Clinic Proceedings. Proceedings first appeared in April 1926 and has been in continuous publication ever since. Many significant clinical breakthroughs, pioneered at Mayo Clinic, were first published in the journal, and today the journal brings primary care providers relevant, timely, and important papers on conditions and disorders that are frequently seen in the practice. A great deal of content in Mayo Clinic Proceedings is freely available for you to browse—just go to https://www.mayoclinicproceedings.org to incorporate this terrific resource in your library. Connect with us! Mayo Clinic Talks Podcast Season 6 | Mayo Clinic School of Continuous Professional Development 
• Mayo Clinic Proceedings: Healthy Aging 07.04.2026 28mnt

  Host: Darryl S. Chutka, M.D.  Guest: Robert Pignolo, M.D., Ph.D.  Our population is aging as our life expectancy increases with time. In general, we’re living longer than those before us. Aging is an interesting concept; we all want to achieve old age, but it’s not something we look forward to. What we really want is to maintain our physical, mental and social well-being in order to achieve a high quality of life as we age. I’m talking about healthy aging and that’s the topic of this podcast. What degree of healthy aging is due to genetic factors vs. intentional choices we make during our life? Which lifestyle behaviors are most important in achieving healthy aging, and what can we learn from those who have lived exceptionally long lives? These are some of the questions I’ll be asking my guest, Dr. Robert Pignolo, an internist and named professor of geriatric medicine in the Center of Aging at the Mayo Clinic.  This episode of Mayo Clinic Talks is the second of three podcasts celebrating a remarkable milestone in Mayo Clinic’s history – the 100th anniversary in April this year of our renowned journal, Mayo Clinic Proceedings. Proceedings first appeared in April 1926 and has been in continuous publication ever since. Many significant clinical breakthroughs, pioneered at Mayo Clinic, were first published in the journal, and today the journal brings primary care providers relevant, timely, and important papers on conditions and disorders that are frequently seen in the practice. A great deal of content in Mayo Clinic Proceedings is freely available for you to browse—just go to https://www.mayoclinicproceedings.org to incorporate this terrific resource in your library. Connect with us! Mayo Clinic Talks Podcast Season 6 | Mayo Clinic School of Continuous Professional Development 
• Mayo Clinic Proceedings: Sleep Disorders and How They Adversely Affect Health 02.04.2026 31mnt

  Host: Darryl S. Chutka, M.D.  Guest: Bhanu Kolla, M.D.  We commonly take sleep for granted. That is, until our sleep quantity or quality is compromised. This can result in both mental and physical health problems, including daytime fatigue and sleepiness. Sleep disorders are quite common and often undiagnosed, yet they can contribute to diabetes, cognitive impairment, and cardiovascular disease, potentially leading to premature mortality. Primary care clinicians play a major role in the identification and management of sleep disorders. What are the most common disorders we see in the outpatient setting? What are the presenting symptoms we should watch for? What tests should we do to establish a diagnosis and when should we refer patients we feel may have a sleep disorder? The topic for today’s podcast is sleep disorders, and these are questions I’ll be asking my guest, Dr. Bhanu Kolla, a psychiatrist and sleep medicine specialist from the Center for Sleep Medicine at the Mayo Clinic.   This episode of Mayo Clinic Talks is the first of three podcasts celebrating a remarkable milestone in Mayo Clinic’s history – the 100th anniversary in April this year of our renowned journal, Mayo Clinic Proceedings. Proceedings first appeared in April 1926 and has been in continuous publication ever since. Many significant clinical breakthroughs, pioneered at Mayo Clinic, were first published in the journal, and today the journal brings primary care providers relevant, timely, and important papers on conditions and disorders that are frequently seen in the practice. A great deal of content in Mayo Clinic Proceedings is freely available for you to browse—just go to mayoclinicproceedings.org to incorporate this terrific resource in your library. Connect with us! Mayo Clinic Talks Podcast Season 6 | Mayo Clinic School of Continuous Professional Development 
• Retinal Disorders 31.03.2026 32mnt

  Host: Darryl S. Chutka, M.D.  Guest: Brittni A. Scruggs, M.D., Ph.D.  There are a variety of eye disorders which involve the retina, and they all have the potential to cause significant vision loss or blindness if not detected early. Two of the most common retinal disorders we see in primary care include diabetic retinopathy and macular degeneration. Since most health conditions affecting the retina are asymptomatic early in their course making patient screening and risk factor management an important task for primary care clinicians. Appropriate referrals to an ophthalmologist can result in effective treatment and improved outcomes. Which patients are at risk of retinal disorders? What are some “red flag” symptoms which should give us concern? Which medications we prescribe can affect the retina? This podcast is about retinal disorders, and I’ll be asking these questions and more of my guest, Dr. Brittni Scruggs, an ophthalmologist and retinal surgeon at the Mayo Clinic.  Connect with us! Mayo Clinic Talks Podcast Season 6 | Mayo Clinic School of Continuous Professional Development 
• Update in the Management of Hyperlipidemia 24.03.2026 28mnt

  Host: Darryl S. Chutka, M.D.  Guest: Stephen Kopecky, M.D.  Cardiovascular disease is highly prevalent in our society. Fortunately, we have a variety of treatment options to lower the risk of developing its complications. Over the past decade, there’ve been many changes in managing hyperlipidemia, one of the most important risk factors for cardiovascular disease. This includes a change in assessing our patients’ risk, identification of new risk factors, new testing options, and new pharmacologic options for treating hyperlipidemia. We’ll cover all of these topics in this podcast. My guest is Dr. Stephen Kopecky, a preventive cardiologist at the Mayo Clinic, and we’ll be discussing “Update in the Management of Hyperlipidemia”.  Connect with us! Mayo Clinic Talks Podcast Season 6 | Mayo Clinic School of Continuous Professional Development 
• Pulmonary Vascular Complications of Liver Disease 17.03.2026 24mnt

  Host: Darryl S. Chutka, M.D.  Guest: Kathryn del Valle, M.D.  Chronic liver disease can result in a variety of complications which can involve multiple organs. One of these complications can occur in the pulmonary vascular system. Two of the most clinically significant include hepatopulmonary syndrome and Portopulmonary hypertension. Patients with these syndromes may present to their primary care provider and if the medical condition is unrecognized, it can affect morbidity and ultimately the prognosis of the patient. What are the early symptoms and physical findings of hepatopulmonary syndrome and Portopulmonary hypertension? How are they diagnosed, and should we be screening patients with chronic liver disease for these pulmonary vascular disorders? My guest for this podcast is Dr. Kathryn del Valle, from the Division of Pulmonary and Critical Care at the Mayo Clinic and we’ll be discussing “Pulmonary Vascular Complications of Liver Disease”.  Connect with us! Mayo Clinic Talks Podcast Season 6 | Mayo Clinic School of Continuous Professional Development 
• Non-Hodgkin's Lymphoma 12.03.2026 20mnt

  Host: Darryl S. Chutka, M.D.  Guest: Stephen Ansell, M.D., Ph.D.  Non-Hodgkin’s Lymphoma is a group of hematologic malignancies originating in the lymphatic system. There are over 60 subtypes of lymphoma with varying degrees of aggressiveness. It can present with a variety of rather subtle symptoms, often making the diagnosis challenging. Although Non-Hodgkin’s Lymphoma is typically managed by a hematologist or oncologist, the primary care provider plays a role in its recognition, preliminary diagnostic tests and supporting patients through their treatment. What are some of the more common symptoms and signs of Non-Hodgkin’s Lymphoma? Which ones should prompt an urgent referral, and what preliminary tests should we do prior to referring the patient? These are some of the questions I’ll be asking my guest, Dr. Stephen Ansell, Chair of the Division of Hematology at the Mayo Clinic. The topic for this podcast is Non-Hodgkin’s Lymphoma.  Connect with us! Mayo Clinic Talks Podcast Season 6 | Mayo Clinic School of Continuous Professional Development 
• Hodgkin's Lymphoma 10.03.2026 24mnt

  Host: Darryl S. Chutka, M.D.  Guest: Stephen Ansell, M.D., Ph.D.  Hodgkin’s Lymphoma is an uncommon but very curable malignancy involving the lymphatic system. It most commonly presents in young adults as well as middle-aged and older individuals. Although Hodgkin’s is generally managed by hematologists or oncologists, the primary care provider plays a major role in its recognition, hopefully leading to a timely diagnosis and eventual staging. What are some early signs of Hodgkin’s and what preliminary work-up should we do prior to referring the patient for definitive care? How do we monitor those who have had successful treatment of Hodgkin’s? These are some of the questions I’ll be asking my guest, Dr. Stephen Ansell, Chair of the Division of Hematology at the Mayo Clinic as we discuss Hodgkin’s Lymphoma.  Connect with us! Mayo Clinic Talks Podcast Season 6 | Mayo Clinic School of Continuous Professional Development 
• Heart Health Series | Diastolic Heart Failure 03.03.2026 29mnt

  Host: Darryl S. Chutka, M.D.  Guests: Jae K. Oh, M.D., Tahir S. Kafil, M.D.  Diastolic heart failure is also known as heart failure with preserved ejection fraction. Although we don’t hear the term all that often, it actually represents a fairly large percentage of all cases of heart failure. Some studies suggest it represents the majority of heart failure cases. Older adults are most commonly affected with symptoms similar to those of systolic heart failure. So how do we suspect diastolic heart failure? How should the diagnosis be established, and how does the treatment differ from systolic heart failure? Finally, what role do primary care providers play in the management of the condition? These are some of the questions I’ll be asking my guests, Dr. Jae Oh and Dr. Tahir Kafil, both cardiologists in the Department of Cardiovascular Disease at the Mayo Clinic as we discuss “Diastolic Heart Failure”.   Mayo Clinic Talks: Heart Health | Mayo Clinic School of Continuous Professional Development  Connect with us! Mayo Clinic Talks Podcast Season 6 | Mayo Clinic School of Continuous Professional Development