Dr Karan Explores

Epizodai

• The Prostate Cancer Warning Signs Men Should Know 01.06.2026 41min

  Prostate cancer is the most common cancer in men, but it often has no obvious symptoms.In this episode, Dr Karan Rajan speaks with Professor Prabhakar Rajan, a urologist and prostate cancer specialist, about prostate cancer risk, PSA testing, MRI scans, treatment choices, testicular cancer, and why men often delay asking for help.They discuss when urinary symptoms, blood in urine, persistent back pain, testicular lumps, and changes in sexual or urinary function should be checked. While also unpacking the controversy around PSA screening, overdiagnosis, active surveillance, robotic prostatectomy, focal therapy, radiotherapy, and the future of AI in prostate cancer diagnosis.This is a practical, evidence-led conversation about men’s health, prostate cancer, testicular cancer, screening, stigma, and the questions men should feel able to ask their doctor.💩 Head to https://loamscience.com/products/loam-prebiotic-fiber-formula?utm_source=youtube&utm_medium=social&utm_campaign=drkaranexplores to try LOAM - and get an additional 10% with code POD10.💊 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe🚽 Discover Throne's incredible new smart toilet device at http://thronescience.com📘 For more useful science for your everyday life, grab my best selling book "This Book May Save Your Life": https://geni.us/DrKaranBook📕 Get my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation🤖 Discover my digital twin here: http://DrKaran.ai🧬 Sign up for my Microbiome Course waitlist: https://drkaran.kit.com/microbiome-course-waitlistAbout Dr Karan:Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health.📱Connect with me:Instagram: / drkaranrajanFacebook: / drkaranrTikTok: / dr.karanrX: / drkaranrajanWebsite: www.drkaranrajan.com00:00 Prostate cancer symptoms men should know01:02 Meet Professor Prabhakar Rajan02:00 Why prostate cancer can have no symptoms05:28 Are we overtreating early prostate cancer?06:31 Surgery, radiotherapy and active surveillance07:51 How MRI changed prostate cancer diagnosis08:30 Why men avoid prostate health conversations10:24 Prostate cancer risk in Black men13:00 PSA tests: useful, imperfect and controversial21:56 Why treatment decisions must be personal24:39 Questions to ask before prostate surgery25:10 Active surveillance and focal therapy26:20 Nerve-sparing prostatectomy explained28:22 Sexual function after prostate surgery30:06 Testicular cancer symptoms in young men31:18 What to do if you find a testicular lump34:17 How to check your testicles properly38:05 Could AI help diagnose prostate cancer?40:25 The one thing men should do for their health41:02 Why men’s health needs better conversations#MensHealth #DrKaranRajan #MensHealthPodcast #Podcast
• Gut Health Expert: Diet Is Only 20% Of The Puzzle 25.05.2026 44min

  Gut health is about much more than what you eat. In this episode, Dr Karan Rajan speaks with Kaitlin Colucci about the gut-brain connection, IBS, bloating, stress, sleep, meal timing, yoga, and the nervous system.They discuss why diet may only be one part of the gut health puzzle, how stress can affect digestion, why eating on the go may worsen symptoms, and how simple habits like breathwork, better sleep, mindful eating, fibre, and movement can support a healthier gut.Kaitlin explains how the gut and brain communicate through the nervous system, why IBS is often misunderstood, and why gut symptoms are not always “just a food problem”.This conversation also explores ultra-processed foods, caffeine, alcohol, artificial sweeteners, protein bars, fizzy drinks, meal timing, the migrating motor complex, yoga for IBS, and the role of social connection in digestion.In this episode: -Why gut health is not just about diet- How stress affects digestion and gut motility- What the gut-brain axis actually means- Why IBS can involve nervous system sensitivity- How sleep and circadian rhythm affect the gut- Why grazing all day may worsen bloating- How yoga, meditation, and breathwork may support IBS symptoms- Practical ways to eat more mindfully- The role of fibre, meal timing, and food diversity💩 Head to https://loamscience.com/products/loam-prebiotic-fiber-formula?utm_source=youtube&utm_medium=social&utm_campaign=drkaranexplores to try LOAM - and get an additional 10% with code POD10.💊 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe🚽 Discover Throne's incredible new smart toilet device at http://thronescience.com📘 For more useful science for your everyday life, grab my best selling book "This Book May Save Your Life": https://geni.us/DrKaranBook📕 Get my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation🤖 Discover my digital twin here: http://DrKaran.ai🧬 Sign up for my Microbiome Course waitlist: https://drkaran.kit.com/microbiome-course-waitlistAbout Dr Karan:Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health.Connect with me:Instagram: / drkaranrajanFacebook: / drkaranrTikTok: / dr.karanrX: / drkaranrajanWebsite: www.drkaranrajan.com 00:00 Welcome Kaitlin Colucci 01:34 Gut Health Rapid-Fire 07:42 Why Eating on the Go Affects Digestion 08:23 What People Miss About Gut Health 09:04 The Gut-Brain Connection Explained 11:16 How Stress Impacts Digestion 12:21 IBS, Gut Sensitivity & Visceral Hypersensitivity 15:26 How to Regulate Your Nervous System 16:29 Mindful Eating, Food Diaries & Eating Without Distractions 19:04 Reconnecting With Food & Social Eating 22:13 Sleep, Circadian Rhythm & Gut Health 23:37 Meal Timing, Grazing & the Gut “Clean-Up Crew” 28:25 Yoga, IBS & Final Gut Health Advice 36:46 Modern Gut Health & Final Takeaways#GutHealth #IBS #GutBrainAxis #DrKaranRajan #KaitlinColucci
• The Male Fertility Crisis No One Is Talking About 18.05.2026 54min

  Male fertility is declining, but sperm count is only part of the story.Dr Karan Rajan chats with Professor Sheryl Homa about male infertility, sperm DNA damage, lifestyle, heat exposure, environmental toxins, microbiome health, and why men’s fertility is often overlooked.Professor Homa explains why infertility should be treated as a health issue for both partners, what semen analysis can and cannot tell you, and why sperm health may reflect wider problems such as diabetes, inflammation, kidney disease, hemochromatosis, stress and metabolic health.In this conversation, we cover:• Why global sperm counts appear to be falling00:00 Sperm Counts Are Falling GloballyHead to https://loamscience.com/products/loam-prebiotic-fiber-formula?utm_source=youtube&utm_medium=social&utm_campaign=drkaranexplores to try LOAM - and get an additional 10% with code POD10.Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribeDiscover Throne's incredible new smart toilet device at http://thronescience.comFor more useful science for your everyday life, grab my best selling book "This Book May Save Your Life": https://geni.us/DrKaranBookGet my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformationDiscover my digital twin here: http://DrKaran.aiSign up for my Microbiome Course waitlist: https://drkaran.kit.com/microbiome-course-waitlist About Dr Karan:Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health.Connect with me:Instagram: / drkaranrajanFacebook: / drkaranrTikTok: / dr.karanrX: / drkaranrajanWebsite: www.drkaranrajan.com#MaleFertility #SpermHealth #MensHealth #DrKaran #podcast
• The Gut Health Myths You Still Believe (And What Actually Works) 11.05.2026 56min

  Your gut microbiome affects far more than digestion. In this episode, Dr Karan Rajan sits down with gut health expert Jordan Haworth to break down the science of gut health, probiotics, fibre, acid reflux, oral microbiome health, fermented foods, GLP-1, bloating, sleep, fasting, and the everyday habits that actually improve your microbiome.Here is a link to preorder Jordan's new book out June 18th: How to Gut Health: Science-backed hacks for immunity, metabolism and better sleephttps://lnk.to/howtoguthealthWe speak about:The connection between oral health and gut healthWhy chewing food properly changes digestionThe truth about probiotics and fermented foodsBest foods for beneficial gut bacteriaGut-friendly habits that improve digestion naturallyAcid reflux hacks backed by scienceWhether greens powders and fibre gummies are worth itThe role of fasting, sleep, exercise and stress on the microbiomeWhy gut health affects metabolism, immunity, mood and more 00:00 Gut Health Starts In The Mouth 01:15 Why Chewing Improves Digestion 04:10 Eating Slowly, GLP-1 & Feeling Full 06:55 Oral Microbiome, Mouthwash & Gum Disease 11:25 Acid Reflux & The Lower Oesophageal Sphincter 19:40 Bitter Foods, Coffee & Digestion 22:05 Nausea, Ginger & Fart Walking 31:00 Foods That Feed Bifidobacteria 34:00 Fermented Foods & Lactic Acid Bacteria 37:50 Slow-Fermenting Fibres For The Colon 40:35 Prebiotics, Probiotics & Postbiotics Explained 50:40 Nature, Sleep, Exercise & The Microbiome 53:10 Fasting, Akkermansia & Gut Rest 54:45 Sweeteners, Vinegar, Greens Powders & Fibre GummiesHead to https://loamscience.com/products/loam-prebiotic-fiber-formula?utm_source=youtube&utm_medium=social&utm_campaign=drkaranexplores to try LOAM - and get an additional 10% with code POD10.Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribeDiscover Throne's incredible new smart toilet device at http://thronescience.comFor more useful science for your everyday life, grab my best selling book "This Book May Save Your Life": https://geni.us/DrKaranBookGet my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformationDiscover my digital twin here: http://DrKaran.aiSign up for my Microbiome Course waitlist: https://drkaran.kit.com/microbiome-course-waitlistAbout Dr Karan:Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor.Connect with me:Instagram: / drkaranrajanFacebook: / drkaranTikTok: / dr.karanrX: / drkaranrajanWebsite: www.drkaranrajan.com#GutHealth #Microbiome #DigestiveHealth #Probiotics #DrKaran
• Why Nothing Feels Fun Anymore: Dopamine, Phones & Brain Rot 04.05.2026 53min

  Your phone is not just distracting you, it may be changing what your brain finds rewarding.In this episode of Dr Karan Explores, Dr Karan Rajan speaks with neuroscientist TJ Power, founder of DOSE Lab, about dopamine, phone addiction, AI, “brain rot,” digital anhedonia, and why modern technology can make ordinary life feel less pleasurable. TJ’s DOSE framework focuses on dopamine, oxytocin, serotonin, and endorphins, the four brain chemicals he says are being disrupted by the way modern humans live. This conversation explores why so many of us feel stuck in loops of scrolling, distraction, apathy, and low motivation, and what it takes to reset our relationship with stimulation without pretending technology is “bad.” TJ shares why he believes 72 hours without screens can feel transformative, why boredom is harder than it sounds, and why becoming a “professional unplugger” may be one of the most important skills for the next generation. In this episode, we cover:What dopamine actually does beyond the online “dopamine detox” clichésWhy phones, short-form content, sugar, alcohol, and AI can hijack reward pathways“Digital anhedonia”: Why normal life can start to feel dull or boringThe 72-hour unplugged experiment and what happens by day two and day threeWhy boredom, stillness, walking, and doing nothing can restore creativityThe default mode network and why your best ideas may need silenceAI, “brain rot,” passive screen time, and outsourcing your thinkingHow to become a “professional unplugger” without quitting modern life🎬 Chapters01:13 – Why Modern Life Is Rewiring Our Brains03:18 – What Dopamine Actually Does06:06 – Phones, Short-Form Content & Dopamine Overload09:28 – Why Nothing Feels Fun Anymore12:27 – How to Break the Stimulation Loop14:01 – 72 Hours Without Screens: What Happens to Your Brain17:49 – Boredom, Creativity & the Default Mode Network21:41 – Instant Gratification and the Collapse of Waiting22:47 – AI, Brain Rot & Outsourcing Your Thinking29:34 – Passive Screen Time vs Active Technology Use32:37 – Are Some Brains More Dopamine-Hungry?39:04 – Stillness, Silence & Rebuilding Attention42:35 – AI Relationships, Oxytocin & Artificial Connection46:10 – Why Technology Evolves Faster Than the Human Brain48:27 – Dopamine and Why Time Feels Faster52:03 – Becoming a Professional Unplugger53:31 – Final Takeaway: Quiet Mornings, Coffee & No Phone💩 Head to https://loamscience.com/products/loam-prebiotic-fiber-formula?utm_source=youtube&utm_medium=social&utm_campaign=drkaranexplores to try LOAM - and get an additional 10% with code POD10.💊 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe🚽 Discover Throne's incredible new smart toilet device at http://thronescience.com📘 For more useful science for your everyday life, grab my best selling book "This Book May Save Your Life": https://geni.us/DrKaranBook📕 Get my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation🤖 Discover my digital twin here: http://DrKaran.ai🧬 Sign up for my Microbiome Course waitlist: https://drkaran.kit.com/microbiome-course-waitlistAbout Dr Karan:Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health.📱Connect with me:Instagram: / drkaranrajanFacebook: / drkaranrTikTok: / dr.karanrX: / drkaranrajanWebsite: www.drkaranrajan.com#Dopamine #BrainRot #PhoneAddiction #Neuroscience #DigitalDetox
• We STILL Don’t Understand Childbirth | Dr Jennifer Lincoln 30.04.2026 43min

  💬 Protecting first time parents from the realities of childbirth comes at a price. Not knowing how difficult it can be often leaves them unprepared - feeling guilty if it doesn’t go “perfectly”.⚡With all the misinformation around - and shockingly high maternal mortality rates in the US - Dr Jennifer Lincoln has decided to take childbirth into her own hands. The social media educator has just released The Birth Book: An OB-GYN’s Guide to Demystifying Labor and Delivery.🎧 Stay tuned to find out:➡ What a “normal” labour really looks like➡︎ What you can say “no” to during labour (Hint: anything)➡︎ The truth about epidurals, C-sections and natural birth➡︎ That children can be healthy no matter how childbirth goes➡︎ Why the US is the highest rich nation for maternal mortality➡︎ How 1 in 3 births cause psychological trauma for the mum#DrKaran, #Pregnancy, #BirthScience, #Labour, #BirthTrauma, #ChildbirthMyths #WomensHealth, #MedicalScience, #HealthEducation, #MythBustingDon't miss an episode! Subscribe NOW: https://www.youtube.com/@DrKaran?sub_confirmation=1 📕 Chapters(0:00) Introduction - We need to be realistic about childbirth(2:10) How should women really prepare for birth?(3:27) Are doctors good patients when it comes to childbirth?(5:16) What does a normal first time labour really look like?(7:11) How to know when it’s time to go to the hospital(8:28) Should you pack a hospital bag?(10:07) What it really means to induce labour(14:09) Is there a best birthing position?(16:37) What can you say “no” to?(18:54) How to tell the difference between optional and necessary interventions(20:23) How different is second time labour?(22:38) What to do when a baby’s breach(24:22) Why you shouldn’t feel guilty about an epidural(28:51) Does vaginal seeding help?(29:25) Conversations to have before labour starts(31:56) The problem of “maternity deserts” in the US(34:52) Why maternal mortality is so high in the US(35:57) Why do black women have the worst childbirth outcomes?(39:16) What to consider if you’re having a homebirth(40:09) Why traumatic births are much more common than we realise🚽 Discover Throne’s incredible new smart toilet device at http://thronescience.com 🤖 Discover my digital twin here: http://DrKaran.ai 🔥  Head to https://loamscience.com/ try LOAM - and get an additional 10% with code POD10.🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook 📕 Pre-order my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation?utm_source=linktree_profile_share&ltsid=472cbbde-00e2-42ab-8a3f-725656fab3a5🎙️ An OG Podcasts production.About Dr Karan:Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health.📱Connect with me:Instagram: https://www.instagram.com/drkaranrajan/   Facebook: https://www.facebook.com/DrKaranR/  TikTok: https://www.tiktok.com/@dr.karanr  X: https://twitter.com/drkaranrajan  Website: https://linktr.ee/ThisisVitalInformation
• The Truth About GLP-1s, Food Noise & Weight Loss Drugs: Dr Federica Amati 27.04.2026 52min

  GLP-1 weight loss drugs are changing medicine, but are we talking about them in the right way? In this episode, Dr Karan Rajan speaks with Dr Federica Amati about GLP-1s, food noise, metabolic health, appetite, gut health, muscle loss, side effects and why nutrition support matters.Dr Federica Amati explains why these medications should not be seen as simple “weight loss drugs”, how food noise differs from real hunger, and what people should know before, during and after GLP-1 treatment.📗 Pre-order Dr Federica's book 'The Appetite Reset' here: https://shor.by/fP5HIn this conversation, we cover:* Why diet remains one of the biggest drivers of chronic disease* What GLP-1s actually do beyond weight loss* The difference between homeostatic hunger, hedonic hunger and microbiome-driven hunger* Why food noise can dominate appetite and eating behaviour* How protein and resistance training can help protect muscle* Why micronutrients, fibre and hydration matter on GLP-1s* The risks of black market or poorly regulated weight loss injections* How gut health may influence appetite, side effects and long-term success* Why whole foods and nutrient density still matter mostChapters00:00 Preview: GLP-1s, food noise and diet01:18 Welcome and Dr Federica Amati introduction02:18 Why GLP-1s need lifestyle and nutrition support03:21 Diet, chronic disease and preventable deaths05:08 Who should be using GLP-1 medications?07:18 Why GLP-1s are metabolic health medications08:13 GLP-1s, the brain and food noise08:51 Homeostatic, hedonic and microbiome-driven hunger09:22 Internal vs external food noise11:37 Practical ways to reduce food noise13:40 Loam sponsor read14:39 Why digestion starts in the brain17:29 Fullness, stomach stretch and meal replacements19:47 GLP-1s, muscle loss, protein and resistance training21:02 Micronutrients, hydration and nutrient density24:06 Supplements and Mediterranean dietary patterns26:10 Body image, identity and emotional changes on GLP-1s28:34 Regulation, TikTok access and black market risks30:47 Gut microbiome, appetite and natural GLP-1 signalling42:31 Preparing your gut, managing side effects and final advice💩 Head to https://loamscience.com/products/loam-prebiotic-fiber-formula?utm_source=youtube&utm_medium=social&utm_campaign=drkaranexplores to try LOAM - and get an additional 10% with code POD10.💊 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe🚽 Discover Throne's incredible new smart toilet device at http://thronescience.com📘 For more useful science for your everyday life, grab my best selling book "This Book May Save Your Life": https://geni.us/DrKaranBook📕 Get my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation🤖 Discover my digital twin here: http://DrKaran.ai🧬 Sign up for my Microbiome Course waitlist: https://drkaran.kit.com/microbiome-course-waitlistAbout Dr Karan:Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health.📱Connect with me:Instagram: / drkaranrajanFacebook: / drkaranrTikTok: / dr.karanrX: / drkaranrajanWebsite: www.drkaranrajan.com#GLP1 #WeightLossDrugs #FoodNoise #GutHealth #MetabolicHealth
• How Can You Trust A Supplement Actually Works? | Dr Amine Zorgani 23.04.2026 29min

  💬 How can you tell if a supplement actually does what it promises to do? There are so many on the market that are underdosed, understudied and not backed up by science. So before you choose your next supplement - this is the data that should inform your decision.⚡When Dr Karan created LOAM, his aim was to create a fibre supplement backed up by clinically robust data. In this special episode, he outlines the lengthy process that went into making sure it actually delivers results.🎧 Stay tuned to find out:➡ What a preclinical study is - and why they are essential➡︎ How a study can actually show you what’s going on inside someone’s gut➡︎ Why propionate is so important for gut health - and how LOAM boosts it➡︎ Why LOAM produces less gas and bloating than other fibre supplements➡︎ What trials are coming in the future for LOAM  #DrKaran, #LOAM, #Supplements, #Microbiome, #Butyrate, #GutHealth, #MedicalScience, #HealthEducation, #MythBustingDon't miss an episode! Subscribe NOW: https://www.youtube.com/@DrKaran?sub_confirmation=1 📕 Chapters(0:00) Introduction - How to choose a supplement that works(0:41) Why preclinical studies are so important(4:27) The combination that creates gold standard results(8:14) How the LOAM preclinical study actually worked(11:44) Surprising results from the LOAM trials(14:02) The importance of the short-chain fatty acid propionate(17:43) Why LOAM produces results so quickly (20:02) Why supplements don’t impact all people the same(22:18) How LOAM produces less gas than other fibre supplements(25:36) Fibre fermentation💩 Head to https://loamscience.com/products/loam-prebiotic-fiber-formula?utm_source=spotify&utm_medium=podcast&utm_campaign=podcast_loam_clinical_trials🚽 Discover Throne’s incredible new smart toilet device at http://thronescience.com 🤖 Discover my digital twin here: http://DrKaran.ai 🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook 📕 Pre-order my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation?utm_source=linktree_profile_share<sid=472cbbde-00e2-42ab-8a3f-725656fab3a5🎙️ An OG Podcasts production.About Dr Karan:Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health.📱Connect with me:Instagram: https://www.instagram.com/drkaranrajan/   Facebook: https://www.facebook.com/DrKaranR/  TikTok: https://www.tiktok.com/@dr.karanr  X: https://twitter.com/drkaranrajan  Website: https://linktr.ee/ThisisVitalInformation
• The Secret To Reducing Arthritis in 8 Weeks... 20.04.2026 53min

  Sleepwalking into arthritis isn’t inevitable. And some changes can show up faster than most people expect.In this episode, Dr Karan Rajan speaks with Professor Tamiko Katsumoto about why arthritis rates are rising, the differences between rheumatoid arthritis and osteoarthritis, and what the best evidence says about reducing joint inflammation, including a lifestyle medicine intervention where benefits were seen as early as 8 weeks (with the primary endpoint at 16 weeks).This isn’t about “miracle cures.” It’s about stacking the odds in your favour: Diet quality, fibre, fermented foods, weight and metabolic health, sleep, stress, movement. And how these interact with inflammation, the gut, and joint symptoms.In this episode, we cover:∙ RA vs OA: Classic symptom patterns and why they’re treated differently∙ Why treatments for osteoarthritis can feel limited (and why lifestyle is still worth discussing)∙ “Food as medicine” and why joints are a symptom you can actually feel change∙ The “Plants for Joints” study: What changed at 8 weeks and what the 16-week endpoint showed∙ The gut-joint axis: Gut barrier, microbial diversity, and immune regulation∙ Why some patients flare on ultra high meat / fibre-free approaches (and what to do instead)∙ Practical “build my plate” guidance for joint and inflammation support#Arthritis #JointPain #RheumatoidArthritis #Osteoarthritis #Inflammation💩 Head to https://loamscience.com/products/loam-prebiotic-fiber-formula?utm_source=youtube&utm_medium=social&utm_campaign=drkaranexplores to try LOAM - and get an additional 10% with code POD10.💊 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe🚽 Discover Throne's incredible new smart toilet device at http://thronescience.com📘 For more useful science for your everyday life, grab my best selling book "This Book May Save Your Life": https://geni.us/DrKaranBook📕 Get my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation🤖 Discover my digital twin here: http://DrKaran.ai🧬 Sign up for my Microbiome Course waitlist: https://drkaran.kit.com/microbiome-course-waitlistAbout Dr Karan:Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health.📱Connect with me:Instagram: / drkaranrajanFacebook: / drkaranrTikTok: / dr.karanrX: / drkaranrajanWebsite: www.drkaranrajan.com
• How To Really Strengthen Your Pelvic Floor | Dr. Kelly (Peterson) Luithly 16.04.2026 36min

  💬 One majorly overlooked part of health is your pelvic floor. You may think it’s just a worry for women - but men need to train their pelvic muscles too. The question is, how?If you’re the type of person who spends a lot of time sitting all day, have ever experienced gut problems or back pain - or you just want to improve your physique - this one’s for you.⚡Dr Kelly Peterson is the master of pelvic floor exercises - and shares all her best techniques in this episode.🎧 Stay tuned to find out: ➡ The 3 types of people who need to work on their pelvic floor ➡︎ What the pelvic floor is actually doing day-to-day ➡︎ The difference between a weak and an overactive pelvic floor ➡︎ Why holding in your pee - and forcing out your poop - are big no-nos ➡︎ The exercises you can do - anywhere! - to strengthen your pelvic floor daily#DrKaran, #PelvicFloor, #PoopHealth, #GutHealth, #BackPain, #BreathingTechniques, #WomensHealth, #MensHealth, #MedicalScience, #HealthEducation, #MythBustingDon't miss an episode! Subscribe NOW: https://www.youtube.com/@DrKaran?sub_confirmation=1 📕 Chapters(0:00) Introduction(0:31) How do you train your pelvic floor?(2:47) What does the pelvic floor actually do day-to-day?(4:56) Difference between weak and overactive pelvic floor(9:03) Common pelvic floor problems in men(12:30) Big no-nos when you go for a poop(16:14) Breathing techniques to use on the loo(20:59) Should you worry about making sounds while on the toilet?(23:02) How to potty train kids and turn them into super poopers(28:34) Why you shouldn't pee ‘just in case’(31:05) Tips to improve your pelvic floor - wherever you are(33:29) How often should we do pelvic floor exercises?🚽 Discover Throne’s incredible new smart toilet device at http://thronescience.com 🤖 Discover my digital twin here: http://DrKaran.ai 🔥  Head to https://loamscience.com/ try LOAM - and get an additional 10% with code POD10.🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook 📕 Pre-order my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation?utm_source=linktree_profile_share&ltsid=472cbbde-00e2-42ab-8a3f-725656fab3a5🎙️ An OG Podcasts production.About Dr Karan:Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health.📱Connect with me:Instagram: https://www.instagram.com/drkaranrajan/   Facebook: https://www.facebook.com/DrKaranR/  TikTok: https://www.tiktok.com/@dr.karanr  X: https://twitter.com/drkaranrajan  Website: https://linktr.ee/ThisisVitalInformation
• The Menopause Symptoms We Keep Missing | Dr Louise Newson 13.04.2026 43min

  Most people can’t name five menopause symptoms beyond hot flushes and the biggest problem might start with the word itself. In this episode, Dr Karan Rajan speaks with Dr Louise Newson, a hormone and menopause specialist, about what’s actually happening biologically, why symptoms get missed or mislabelled, and how evidence, guidelines, and real-world prescribing shape care.In this conversation, we cover:Why “menopause” as a label can obscure the underlying hormone biologyThe three-hormone framework: Oestrogen, progesterone, testosteroneWhy symptoms like brain fog, mood changes, and gut symptoms can be misattributedBioidentical vs synthetic hormones (and why molecular structure matters)Osteoporosis risk, prevention, and what “healthy ageing” should includeDosing and absorption: Patches vs gels, and why some people need higher dosesWhy “guidelines” are a guide and where personalisation matters most🎬 Chapters 01:22 – Most people can’t name five symptoms beyond hot flushes01:56 – The definition problem: “A year without a period” doesn’t explain biology02:59 – Back to basics: oestrogen, progesterone, testosterone 04:24 – Is menopause “just ageing” or a treatable deficiency state? 06:21 – Misdiagnosis: IBS, brain fog, depression and missed hormone deficiency08:40 – Why “hard to measure” symptoms got ignored in research and guidelines09:04 – Hormones and inflammation: metabolic risk shifts in perimenopause10:32 – Osteoporosis risk and prevention: Why this matters clinically11:22 – Sponsor: Loam12:14 – Bioidentical vs synthetic hormones: The “key and lock” explanation14:59 – Contraindications and breast cancer conversations 17:12 – Guidelines vs optimisation: Why safe does not always mean best 18:31 – How to read guidelines: Who wrote them, conflicts, and cited studies20:18 – Dosing: “lowest effective dose” and why needs vary22:25 – Louise’s own dosing story: Symptom improvement within days24:14 – Absorption science: Skin variation and patch placement differences26:01 – When to consider hormones: Symptoms and quality-of-life impact27:18 – PMS and PMDD: Severe pre-period symptoms and hormone strategies28:58 – The timing hypothesis and what WHI got wrong 31:04 – The “stop at 60” myth, synthetic-hormone data, and fear headlines32:26 – The risks of not taking hormones34:07 – Sponsor: Throne35:11 – Gut microbiome and hormones: Reflux, bloating, and symptom shifts41:29 – Outcomes and personalisation: The metric is quality of life42:15 – Mental health outcomes discussion and clinic data💩 Head to https://loamscience.com/products/loam-prebiotic-fiber-formula?utm_source=youtube&utm_medium=social&utm_campaign=drkaranexplores to try LOAM - and get an additional 10% with code POD10.💊 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe🚽 Discover Throne's incredible new smart toilet device at http://thronescience.com📘 For more useful science for your everyday life, grab my best selling book "This Book May Save Your Life": https://geni.us/DrKaranBook📕 Get my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation🤖 Discover my digital twin here: http://DrKaran.ai🧬 Sign up for my Microbiome Course waitlist: https://drkaran.kit.com/microbiome-course-waitlistAbout Dr Karan:Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humour. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health.📱Connect with me:Instagram: / drkaranrajanFacebook: / drkaranrTikTok: / dr.karanrX: / drkaranrajanWebsite: www.drkaranrajan.com
• All Your GLP-1 Questions Answered (AMA with Dr Karan) 09.04.2026 38min

  💬 All your GLP-1 weight loss questions answered in this AMA with Dr Karan. Should you take them if you’re not overweight? Can you stay on them forever? How can you eat better when your appetite is gone?⚡ Answering the questions sent in by you, Dr Karan explains the science, benefits, risks and ethics of using drugs like Ozempic, Wegovy Mounjaro and Tirzepatide. 🎧 Stay tuned to find out: ➡ Whether BMI matters when you’re thinking about going on GLP-1s ➡︎ If it’s safe to stay on GLP-1s forever - and how to come off safely ➡︎ Are maintenance doses and microdosing effective? ➡︎ How weight loss drugs affect the gut microbiome ➡︎ What to eat to hit fibre, protein and calorie targets when you have no appetite ➡︎ How hormones and women’s health conditions are impacted ➡︎ Why GLP-1s benefits extend way beyond weight loss#DrKaran, #WeightLoss, #Ozempic, #Tirzepatide, #GutHealth, #GLP1, #AMA, #MedicalScience, #HealthEducation, #MythBustingDon't miss an episode! Subscribe NOW: https://www.youtube.com/@DrKaran?sub_confirmation=1 📕 Chapters(0:00) Introduction(1:10) What is a GLP-1 agonist?(2:00) Can fit people use Tirzepatide during a fat loss period to target visceral fat?(3:58) What BMI do you need to have?(5:22) Is everyone secretly on GLP-1s?(6:03) Using GLP-1s for food noise, even if not overweight?(8:00) Will the NHS soften the criteria for GLP-1s?(8:55) Can you stay on GLP-1s forever?(10:37) How to safely come off weight loss drugs(12:03) Can you stop food noise once you come off the drugs?(13:53) Are maintenance doses effective?(14:57) Is microdosing GLP-1s an option?(16:42) Short term vs long term side effects(19:10) Is nausea a permanent side effect of weight loss drugs?(20:16) Should you force yourself to eat?(22:51) How to deal with “Ozempic face”(24:13) Effect of GLP-1s on the gut microbiome(26:32) How to eat enough while working out when you have no appetite?(27:52) Can you build muscle on GLP-1s?(29:56) Are hormones affected by GLP-1s?(31:16) Can it help with endometriosis?(32:53) Why LOAM can help while using GLP-1s(34:29) Tips on high fibre, low calorie foods for GLP-1 users(35:30) Inflammation, heart health - and other benefits of GLP-1s🚽 Discover Throne’s incredible new smart toilet device at http://thronescience.com 🤖 Discover my digital twin here: http://DrKaran.ai 🔥  Head to https://loamscience.com/ try LOAM - and get an additional 10% with code POD10.🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook 📕 Pre-order my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation?utm_source=linktree_profile_share<sid=472cbbde-00e2-42ab-8a3f-725656fab3a5🎙️ An OG Podcasts production.About Dr Karan:Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health.📱Connect with me:Instagram: https://www.instagram.com/drkaranrajan/   Facebook: https://www.facebook.com/DrKaranR/  TikTok: https://www.tiktok.com/@dr.karanr  X: https://twitter.com/drkaranrajan  Website: https://linktr.ee/ThisisVitalInformation
• How to Fix Your Gut Health with Fibre! 06.04.2026 26min

  Most people are missing one of the most important nutrients for long-term health: fibre.In this solo episode, Dr Karan breaks down everything you need to know about fibre. From the cheapest ways to get more, to when you should eat it, and how it impacts your gut, cholesterol, metabolism, and long-term disease risk.What You’ll Learn:The cheapest high-fibre foods (and why beans dominate)When to eat fibre for maximum benefitHow fibre affects your gut microbiomeWhether fibre supplements are worth itHow much fibre you actually needWhy most people are under-consuming fibreThe science behind bloating and fibre adaptationHow fibre supports long-term health and disease preventionKey Insights from the Episode:“Your gut health and your microbiome health should not be compromised by your budget.”“If the goal is maximum fibre for the least amount of money, you're not going to find better than beans and legumes.”“The best time to take your fibre is basically whenever you remember to take your fibre.”“Only 5% of us are feeding our gut properly.”“I managed to reverse my high cholesterol… through increasing dietary fibre intake.”About Dr Karan:Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor.🚽 Discover Throne’s incredible new smart toilet device at http://thronescience.com 🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook 📕 Pre-order my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation?utm_source=linktree_profile_share&ltsid=472cbbde-00e2-42ab-8a3f-725656fab3a5🔥 Head to https://loamscience.com/ try LOAM - and get an additional 10% with code POD10.🤖 Discover my digital twin here: http://DrKaran.ai 📱Connect with me:Instagram: / drkaranrajanFacebook: / drkaranTikTok: / dr.karanrX: / drkaranrajanWebsite: www.drkaranrajan.com#GutHealth #Fibre#Microbiome #HealthScience #Nutrition
• The Biggest Myths About Exercise In Pregnancy | Dr Margie Davenport 02.04.2026 45min

  💬 Exercise during pregnancy is surrounded by myths, fear, and outdated advice. But the truth is staying active can be one of the most powerful things you can do for both you and your baby.⚡To unpack what safe, effective exercise really looks like during pregnancy and why misinformation is still so widespread - Dr Karan is joined by Dr Margie Davenport, professor and leading researcher in exercise during pregnancy. Whether you’re expecting, planning a pregnancy, or supporting someone who is, this conversation is essential listening.🎧 Stay tuned to find out: ➡ Why there’s so much confusion and misinformation around exercise in pregnancy➡︎ The science behind common myths about exercising while pregnant ➡︎ What “safe” exercise really looks like at each stage of pregnancy ➡︎ How physical activity benefits your baby’s health and development ➡︎ The role exercise plays in reducing the risk of serious complications ➡︎ Why outdated advice still persists in medical and public spaces ➡︎ How to approach exercise with confidence during pregnancy#DrKaran, #PregnancyHealth, #PrenatalFitness, #ExerciseDuringPregnancy, #WomensHealth, #MedicalScience, #HealthEducation, #MythBustingDon't miss an episode! Subscribe NOW: https://www.youtube.com/@DrKaran?sub_confirmation=1 📕 Chapters(0:00) Introduction - The biggest myth regarding exercise and pregnancy(1:00) Why exercise in pregnancy is surrounded by misinformation (2:05) What the evidence says (4:02) Exercise at different stages of pregnancy (6:00) The role of epigenetic factors(7:55) How exercise during pregnancy impacts a child's long-term health (11:00) Exercise and gestational diabetes and preeclampsia(12:03) How exercise affects labor outcomes(13:50) Walking or aerobic exercise versus strength training(16:50) The fear of miscarriage (18:57) Exercises pregnant women should definitely avoid (22:10) Weightlifting during pregnancy(24:03) Taking creatine and supplements during pregnancy(27:49) Optimal heart rate during pregnancy(30:03) Exercise and high risk pregnancies(33:02) How to conduct safe and ethical research in this area(36:00) How to exercise safely postpartum (41:00) Exercise and the gut microbiome(42:57) What Margie is researching next 🚽 Discover Throne’s incredible new smart toilet device at http://thronescience.com 🤖 Discover my digital twin here: http://DrKaran.ai 🔥  Head to https://loamscience.com/ try LOAM - and get an additional 10% with code POD10.🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook 📕 Pre-order my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation?utm_source=linktree_profile_share<sid=472cbbde-00e2-42ab-8a3f-725656fab3a5🎙️ An OG Podcasts production.About Dr Karan:Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health.📱Connect with me:Instagram: https://www.instagram.com/drkaranrajan/   Facebook: https://www.facebook.com/DrKaranR/  TikTok: https://www.tiktok.com/@dr.karanr  X: https://twitter.com/drkaranrajan  Website: https://linktr.ee/ThisisVitalInformation
• How Food Builds Your Brain: Cooking Special with The Brain Docs 30.03.2026 1val 15min

  Cooking isn’t just about flavour, it directly impacts your brain, gut, and heart health.In this special episode, Dr Karan teams up with The Brain Docs, Drs. Ayesha & Dean Sherzai, to cook a nutrient-dense curry while breaking down the real science behind food and its impact on your body. From fibre and omega-3s to anti-inflammatory ingredients and the gut-brain connection.Discussed in the episode: “the basic everyday food you eat literally makes your brain.” “what happens in your gut determines everything.”This is not about “superfoods”, it’s about dietary patterns, real ingredients, and how what you eat daily shapes your long-term health. What You’ll Learn:How food impacts brain function and mental healthWhy fibre is critical for your gut and brainThe truth about tofu, coffee, and mushroomsWhy “anti-inflammatory diets” actually matterThe gut-brain connection explained simplyHow cooking methods affect nutritionAnti-inflammatory curry pasteTofu (high-protein, low saturated fat)Fibre-rich vegetablesGinger, garlic, turmeric & spicesCashew cream alternative to coconut milk What We Cook:Anti-inflammatory curry pasteTofu (high-protein, low saturated fat)Fibre-rich vegetablesGinger, garlic, turmeric & spicesCashew cream alternative to coconut milkChapters:00:00:30 – Intro00:03:29 – “What happens in the gut determines everything”00:04:24 – Tofu as the protein + the soy myth00:06:51 – Coffee & cognition: What the data suggests 00:11:20 – Ginger for nausea & gut motility00:12:36 – Dietary patterns over single foods (Mediterranean-style pattern explained)00:16:55 – “Eat the rainbow”: Polyphenols, fibre types, carotenoids00:19:29 – Omega-3 index & omega-3s as brain building blocks00:20:19 – Omega-3 supplements: When it’s reasonable00:22:23 – Prevention & the “pillars” analogy for long-term brain health00:35:42 – Mental health & the gut: It’s multi-layered 00:36:24 – IBS: treating gut symptoms and mental health burden00:48:01 – Turmeric for brain health & research background 00:49:20 – Turmeric supplements: Why high-dose curcumin is different from food01:06:12 – “Taste and adjust”: The most important cooking step before serving01:08:55 – Basil at the end & final flavour check01:09:20 – Curry ready01:12:50 – Dessert reveal: Chia pudding with cashews & mango01:22:08 – Final thoughts
• Warning Signs of Endometriosis Doctors Miss (Carla Cressy’s Story) 23.03.2026 43min

  Endometriosis red flags are often missed, especially when symptoms look like IBS, bladder issues, or “normal” test results.In this episode of Dr Karan Explores, Dr Karan Rajan speaks with Carla Cressy about her lived experience of endometriosis, the long road to diagnosis, what severe disease can look like, and how to advocate for yourself when you’re being dismissed.In this conversation, we cover:Warning signs doctors often miss (bowel/rectal pain, bladder/UTI-like symptoms, bleeding after sex, severe fatigue)Why endometriosis can be mislabelled as IBS/IBDWhy normal blood tests/scans don’t necessarily rule endometriosis out — and what to do nextThe impact on mental health, work, relationships, and quality of lifeFertility and access: egg freezing, NHS gaps, and why pathways matterPractical advocacy: symptom diaries, bringing someone to appointments, asking for documentation, and next-step questions to move care forwardAbout Dr Karan: Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor.🚽 Discover Throne’s incredible new smart toilet device at http://thronescience.com 🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook 📕 Pre-order my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation?utm_source=linktree_profile_share&ltsid=472cbbde-00e2-42ab-8a3f-725656fab3a5🔥 Head to https://loamscience.com/ try LOAM - and get an additional 10% with code POD10.🤖 Discover my digital twin here: http://DrKaran.ai 📱Connect with me:Instagram: / drkaranrajanFacebook: / drkaranTikTok: / dr.karanrX: / drkaranrajanWebsite: www.drkaranrajan.com
• You’re Missing THIS About Eye Health | Dr Bryce Appelbaum 19.03.2026 42min

  💬 Vision and eyesight are two totally different things. And most of us are ignoring both! But improving your eye health is really easy when you know how. Not only can simple techniques help you stave off myopia, they can even improve your whole experience of the world.⚡To discuss the art of vision training - and why it’s so crucial for all of us - Dr Karan is joined by Dr Bryce Appelbaum, Neuro-optometrist and CEO of MyVisionFirst. Whether you want to optimise your vision, or correct annoying issues, this conversation is for you.🎧 Stay tuned to find out:➡ The difference between eyesight and vision - and why it’s important to separate them➡︎ How even “perfect” eyesight can be optimised➡︎ What screens are actually doing to our eyes➡︎ Simple exercises to reduce common eye problems➡︎ What happens when eye problems go unnoticed or are misdiagnosed➡︎ How vision problems can mimic symptoms of ADHD and dyslexia#DrKaran, #MedicalScience, #HealthEducation, #HealthTips, #MedicalScience, #EyeSight, #EyeCare, #VisionTraining, #EyeHealthDon't miss an episode! Subscribe NOW: https://www.youtube.com/@DrKaran?sub_confirmation=1 📕 Chapters(0:00) Introduction - The difference between “vision” and “eyesight”(1:25) The eye-brain connection(2:56) How vision is really measured(4:39) Bringing vision back to a 92-year-old(9:38) Can “perfect” eyesight may be hiding real problems(12:09) Why cases of myopia/nearsightedness is rising(15:10) How to alleviate damage from screen-time(17:44) Signs you eyes have had too much screens(20:12) Simple tricks to alleviate common eye problems(24:18) The problem of misdiagnosed vision problems(26:52) How vision problems can mimic symptoms of ADHD and dyslexia(32:24) How often kids’ vision problems are being missed(35:46) Other environmental issues that affect vision(39:25) Two things you should start today for better eye health🚽 Discover Throne’s incredible new smart toilet device at http://thronescience.com 🤖 Discover my digital twin here: http://DrKaran.ai 🔥  Head to https://loamscience.com/ try LOAM - and get an additional 10% with code POD10.🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook 📕 Pre-order my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation?utm_source=linktree_profile_share<sid=472cbbde-00e2-42ab-8a3f-725656fab3a5🎙️ An OG Podcasts production.About Dr Karan:Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health.📱Connect with me:Instagram: https://www.instagram.com/drkaranrajan/   Facebook: https://www.facebook.com/DrKaranR/  TikTok: https://www.tiktok.com/@dr.karanr  X: https://twitter.com/drkaranrajan  Website: https://linktr.ee/ThisisVitalInformation
• Can Psychedelics Reset a Depressed Brain? 16.03.2026 54min

  Can psilocybin treat depression within a day? In this episode, Dr Karan Rajan sits down with psychedelic researcher Dr Rayyan Zafar to break down the science of psilocybin, treatment-resistant depression, brain scans, microdosing, and whether psychedelic therapy could become a real part of mainstream mental health care.They explore why current antidepressants do not work for everyone, how psychedelics may affect the brain differently, what researchers are seeing on scans after a single dose, and why the conversation around psychedelic therapy is far more nuanced than internet hype suggests.In this episode:Why psychiatry needs new tools for depressionWhy SSRIs do not work for everyoneHow psilocybin interacts with serotonin receptorsThe idea of a “plastic window” after psychedelic therapyWhether psychedelics could help healthy people, not just patientsWhat the evidence says about microdosingThe real safety questions around psychedelic treatmentDMT, short-acting psychedelics, and where the field may go next00:00 - Welcome Dr Rayyan Zafar04:35 - How psychedelics work in the brain07:29 - Psychedelics, culture and meaning-making08:21 - What counts as treatment-resistant depression?15:26 - Could psychedelics become preventative medicine?17:20 - Depression, rumination and the default mode network20:37 - The “plastic window” and why therapy matters26:09 - The truth about Microdosing33:20 - Safety, screening and who should avoid psychedelics42:04 - DMT, ayahuasca and future treatments44:04 - Why short-acting psychedelics matterAbout Dr Karan:Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. 🚽 Discover Throne’s incredible new smart toilet device at http://thronescience.com🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook📕 Pre-order my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation?utm_source=linktree_profile_share&ltsid=472cbbde-00e2-42ab-8a3f-725656fab3a5🔥 Head to https://loamscience.com/ try LOAM - and get an additional 10% with code POD10.🤖 Discover my digital twin here: http://DrKaran.aiConnect with me:Instagram: / drkaranrajanFacebook: / drkaranTikTok: / dr.karanrX: / drkaranrajanWebsite: www.drkaranrajan.com#Psilocybin #MentalHealth #Neuroscience #PsychedelicTherapy #healthpodcast
• The Science of Eating at the Right Time | Adriano dos Santos 12.03.2026 49min

  💬 Health isn’t just about what you eat - it’s about when. Meal timing matters much more than you might realise. The same food eaten at different times can have wildly different effects on your body. ⚡To discuss the emerging field of chrononutrition, Dr Karan is joined by Adriano dos Santos - known as The Circadian Nutritionist. Together they explain how your organs and even your gut microbiome keep time - operating on a circadian clock!🎧 Stay tuned to find out:➡ How clock genes throughout our entire body impact our health➡︎ Why poor meal timing can create a lack of energy, sleep struggles and even IBS➡︎ How late nate phone scrolling isn’t as bad as you think➡︎ Why late night snacking and evening exercise confuses your body clock➡︎ Why not all fasting is created equal➡︎ Which foods and habits will improve your health and body clock the fastest#DrKaran, #MedicalScience, #HealthEducation, #HealthTips, #MedicalScience, #MealTiming, #ChronoNutrition, #CircadianNutrition, #DietTips, #GutHealth,Don't miss an episode! Subscribe NOW: https://www.youtube.com/@DrKaran?sub_confirmation=1 📕 Chapters(0:00) Introduction - Why chrono nutrition is so important for health(02:15) The health impacts of not paying attention to meal timing(04:46) How  butyrate interacts with your internal clock(06:56) What happens when your gut timing is out of sync(10:35) The gut clock’s role in sleep(14:37) How late night phone scrolling impacts your body clock(18:40) Should you avoid late night snacking?(21:58) How the same calories affect you differently depending on when you eat them(26:26) Should you eating your fibre earlier in the day?(31:19) Why fasting might not be as healthy as we thought(36:09) How body clock disruption could cause IBS(40:12) Specific food and habits to improve🚽 Discover Throne’s incredible new smart toilet device at http://thronescience.com 🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook 📕 Pre-order my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation?utm_source=linktree_profile_share🔥  Head to https://loamscience.com/ try LOAM - and get an additional 10% with code POD10.🤖 Discover my digital twin here: http://DrKaran.ai 🎙️ An OG Podcasts production.About Dr Karan:Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health.📱Connect with me:Instagram: https://www.instagram.com/drkaranrajan/   Facebook: https://www.facebook.com/DrKaranR/  TikTok: https://www.tiktok.com/@dr.karanr  X: https://twitter.com/drkaranrajan  Website: https://linktr.ee/ThisisVitalInformation
• The Best Sleep Schedule (According To Science) 09.03.2026 51min

  The best sleep schedule (according to science) isn’t just “8 hours”, it’s timing + consistency.In this episode, Dr Karan Rajan speaks with Professor Gina R. Poe about how to build a sleep schedule that supports deep sleep, REM sleep, memory, and long-term performance, using the levers that actually move the needle: consistent timing, light exposure, temperature, naps, and meal timing. In this conversation, we cover:Why sleep consistency is repeatedly linked with performance and healthier ageing outcomes A practical “best schedule” window (and why earlier sleep helps catch key deep-sleep biology) How light at night disrupts circadian timing (and why dim red light matters) Naps: when they help, and when they can backfire on night sleep Temperature and why overheating can reduce REM sleep Meal timing (“chrononutrition”) and why late meals can fragment sleep Plus: REM sleep, sleep spindles, memory, alcohol, and why some sedatives alter sleep architecture 🎬 Chapters01:03 – Introducing Professor Gina R. Poe 01:51 – REM sleep: remembering AND forgetting02:15 – Crick’s REM-for-forgetting hypothesis04:16 – Hippocampus → neocortex: how memories move during sleep06:06 – Stress “sweet spot” for learning (too little vs too much) 07:39 – Rats in space: learning in 3D/zero gravity11:26 – Locus coeruleus (“blue spot”): arousal, learning, and REM switching14:26 – Nightmares/PTSD: why REM needs the LC to go quiet17:33 – Alcohol + sedatives: how they can reduce spindles and REM 18:47 – Sleep architecture 101: cycles, deep sleep, REM, spindles 20:48 – Growth hormone timing + why circadian alignment matters 21:27 – “You can’t catch up”: why your body has a schedule 23:17 – Transition into REM: spindles, K-complexes, P-waves 25:53 – How to increase spindles: learning something new 27:32 – What reduces spindles: sleeping pills/benzos/alcohol 28:29 – Wearables vs EEG: what tracking can and can’t tell you 31:27 – Wearables + alcohol effects + women & temperature tracking 33:19 – Hormones & sleep: what we know, what’s inconclusive (and why) 36:59 – New parents: shifts, feeding timing, and protecting circadian rhythm 40:15 – Night feeds: don’t turn on bright lights (use dim red light) 41:29 – The best sleep schedule (science-based): consistency + timing 43:38 – Naps: when they help and when they hurt bedtime 44:42 – Temperature: why overheating can reduce REM sleep 47:28 – Meal timing: avoid late meals + use meals to reset jet lag 49:16 – The research gap: women’s cycles, diaries, and better studies 🚽 Discover Throne’s incredible new smart toilet device at ⁠http://thronescience.com⁠🔥 Try LOAM and get an additional 10% with code POD10: https://loamscience.com/products/loam-prebiotic-fiber-formula?utm_source=youtube&utm_medium=social&utm_campaign=drkaranexplores🔥 Get my free weekly newsletter filled with easy-to-action health tips and science: ⁠https://drkaran.beehiiv.com/subscribe⁠🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: ⁠https://geni.us/DrKaranBook⁠📕 Pre-order my new book, This Is Vital Information: ⁠https://linktr.ee/ThisisVitalInformationAbout Dr Karan:Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor.📱Connect with me:Instagram: / drkaranrajanFacebook: / drkaranTikTok: / dr.karanrX: / drkaranrajanWebsite: www.drkaranrajan.com#SleepScience #CircadianRhythm #SleepSchedule #REMSleep #DeepSleep