Eye Research Deep Dive: Doctopus the Octometrist

Episoder

• cosmetics 08.06.2026 19min

  cosmetics
• DRYEYE 2025 Nov: Isotretinoin Effects on Meibomian Glands and Ocular Surface Stability 18.02.2026 15min

  Isotretinoin-induced severe dry eye disease and meibomian gland alterations in patients with acne vulgaris: A noncontact ocular surface analysisJulieana M, Sn-Humaira SMH, Wn-Hasbee WA, Shahidatul-Adha M. Isotretinoin-induced severe dry eye disease and meibomian gland alterations in patients with acne vulgaris: A noncontact ocular surface analysis. Med J Malaysia. 2025 Nov;80(6):780-786. PMID: 41328837.https://pubmed.ncbi.nlm.nih.gov/41328837/
• DRYEYE: Retinoids and Meibomian Glands: A Clinical and Cosmetic Guide 18.02.2026 13min

  1) Oral Isotretinoin Alters Meibomian Gland Function & MorphologyZakrzewska et al. (2023) — Oral isotretinoin therapy led to increased dry eye symptoms and measurable changes in meibomian gland structure and function, including meibography-detectable loss and quality changes.🔗 Free full text: The Effect of Oral Isotretinoin Therapy on Meibomian Gland Characteristics in Acne Patients (Ophthalmology & Therapy)Shows changes in meibomian gland morphology and expressibility with treatment and partial reversibility after cessation.2) Systemic Isotretinoin Impairs Lipid Secretion from Meibomian GlandsZhang et al. (2022) — Oral isotretinoin reduces lipid production from meibomian glands, contributing to evaporative dry eye.🔗 Free full text: Isotretinoin Impairs the Secretory Function of Meibomian Glands (PMC)Systemic isotretinoin induces MGD through reduced lipid synthesis and gland dysfunction.3) Classic Evidence of MG Atrophy with AccutaneMathers et al. (1991) — Meibomian glands show atrophy and reduced function on meibography during Accutane use, with increased tear film osmolarity.🔗 PubMed entry: https://pubmed.ncbi.nlm.nih.gov/1991/07000 … (Note: PubMed entry is shown via summary, full text may require access)4) Pilot Quantitative Meibography StudyGurlevik et al. (2022) — This prospective study measured TFBUT and gland changes before and during isotretinoin treatment.🔗 PubMed entry: https://pubmed.ncbi.nlm.nih.gov/34978652/ … (summary)🧴 Cosmetics & Meibomian Glands5) Eyeliner & Mascara Affect Tear Film Stability + MeibographyErcan et al. (2022) — Eye makeup use (eyeliner, mascara, or both) was associated with significant changes in NBUT and meibography compared with non-users.🔗 Free article: Effect of Eyeliner and Mascara Use on Tear Film and Meibomian Glands (PMC)Does not show changes in aqueous tear production but does show tear instability and gland changes.6) TFOS/Lifestyle Report on Cosmetics & Ocular SurfaceSullivan et al. (2023) — Overview including that eyeliner may induce tear film instability and MGD.🔗 Free article: TFOS Lifestyle: Impact of Cosmetics on the Ocular Surface (PMC)Summarizes research linking eyelid cosmetics (especially eyeliner) to gland dysfunction and tear film instability.
• MYOPIA 2026: Does Past Myopia Progression Predict Future Progression? 16.02.2026 16min

  Does Past Myopia Progression Predict Future Progression?Wesley T. Beaulieu, Michael X. Repka, Stacy L. Pineles, Danielle L. Chandler, Yi Pang, Lori Ann F. Kehler, Catherine O. Jordan, Katherine A. Lee, David B. Petersen, Sarah R. Hatt, Susan A. Cotter, Raymond T. Kraker, Katherine K. Weise, Jonathan M. Holmes, on behalf of the Pediatric Eye Disease Investigator Group; Does Past Myopia Progression Predict Future Progression?. Invest. Ophthalmol. Vis. Sci. 2026;67(1):38. https://doi.org/10.1167/iovs.67.1.38.https://iovs.arvojournals.org/article.aspx?articleid=2811375
• HOYA MiYOSMART iQ Breakthrough Myopia Control Clinical Results 07.02.2026 13min

  HOYA Vision Care recently introduced MiYOSMART iQ, an advanced spectacle lens designed to manage childhood myopia. Interim data from a six-month clinical trial involving children aged 4 to 12 demonstrates that this new technology, featuring Triple Enhanced Design (DIMS TED), significantly outperforms previous models. 
• MYOPIA Apr 2025: Synergistic Efficacy of HALT Lenses and Low-Dose Atropine Therapy 04.02.2026 17min

  Additive Effect of Highly Aspherical Lenslet Target Spectacles to Children Inadequately Controlled by Atropine MonotherapyBryan Xiangrong Sim, Kai Lyn Loh, Hla Myint Htoon, Yudah Sri, Maithily Balakrishnan, Pauline Chan Poh Lin, Ralene Zi Hui Sim, Crystal Shue Wen Lam, Audrey Wei Lin Chia,Additive Effect of Highly Aspherical Lenslet Target Spectacles to Children Inadequately Controlled by Atropine Monotherapy,Ophthalmology Science,Volume 5, Issue 4,2025,100753,ISSN 2666-9145,https://doi.org/10.1016/j.xops.2025.100753.https://www.sciencedirect.com/science/article/pii/S266691452500051X#:~:text=The%20addition%20of%20HALT%20spectacle%20lenses%20significantly%20reduced,supported%20combination%20therapy%20for%20managing%20challenging%20myopia%20cases
• MYOPIA Nov 2025: Myopia Control Efficacy of H.A.L.T. MAX Spectacle Lenses 27.01.2026 18min

  Effect of Increased Power and Asphericity of Highly Aspherical Lenslets on Myopia Control Efficacy: A Contralateral Crossover StudyRajkumar Nallour Raveendran, Wee Sing Ong, Yee Ling Wong, Stella Jinran Zhan, Chun Fan Lee, Si Ying Lim, Björn Drobe; Effect of Increased Power and Asphericity of Highly Aspherical Lenslets on Myopia Control Efficacy: A Contralateral Crossover Study. Trans. Vis. Sci. Tech. 2025;14(11):9. https://doi.org/10.1167/tvst.14.11.9.https://tvst.arvojournals.org/article.aspx?articleid=2811067
• DRYEYE 2024 Jun: Race, Ethnicity, and Risk Perception in Personal Care Product Use 10.01.2026 17min

  Risk perception and use of personal care products by race and ethnicity among a diverse populationMandeville J, Alkhalaf Z, Joannidis C, Ryan M, Nelson D, Quiros-Alcala L, Gribble MO, Pollack AZ. Risk perception and use of personal care products by race and ethnicity among a diverse population. UCL Open Environ. 2024 May 13;6:e3038. doi: 10.14324/111.444/ucloe.3038. Erratum in: UCL Open Environ. 2024 Jun 26;6:e3038.CORR. doi: 10.14324/111.444/ucloe.3038.CORR. PMID: 38757092; PMCID: PMC11098005.https://pmc.ncbi.nlm.nih.gov/articles/pmid/38757092/
• DRYEYE 2023 Jul: The Hidden Impact of Cosmetics on Ocular Surface Health 10.01.2026 14min

  TFOS Lifestyle: Impact of cosmetics on the ocular surfaceSullivan DA, da Costa AX, Del Duca E, Doll T, Grupcheva CN, Lazreg S, Liu SH, McGee SR, Murthy R, Narang P, Ng A, Nistico S, O'Dell L, Roos J, Shen J, Markoulli M. TFOS Lifestyle: Impact of cosmetics on the ocular surface. Ocul Surf. 2023 Jul;29:77-130. doi: 10.1016/j.jtos.2023.04.005. Epub 2023 Apr 13. PMID: 37061220; PMCID: PMC11246752.https://pmc.ncbi.nlm.nih.gov/articles/PMC11246752/pdf/nihms-2004149.pdf
• DRYEYE 2024 May: Beauty versus Health: Eyelash Extensions and Dry Eye Disease 10.01.2026 15min

  Beauty versus Health-How Eyelash Extensions May Affect Dry Eye Disease?Grupcheva CN, Grupchev DI, Usheva N, Grupcheva LO. Beauty versus Health-How Eyelash Extensions May Affect Dry Eye Disease? J Clin Med. 2024 May 25;13(11):3101. doi: 10.3390/jcm13113101. PMID: 38892811; PMCID: PMC11173262.https://pmc.ncbi.nlm.nih.gov/articles/pmid/38892811/
• DRYEYE 2025 Oct: Ocular Adverse Events and Eye Makeup Practices in Jordan 10.01.2026 14min

  Ocular adverse events associated with eye makeup: a cosmetovigilance-based cross-sectional study of prevalence and predictors among Jordanian womenAbusamak M, Al Zoubi S, Alomari AF, Issa SM, Abdul Aziz AA, Musleh A, Alrfooh H, Jarrar YB, Al-Amer R, Hamzeh R, Al-Kuran L, Abusamak TM. Ocular adverse events associated with eye makeup: a cosmetovigilance-based cross-sectional study of prevalence and predictors among Jordanian women. Front Public Health. 2025 Oct 16;13:1681656. doi: 10.3389/fpubh.2025.1681656. PMID: 41179758; PMCID: PMC12571810.https://pmc.ncbi.nlm.nih.gov/articles/pmid/41179758/
• DRYEYE 2023 Apr: The Hidden Toll of Beauty: Ocular Health and Cosmetics 10.01.2026 13min

  TFOS Lifestyle: Impact of cosmetics on the ocular surfaceSullivan DA, da Costa AX, Del Duca E, Doll T, Grupcheva CN, Lazreg S, Liu SH, McGee SR, Murthy R, Narang P, Ng A, Nistico S, O'Dell L, Roos J, Shen J, Markoulli M. TFOS Lifestyle: Impact of cosmetics on the ocular surface. Ocul Surf. 2023 Jul;29:77-130. doi: 10.1016/j.jtos.2023.04.005. Epub 2023 Apr 13. PMID: 37061220; PMCID: PMC11246752.https://pmc.ncbi.nlm.nih.gov/articles/PMC11246752/pdf/nihms-2004149.pdf
• LIDS 2016 APR: Infraorbital Dark Circles: Pathogenesis, Evaluation and Treatment Management 06.01.2026 15min

  Infraorbital Dark Circles: A Review of the Pathogenesis, Evaluation and TreatmentVrcek I, Ozgur O, Nakra T. Infraorbital Dark Circles: A Review of the Pathogenesis, Evaluation and Treatment. J Cutan Aesthet Surg. 2016 Apr-Jun;9(2):65-72. doi: 10.4103/0974-2077.184046. PMID: 27398005; PMCID: PMC4924417.https://pmc.ncbi.nlm.nih.gov/articles/pmid/27398005/
• AMD 2023 Mar: Avacincaptad Pegol for Geographic Atrophy: GATHER1 18-Month Results 19.11.2025 12min

  Avacincaptad pegol for geographic atrophy secondary to age-related macular degeneration: 18-month findings from the GATHER1 trialPatel SS, Lally DR, Hsu J, Wykoff CC, Eichenbaum D, Heier JS, Jaffe GJ, Westby K, Desai D, Zhu L, Khanani AM. Avacincaptad pegol for geographic atrophy secondary to age-related macular degeneration: 18-month findings from the GATHER1 trial. Eye (Lond). 2023 Dec;37(17):3551-3557. doi: 10.1038/s41433-023-02497-w. Epub 2023 Mar 24. Erratum in: Eye (Lond). 2023 Dec;37(17):3705. doi: 10.1038/s41433-023-02548-2. PMID: 36964259; PMCID: PMC10686386.https://pmc.ncbi.nlm.nih.gov/articles/PMC10686386/pdf/41433_2023_Article_2497.pdf
• AMD: Lutein and Zeaxanthin: Roles in Macular Degeneration 18.11.2025 12min

  Lutein and Zeaxanthin: Roles in Macular Degeneration
• AMD 2024 Oct: Upcoming Therapies for Dry and Wet Age-Related Macular Degeneration 18.11.2025 12min

  Dry and neovascular “wet” age‐related macular degeneration: Upcoming therapiesYan A, Hasan N, Chhablani J. Dry and neovascular "wet" age-related macular degeneration: Upcoming therapies. Indian J Ophthalmol. 2025 Jan 1;73(Suppl 1):S55-S65. doi: 10.4103/IJO.IJO_1120_24. Epub 2024 Oct 25. PMID: 39446815; PMCID: PMC11834902.https://pmc.ncbi.nlm.nih.gov/articles/PMC11834902/pdf/IJO-73-55.pdf
• AMD 2022 Jul: AREDS2 Long-Term Outcomes: Lutein, Zeaxanthin, and AMD Progression 18.11.2025 9min

  AREDS2 Long-Term Outcomes: Lutein, Zeaxanthin, and AMD ProgressionChew EY, Clemons TE, Agrón E, Domalpally A, Keenan TDL, Vitale S, Weber C, Smith DC, Christen W; AREDS2 Research Group. Long-term Outcomes of Adding Lutein/Zeaxanthin and ω-3 Fatty Acids to the AREDS Supplements on Age-Related Macular Degeneration Progression: AREDS2 Report 28. JAMA Ophthalmol. 2022 Jul 1;140(7):692-698. doi: 10.1001/jamaophthalmol.2022.1640. PMID: 35653117; PMCID: PMC9164119.https://pmc.ncbi.nlm.nih.gov/articles/pmid/35653117/
• MYOPIA 2024 Dec: DIMS and HAL Spectacles for European Myopia Control 05.11.2025 13min

  Comparison of the performance of myopia control in European children and adolescents with defocus incorporated multiple segments (DIMS) and highly aspherical lenslets (HAL) spectaclesLembo A, Schiavetti I, Serafino M, Caputo R, Nucci P. Comparison of the performance of myopia control in European children and adolescents with defocus incorporated multiple segments (DIMS) and highly aspherical lenslets (HAL) spectacles. BMJ Paediatr Open. 2024 Dec 31;8(1):e003187. doi: 10.1136/bmjpo-2024-003187. PMID: 39741002; PMCID: PMC11749801.https://pmc.ncbi.nlm.nih.gov/articles/pmid/39741002/
• MYOPIA 2021 Sep: Chinese Pediatric Ocular Biometry Percentiles and Myopia Risk 21.10.2025 14min

  Normative data and percentile curves for axial length and axial length/corneal curvature in Chinese children and adolescents aged 4–18 yearsHe X, Sankaridurg P, Naduvilath T, Wang J, Xiong S, Weng R, Du L, Chen J, Zou H, Xu X. Normative data and percentile curves for axial length and axial length/corneal curvature in Chinese children and adolescents aged 4-18 years. Br J Ophthalmol. 2023 Feb;107(2):167-175. doi: 10.1136/bjophthalmol-2021-319431. Epub 2021 Sep 16. PMID: 34531198; PMCID: PMC9887397.https://pmc.ncbi.nlm.nih.gov/articles/PMC9887397/pdf/bjophthalmol-2021-319431.pdf
• MYOPIA 2020 Sep: Accuracy of Pediatric Autorefraction Compared to Cycloplegic Retinoscopy 13.10.2025 13min

  Accuracy of Autorefraction in ChildrenWilson LB, Melia M, Kraker RT, VanderVeen DK, Hutchinson AK, Pineles SL, Galvin JA, Lambert SR. Accuracy of Autorefraction in Children: A Report by the American Academy of Ophthalmology. Ophthalmology. 2020 Sep;127(9):1259-1267. doi: 10.1016/j.ophtha.2020.03.004. Epub 2020 Apr 18. PMID: 32317177.https://www.aaojournal.org/action/showPdf?pii=S0161-6420%2820%2930231-1