unPAUSED with Dr. Mary Claire Haver

unPAUSED with Dr. Mary Claire Haver

Audacy | Mary Claire Haver, MD
USA
ジャンル Society & Culture, Health & Fitness, Medicine
言語 EN
エピソード数 40
最新 26.05.2026

Welcome to unPAUSED, the podcast where bold, unfiltered conversations take place about what it really takes for women to thrive in the second half of life. Every week, Dr. Mary Claire Haver, a board-certified Obstetrician-Gynecologist, Certified Menopause Practitioner, and #1 New York Times best-selling author, tackles the conversations women actually need to hear. Dr. Haver sits down with a variety of medical experts, CEOs, and risk-takers to discuss everything that matters, from hormones and identity to financial power, relationships, and the tools needed to build the life you want. unPAUSED is about reclaiming your healthspan—not just the number of years you live, but the number of years you live well. Tune in every Tuesday for new episodes of unPAUSED. Subscribe now so you don't miss it.

エピソード

  • GLP-1s, Hormones, and Why You Can't Calorie-Count Your Way Out of Menopause with Dr. Michelle Gordon 02.06.2026 1時間 15分
    In this episode of unPAUSED, Dr. Mary Claire Haver sits down with Dr. Michelle Gordon, a board certified obesity medicine physician and diplomate of the American College of Lifestyle Medicine, with surgical fellowships from the American College of Surgeons and the American College of Osteopathic Surgeons. Through her practice Thrive Span Medical, she works with midlife women across 39 states whose metabolic and hormonal symptoms have been dismissed as normal aging. Dr. Gordon opens by dismantling the calories in, calories out framework, not as a vague wellness talking point but on a physiological level. She explains why biology determines the burn rate, why fat oxidation drops by 32% in perimenopause, why visceral fat accumulation accelerates when estrogen declines, and why insulin resistance and leptin resistance make it nearly impossible for midlife women to lose weight through willpower alone. She also covers how sleep deprivation compounds all of it, creating a cycle of cravings, brain fog, and weight gain that most women are navigating without any clinical support. Guest links: Michelle E. Gordon, DO (LinkedIn) Dr. Michelle Gordon (Instagram) Dr. Gordon, Obesity Medicine (Substack) Dr. Michelle Gordon (Facebook) Dr. Michelle Gordon Dr. Michelle Gordon (TikTok) Dr. Michelle Gordon Dr. Michelle Gordon (YouTube) Books: “The New Perimenopause: An Evidence-Based Guide to Surviving the Zone of Chaos and Feeling Like Yourself Again,” by Dr. Mary Claire Haver “The New Menopause,” by Dr. Mary Claire HaverWeightless: A Doctor's Guide to GLP-1 Medications, Sustainable Weight Loss, and the Health You Deserve,” by Dr. Rocio Salas-Whalen For full show notes, please click here. To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices
  • Menopause Is a Portal: Reclaiming the Body, the Story, and the Second Half with Dr. Hillary McBride 26.05.2026 1時間 11分
    In this episode of unPAUSED, Dr. Mary Claire Haver sits down with Dr. Hillary McBride, a psychologist, researcher, and author whose work focuses on women's lived experience of embodiment across the lifespan, and particularly what happens during the perimenopausal and menopausal transition. She brings a feminist, biopsychosocial lens to the work, looking at the intersection of biology and culture and how the stories we are handed about aging as women can shape what we actually feel, right down to measurable health outcomes. Dr. McBride opens by naming what the research literature has gotten wrong. Women's voices have been largely absent from the empirical conversation about perimenopause and menopause, and what women are actually saying when asked about their experience is strikingly different from what the medical literature reflects. They are describing not just difficulty but clarity, not just loss but a deepening sense of self, not just symptoms but a portal. Guest links: Hillary L. McBride  Hillary L. McBride (Instagram) Hillary McBride (Facebook) Hillary McBride (X) Books: Hillary L. McBride For full show notes, please click here. To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices
  • The Holistic Plastic Surgeon: Devices, Ozempic Face, and What Your Habits Do to Aging Skin 21.05.2026 42分
    In this episode of unPAUSED, Dr. Mary Claire Haver continues her conversation with Dr. Tony Youn, board certified plastic surgeon, bestselling author of Younger for Life, and the most followed plastic surgeon on social media. In part two of this conversation, Dr. Youn moves from skincare into devices, lifestyle, and the bigger picture of how women can think about aging and anti-aging without getting swept up in the extremes. Dr. Youn walks through the most commonly asked about in-office treatments, explaining what each one actually does and where the limitations are. He covers IPL for hyperpigmentation and sun damage, fractional CO2 lasers and how they differ from older more aggressive approaches, chemical peels and how depth determines results, and radiofrequency microneedling including what it can realistically achieve and where it falls short. He also addresses at-home devices, covering red light therapy and what the studies actually show about collagen and elastin, and what to look for in a dermal stamper. Guest links: Anthony Youn, MD Tony Youn, MD (Instagram) Doctor Youn (TikTok) Dr. Anthony Youn (Facebook) Doctor Youn (YouTube) The Doctor Youn Show (Apple Podcasts) Books “The New Perimenopause,” by Dr. Mary Claire Haver “The New Menopause"⁠ by Dr. Mary Claire Haver“Younger for Life: Unlocking the Secrets of Longevity, Nutrition and Self-Care for a Youthful Life,” by Anthony Youn ⁠"Playing God"⁠ by Anthony Youn ⁠"The Age Fix" ⁠by Anthony Youn ⁠"In Stitches"⁠ by Anthony Youn For full show notes, please click here. To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices
  • What Estrogen Does to Your Skin (And What Actually Works) 19.05.2026 1時間 6分
    In this episode of unPAUSED, Dr. Mary Claire Haver sits down with Dr. Tony Youn, a board certified plastic surgeon nationally recognized as one of the top plastic surgeons in the United States, bestselling author of Younger for Life, and the most followed plastic surgeon on social media with more than five million YouTube subscribers and eight million TikTok followers. In part one of this two part conversation, they take on a question that sits at the intersection of hormones and skin health that most doctors have never connected for their patients: what estrogen is actually doing to the skin, and what women can do about it. Dr. Youn opens with a statistic that women lose 30% of the thickness of their collagen in the first five years after menopause, and then continue losing collagen at twice the rate of men for every year that follows. He explains exactly why this happens, how estrogen interacts with the fibroblasts that produce collagen and elastin, what declining estrogen does to hyaluronic acid and skin hydration, and why women are not imagining it when their skincare suddenly stops working. Guest links: Anthony Youn, MD Tony Youn, MD (Instagram) Doctor Youn (TikTok) Dr. Anthony Youn (Facebook) Doctor Youn (YouTube) The Doctor Youn Show (Apple Podcasts) Books “The New Perimenopause,” by Dr. Mary Claire Haver “The New Menopause"⁠ by Dr. Mary Claire Haver“Younger for Life: Unlocking the Secrets of Longevity, Nutrition and Self-Care for a Youthful Life,” by Anthony Youn "Playing God" by Anthony Youn "The Age Fix" by Anthony Youn "In Stitches" by Anthony Youn To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices
  • Menopause Masterclass: HRT Safety, Patch Absorption, Progesterone Intolerance, and Bone Density 12.05.2026 1時間 4分
    In this episode of unPAUSED, Dr. Mary Claire Haver answers your most asked questions about hormone therapy, menopause symptoms, and how to advocate for yourself when your doctor doesn't have answers. She walks through who actually qualifies for HRT, what the real contraindications are versus conditions that simply require a different delivery method, and how to think about continuing estrogen, progesterone, and testosterone therapy after 60. Dr. Haver explains the estrogen patch absorption problem, with research showing that up to 20 percent of women on transdermal therapy never reach physiologic estradiol levels regardless of dose. She breaks down SHBG, the protein that can bind your hormones and render them inactive even when your numbers look adequate on paper, and walks through what optimal estradiol levels look like for bone density and osteoporosis prevention specifically. Books: “The Complete Bone and Joint Health Plan: Help Prevent and Treat Osteoporosis and Arthritis,” by Jocelyn Wittstein“The New Perimenopause,” by Dr. Mary Claire Haver Resources: Women’s Health Initiative Estradiol (University of Rochester Medical Center) Meet Dr. Heather Hirsch Alloy Health Midi Health Menopause Quiz Lab Test Checklist Blueprint to close the women's health gap For full show notes, please click here. To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices
  • Mast Cells, Histamine, and Perimenopause Explained: MCAS, Anxiety, Estrogen 09.05.2026 46分
    In this bonus episode of unPAUSED, Dr. Mary Claire Haver is joined by Dr. Zachary Rubin, double board certified allergist and immunologist and New York Times bestselling author of All About Allergies, to dig into the connection between histamine, mast cells, and women's hormonal health. Dr. Rubin breaks down what mast cells are, how histamine works across multiple organ systems, and why women are disproportionately affected by mast cell related conditions including mast cell activation syndrome (MCAS). The two dig into the estrogen and histamine connection, why perimenopause can trigger or worsen symptoms like anxiety, brain fog, and histamine intolerance, and what MCAS actually is and how it is diagnosed. Dr. Rubin also addresses the viral H1 and H2 blocker combination that has been circulating online, explaining the real science behind why it may be helping some women with PMDD, endometriosis, and perimenopausal symptoms, while being honest about what we still do not know. They also cover quercetin, DAO supplements, low histamine diets, and how to think about self experimentation safely. If you have been wondering whether histamine could be a piece of your hormonal health puzzle, this conversation is a great place to start. To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices
  • Estrogen, Progesterone, and Testosterone: The Science of Hormones, Sexual Function, and Menopause 05.05.2026 1時間 24分
    In this episode of unPAUSED, Dr. Mary Claire Haver sits down with Dr. Tami Rowen, an obstetrician, gynecologist, and leading gynecologic surgeon at the University of California San Francisco, and an internationally recognized expert in sexual health and sexual medicine. Together they get precise about some of the most misunderstood terrain in women's health: estrogen, progesterone, progestins, and testosterone for women, what they actually do in the body, how the confusion around them began, and what becomes possible for women when care is evidence-based and not fear-based. Dr. Rowen opens with something most women have never been told: that contraceptive estrogen and menopausal estrogen are fundamentally different molecules with different goals, different mechanisms, and different effects on the body. She walks through why ethinyl estradiol, the synthetic estrogen in most birth control pills, binds to the estrogen receptor 300 times more strongly than natural estradiol, why that matters for everything from blood clotting to testosterone levels to bone density, and why modern contraception is still valuable and worth defending even as we get more precise about how it works. Guest links: Dr. Tami Rowen (UCSF Health) Dr. Tami Rowen (ISSWSH)Dr. Tami Rowen (Instagram) To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices
  • The Holderness Family Gets Real About Perimenopause 28.04.2026 1時間 3分
    In this episode of unPAUSED, Dr. Mary Claire Haver sits down with Kim and Penn Holderness, the husband and wife content creators behind the widely popular Holderness Family, bestselling authors, and winners of The Amazing Race Season 33. Together they built an audience of millions by finding the humor in real life, and in this conversation they turn that same lens on perimenopause, ADHD, marriage, and the particular chaos of midlife. Kim opens up about the perimenopausal symptoms that arrived before she had any name for them: the anxiety that made everything feel like being chased by a bear, the panic attacks triggered by nothing she could identify, and the growing sense that something was fundamentally wrong with her. She describes walking out of her doctor's office with no treatment after being told her symptoms were normal, the financial reality of having to seek out a functional medicine doctor to finally get the estrogen and progesterone support she needed, and the combination of hormonal and psychiatric care that eventually helped her feel like herself again. She also speaks with real honesty about her postpartum anxiety, perimenopause and depression, and her OCD diagnosis, and how all of it left her desperate for a voice that would simply say: this is hard. Guest links: The Holderness Family  The Holderness Family (Instagram) The Holderness Family - Music (YouTube) The Holderness Family - Comedy (YouTube) The Holderness Family (Facebook) The Holderness Family (Substack) The Holderness Family (TikTok) Laugh Lines with Kim & Penn Holderness (Apple Podcasts) PC’s Playbook Podcast (YouTube) Books: “ADHD Is Awesome,” by Penn and Kim Holderness “Everybody Fights,” by Penn and Kim Holderness To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices
  • The Testosterone Conversation with Dr. Kelly Casperson: Beyond Libido 23.04.2026 1時間 14分
    In this episode of unPAUSED, Dr. Mary Claire Haver continues her conversation with Dr. Kelly Casperson, urologist, author, and host of the podcast "You Are Not Broken." Part 2 goes deep on testosterone therapy for women, the most misunderstood hormone in women's health, and covers the full range of what it actually does in the female body, why every woman will experience declining levels over time, and why there are still zero FDA approved testosterone products for women while men have more than a dozen. Dr. Casperson opens with the basics: ovaries make testosterone, the hormone pathway runs one way from cholesterol through progesterone to testosterone to estradiol, and women in normal cycling years carry four times more testosterone than estrogen in their bodies. She explains where testosterone receptors are found, which is everywhere from the brain to bone to muscle to the clitoris to the tear ducts, and why reducing testosterone in women to a libido drug misses the full picture entirely. Guest links: Kelly Casperson, MD Kelly Casperson (Instagram) Kelly Casperson (YouTube) You Are Not Broken (Apple Podcasts) Books: “You Are Not Broken,” by Kelly Casperson, MD "The Menopause Moment," by Kelly Casperson, MD  “The New Perimenopause,” by Dr. Mary Claire Haver “The New Menopause,” by Dr. Mary Claire Haver "Sexual Behavior in the Human Female," by Alfred Kinsey To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices
  • Sexual Health, Libido, and Orgasm: What Medicine Missed with Dr. Kelly Casperson 21.04.2026 1時間 7分
    In this episode of unPAUSED, Dr. Mary Claire Haver sits down with Dr. Kelly Casperson, a urologist, author, and host of the podcast “You Are Not Broken”. Dr. Casperson trained in a specialty that treats both men and women, which gave her an early and clear view of the gender gap in sexual healthcare. That disparity became the driving force behind her work, her two books You Are Not Broken and The Menopause Moment, and her clinic, the Casperson Clinic. Together they cover the full landscape of what women were never taught, what medicine has missed, and what actually works for female sexual health, libido, desire, and sexual dysfunction in midlife. The conversation gets straight to what most women were never told: that the orgasm gap between heterosexual men and women has not improved in decades, and that the silence around female sexual health has never been about a lack of science. It has been about a lack of priority. Guest links: Kelly Casperson, MD Kelly Casperson (Instagram) Kelly Casperson (YouTube) You Are Not Broken (Apple Podcasts) Books: “Sexual Behavior in the Human Female,” by Alfred Kinsey “You Are Not Broken,” by Kelly Casperson, MD To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices
  • Plant Medicine for Menopause: What Science and Ancient Healing Say Actually Works 14.04.2026 1時間 10分
    In this episode of unPAUSED, Dr. Mary Claire Haver sits down with Dr. Suzanne Gilberg-Lenz, a board-certified OB-GYN, integrative medicine expert, and author with nearly 30 years of clinical experience, including training in Ayurvedic medicine spanning almost two decades. Dr. Gilberg-Lenz is the Chief Clinical Officer of Monarch, a membership-based healthcare practice built to restore what modern medicine has nearly eliminated: time, relationship, and trust between women and their clinicians. Dr. Haver and Dr. Gilberg-Lenz open with a question that sits at the heart of women's midlife health: why does the current healthcare system consistently fail to see women clearly? Dr. Gilberg-Lenz explains why the system is not built for humans but for shareholders, reimbursement structures, and productivity metrics that reward procedures over listening. She breaks down the difference between burnout and moral injury, why physicians are leaving traditional medicine in record numbers, and what it actually costs women when their doctors are structurally prevented from knowing them. The conversation traces how the 1910 Flexner Report reshaped American medicine, shutting down Black medical colleges, eliminating part-time schools where women trained, and marginalizing plant-based and indigenous healing traditions in ways that still define clinical practice today. Guest links: Dr. Suzanne Dr. Suzanne Gilberg-Lenz (Instagram) Dr. Suzanne Gilberg-Lenz (YouTube) Dr. Suzanne Gilberg-Lenz (LinkedIn) Dr. Suzanne Gilberg-Lenz (Facebook)Dr. Suzanne Gilberg-Lenz (X) Books: “Menopause Bootcamp: Optimize Your Health, Empower Your Self, and Flourish as You Age,” by Dr. Suzanne Gilberg-Lenz “The Myth of Aging: A Prescription for Emotional and Physical Well-Being,” by Dr. Arnold Gilberg “The New Perimenopause,” by Dr. Mary Claire Haver “The New Menopause,” by Dr. Mary Claire Haver For full show notes, please click here. To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices
  • The Missing Piece in Longevity: The Top Gerontologist on Aging, Joy, and the Science of Thriving 07.04.2026 1時間 21分
    In this episode of unPaused, Dr. Mary Claire Haver sits down with Dr. Kerry Burnight, a gerontologist and national leader in aging research who spent 18 years teaching geriatric medicine at the University of California Irvine School of Medicine and is the author of Joyspan: The Art and Science of Thriving in Life's Second Half. Dr. Burnight brings a framework that is especially relevant for women navigating menopause and midlife: the key to good longevity is not how long you live. It is how much you love the life you are living. Dr. Haver and Dr. Burnight begin with the concept of joyspan itself, a term Dr. Burnight coined to name the missing piece between lifespan and healthspan. Drawing on the American Psychological Association's definition of joy as wellbeing and life satisfaction, they explore why joy is not a luxury add-on to healthy aging but a measurable, cultivatable vital sign. Dr. Burnight explains the distinction between joy and happiness, why happiness is circumstantial while joy is an inside job, and how Viktor Frankl's research on finding meaning under extreme suffering forms the scientific and philosophical foundation of her framework. They also discuss Yale University research showing that aging beliefs alone can impact longevity by up to seven and a half years, influence inflammation levels, and affect disease expression, making the way women think about getting older one of the most powerful health interventions available. Guest links: Dr. Kerry Burnight Dr. Kerry Burnight (Instagram) Dr. Kerry Burnight (LinkedIn) Books:“Joyspan: The Art and Science of Thriving in Life's Second Half,” by Dr. Kerry Burnight “The New Perimenopause,”⁠ by Dr. Mary Claire Haver ⁠"The New Menopause"⁠ by Dr. Mary Claire Haver For full show notes, please click here. To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices
  • The Perimenopause Masterclass: Anxiety, Brain Fog, Broken Sleep, Weight Gain & GLP-1s 31.03.2026 1時間 6分
    In this episode of “unPAUSED,” Dr. Mary Claire Haver answers the questions she gets asked most, sitting down solo to address what perimenopause actually is, why it starts in the brain before it ever shows up in bloodwork, and why so many women experiencing anxiety, brain fog, broken sleep, and unexplained weight gain are dismissed, misdiagnosed, or handed prescriptions for symptoms that have a hormonal root. Perimenopause is not a waiting room. It is its own distinct biological phase, a seven to ten year hormonal transition that begins long before periods stop and touches every organ system in the body. And yet most women are never taught to recognize it. Dr. Haver breaks down the hormonal chaos of perimenopause, revealing why estrogen does not simply decline but surges and crashes erratically as the brain floods the ovaries with luteinizing hormone (LH) and follicle stimulating hormone (FSH) in a desperate attempt to produce more, and why a single blood draw will almost never tell the full story. She answers the metabolic questions she hears constantly, explaining how visceral fat can double or triple during the transition with no changes in diet or exercise, why LDL cholesterol rises an average of 20%, and how cardiovascular risk, insulin resistance, bone density loss, and inflammation are all woven into the same story medicine has largely failed to tell women. Guest links: The 'Pause Wellness The ‘Pause Life Dr. Mary Claire Haver (Instagram) Dr. Mary Claire Haver (YouTube) Books: “The New Perimenopause,” by Dr. Mary Claire Haver "The New Menopause" by Dr. Mary Claire Haver “Weightless: A Doctor's Guide to GLP-1 Medications, Sustainable Weight Loss, and the Health You Deserve,” by Rocio Salas-Whalen To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices
  • Brain Fog, Memory Loss, and Alzheimer’s Risk During Menopause with Dr. Lisa Mosconi 24.03.2026 1時間
    In this episode of unPAUSED, Dr. Mary Claire Haver continues her conversation with Dr. Lisa Mosconi, neuroscientist and associate professor of neuroscience in neurology and radiology at Weill Cornell Medicine, New York Presbyterian Hospital. Dr. Mosconi directs the Alzheimer's Prevention Program, including the NIH-funded Women's Brain Initiative and the Alzheimer's Prevention Clinic, and was recently named director of the $50 million Program in Women's Health, Cutting Alzheimer's Risk Through Endocrinology. She is also the author of the bestselling book The Menopause Brain. Dr. Mosconi and Dr. Haver go deeper into why brain fog, memory lapses, and cognitive changes in midlife are not just frustrating. They are biologically significant, and for some women, they may signal an inflection point for Alzheimer's risk. The conversation covers the statistics women are rarely given starting at age 45, a woman has twice the risk of Alzheimer's as a man of the same age. Women are also twice as likely to be diagnosed with anxiety or depression, three times more likely to develop an autoimmune disorder affecting the brain, four times more likely to suffer from migraines, and more likely to be killed by a stroke after menopause. Guest links: Lisa Mosconi Lisa Mosconi (Instagram) Lisa Mosconi (Facebook)Lisa Mosconi Bio (LEAP)Books: “The Menopause Brain: New Science Empowers Women to Navigate the Pivotal Transition with Knowledge and Confidence,” by Lisa Mosconi “The XX Brain: The Groundbreaking Science Empowering Women to Maximize Cognitive Health and Prevent Alzheimer's Disease,” by Lisa Mosconi “Brain Food: The Surprising Science of Eating for Cognitive Power,” by Lisa Mosconi “The New Perimenopause,”⁠ by Dr. Mary Claire Haver ⁠"The New Menopause"⁠ by Dr. Mary Claire Haver For full show notes, please click here. To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices
  • The Alzheimer's Prevention Plan for Women: Hormones, Sleep, and Nutrition with Dr. Lisa Mosconi 17.03.2026 1時間 6分
    In this episode of unPAUSED, Dr. Mary Claire Haver sits down with Dr. Lisa Mosconi, a neuroscientist and associate professor of neuroscience in neurology and radiology at Weill Cornell Medicine, New York Presbyterian Hospital. Dr. Mosconi directs the Alzheimer's Prevention Program, including the NIH-funded Women's Brain Initiative and the Alzheimer's Prevention Clinic, and was recently named director of the $50 million Program in Women's Health, Cutting Alzheimer's Risk Through Endocrinology. She is also the author of the bestselling book The Menopause Brain. This conversation is about prevention. Dr. Mosconi has spent decades building the science that shows Alzheimer's risk in women is neither inevitable nor untreatable and that the choices women make in midlife around hormones, sleep, and nutrition have a direct, and measurable, impact on the brain's long-term health.  Together, they explore why two thirds of all Alzheimer's patients are women and what role menopause plays in that disparity. Dr. Mosconi explains the difference between the rare genetic mutations that directly cause Alzheimer's, found in roughly 2% of patients, and the risk factors that shape outcomes for the other 98%, including the distinction between early and late onset disease and between sporadic and familial Alzheimer's. Both share their own family histories with dementia and what that means for their personal risk. Guest links: Lisa Mosconi Lisa Mosconi (Instagram) Lisa Mosconi (Facebook) Lisa Mosconi Bio (LEAP) Books: “The Menopause Brain: New Science Empowers Women to Navigate the Pivotal Transition with Knowledge and Confidence,” by Lisa Mosconi “The XX Brain: The Groundbreaking Science Empowering Women to Maximize Cognitive Health and Prevent Alzheimer's Disease,” by Lisa Mosconi“Brain Food: The Surprising Science of Eating for Cognitive Power,” by Lisa Mosconi “The New Perimenopause,”⁠ by Dr. Mary Claire Haver ⁠"The New Menopause"⁠ by Dr. Mary Claire Haver For full show notes, please click here. To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices
  • The Sleep Crisis in Menopause: Insomnia, Sleep Apnea & Solutions 10.03.2026 1時間 19分
    Poor sleep during perimenopause and menopause isn't just exhausting—it's linked to increased cardiovascular disease risk, depression, anxiety, weight gain, cognitive decline, and reduced quality of life. Yet for decades, women's sleep complaints have been minimized, dismissed, or blamed on just getting older. In this episode, Dr. Mary Claire Haver sits down with board-certified sleep medicine specialist Dr. Andrea Matsumura to unpack what's really happening to women's sleep during the menopause transition and what we can actually do about it. Dr. Matsumura completed her medical degree at the University of Texas Health Science Center San Antonio and her internal medicine residency in Portland, Oregon before returning to Oregon Health & Science University for a fellowship in sleep medicine, where she discovered the critical connection between women's hormones and sleep disorders. Guest links: Dr. Andrea Matsumura (Instagram) Dr. Andrea Matsumura (Facebook) Dr. Andrea Matsumura (LinkedIn) Dr. Andrea Matsumura  The D.R.E.A.M. Sleep Method: A Midlife Woman’s Guide to Restoring Rest Articles Worldwide estimation of restless legs syndrome: a systematic review and meta-analysis of prevalence in the general adult population (Journal of Sleep Research) Association Between Obstructive Sleep Apnea and Cardiovascular Risk: A Systematic Review and Meta-Analysis of Prospective Cohort Studies (Medicina) Why sleep apnea deserves priority in public health: a call to action (European Journal of Public Health) Poor Quality Control of Over-the-Counter Melatonin: What They Say Is Often Not What You Get (Journal of Clinical Sleep Medicine) Quantity of Melatonin and CBD in Melatonin Gummies Sold in the US (JAMA) Sleep disorders impact hormonal regulation: unravelling the relationship among sleep disorders, hormones and metabolic diseases (Diabetology & Metabolic Syndrome) Comorbid Insomnia and Obstructive Sleep Apnea (COMISA): Current Concepts of Patient Management (International Journal of Environmental Research and Public Health) Chronobiological perspectives: Association between meal timing and sleep quality (PLOS One) Effects of red light on sleep inertia (Nature and Science of Sleep) Other Resources Seven or more hours of sleep per night: A health necessity for adults (American Academy of Sleep Medicine) The D.R.E.A.M Sleep Essentials Sleep Goddess Archetype Quiz American Academy of Sleep Medicine “The New Perimenopause,”⁠ by Dr. Mary Claire Haver ⁠"The New Menopause"⁠ by Dr. Mary Claire Haver For full show notes, please click here. To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices
  • Katie Couric on Truth, Trust, and Women's Health 03.03.2026 1時間 16分
    From her groundbreaking televised colonoscopy to her breast cancer journey, Katie Couric has turned personal experience into powerful advocacy for the health issues medicine has overlooked. This week on unPaused, Dr. Mary Claire Haver sits down with Katie Couric, award-winning journalist, founder of Katie Couric Media, co-founder of Stand Up To Cancer, and author of the New York Times bestseller Going There. Katie spent 15 years co-hosting the Today Show, served as the first solo female anchor of CBS Evening News, and has interviewed nearly every president, world leader and cultural voice of the last four decades. Together, they explore Katie's journey from growing up in Arlington, Virginia, where her parents instilled the importance of education and financial independence, to breaking barriers in network news while navigating profound personal loss. Katie opens up about losing her husband Jay to stage four colon cancer when her daughters were six and two, how that tragedy launched her into cancer advocacy, and why she made the decision to have a colonoscopy on live television — a moment that changed screening rates across America and took the stigma out of a life-saving procedure. Guest links: Katie Couric Media Katie Couric (Instagram) Katie Couric (TikTok) Katie Couric (Facebook) Katie Couric Media (Instagram) Katie Couric (YouTube) Katie Couric (X) Katie Couric (LinkedIn) Katie Couric (Substack) Next Question with Katie Couric (Apple Podcasts) Books:"The Feminine Mistake: Are We Giving Up Too Much?," by Leslie Bennetts “The New Perimenopause,”⁠ by Dr. Mary Claire Haver ⁠"The New Menopause"⁠ by Dr. Mary Claire Haver To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices
  • The Sex Life Nobody Warned You About: What a Top Sexual Medicine Expert Wants You To Know 24.02.2026 57分
    Most women go through decades of marriage, menopause and midlife without ever having an honest conversation with a doctor about their sex life. Not because they don't want one — but because most physicians were never trained to have it. This week on unPaused, Dr. Mary Claire Haver sits down with Dr. James Simon, a professor of obstetrics and gynecology at George Washington University, board-certified OB-GYN, reproductive endocrinologist, and certified sexual counselor with more than 800 published papers in menopause and sexual medicine. Dr. Simon is a past president of the International Society for the Study of Women's Sexual Health (ISSWSH) and one of the most published clinicians in modern menopause care. Dr. Simon has spent his career treating what most doctors never address — the full picture of how sex, desire, pain and intimacy change for both women and men as they age. He treats couples together, and what he has witnessed across thousands of relationships is that the problems are rarely one person's fault, rarely unsolvable, and almost always rooted in something nobody warned them about. Guest links: James Simon (IntimMedicine Specialists) James Simon (Instagram) James Simon (YouTube) Articles: What if the Women’s Health Initiative had used transdermal estradiol and oral progesterone instead? (Menopause) Erectile Dysfunction (StatPearls) Should we be prescribing testosterone to perimenopausal and menopausal women? A guide to prescribing testosterone for women in primary care (British Journal of General Practice) The Benefits and Harms of Systemic Testosterone Therapy in Postmenopausal Women With Normal Adrenal Function: A Systematic Review and Meta-analysis (The Journal of Clinical Endocrinology & Metabolism) Other Resources: Women’s Health Initiative The North American Menopause Society Releases Its 2022 Hormone Therapy Position Statement (NAMS) International Society for the Study of Women's Sexual Health (ISWSH)  FDA panel rejects testosterone patch for women on safety grounds (The BMJ) The Saga of Testosterone for Menopausal Women at the Food and Drug Administration (FDA) (The Journal of Sexual Medicine) Sexual Medicine Society of North America (SMSNA) Books:“Restore Yourself: A Woman's Guide to Reviving her Sexual Desire and Passion for Life,” by James Simon and Victoria Houston “The New Perimenopause,”⁠ by Dr. Mary Claire Haver ⁠"The New Menopause"⁠ by Dr. Mary Claire Haver For full show notes, please click here. To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices
  • Building a Menopause Brand: Naomi Watts on HRT, Hot Flashes & Hollywood 17.02.2026 1時間
    This week on unPaused, Dr. Mary Claire Haver sits down with Naomi Watts, Academy Award nominated actress, entrepreneur, and New York Times bestselling author of Dare I Say It. Naomi's career spans decades in Hollywood, from her breakthrough role in David Lynch's Mulholland Drive to recent work with directors like Ryan Murphy and Lena Dunham. After receiving a shocking early menopause diagnosis at 36 while struggling with fertility, Naomi spent years navigating untreated symptoms in silence before becoming an unexpected advocate for millions of women facing midlife transitions. In 2021, she founded Stripes Beauty, a menopause focused skincare and wellness brand built on community, education, and celebrating womens earned wisdom rather than promising to reverse time. In this conversation, Dr. Haver and Naomi explore the reality of growing up across continents after losing her father at eight years old, the decade long struggle to break into Hollywood, and the moment at 30 when her acting career finally launched. Naomi opens up about the devastating news from her doctor that she was approaching menopause at 36, the desperate fertility journey that followed including traveling to China for herbal remedies and extreme dietary changes, and the perimenopause symptoms she dismissed as allergies or stress in her late twenties including night sweats, migraines, brain fog, and sleep disruption. Guest links: Naomi Watts (Instagram) Naomi Watts (IMDB) Stripes Beauty Other Resources Davina McCall (Instagram) Stacy London (Instagram) Dr. Jen Gunter Books “Inconceivable, 20th Anniversary Edition: A Woman's Triumph over Despair and Statistics,” by Julia Indichova “Dare I Say It: Everything I Wish I'd Known About Menopause,” by Naomi Watts“The New Perimenopause,” by Dr. Mary Claire Haver ⁠"The New Menopause"⁠ by Dr. Mary Claire Haver To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices
  • Female Libido in Menopause: Desire Loss, Biology & Solutions with Cindy Eckert 10.02.2026 1時間 7分
    This week on unPaused, Dr. Mary Claire Haver sits down with Cindy Eckert, founder and CEO of Sprout Pharmaceuticals and creator of Addyi, the first FDA approved treatment for low libido in women. Cindy is a pharmaceutical entrepreneur who began her career at Merck before founding her first company in 2007, focusing on undermarketed FDA approved products. After successfully building and selling a male sexual health company, she became the only woman running a sexual health company and witnessed firsthand the stark contrast between how medicine treats male versus female sexual dysfunction. Her journey to bring Addyi to market became a cultural battle about whether women's sexual desire matters, leading to two FDA rejections, public hearings, and ultimately a historic approval in 2015 after a six year fight. In this conversation, Dr. Haver and Cindy explore how Addyi works differently from Viagra, targeting brain chemistry and desire rather than blood flow and arousal. Cindy explains that Addyi is a mood drug originally developed for depression that showed an unexpected effect on female libido during clinical trials. The medication works on neurotransmitters in the brain, building over approximately eight weeks to restore spontaneous thoughts, fantasies, and desire in women with hypoactive sexual desire disorder or HSDD. She walks through the massive clinical trial requirements, including 13,000 patients compared to Viagra's 4,000, and the three things they had to prove with statistical significance versus placebo: increased interest in sex, more satisfying sexual experiences, and decreased distress from the condition. ADDYI, flibanserin, is for women

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