Oncology Today with Dr Neil Love

Епизоди

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  Antibody-Drug Conjugates for Multiple Myeloma — An Interview with Dr Douglas W Sborov 23.09.2026 49мин

  Featuring an interview with Dr Douglas W Sborov, including the following topics:DREAMM-2 trial outcomes and clinical development of antibody-drug conjugates for multiple myeloma (MM); mechanism of action of belantamab mafodotin (belamaf) and predictors of response to treatment (0:00)Perspectives on findings from the Phase III DREAMM-7 trial of belamaf combined with bortezomib/dexamethasone for relapsed/refractory MM (4:26)Progression-free survival estimates with current quadruplet induction and maintenance regimens for newly diagnosed MM (6:36)Phase I DREAMM-9 trial and ongoing evaluation of belamaf in the up-front setting (11:48)Potential integration of belamaf into the relapsed/refractory and newly diagnosed MM treatment settings (16:00)Prevention and management of ophthalmic events related to treatment with belamaf (21:27)Case: A man in his mid 60s with multiregimen-recurrent MM receives single-agent belamaf (27:49)Case: A woman in her early 70s with recurrent t(11;14) MM and disease progression on single-agent belamaf experiences a sustained response to talquetamab (33:27)Case: A man in his early 70s with heavily pretreated MM receives belamaf with bortezomib (39:53)CME information and select publications
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  Metastatic Triple-Negative Breast Cancer — 5-Minute Journal Club Activity 2 with Dr David W Cescon 22.09.2026 23мин

  Featuring perspectives from Dr David W Cescon, including the following topics:Clinical treatment of BRCA-mutated metastatic triple-negative breast cancer (0:00)CNS activity of TROP2-directed antibody-drug conjugates (5:36)Autoimmune considerations with immunotherapy (10:09)Treatment of oligoprogressive advanced breast cancer (17:31)CME information and select publications
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  Metastatic Triple-Negative Breast Cancer — 5-Minute Journal Club Activity 1 with Dr David W Cescon 21.09.2026 29мин

  Featuring perspectives from Dr David W Cescon, including the following topics:First-line treatment of metastatic triple-negative breast cancer (mTNBC) in patients not eligible for immunotherapy (0:00)First-line treatment of mTNBC in patients eligible for immunotherapy (12:05)Adverse events (19:39)CME information and select publications
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  Gynecologic Cancers — Reviewing Key Presentations from the 2026 ASCO Annual Meeting 17.09.2026 58мин

  Featuring perspectives from Dr Gottfried E Konecny and Dr Brian M Slomovitz, including the following topics:Introduction (0:00)Preventing Ovarian Cancer (1:04)Endometrial Cancer (5:27)Ovarian Cancer (25:36)Cervical Cancer (54:04)CME information and select publications
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  Metastatic Bladder Cancer — Rapid Case Review Issue 8 16.09.2026 25мин

  Featuring perspectives from Dr Alexandra Drakaki, including the following topics:Case: A man in his late 70s with diabetes and metastatic bladder cancer achieves radiographic response with enfortumab vedotin (EV) and pembrolizumab but develops uncontrolled hyperglycemia (0:00)Case: A man in his early 70s with muscle-invasive bladder cancer receives adjuvant nivolumab and experiences metastatic progression after 9 cycles of therapy (6:23)Case: A woman in her early 70s with Lynch syndrome and metastatic upper tract bladder cancer receives EV/pembrolizumab and develops myasthenia gravis (13:59)Case: A woman in her late 40s with FGFR3 mutant metastatic bladder cancer receives erdafitinib and experiences rising serum phosphate levels (20:04)CME information and select publications
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  Metastatic Bladder Cancer — Rapid Case Review Issue 7 16.09.2026 36мин

  Featuring perspectives from Dr Alexandra Drakaki, including the following topics:Case: A man in his early 80s with bladder cancer and metastatic progression in the viscera and lymph nodes receives enfortumab vedotin (EV) with pembrolizumab — Part 1 (0:00)Case: A man in his early 80s with metastatic bladder cancer achieves a complete response with EV/pembrolizumab therapy but develops gastrointestinal toxicity — Part 2 (5:37)Case: A man in his early 50s with metastatic bladder cancer receives second-line EV monotherapy intermittently (15:09)Case: A woman in her mid 60s with bladder cancer and a history of rheumatoid arthritis develops oligometastatic progression in the lung and receives EV monotherapy (21:03)Case: A man in his mid 80s with HER2-positive (IHC 3+) metastatic bladder cancer receives trastuzumab deruxtecan and develops ground glass opacities in his lungs concerning for pneumonitis (30:43)CME information and select publications
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  Breast Cancer — Reviewing Key Presentations from the 2026 ASCO Annual Meeting 15.09.2026 1ч 29мин

  Featuring perspectives from Dr Aditya Bardia, Dr Kevin Kalinsky and Dr Joyce O'Shaughnessy, including the following topics:Introduction (0:00)Hormone Receptor-Positive Breast Cancer — Dr Kalinsky (1:18)HER2-Positive Breast Cancer — Dr Bardia (42:46)Triple-Negative Breast Cancer — Dr O'Shaughnessy (1:01:41)CME information and select publications
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  Low-Grade Serous Ovarian Cancer — Rapid Case Review: Microlearning Activity 2 14.09.2026 26мин

  Featuring perspectives from Dr Rachel N Grisham, including the following topics:Case: A woman in her early 40s with recurrent low-grade serous ovarian cancer (LGSOC) and prior treatment with a MEK inhibitor receives avutometinib/defactinib on the RAMP 301 trial (0:00)Case: A woman in her early 70s with recurrent KRAS-mutated LGSOC receives avutometinib/defactinib and develops muscle weakness (10:03)Case: A woman in her late 70s with KRAS-mutated recurrent LGSOC develops congestive heart failure on trametinib and then receives avutometinib/defactinib (16:15)Case: A woman in her mid 60s with recurrent BRAF V600E LGSOC has concerns about side effects and receives single-agent dabrafenib (19:49)CME information and select publications
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  Low-Grade Serous Ovarian Cancer — 5-Minute Journal Club: Microlearning Activity 1 13.09.2026 28мин

  Featuring perspectives from Dr Rachel N Grisham, including the following topics:Mechanism, clinical evidence and practical use of avutometinib with defactinib for recurrent low-grade serous ovarian cancer (LGSOC) (0:00)A Phase III trial of letrozole alone as front-line treatment for LGSOC (11:11)Current and future role of avutometinib with defactinib for LGSOC (19:23)A Phase II/III trial of trametinib for recurrent LGSOC: Biomarker analyses and clinical implications (21:37)CME information and select publications
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  Chronic Myeloid Leukemia — An Interview with Prof Andreas Hochhaus 11.09.2026 59мин

  Featuring an interview with Prof Andreas Hochhaus, including the following topics:Biology of chronic myeloid leukemia (CML) and rationale for current therapeutic approaches; importance of cytogenetic testing (0:00)Mechanistic differences among first-generation tyrosine kinase inhibitors (TKIs), second-generation TKIs and asciminib (6:09)Potential mechanisms of adverse events documented with TKIs (10:23)Recent survey of patients with CML regarding goals of therapy and clinical implications; considerations for discontinuation of therapy (16:23)Comparative tolerability of asciminib and other agents used to manage CML; promoting adherence to treatment plans for patients (27:14)Comparative efficacy of asciminib and other agents used to treat CML (40:01)Potential areas for improvement in community oncology practice patterns; family planning in the context of CML treatment (43:53)Practical care strategies for CML patients; future developments (52:32)CME information and select publications
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  Endometrial Cancer — Microlearning Activity 3: Proceedings from an Independent Satellite Symposium during the SGO Annual Meeting on Women's Cancer 11.09.2026 20мин

  Featuring perspectives from Dr Floor J Backes, Dr Matthew A Powell and Dr Ritu Salani, moderated by Dr Salani, including the following topics:Case: A woman in her late 60s with recurrence of metastatic estrogen receptor-positive endometrial cancer enrolls in a trial of CDK4/6 inhibition with an aromatase inhibitor 1 year into maintenance dostarlimab after carboplatin/paclitaxel/dostarlimab and has no evidence of disease 3 years later (0:00)Adding a PARP inhibitor to immunotherapy and chemotherapy: The RUBY Part 2 and DUO-E trials (10:03)CME information and select publications
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  Non-Small Cell Lung Cancer — Targeting KRAS G12C 10.09.2026 57мин

  Featuring perspectives from Prof Solange Peters and Dr Joshua K Sabari, including the following topics:Introduction (0:00)Best Option for Your Patient (1:28)Biological Considerations (6:26)KRAS G12C Inhibitors (11:33)Second-Line Treatment (13:02)Current Clinical Trials in the First-Line Metastatic Setting (32:18)Current Clinical Trials in the Localized Setting (49:52)Current Clinical Trials with New Treatment Combinations and Agents (53:51)CME information and select publications
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  Prostate Cancer — The Optimal Use of Hormonal Therapy 08.09.2026 59мин

  Featuring perspectives from Dr William K Oh and Dr Mary-Ellen Taplin, including the following topics:Introduction: Another Perspective on the Treatment of Localized Prostate Cancer (0:00)Nonmetastatic Disease (10:32)Metastatic Androgen Pathway Modulation-Naïve and Androgen Pathway Modulation-Sensitive Disease (41:50)CME information and select publications
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  Chronic Lymphocytic Leukemia — Rapid Case Review: Microlearning Activity 4 07.09.2026 30мин

  Featuring perspectives from Prof John Seymour and cases from Dr Daniel Ermann, Dr Shazia Nakhoda and Dr Mahesh Swaminathan, including the following topics:Case: A woman in her mid 50s with multiple sclerosis, hypertension, IGHV-unmutated chronic lymphocytic leukemia (CLL) with an SF3B1 mutation and autoimmune hemolytic anemia receives acalabrutinib/venetoclax/obinutuzumab (0:00)Case: A man in his late 60s with bulky CLL diagnosed abroad receives zanubrutinib monotherapy (12:48)Case: A man in his late 40s with IGHV-mutated, del(13q) CLL with worsening symptoms and diffuse adenopathy after 1 year of observation receives venetoclax/obinutuzumab and attains a complete response (21:29)CME information and select publications
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  Chronic Lymphocytic Leukemia — 5-Minute Journal Club: Microlearning Activity 3 06.09.2026 22мин

  Featuring perspectives from Prof John Seymour, including the following topics:Safety of fixed-duration acalabrutinib/venetoclax for chronic lymphocytic leukemia (CLL) (0:00)Venetoclax re-treatment and ongoing trials with acalabrutinib/venetoclax for CLL (6:21)First-line treatment with sonrotoclax and zanubrutinib for CLL (13:10)CME information and select publications
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  AKT Inhibition in Prostate Cancer — Microlearning Activity 3: Proceedings from a Session Held Adjunct to the 2026 ASCO GU Cancers Symposium 05.09.2026 17мин

  Featuring perspectives from Dr Karim Fizazi, Dr Daniel George and Dr Elisabeth I Heath, moderated by Dr Heath, including the following topics:Tolerability of capivasertib and management of associated side effects — Question from Neeraj Agarwal, MD, FASCO (0:00)Case: A man in his early 70s with Type 2 diabetes presents with metastatic hormone-sensitive prostate cancer with widespread bone metastases and PTEN deficiency on next-generation sequencing and receives relugolix/darolutamide — Rana R McKay, MD, FASCO (8:39)CME information and select publications
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  ER-Positive, HER2-Positive Metastatic Breast Cancer — Patterns of Care Among Community Oncologists 03.09.2026 58мин

  Featuring perspectives from Dr Lisa A Carey and Dr Maha Hussain, including the following topics:Introduction (0:00)HER2 History (1:32)Cases from the GMO Survey (7:06)Biology and Selection of First-Line Therapy for HR-Positive, HER2-Positive Metastatic Breast Cancer (mBC) — Dr Mahtani (19:56)Faculty Case Presentations (31:37)Patterns of Care Survey — Part 1 (38:26)Optimizing the Use of Up-Front Maintenance Therapy for HER2-Positive mBC — Dr Carey (44:53)Faculty Case Presentations (54:13)CME information and select publications
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  Relapsed/Refractory Chronic Lymphocytic Leukemia — A Grand Rounds Program 02.09.2026 58мин

  Featuring perspectives from Dr William G Wierda, including the following topics:Introduction: Overview of the Grand Rounds Chronic Lymphocytic Leukemia Initiative (0:00)Sequencing Road Map (12:39)Key Datasets — Pirtobrutinib (21:08)Investigator Survey (34:09)Chimeric Antigen Receptor T-Cell Therapy (45:08)Other Novel Therapy Approaches (49:58)EHA 2026 (54:45)CME information and select publications
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  Lambert-Eaton Myasthenic Syndrome in Small Cell Lung Cancer — An Interview with Prof Ticiana Leal 01.09.2026 54мин

  Featuring an interview with Prof Ticiana Leal, including the following topics:Pathophysiology and clinical signs and symptoms (0:00)Screening and/or diagnostic approaches (5:45)Potential impact of available therapies for small cell lung cancer (SCLC) on paraneoplastic syndromes (7:36)Key clinical trial data for amifampridine and practicalities of its administration (14:05)Building awareness among patients, caregivers and the oncology community (22:37)Role of pyridostigmine in managing Lambert-Eaton myasthenic syndrome (LEMS); potential integration of EMG (electromyography) into monitoring (25:35)Case: A man in his early 70s who receives a diagnosis of limited-stage SCLC (LS-SCLC) with LEMS and undergoes treatment (27:41)Case: A woman in her late 70s already diagnosed with LS-SCLC who is subsequently evaluated and treated for LEMS (37:55)Current research and potential developments in the treatment of SCLC (48:32)CME information and select publications
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  For Oncology Nurses: Prostate Cancer — Proceedings from the 2026 Annual ONS Congress 31.08.2026 1ч 28мин

  Featuring perspectives from Mr Michael Lai, Dr Scott T Tagawa, Ms Stacy E Walker and Dr Evan Y Yu, moderated by Dr Tagawa, including the following topics:Introduction (0:00)Overview of Prostate Cancer (3:00)Hormonal Therapy for Nonmetastatic and Metastatic Hormone-Sensitive Prostate Cancer (HSPC) (6:12)Potential Role of Capivasertib in Metastatic HSPC (27:22)Current and Potential Future Role of PARP Inhibitors in Metastatic PC (46:39)Current and Future Role of Lutetium Lu 177 Vipivotide Tetraxetan for Patients with Metastatic PC (1:09:14)CME information and select publications