Metabolic Mind

Эпизоды

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  BITESIZE: How Chronic Stress Disrupts Metabolic Health 20.08.2026 7мин

  Can chronic stress undermine metabolic health, even when nutrition, sleep, and exercise are in place?In this episode of Metabolic Mind, Dr. Bret Scher explains why stress recovery is an important part of metabolic health and how chronic cortisol and adrenaline activation may affect insulin resistance, blood pressure, inflammation, sleep, and long-term cardiometabolic health.Dr. Scher breaks down the difference between short-term stress that helps us respond to challenges and chronic stress that keeps the body’s alarm system switched on. He also shares why stress recovery doesn’t have to mean an hour of meditation or a weekend nature retreat. Even brief, consistent practices like 10 minutes outside, a short walk, sunlight exposure, calming music, or nature sounds may help the nervous system reset.In the episode, Dr. Scher covers:How chronic stress can affect blood sugar, insulin resistance, and blood pressureWhy cortisol and adrenaline are helpful short term but harmful when constantly elevatedHow stress can disrupt sleep, cognition, inflammation, and metabolic healthWhy meditation works for some people, and why consistency matters more than durationHow nature exposure, sunlight, and natural sounds may support stress recoveryWhy recognizing early stress signals can help prevent bigger health consequencesHow small daily recovery practices can support cardiovascular, metabolic, and brain healthRegular recovery practices give your stress response somewhere to land. A few minutes of meditation, a walk outside, sunlight, music, or even nature sounds can help support steadier blood sugar, better sleep, and a brain and body that aren’t constantly running on high alert.👉 Ready to build your own metabolic mental health plan? Explore THINK+SMART, our free, evidence-informed program designed to help you work with your care team and take practical steps toward supporting metabolic and mental health: metabolicmind.org/thinksmart/🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#MetabolicMind #KetogenicTherapy #NationalWellnessMonthExpert Featured:Bret Scher, MD - Baszucki Group Medical Director & Host of the Metabolic Mind Podcasthttps://www.linkedin.com/in/bret-scher-08baaa102/https://www.instagram.com/drscher858/?hl=enhttps://x.com/bschermdFree CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.
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  Could GLP-1s Help Treat Bulimia and Binge Eating? 18.08.2026 38мин

  Could GLP-1 medications play a role in treating bulimia or binge eating disorder? In this episode of Metabolic Mind, Dr. Bret Scher speaks with Paige Gordon and psychiatrist Dr. Michael Lutter about Paige’s personal experience using a GLP-1 medication for treatment-resistant bulimia, and why researchers are beginning to explore the neurobiology of binge eating.Paige shares how years of therapy and medication never quieted the overwhelming binge urges that drove her bulimia. After hearing someone describe their experience on a podcast, she began exploring GLP-1 medication and saw a profound change in her urges and eating patterns. Dr. Lutter adds the scientific context, including genetic findings that may help explain why some people with binge eating or bulimia respond strongly to GLP-1 medications.They cover:How Paige’s bulimia began and why standard treatments didn’t fully helpWhat “food noise” felt like in her lived experienceWhy GLP-1 medications may affect appetite, reward pathways, and binge urgesHow genetics may help identify who responds to GLP-1sWhy eating disorder treatment needs more precision-focused researchThe risks of using GLP-1 medications in people with restrictive eating disordersWhy stigma keeps many people from discussing this treatment openlyThis conversation explores an emerging area of eating disorder research with hope, caution, and a clear need for larger clinical trials.👉 Want to stay up to date with the latest research on metabolic health and metabolic psychiatry? Sign up for our newsletter to stay informed: metabolicmind.org/about-us/newsletter/🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#MetabolicMind #GLP1 #EatingDisorderTreatmentExpert Featured:Paige Gordonhttps://paigegordonauthor.com/https://www.instagram.com/paigegordonauthor/https://www.linkedin.com/in/paigegordon/https://www.tiktok.com/@paigegordonauthorDr. Michael Lutterhttps://precision-psychiatry.com/https://www.linkedin.com/in/michaelluttermd/https://www.youtube.com/@precisionpsychiatryFree CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.
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  First Keto RCT for Serious Mental Illness: Hear from the Study Authors 16.08.2026 28мин

  Can ketogenic therapy improve symptoms, cognition, and metabolic health in people living with serious mental illness?In this episode of Metabolic Mind, Dr. Bret Scher speaks with Dr. Judy Ford, Juliette Kyner (previously Juliette Ward), and Dr. Shebani Sethi about the first-ever randomized controlled trial of a ketogenic diet intervention in individuals living with schizophrenia spectrum disorder or bipolar I disorder with psychotic features.The conversation explores what made this trial possible, from prepared meals and coaching to the structured support that helped participants stay engaged. It also highlights encouraging four-month findings across metabolic health, cognition, depressive symptoms, and both positive and negative psychiatric symptoms.They discuss:Why this trial is an important step for metabolic psychiatryHow participants adhered to a ketogenic diet with structured supportWhat changed in metabolic health markers like BMI, A1C, and HOMA-IRWhy cognitive improvements were especially meaningfulHow positive symptoms, negative symptoms, and depressive symptoms changed over timeWhat family members noticed as participants re-engaged with daily lifeWhy future studies may need to be longer, larger, and more mechanisticThis trial marks an important step for metabolic psychiatry and points to the need for larger, longer, fully controlled studies that can better clarify how ketogenic interventions may affect metabolic, cognitive, and psychiatric outcomes.👉 Learn more about this trial on our study page: First-Ever Randomized Controlled Trial of Ketogenic Diet in Schizophrenia-Spectrum and Bipolar I Disorder🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#MetabolicMind #KetogenicTherapy #Schizophrenia #BipolarDisorderExpert Featured:Dr. Judy Fordhttps://bbrfoundation.org/about/people/judith-m-ford-phdJuliette Kyner, Research Assistant at UCSFhttps://www.linkedin.com/in/juliette-marie-kyner/Dr. Shebani Sethihttps://www.metabolicpsychiatry.com/teamhttps://www.linkedin.com/in/drsethi/https://x.com/ShebaniMDResources Mentioned:Metabolic Improvements with a Ketogenic Diet Correlate with Symptom Improvement in Psychosis: A Randomized Controlled Trialhttps://doi.org/10.1093/schbul/sbag082Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.
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  BITESIZE: New GLP-1 Study Raises Metabolic Health Questions 13.08.2026 5мин

  Do GLP-1 medications improve metabolic health as much as they support weight loss? A new observational study in the Annals of Internal Medicine raises an important question about semaglutide, insulin discontinuation, type 2 diabetes, and what meaningful metabolic improvement may require.In this episode of Metabolic Mind, Dr. Bret Scher breaks down a real-world study of more than 9,000 veterans with type 2 diabetes who were using insulin and then added either a GLP-1 receptor agonist, SGLT2 inhibitor, or DPP4 inhibitor. Despite semaglutide’s stronger association with weight loss, the study found similar insulin discontinuation rates across all three groups over three years.Dr. Scher covers:Why weight loss and metabolic health improvements may not always move togetherWhat insulin discontinuation can reveal about insulin resistance and beta cell functionWhy semaglutide did not outperform older diabetes medications in this studyThe limitations of observational research and real-world medication dataHow GLP-1 medications and therapeutic carbohydrate reduction may work through complementary mechanismsWhy combining GLP-1s with therapeutic carbohydrate reduction may be an important area for future research and clinical practiceThis conversation takes a closer look at what metabolic health means, and why the path from weight loss to insulin independence may be more complex than the scale alone can show.👉 Want to stay up to date with the latest research on metabolic health and metabolic psychiatry? Sign up for our newsletter to stay informed: metabolicmind.org/about-us/newsletter/🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#MetabolicMind #KetogenicTherapy #GLP1Expert Featured:Bret Scher, MD - Baszucki Group Medical Director & Host of the Metabolic Mind Podcasthttps://www.linkedin.com/in/bret-scher-08baaa102/https://www.instagram.com/drscher858/?hl=enhttps://x.com/bschermdResources Mentioned:Comparative Effectiveness of Glucagon-like Peptide-1 Receptor Agonists Versus Oral Agents for Insulin Discontinuation in Type 2 Diabetes : A Target Trial Emulationhttps://www.acpjournals.org/doi/10.7326/ANNALS-25-05216Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.
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  Q&A: Insulin Resistance, Reaching Ketosis, Bone Density, and Rating Popular Keto Products 11.08.2026 23мин

  The questions around ketogenic therapy keep getting more layered, and your latest submissions reflect that. In this Metabolic Mailbag episode, Dr. Bret Scher and producer Erica Gerard tackle some of the most common questions about insulin resistance, ketosis, bone health, and a fun rapid-fire round on popular ketogenic products and practices.In this discussion, you'll learn:The difference between pathologic and physiologic insulin resistance and why insulin levels matter mostWhy someone in deep ketosis may fail a glucose tolerance test and how to interpret itHow metabolic health affects how strict your ketogenic approach needs to beWhy some people can stay in ketosis at 75 grams of carbs while others need under 25Why claims about ketogenic diets causing bone loss don't hold up under scrutinyThe role of protein intake, resistance training, and walking in supporting bone densityA rapid-fire round covering MCT oil, electrolytes, caffeine, diet sodas, keto bread, creatine, exogenous ketones, intermittent fasting, and artificial sweetenersThis conversation captures the nuance that ketogenic therapy and metabolic health really call for, while keeping the practical realities of everyday life in view.🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#KetogenicTherapy #MetabolicMind #MetabolicPsychiatryExpert Featured:Dr. Bret ScherBaszucki Group Medical Directorhttps://x.com/bschermdResources Mentionedhttps://www.youtube.com/watch?v=3m6Fm0nXaMQ&t=2sFree CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.
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  Robyn Dobbins Reflects on Her Story in The Cholesterol Code 09.08.2026 8мин

  What does it look like to put bipolar II disorder into remission and become a voice of hope for others living with serious mental illness? Robyn Dobbins joins Hannah Warren from Metabolic Mind to reflect on how ketogenic therapy transformed her life, and what it was like to see her own story featured in The Cholesterol Code documentary.In this conversation, you'll learn:What it was like for Robyn to see her personal story on the big screenWhy she has always been open about her mental health journey, even at the time of her bipolar II diagnosisHow her psychiatric symptoms showed up before ketogenic therapy, including persistent anger, exhaustion, and the urge to escape her own lifeWhat changed once she began ketogenic therapy and how her day-to-day experience shiftedWhy she continues to advocate for awareness around metabolic therapies for mental illnessHow The Cholesterol Code documentary could expand awareness of ketogenic therapy beyond current circlesWhat inspires Robyn to keep sharing her story and how she hopes it reaches others still sufferingRobyn's openness about her journey is helping break the stigma around serious mental illness and expand awareness of what recovery can look like.🎥 Watch The Cholesterol Code documentary and join the conversation shaping the future of metabolic health: https://www.youtube.com/watch?v=57Z8bUb1P94🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#MetabolicPsychiatry #KetogenicTherapy #MetabolicMind #BipolarDisorderExpert By Experience Featured:Robyn Dobbinshttps://x.com/robynrdobbinshttps://www.facebook.com/people/Robyn-R-Dobbins/100090891465253/https://www.linkedin.com/in/robyn-dobbins-59bb1653/https://www.instagram.com/robynrdobbins/Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.*Disclaimer: Tapering psychiatric medication isn’t the goal for everyone, and adjusting doses too quickly can be dangerous. Medications should never be stopped abruptly, and changes should always be made with your prescriber.Visit Inner Compass Initiative [https://www.theinnercompass.org/] for more information on safe tapering.
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  BITESIZE: Keto 101: Everything You Need to Know About Ketone Testing 06.08.2026 5мин

  How do you know if you're actually in ketosis? Should you test ketones? And if so, what's the best method: blood, breath, or urine?Dr. Bret Scher breaks down everything you need to know about ketone testing, including when testing matters, which tools are most accurate, and how to interpret your results based on your goals. Whether you're using a ketogenic diet for metabolic health, weight loss, or therapeutic ketosis for mental health and neurological conditions, understanding ketone testing can help you personalize your approach.In this video, you'll learn:Why ketone testing can be a valuable toolWhen ketone levels matter, and when they may notThe differences between urine strips, breath meters, and blood ketone monitorsPros and cons of each testing methodHow often to test and the best times of day to measure ketonesWhy ketone levels naturally fluctuate throughout the dayThe emerging role of continuous ketone monitors (CKMs)How to use ketone data without becoming overwhelmed or obsessiveUltimately, there isn't one "perfect" ketone number for everyone. The value of ketone testing depends on your goals, your health condition, and how you respond to ketosis. The most useful data is the data that helps you make informed decisions and better understand your own metabolism.🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#MetabolicMind #KetogenicTherapy #KetoneTestingExpert Featured:Dr. Bret ScherBaszucki Group Medical Directorhttps://x.com/bschermdFree CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits:https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.
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  Targeting Cancer Metabolism With Ketogenic Therapy and Fasting 04.08.2026 36мин

  Could metabolic therapies become part of the future of cancer care?That question sits at the center of Dr. Bret Scher’s conversation with neurologist and researcher Dr. Matthew Phillips, whose recent study explored a metabolic approach in people with glioblastoma, one of the most aggressive forms of brain cancer.Rather than relying on a single intervention, the study combined a ketogenic diet, intermittent fasting, and repeated five-day fasts alongside standard chemotherapy and radiation. Together, these strategies were designed to lower the Glucose Ketone Index, or GKI, by reducing glucose and increasing ketones.In this conversation, they explore:Why cancer cell metabolism is becoming an important area of researchHow glucose, ketones, and mitochondrial function may influence cancer growthWhy the GKI was a central target in the studyHow fasting and ketogenic therapy were integrated with standard cancer treatmentThe difference between intentional weight loss and cancer cachexiaWhy quality of life deserves as much attention as survivalWhat the study’s long-term survivors may teach researchersWhy larger randomized trials are still neededParticipants following the metabolic protocol achieved an average GKI of 1.88, and every participant completed all eight five-day fasts. The metabolic therapy group also had a median survival of 21 months compared with 14 months in the control group, along with a higher rate of survival beyond three years.These results offer a compelling reason to keep studying this approach, particularly in a cancer with such limited treatment options and a difficult prognosis. Since the trial was small and nonrandomized, it can’t provide definitive answers, but it does give researchers a strong foundation to build on.👉 Want to stay up to date with the latest research on metabolic health and metabolic psychiatry? Sign up for our newsletter to stay informed: metabolicmind.org/about-us/newsletter/🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#MetabolicMind #KetogenicTherapy #FoodAsMedicineExpert Featured:Dr. Matthew Phillipshttps://www.metabolicneurologist.com/https://x.com/drmclphillipsResources Mentioned:Intensive multimodal ketogenic metabolic therapy in glioblastoma: A clinical trialhttps://doi.org/10.1093/noajnl/vdag165Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.
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  BITESIZE: JAMA Psychiatry Analysis: What 50 Studies Tell Us About Nutrition For Depression & Anxiety 02.08.2026 6мин

  Can a ketogenic diet help improve mood and reduce depressive symptoms?A new meta-analysis published in JAMA Psychiatry examined 50 different keto studies, totaling over 40,000 participants, that included depression and anxiety outcomes. The results of the review demonstrated a modest improvement in depression symptoms across different populations and diagnoses in both controlled and real-world scenarios, and greater symptom improvement was observed in trials that included ketone monitoring. Improvements in anxiety were also observed in most studies, but with less consistency than depressive symptoms.While many of these studies weren't originally designed to treat depression or anxiety, the consistent improvements associated with verified ketosis as well as the larger effect seen in “very low carbohydrate” diets compared to just “low carbohydrate” diets, tell us that ketogenic therapy for depression warrants further investigation. And when we combine the findings with the results of another recent additional study on keto for depression (not included in the analysis), we can’t help but wonder how many people could benefit from ketogenic therapy.In this video, Dr. Bret Scher breaks down:What the JAMA Psychiatry paper actually reviewedHow ketosis may support mood and brain functionKey findings from both randomized and non-randomized trialsHow measuring ketosis was associated with better depression improvementsSafety considerations and medication interactions to watch forThis JAMA review highlights growing scientific interest in ketogenic therapy for serious mental illness, driven by early scientific evidence and thousands of individuals worldwide reporting significant improvements in mental health with ketogenic therapy.Looking for more information on ketogenic therapy for depression? Sign up for our newsletter to be the first to be notified when our brand-new Keto for Depression Resource Hub is available!https://www.metabolicmind.org/about-us/newsletter/Expert Featured:Dr. Bret ScherMedical Director, Metabolic Mind and Baszucki Grouphttps://x.com/bschermdResources Mentioned:Ketogenic Diets and Depression and Anxiety: A Systematic Review and Meta-Analysishttps://doi.org/10.1001/jamapsychiatry.2025.3261Blog: A Ketogenic Diet was Associated with improvements in Depression in College Studentshttps://www.metabolicmind.org/resources/news-views/blog/perspectives-in-metabolic-psychiatry/new-research-a-ketogenic-diet-improved-depression-in-college-students/Edinburgh Trial Showing Improvements in Depression Symptoms in Patients Living with Bipolar Disorderhttps://www.metabolicmind.org/trials/featured-post/first-european-trial-shows-promise-of-keto-as-a-new-treatment-for-bipolar/Stanford Study Shows Keto Improves Symptoms of Serious Mental Illnesshttps://www.metabolicmind.org/trials/featured/stanford-study-shows-promise-of-keto/Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.
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  BITESIZE: New Study: Could GLP-1 Medications Be Reducing Physical Activity? 30.07.2026 7мин

  Do GLP-1 medications like Ozempic reduce physical activity? Preliminary research suggests they might, raising important questions about how exercise should be supported alongside treatment.GLP-1 medications are helping many people achieve meaningful weight loss and metabolic improvements. At the same time, findings presented at the Endocrine Society’s annual meeting showed declines in daily steps and moderate-to-vigorous activity after treatment began. In this video, Dr. Bret Scher examines those results, explores why activity levels may fall, and explains how similar concerns can arise with medications such as statins and antipsychotics.He covers:What the study found about physical activityWhy side effects and rapid weight loss may reduce movementHow muscle loss can affect long-term metabolic healthWhy resistance training and protein intake matterHow clinicians can provide more structured exercise supportThese findings highlight the importance of pairing GLP-1 medications with proactive support for physical activity and muscle preservation. More broadly, they suggest that when a treatment can affect appetite, energy, or body composition, those effects should be monitored and addressed as part of ongoing care.👉 Want to stay up to date with the latest research on metabolic health and metabolic psychiatry? Sign up for our newsletter to stay informed: metabolicmind.org/about-us/newsletter/🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#MetabolicMind #KetogenicTherapy #GLP1Expert Featured:Bret Scher, MD - Baszucki Group Medical Director & Host of the Metabolic Mind Podcasthttps://www.linkedin.com/in/bret-scher-08baaa102/https://www.instagram.com/drscher858/?hl=enhttps://x.com/bschermdFree CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.
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  GLP-1s + Ketogenic Diet: The Future of Weight Loss? 28.07.2026 28мин

  Could a ketogenic diet and low-dose GLP-1 medications work better together? A new case series suggests they might, while highlighting a more personalized approach to metabolic health.GLP-1 medications have transformed obesity treatment, but they aren't the only tool available. In this interview, Dr. Bret Scher speaks with physician assistant Bill Jensen about a newly published case series exploring the combination of a ketogenic diet and low-dose semaglutide. Together, they discuss how this approach may help preserve lean mass, improve insulin resistance, reduce side effects, and empower patients to take an active role in their health.In this video:Why low-dose GLP-1s may complement a ketogenic dietThe importance of preserving muscle during weight lossWhich patients may benefit most from this approachWhy this case series is hypothesis-generating, not definitiveHow lifestyle and medication can work together to improve metabolic healthThis conversation examines how a more personalized approach to care could improve long-term health outcomes. Rather than asking whether medication or lifestyle is "better," it explores how combining the right tools for the right person may help improve body composition, support metabolic health, and empower patients to play an active role in their care.💡 Not all ketogenic diets are the same. If you’re interested in learning more about what a well-formulated ketogenic diet looks like, check out our blog: Understanding the Well-Formulated Ketogenic Diet.🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#MetabolicMind #KetogenicTherapy #GLP1Expert Featured:Bill Jenson PA-C, MMShttps://www.summitfamilyhealth.org/dr-jensenhttps://www.linkedin.com/in/william-jensen-45027053/https://www.instagram.com/summitmetabolichealth/Resources Mentioned:Personalized Combination of a Ketogenic Diet and Low-Dose Semaglutide for Cardiometabolic Health: A Retrospective Case Serieshttps://doi.org/10.3390/jpm16060313Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.
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  Dr. Ford Brewer on the Future of Heart Health & The Cholesterol Code 26.07.2026 20мин

  What does it take to truly understand and assess cardiovascular risk in modern medicine?Dr. Bret Scher joins Dr. Ford Brewer at the Collaborative Science (CoSci) conference to discuss the recent screening of The Cholesterol Code documentary and the bigger picture of metabolic health, cardiac imaging, and the future of risk assessment.In this conversation, you'll learn:Dr. Ford Brewer's reaction to The Cholesterol Code documentary and what stood out mostWhy metabolism, not just plumbing, drives cardiovascular diseaseHow CT angiogram with AI analysis is becoming the gold standard in cardiac imagingWhat CIMT (Carotid Intima-Media Thickness) measures and where it fits in evaluating riskWhy calcium scores can miss important soft plaqueWhat to look for when seeking a high-quality CIMT scanDr. Brewer's personal story of being diagnosed with manic depression in medical school and how lifestyle and metabolic changes shaped his journeyWhy GLP-1 medications, when used responsibly, can be a useful tool rather than a stand-alone solutionHow the overuse of statins and GLP-1s reflects broader issues in modern medicineThis discussion captures the value of bringing nuanced, individualized thinking into the conversation around cardiovascular risk, metabolic health, and mental wellness.🔎 Learn more about CIMT tests on our blog: Early Heart Disease Detection? Why You May Consider a CIMT Test🎥 Watch The Cholesterol Code documentary and join the conversation shaping the future of metabolic health: https://www.youtube.com/watch?v=57Z8bUb1P94#MetabolicMind #KetogenicTherapy #HeartDiseaseExpert Featured:Dr. Ford Brewerhttps://prevmedhealth.com/https://www.youtube.com/channel/UCmoEsq6a6ePXxgZeA4CVrUwhttps://www.instagram.com/brewer.fordhttps://www.linkedin.com/in/fordbrewer/https://www.facebook.com/DrFordBrewer/Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.
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  BITESIZE: We Can Reverse T2 Diabetes. That Doesn’t Mean Patients Are at Fault 23.07.2026 6мин

  Type 2 diabetes is a chronic disease that can often be put into remission. So why do so many people still struggle to get better?In this discussion, Dr. Bret Scher explores how the environments we create, from our food system to our healthcare system, shape metabolic health in ways that are often overlooked.Using a thought experiment as a starting point, he examines why remission is possible for many people with type 2 diabetes, why that shouldn't be confused with 100% personal responsibility, and what needs to change if we want to improve outcomes at scale.He covers:Why type 2 diabetes remission is possible for many peopleHow ketogenic nutrition and other metabolic therapies can improve insulin resistanceWhy type 1 and type 2 diabetes require fundamentally different approachesHow modern food environments contribute to metabolic dysfunctionThe limitations of decades of conventional nutrition adviceWhy clinician education and public policy matter for metabolic healthHow shifting the conversation from blame to biology can improve patient careGrowing evidence continues to show that metabolic health can be improved through nutrition and lifestyle interventions when people have the right support. Building healthcare systems and food environments that reflect that science could help more people achieve better long-term health.👉 Want to stay up to date with the latest research on metabolic health and metabolic psychiatry? Sign up for our newsletter to stay informed: metabolicmind.org/about-us/newsletter/🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#MetabolicMind #Diabetes #KetogenicTherapyExpert Featured:Dr. Bret ScherBaszucki Group Medical Directorhttps://x.com/bschermdFree CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits:https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.
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  Meet Dr. Bret Scher: The Host Behind Metabolic Mind 21.07.2026 47мин

  Dr. Bret Scher began his career practicing conventional cardiology, following the same guidelines taught in medical training. Today, he is Medical Director at Metabolic Mind, as well as The Coalition for Metabolic Health, and one of the leading voices advancing metabolic health, ketogenic therapy, and metabolic psychiatry.What changed?In this special episode, Metabolic Mind producer Erica Gerard turns the tables and interviews Dr. Scher about the experiences, patients, and pivotal moments that challenged his thinking and reshaped his approach to medicine.In this conversation, you'll learn:How a conventionally trained cardiologist became known as the "low-carb cardiologist"The patients who changed the way he thought about nutrition and metabolic healthWhy he believes medicine should treat individuals, not just follow guidelinesWhat drew him from cardiovascular medicine into the emerging field of metabolic psychiatryHow interviewing researchers, clinicians, and patients has influenced his perspective on evidence and clinical careHis hopes for the future of metabolic health and what it could mean for medicineAlong the way, Dr. Scher shares personal stories from his childhood, medical training, career, and family life, offering a rare look at his curiosity, humility, and willingness to challenge his own assumptions that continue to shape his work today.Whether you've followed Dr. Scher's work for years or meeting him for the first time, this conversation offers insight into the journey behind one of the most trusted voices in metabolic medicine.👉 Learn more about Metabolic Mind, Dr. Scher, and the metabolic psychiatry movement at metabolicmind.org🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#MetabolicMind #KetogenicTherapy #MetabolicPsychiatryExpert Featured:Erica Gerard - Metabolic Mind ProducerBret Scher, MD - Medical Director & Host of the Metabolic Mind Podcasthttps://www.linkedin.com/in/bret-scher-08baaa102/https://www.instagram.com/drscher858/?hl=enhttps://x.com/bschermdExpert Mentioned:Dr. Georgia Ede, MD- Author, Change Your Diet, Change Your Mindhttps://www.linkedin.com/in/georgiaedemd/https://x.com/GeorgiaEdeMDhttps://www.instagram.com/georgiaedemd/Dr. Andreas Eenfeldthttps://www.youtube.com/user/eenfeldt/videoshttps://se.linkedin.com/in/dietdoctorJan Ellison Baszuckihttps://www.metabolicmind.org/team/jan-ellison-baszucki/https://www.linkedin.com/in/janellisonbaszuckihttps://www.instagram.com/jan_ellison_baszucki/?hl=enFree CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.
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  Psychiatry Research Priorities: Keto, GLP-1s, Exercise & Mental Illness 19.07.2026 29мин

  What questions matter most to people living with serious mental illness when it comes to metabolic interventions?Dr. Dina Farran and Dr. Toby Pillinger from King's College London set out to answer exactly that through a Priority Setting Partnership, an extensive collaborative process bringing together people with lived experience, family members, caregivers, clinicians, and researchers to identify the top research priorities in metabolic psychiatry.Their findings reveal a powerful shift in how patients and clinicians think about mental illness, and what the future of treatment may look like.In this conversation, you'll learn:What a Priority Setting Partnership is and why it matters for psychiatric researchHow over 450 participants and 1,400 submissions were narrowed down to a top 10 listWhy 8 of the top 10 priorities focused on mental health outcomes, not just physical healthWhy ketogenic diets ranked as the number one research priorityHow GLP-1 medications, exercise, gut health, and nutrient deficiencies entered the conversationWhy patients and caregivers may have a more integrated view of mental illness than the research fieldWhat this roadmap means for the future of metabolic psychiatry research and careThis interview captures a meaningful turning point in how the field of metabolic psychiatry is beginning to align with what truly matters to the people it serves.Interested in learning more about metabolic psychiatry? Check out our blog: What is Metabolic Psychiatry?🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#MetabolicMind #MetabolicPsychiatry #KetogenicTherapyExpert Featured:Dr. Dina Farranhttps://uk.linkedin.com/in/dina-farran-225028288Dr. Toby Pillingerhttps://www.kcl.ac.uk/people/toby-pillingerhttp://uk.linkedin.com/in/toby-pillingerResources Mentioned:PSP has been previously run by: https://www.jla.nihr.ac.uk/https://www.nih.gov/Where the manuscript will be published: https://www.thelancet.com/journals/lanpsy/homeExperts mentioned:Danny Smithhttps://edwebprofiles.ed.ac.uk/profile/professor-daniel-j-smithFree CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits:https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.
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  BITESIZE: Lipidologist Questions the New Keto and Liver Disease Study 16.07.2026 8мин

  A recent study made headlines for claiming a ketogenic diet may worsen fatty liver disease and raise triglycerides. But when you take a closer look at the research, it’s clear that the conclusions are far less supported than the coverage suggests.To clear things up, Dr. Bret Scher breaks down what the study actually found, where the methodology falls short, and what the broader body of research has to say about ketogenic therapy and liver health.In this discussion, you'll learn:What the study examined and how the data was collectedWhy the lack of ketone measurement makes it impossible to confirm anyone was actually in ketosisHow reverse causality may explain the findings entirelyWhat baseline differences in BMI and adiposity reveal about the study populationWhy cross-sectional observational studies sit lower on the evidence hierarchy than RCTsWhat a meta-analysis of 62 randomized controlled trials shows about ketogenic diets and triglyceridesWhat a 12-week supervised intervention revealed about ketogenic therapy and fatty liver reductionWhy higher-quality controlled trial evidence should take precedence over headline-grabbing observational studiesFor clinicians, researchers, and anyone navigating conflicting headlines about ketogenic therapy, this conversation is a reminder that the quality of evidence matters as much as the findings themselves.🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#KetogenicTherapy #MetabolicMind #FattyLiverDiseaseExpert Featured:Dr. Bret ScherBaszucki Group Medical Directorhttps://x.com/bschermdResources Mentioned:Association between dietary patterns and lipid profile in patients with non-alcoholic fatty liver disease: a retrospective cross-sectional studyhttps://doi.org/10.3389/fnut.2026.1794910Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.
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  How One CGM Changed This Cardiologist’s Life 14.07.2026 42мин

  Is a plant-based diet the best for supporting metabolic health? Cardiologist Dr. Jaimela Dulaney spent years practicing plant-based nutrition before her own experience with insulin resistance, blood sugar swings, and endurance running led her to rethink what personalized nutrition can look like.In this episode, Dr. Bret Scher speaks with Dr. Dulaney about what changed her perspective, both personally and professionally.They cover:How CGMs helped reveal unexpected blood sugar patternsWhy insulin resistance can show up even in active, normal-weight individualsHow Dr. Dulaney thinks about LDL cholesterol in the context of metabolic healthWhy low-carb and ketogenic diets may help some people improve energy, recovery, and blood sugar stabilityWhy there may not be one “best diet” for every patientThis conversation highlights the importance of listening to patients, tracking meaningful lab trends, and staying open to new evidence when personal experience and clinical outcomes begin to tell a different story.👉 Interested in learning more about metabolic health, cholesterol, and heart disease? Check out our article: Beyond LDL: New Insights into Metabolic Health and Heart Disease.🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.#MetabolicMind #KetogenicTherapy #HeartDiseaseExpert Featured:Dr. Jaimela Dulaneyhttps://doctordulaney.com/https://www.youtube.com/@jjd862Expert Mentioned:Andrew Koutnikhttps://www.instagram.com/andrewkoutnikphd/https://www.youtube.com/channel/UCuBoAR4gzVC5Y0e5raQLPkQhttps://www.linkedin.com/in/andrewkoutnikphd111/Dr. Noakeshttps://register.cpso.on.ca/physician-info/?cpsonum=50902https://surgery.utoronto.ca/faculty/jeffrey-noakesResources Mentioned:Additional resourcesDr. Noakes book: Lore of Nutrition: Challenging Conventional Dietary BeliefsDr. Esselstyn - https://www.dresselstyn.com/site/Dean Ornish: Ornish program — http://ornish.com/Nina Teicholz Book: The Big Fat SurpriseFree CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.
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  Dr. Dom D'Agostino on Why Metabolic Health Matters for the Brain 12.07.2026 13мин

  Metabolic health may be the foundation of a healthy brain, and a growing community of researchers, clinicians, and educators is working to bring that message into mainstream medicine.In this interview, Dr. Bret Scher talks with Dr. Dom D'Agostino at the Citizen Science Initiative (CoSci) conference to discuss everything from the recent screening of The Cholesterol Code documentary to the rise of N-of-1 research, the future of metabolic psychiatry, and the urgent need for nutrition education in medical schools.In this conversation, you'll learn:Dr. D'Agostino’s reaction to The Cholesterol Code documentary and what stood out mostHow N-of-1 citizen science is reshaping the way we think about metabolic healthWhy metabolic health may be a stronger predictor of cardiovascular outcomes than LDL aloneHow nutrition education made its way into the USF College of Medicine curriculumWhat the latest research is revealing about ketogenic metabolic therapy and cancer, brain health, and immune functionWhy metabolic psychiatry is one of the most exciting emerging fields in medicineHow exogenous ketones and ketogenic diets fit into clinical practice and ongoing researchThis discussion offers a thoughtful look at where metabolic medicine is headed and why prioritizing whole-body health is becoming central to supporting the brain.🎥 Watch The Cholesterol Code documentary and join the conversation shaping the future of metabolic health: amazon.com/gp/video/detail/B0GS8ZFCYN/ref=atv_dp_share_cu_r#MetabolicMind #KetogenicTherapy #FoodAsMedicine🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.Expert Featured:Dr. Dominic D’Agostinohttps://drdominicdagostino.com/https://www.instagram.com/dominic.dagostino.kt/?hl=enhttps://www.facebook.com/dominic.dagostino.1/http://linkedin.com/in/dominic-d-agostino-156014bhttps://x.com/DominicDAgosti2?lang=enResources Mentioned:https://www.metabolicinitiative.com/https://www.youtube.com/playlist?list=PL27U85_g28NlX2RAWCiz6us2SW_9OW4VAFree CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.
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  First RCT of Keto for Schizophrenia & Bipolar Disorder: Results & Future Directions 10.07.2026 21мин

  New results from first-of-its-kind randomized controlled trial on a ketogenic diet for schizophrenia and bipolar disorder with psychosis offer important insights into metabolic psychiatry and mental health treatment.In this interview, Dr. Bret Scher sits down with Dr. Julie Milder to walk through the study results, recently published in Schizophrenia Bulletin. As the first RCT in psychosis-spectrum conditions to publish in the peer-reviewed literature, it’s an important step toward understanding how metabolic interventions may play a role in serious mental illness.Key insights from the study:In the 1-month randomized portion of the trial, the ketogenic group showed significant improvements in metabolic health markers compared to diet-as-usualPsychiatric symptoms trended toward improvement, but were not statistically significant at 1 monthParticipants who opted into the ketogenic extension part of the study (4 total months of keto), saw improvements in depression, cognition, and positive and negative symptoms.In this video, Dr. Milder also breaks down important additional context about the limitations of the study, including the length of the randomized portion of the trial and the variance in dietary support between the two diet groups.This study adds to growing evidence linking metabolic health and psychiatric conditions and explores whether ketogenic therapy may play a role in addressing underlying mechanisms.👉 Want to learn more about the trial? Visit our study page: https://www.metabolicmind.org/trials/featured-post/peer-reviewed-results-of-first-ever-randomized-controlled-trial-of-ketogenic-diet-in-schizophrenia-spectrum-and-bipolar-i-disorder/🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.Expert Featured:Dr. Julie MilderBaszucki Group Director of Neurosciencehttp://linkedin.com/in/juliemilderDr. Bret ScherBaszucki Group Medical Directorhttps://x.com/bschermdResources Mentioned:Metabolic improvements with a ketogenic diet correlate with symptom improvement in psychosis: A randomized controlled trialhttps://doi.org/10.1093/schbul/sbag082Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits:https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.
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  BITESIZE: Results from first RCT of Keto for Schizophrenia + Bipolar: Metabolic Wins & Mental Health Signals 08.07.2026 4мин

  New evidence from the first-ever RCT shows ketogenic therapy can rapidly improve metabolic health in schizophrenia-spectrum and bipolar I disorders, and shows early signals of psychiatric improvement.In this video, Dr. Bret Scher breaks down this newly published study led by Dr. Judith Ford at UCSF: the first randomized controlled trial with peer-reviewed results investigating ketogenic therapy in people with schizophrenia-spectrum disorders and bipolar-1 disorder with psychotic features.You’ll learn:How the study was designed (a 1-month randomized phase plus an optional 3-4 month single-arm extension)What happened in the first 30 days (clear improvements in metabolic markers; psychiatric outcomes showed trends that did not reach statistical significance in the randomized portion)What improved over longer follow-up in the extension phase (encouraging changes in metabolic health, cognition, and psychiatric measures)Why this matters for patients and families today, and what future, longer controlled trials need to confirmPublished in Schizophrenia Bulletin and funded by the NIMH and Baszucki Group, this study adds to the growing literature on the potential benefit of ketogenic therapy for psychiatric disorders.These results indicate the need for larger, extended randomized controlled trials to test the safety and efficacy of ketogenic therapy in patients living with serious mental illness.👉 Learn more about the study by visiting our website: https://www.metabolicmind.org/trials/featured-post/peer-reviewed-results-of-first-ever-randomized-controlled-trial-of-ketogenic-diet-in-schizophrenia-spectrum-and-bipolar-i-disorder/🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.Expert Featured:Dr. Bret Scher, MD, FACCBaszucki Group Medical Directorhttps://x.com/bschermdResources Mentioned:Metabolic improvements with a ketogenic diet correlate with symptom improvement in psychosis: A randomized controlled trialhttps://doi.org/10.1093/schbul/sbag082Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits:https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.