MDS Podcast

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• A cross-sectional study of PPMI participants using alpha-synuclein seed amplification as a biomarker 12.06.2023

  In this episode Dr. Tiago Outeiro talks with Dr. Andrew Siderowf about the exciting new results in his most recent publication on alpha-synuclein seed amplification assay. Read the article.
• A lifetime of experiences and learnings - MDS 40th Anniversary 08.12.2025

  To celebrate the 40th Anniversary of the MDS, Dr. Michele Matarazzo sits down with two key leaders of the MDS Pan-American section, Dr. Cynthia Comella and Dr. Oscar Gershanik. Together they discuss how they got involved in the society, what they are most proud of, and what the Society means to them, both professionally and personally.
• A new pathway to find structural variations in inherited neurological cases - the SCA4 example 29.04.2024

  Dr. Sarah Camargos interviews Dr. Zhonghbo Chen and Prof. Henry Houlden, first and senior author of a MDJ paper exploring a GGC repeat expansion in the ZFHX3 gene associated with spinocerebellar ataxia type 4. They describe a criative methodology to find a gene in a family with a Swedish ancestry. Journal CME is available until April 04, 2025 Read the article.
• A post-hoc analysis of the Prasinezumab trial in early Parkinson's disease 15.07.2024

  Dr. Gennaro Pagano discusses the findings of the post-hoc analysis of the PASADENA trial, a study using the monoclonal antibody Prasinezumab directed at aggregated α-synuclein, where motor progression trajectories differed between active and placebo groups. Read article »
• Acetylcholine nuclei atrophy predicts gait changes in Parkinson's disease 01.03.2021

  Dr. Michele Matarazzo interviews Dr. Nicola Ray on a recently published article that demonstrates a relationship between changes in cholinergic nuclei in MRI and future gait disorders in Parkinson's disease. Read the article
• Achievements and future goals: An interview with MDS President • 2025 MDS Congress 20.10.2025

  Dr. Victor Fung reflects on his term as MDS President and his appreciation for the accomplishments that were achieved. He further discusses his future hopes and goals of the Society and the #mdscongress.
• Advanced therapies for Parkinson's disease: Are they all the same? 22.03.2019

  Dr. K. Ray Chaudhuri discusses with Dr. Michele Matarazzo his article on the differences between subthalamic nucleus DBS, intrajejunal levodopa and apomorphine infusion in Parkinson's, published in the March 2019 issue of the Movement Disorders journal. Read the article
• Advancements in Dystonia Treatments | Congress 2023 18.09.2023

  What innovations in dystonia treatments do we have to look forward to? Dr. Mark Edwards sits down with Dr. Sarah Camargos to answer that vary question.
• Advances in Supranuclear Palsy Research | Congress 2022 01.10.2022

  Despite the challenge of studying rare conditions like PSP, Dr. Yaroslau Compta discusses with Dr. Eduardo de Pablo-Fernández how leaps forward in recent advances could make us rethink the way we approach the condition.
• An interview with Claudia Trenkwalder | Congress 2021 30.09.2021

  Dr. Sara Schaefer discusses with Dr. Claudia Trenkwalder the 2021 Virtual MDS Congress, her tenure as the MDS president, and her hopes for the future of the MDS.
• An Interview with MDS President Francisco Cardoso | Congress 2022 01.10.2022

  MDS President Francisco Cardoso shares with Dr. Michele Matarazzo the important takeaways from this year's Congress that will shape the future of movement disorders and the Society.
• An online mindfulness-based group intervention for tics 21.10.2024

  Dr. Hannah E. Reese and Mr. W. Alan Brown discuss their pilot study of a mindfulness-based group virtual intervention for tic disorders, that was co-developed with patients. Journal CME is available until August 21, 2025 Read the article.
• Antibiotics and Parkinson's disease 31.03.2020

  In this issue Dr. Filip Sheperjans shares the results of the article published in the March 2020 issue of the Movement Disorders journal on the effect of antibiotic exposure on the risk of developing Parkinson's disease. Read the article
• Anti-inflammatory drugs use impacts the risk of developing PD in LRRK2 mutation carriers 09.11.2020

  Dr. Marta San Luciano shares the main findings of the recently published article on the impact of non-steroidal anti-inflammatory drugs use on the risk of developing PD in a large LRRK2 mutation carriers cohort. Read the article
• Anxiety in parkinson's disease and its correlates in mri-based functional connectivity 01.02.2021

  Dr. Michele Matarazzo interviews Dr. Rosa De Micco on the functional MRI correlates of anxiety in Parkinson's disease, highlighting the main results of the article she recently published on the topic in the Movement Disorders journal.Read the article
• Approach to neuroimaging in Parkinsonisms 17.01.2022

  Dr. Sara Schaefer discusses with Professor Antonio Strafella and Dr. Cecilia Peralta their work from the MDS Neuroimaging Study Group published in Movement Disorders Clinical Practice on a "Pragmatic Approach on Neuroimaging Techniques for the Differential Diagnosis of Parkinsonisms." Read the article
• Approach to reviewing a review article 16.05.2022

  For the sixth episode of the special series focused on the peer review process, Dr. Shweta Prasad speaks with Prof. Christine Klein to discuss the approach to reviewing a review article.
• Are hyposmia and REM sleep behavior disorder reliable indicators of Lewy body pathology? 10.03.2025

  There is an important role for cost-effective clinical biomarkers in the diagnosis of Parkinson's disease. Dr. Eduardo de Pablo-Fernández and Dr. Cecilia Tremblay discuss how accurate hyposmia and REM sleep behavior disorder can predict Lewy pathology in a non-selected population using data from the Arizona clinicopathological study on Aging and Neurodegeneration. Read the article.
• Artificial intelligence in the diagnostic approach of chronic ataxias 07.07.2025

  Dr. Hugo Morales interviews Drs. Malco Rossi and Lucas Alessandro about their work on an AI-powered virtual assistant designed to aid in the diagnosis of chronic ataxias. They discuss how the assistant performed when put to the test, evaluating its diagnostic accuracy head-to-head against movement disorder experts. Journal CME is available until May 21, 2026 Read the article.
• Ataxia Series: Beyond the cerebellum - Non-motor features and multisystem care in genetic ataxias 11.05.2026

  Genetic ataxias have many non-motor features, such as fatigue, sleep disorders, and cognitive dysfunction. In this episode, Dr. Orlando Barsottini and Dr. Christofer Stephen discuss the most common non-motor symptoms and how to approach them.