Around the Rheum with Drs. Daniel Ennis & Janet Pope

Episod

• Episode 61: A Living Legend - Dr. Proton Rahman, Member of the Order of Canada 22.05.2026 39min

  In this episode, Dr. Proton Rahman reflects on his journey from patient with spondyloarthritis to internationally recognized rheumatologist and newly appointed member of the Order of Canada. He shares how his lived experience shapes his approach to patient care, offering insight into empathy, trust, and connection in chronic disease management.Dr. Rahman also discusses the influence of key mentors — including Dr. Dafna Gladman, herself an Officer of the Order of Canada — in shaping his path into research and his work in the genetics of psoriatic arthritis and beyond! The conversation highlights the shift toward polygenic risk and the ongoing challenge of translating genetic discoveries into clinical practice.Looking ahead, Dr. Rahman explores the future of rheumatology, emphasizing precision medicine, improved diagnostics, and more effective use of existing therapies. A thoughtful discussion on humility, mentorship, and the evolving complexity of modern rheumatology.Dr. Proton Rahman is Clinical Chief of Rheumatology at Newfoundland and Labrador Health Services and John Lewis Distinguished Professor at Memorial University. A global expert in spondyloarthritis and psoriatic arthritis, his research focuses on the genetics of inflammatory arthritis and its translation into improved patient care. He is a recent appointee as a Member of the Order of Canada.Around The Rheum is produced by the CRA Communications Committee. A special thank you to the podcast team, Dr. Dax G. Rumsey (CRA Communications Committee Chair), Dr. Daniel Ennis (Host), Dr. Janet Pope (Host) David McGuffin (exploreproductions.ca),and Erin Stewart (CRA) for leading production.Our theme music was composed by Aaron Fontwell.For more on the work of the Canadian Rheumatology Association, visit rheum.ca
• Episode 60: ASM Roundup - Day 3 with Dr. Marinka Twilt and Dr. Mo Osman 18.04.2026 19min

  Hosts: Dr. Daniel Ennis, Dr. Janet PopeGuests: Dr. Marinka Twilt (Pediatric Rheumatologist, University of Calgary; ASM Program Committee Chair), Dr. Mo Osman (University of Alberta; Abstract Chair & ASM Planning Committee Co-Chair)We’re coming to you almost live from Halifax for Day 3—the final day of the Canadian Rheumatology Association ASM. The day featured strong podium presentations, a high-yield state-of-the-art lecture on Still’s disease, and a powerful closing keynote on health equity.Podium sessions highlighted emerging science across the spectrum, including sex-based differences in psoriatic arthritis linked to genetic and epigenetic factors, novel monogenic variants in pediatric lupus with neurocognitive involvement, and ongoing inequities in access to therapies for JIA across provinces.The state-of-the-art lecture on Still’s disease emphasized its spectrum across pediatric and adult care, with practical treatment strategies and increasing recognition of associated interstitial lung disease. Key points included the role of HLA-DRB1*15 as a risk marker, the importance of early treatment, and the potential for IL-1 and IL-6 therapies to contribute to complications in select patients.Workshops reinforced these themes, focusing on practical approaches to diagnosing and managing Still’s disease, including lung involvement and the role of JAK inhibitors in refractory cases.The meeting closed with a distinguished investigator lecture from Dr. Cheryl Barnabe, highlighting inequities in care for Indigenous populations and the importance of culturally safe, community-based care to address both geographic and systemic barriers.Main TakeawaysGenetic and epigenetic factors may explain sex differences in psoriatic arthritis Monogenic variants continue to reveal complexity in pediatric lupus Significant inequities persist in access to therapies for JIA across provinces Still’s disease spans pediatric and adult care with shared mechanisms HLA-DRB1*15 may help predict lung complications in Still’s disease Culturally safe, community-based care is essential to improving health equityWhat’s NextCRA ASM 2026 will be held in Vancouver.More highlights coming next year—see you in Vancouver!
• Episode 59: ASM Roundup - Day 2 with Dr. Marinka Twilt and Dr. Mo Osman 17.04.2026 26min

  Hosts: Dr. Daniel Ennis, Dr. Janet PopeGuests: Dr. Marinka Twilt (Pediatric Rheumatologist, University of Calgary; ASM Program Committee Chair), Dr. Mo Osman (University of Alberta; Abstract Chair & ASM Planning Committee Co-Chair)We’re coming to you almost live from Halifax for Day 2 of the Canadian Rheumatology Association ASM. The day featured diverse podium science, practical workshops, and a lively Great Debate on DMARD tapering.Podium sessions highlighted lupus research on cancer risk, rising costs and work disability in RA, and new biologic insights into flares, with B-cell changes supporting patient-reported disease activity in lupus.Workshops focused on practical tools, including capillaroscopy for early CTD detection, pediatric updates on neonatal lupus risk (anti-Ro vs anti-La), and a structured lab-based approach to unexplained lymphadenopathy.The Dunlop-Dottridge Lecture reviewed statin-associated myositis, emphasizing delayed onset, persistence after discontinuation of the statins, and early IVIG-based treatment.The Great Debate explored DMARD tapering, reinforcing that while guidelines are cautious, real-world care requires shared decision-making and a focus on the lowest effective dose rather than full discontinuation.Main TakeawaysRising costs and ongoing work disability remain significant in RAPatient-reported flares have a clear biological basisStatin-associated myositis can occur years after statin use and requires early IVIGDMARD tapering should be individualized, with focus on lowest effective doseWhat to Watch for on Day 3State-of-the-art lecture on Still’s disease across the lifespanMore high-impact podium presentationsClinical workshops, including one on topical therapiesGala dinner and closing eventsMore highlights coming tomorrow—stay tuned!
• Episode 58: ASM Roundup - Day 1 with Dr Marinka Twilt 16.04.2026 23min

  Hosts: Dr. Daniel Ennis, Dr. Janet PopeGuest: Dr. Marinka Twilt (Pediatric Rheumatologist, University of Calgary; ASM Program Committee Chair)We’re coming to you almost live from Halifax for Day 1 of the Canadian Rheumatology Association ASM. The day featured key updates across the field, including gaps in pediatric trials, growing recognition of autoinflammatory diseases, and the expanding role of genetics.The SELECT-GCA trial reinforced that upadacitinib is effective for both induction and maintenance of Giant Cell Arteritis (GCA), with high relapse rates after stopping—supporting longer-term treatment. In pediatric ANCA vasculitis, rituximab showed similar efficacy to cyclophosphamide with a safer profile.Sessions on “tough-to-treat RA” highlighted how often non-inflammatory factors drive symptoms, while Clinical Pearls and Medical Mysteries emphasized revisiting diagnoses and the importance of pathology and genetics.The keynote by Dr. Elizabeth Volkman rounded out the day with a focus on holistic care and patient empowerment. Main TakeawaysGCA likely requires longer-term therapy to prevent relapseRituximab is a safe, effective alternative in pediatric ANCA vasculitis“Tough-to-treat RA” often reflects non-inflammatory diseaseReassess when treatments fail—diagnosis evolvesGenetics and pathology are increasingly central to complex casesHolistic care and patient empowerment matter for outcomesWhat to Watch on Day 2New myositis insights, including statin-associated diseasePodium presentations showcasing emerging researchHands-on workshops (including TMJ)Poster tours, with a focus on trainee workThe Great Debate: “Be it resolved that medications should be tapered in patients with inflammatory arthritis in remission.”More highlights coming tomorrow—stay tuned!
• Episode 57: Autoinflammatory Diseases with Adult Rheumatologist Dr. Jason An 31.03.2026 40min

  Autoinflammatory diseases are often considered rare — but, in clinical practice, they may be far more common than we think. In this episode of Around the Rheum, hosts Dr. Daniel Ennis and Dr. Janet Pope speak with Dr. Jason An, a Toronto rheumatologist with expertise in autoinflammatory disorders.Together, they explore how these conditions differ from classic autoimmune disease, why adult rheumatologists should be thinking about them more often, and how to approach diagnosis when the presentation doesn’t fit neatly into familiar categories.Dr. An also shares practical strategies for recognizing autoinflammatory patterns, interpreting genetic testing, and using targeted therapies both diagnostically and therapeutically.In this episode we discuss:The evolving definition of autoinflammatory disease and how it differs from autoimmune diseaseWhy these disorders are not just pediatric diseases and may present in adulthoodA practical cytokine-based framework for classifying autoinflammatory diseasesThe four major inflammatory “buckets”:IL-1–mediated diseasesIL-18-mediated diseasesTNF / NF-κB pathway disordersInterferonopathiesClinical pattern recognition in patients with recurrent fevers and systemic inflammationThe role and limitations of genetic testing in autoinflammatory diseaseWhy variants of uncertain significance (VUS) may still be clinically meaningful in adultsUsing targeted therapies as diagnostic tools (colchicine, IL-1 blockade, JAK inhibitors)When rheumatologists should consider referral to an autoinflammatory disease specialistRecommended reading:Dr. An’s review on autoinflammatory diseases in The Journal of Rheumatology:https://www.jrheum.org/content/51/9/848Dr. Jason An, MD, MSc is an adult rheumatologist specializing in the diagnosis and treatment of autoinflammatory diseases who works in community practice in the Greater Toronto Area (GTA)Around The Rheum is produced by the CRA Communications Committee. A special thank you to the podcast team, Dr. Dax G. Rumsey (CRA Communications Committee Chair), Dr. Daniel Ennis (Host), Dr. Janet Pope (Host) David McGuffin (exploreproductions.ca), and Erin Stewart (CRA) for leading production.Our theme music was composed by Aaron Fontwell.For more on the work of the Canadian Rheumatology Association, visit rheum.ca
• Episode 56: What do rheumatologists get wrong about skin? Exploring the world of the Combined Rheumatology-Dermatology Clinic with Dr. Sheila Au and Dr. Kam Shojania 27.02.2026 56min

  Dr. Kam Shojania is a Clinical Professor at the University of British Columbia, Head of Rheumatology at Vancouver General Hospital, and Medical Director of the Mary Pack Arthritis Program. He co-leads the DART Clinic at St. Paul's Hospital, a combined dermatology-rheumatology clinic focused on complex inflammatory skin and connective tissue diseases. Dr. Sheila Au is a Clinical Professor in the Department of Dermatology and Skin Science at the University of British Columbia and a medical dermatologist at St. Paul’s Hospital. She co-leads the DART Clinic and specializes in inflammatory and autoimmune skin disease, with a focus on morphology-based diagnosis and collaborative care.
• Episode 55: Exploring the New CRA/CanRIO Guidelines with Dr. Carrie Ye and Dr. Jeff Graham 04.12.2025 32min

  A must-listen for anyone treating autoimmune disease or cancer in the era of immunotherapy.
• Episode 54: Santé planétaire et durabilité en rhumatologie avec Dres Stephanie Tom et Elizabeth Hazel 16.10.2025 23min

  Dans cet épisode d’Autour de la Rhumato, le Dr Hugues Allard-Chamard discute de la santé planétaire et des moyens d’intégrer la durabilité dans la pratique médicale avec les Dres Stéphanie Tom et Elizabeth Hazel.
• Episode 53: Rheumatology and Planetary Health with Dr. Stephanie Tom 16.10.2025 44min

  Did you know that the healthcare industry has a bigger climate change footprint than the airline industry? In this episode of 'Around the Rheum,' hosts Dr. Daniel Ennis and Dr. Janet Pope join in conversation about how rheumatologists can help fight global warming with Dr. Stephanie Tom, the Rheumatology Division Head at Trillium Health Partners in Mississauga, ON and Vice President of the Canadian Rheumatology Association (CRA).
• Episode 52: Medical Mysteries #5 - Young man with unexplained weight gain and shortness of breath with Dr. Steven Rowe 04.09.2025 1j 10min

  A challenging case from Newfoundland featuring a 22-year-old male with severe fatigue, weight gain, requiring a wheelchair and who had to stop his studies and move back with his parents.
• Episode 51: The Past, Present and Future of Psoriatic Arthritis with Dr. Dafna Gladman, Officer of the Order of Canada 16.07.2025 39min

  Dr. Gladman is an Emeritus Professor of Medicine at the University of Toronto and and Emeritus Scientist at the Schroeder Arthritis Institute and Crumble Research Institute.
• Episode 50: Exploring Large-Vessel Vasculitis (LVV) with Dr. Alison Clifford 22.05.2025 38min

  Dr. Alison Clifford is a rheumatologist and associate professor in the faculty of medicine at the University of Alberta. She has a research and clinical focus on Vasculitis, particularly giant cell arteritis. And she is an associate member of CanVasc.
• Episode 49: Medical Mysteries #4 - Unraveling a Complex Case with Dr. Alec Yu 28.03.2025 38min

  Dr. Alec Yu is a PGY-4 resident doing his Rheumatology subspecialty training at the University of British Columbia in Vancouver. He has a particular interest in inner city health.
• Episode 48: Almost Live from the ASM - It's Around the Rheum - Day 3 Wrap Up 28.02.2025 21min

  Highlights from Day 3 of the Canadian Rheumatology Associations 2025 Annual Scientific Meeting in Calgary Alberta
• Episode 47: Almost Live from the ASM - It's Around the Rheum - Day 2 Wrap Up 27.02.2025 22min

  Day 2 highlights of the CRA Annual Scientific Meeting in Calgary with Dr. Daniel Ennis, Dr. Janet Pope, Dr. Mo Osman and Dr. Marinka Twilt.
• Episode 46: Almost Live from the ASM - It's Around the Rheum - Day 1 Wrap Up 27.02.2025 24min

  Dr. Mo Osman and Dr. Marinka Twilt join Dan and Janet to break down the highlights of the first day of the CRA ASM in Calgary.
• Épisode 45 : Syndromes auto-inflammatoires avec Docteure Anne-Laure Chetaille 17.01.2025 27min

  Anne-Laure Chetaille est rhumatologue adulte et pédiatrique au CHUL de l'Université Laval à Québec et professeure de clinique agrégée. Ses recherches portent sur les maladies auto-inflammatoires et l'arthrite juvénile idiopathique.
• Episode 44: New Canadian Living Guidelines for Patients with Spondyloarthritis with Dr. Sherry Rohekar 20.12.2024 44min

  Dr. Sherry Rohekar is an associate professor in the division of rheumatology at Western University in London, ON. She has a MSc. in clinical epidemiology and focuses her research on clinical outcomes in patients with spondyloarthritis. She is currently on the executive committee of SPARCC.
• Episode 43: Scleroderma and Chronic Fatigue Syndrome with Dr. Mo Osman 10.10.2024 36min

  Dr. Osman is a clinician scientist who is interested in better understanding the pathogenesis of systemic sclerosis. He also uses point-of-care vascular devices for risk stratifying patients with systemic autoimmune rheumatic diseases (SARDs).
• Episode 42: ANCA Vasculitis with Dr. Arielle Mendel - Part 2 17.09.2024 27min

  Dr. Mendel is a scientist at the Research Institute of the McGill University Health Centre. She is also an Assistant Professor in the Department of Medicine, Faculty of Medicine and Health Sciences, McGill University and a Rheumatologist at the MUHC. Her research focuses on patient safety in systemic autoimmune rheumatic diseases, with an aim to improve medication safety. She was the first author on the CanVasc consensus recommendations for the management of ANCA vasculitis 2020 update.