Theory of Change
Theory of Change is a podcast about the future of global development — and the people trying to reshape it.<br /><br />Hosted by Devex Senior Reporter Michael Igoe, the show features candid conversations with leaders in philanthropy, foreign policy, technology, finance, media, and humanitarian aid about the forces transforming how global change actually happens: power, politics, money, influence, and ideas.<br /><br />Not a panel. A conversation with a real person.<br /><br />Episodes are published every Tuesday.<br /><br />Subscribe to our YouTube channel:<br /><a href="https://www.youtube.com/@devex" target="_blank" rel="noreferrer noopener">https://www.youtube.com/@devex</a><br /><br />The podcast is produced by Devex Associate Editor Thomas Cserép and Mai Ylagan.
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How Alexander Berger weighs the world’s biggest problems 02.06.2026 1ч 6минCoefficient Giving, one of the world’s largest effective-giving funders, is about to go even bigger.On the heels of its biggest funding year ever in 2025 — in which it channeled over $1 billion to highest-impact causes — the organization formerly known as Open Philanthropy and funded by Facebook cofounder Dustin Moskovitz and his wife Cari Tuna is eyeing annual growth upward of 50% and bringing on more staff to get it done.The person behind that vision is Alexander Berger, Coefficient Giving’s cofounder and CEO. Berger is in charge of turning Facebook wealth — and, increasingly, funds from other donors — into as many lives saved and improved as possible. The organization is a major funder in global health and development, catastrophic risk, research and innovation, and even farm animal welfare.Last week, Coefficient Giving launched a new pooled fund to tackle Group A Streptococcus — an easily treated disease that is still responsible for nearly 700,000 deaths a year — a cause that reflects the organization’s framework for tackling problems that are important, neglected, and tractable.In a rare, in-depth interview with Devex Senior Reporter Michael Igoe, Berger sheds light on Coefficient Giving’s rapid growth plans, its strategy for choosing high-impact causes, the rise of artificial intelligence philanthropy, and his own approach to affecting change in an uncertain world.This is the first episode of Theory of Change, a new podcast series from Devex featuring candid interviews with leaders shaping the future of global development.
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