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  #155 - Meet The World’s Greatest Endogenous DMT Psychedelic Scientist You've Never Heard Of 14.09.2026 1ч 26мин

  🧠 JOIN THE GIANT'S SHOULDER FAMILYBecome a YouTube Member for exclusive episodes, early access + ad-free viewing 👇 https://www.youtube.com/@thegiantsshoulder/joinSteven Barker is the chemist who has spent fifty years proving your brain makes its own psychedelic. He built the mass-spectrometry methods sensitive enough to find DMT in living tissue, and showed it sits in the brain at concentrations rivalling serotonin and dopamine. In 1981 the war on drugs cut his funding and the work stopped for fifteen years. He also synthesised his own supply — and took it.Expect to learn:- The locked cabinet: what his mentor kept behind two locks, and why Barker raided it- The missing neurotransmitter: why DMT meets every formal criterion and nobody noticed- Machine elves: why he calls the term marketing rather than science- DMT immunity: the lab technician who took a full dose and felt nothing- Receptors inside the neuron: the 2023 finding that explains the neuroplasticitySPONSORSDownload the most scientifically rigorous nutrition app MacroFactor! Use code GIANTS for a 2 week FREE trial - https://app.macrofactor.com/mfgiantsGS EPISODES MENTIONEDAndrew Gallimore - No.1 DMT Neurobiologist: Alien Worlds, DMT Entity Encounters, Attractor States and Consciousness: https://youtu.be/USgWrxEFWDARick Strassman - Meet The Father Of Modern DMT Research: https://youtu.be/KeAZOj7tYscDennis McKenna - Dennis McKenna: "I've Spent 50 Years Investigating The Entities That Exist Within Ayahuasca": https://youtu.be/gTSBhfZhuD8David Nichols - Meet The Greatest Living Psychedelic Scientist You've Never Heard Of: https://youtu.be/6umTgXsW1lQGUEST LINKSResearchGate Profile: https://www.researchgate.net/scientific-contributions/Steven-A-Barker-2164230436N,N-Dimethyltryptamine, an Endogenous Hallucinogen (2018 review): https://doi.org/10.3389/fnins.2018.00536A Critical Review of Endogenous DMT in Humans 1955-2010 (with Strassman): https://doi.org/10.1002/dta.422LC/MS/MS Analysis of Rat Pineal Microdialysate (2013, the paper discussed on tape): https://doi.org/10.1002/bmc.2981Administration of DMT in Psychedelic Therapeutics (2022 review): https://doi.org/10.1007/s00213-022-06065-0LISTEN ONSpotify - https://open.spotify.com/show/5m3Gta5MtIYdk59pb2GJ7MApple - https://podcasts.apple.com/ie/podcast/the-giants-shoulder/id1752486249SKOOLWant a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/aboutFOLLOW EVANhttps://x.com/evan_mcglTIMESTAMPS0:00:00 Trailer0:02:15 50 Years Chasing One Molecule0:06:37 Huxley, Osmond and the Birth of "Psychedelic"0:08:01 The Schizotoxin Hypothesis That Started It All0:10:54 Finding DMT in Everyone, Not Just Patients0:11:56 How the War on Drugs Killed the Research0:16:39 The 40 Years of Research We Lost0:18:36 "Have You Ever Taken It Yourself?"0:19:20 Inside the Locked Psychedelic Cabinet0:20:22 The Overabundance He Didn't Want to Waste0:22:51 Why He Won't Describe What He Saw0:23:38 Set, Setting and the Expectancy Problem0:27:16 Dennis McKenna Has Never Seen a Machine Elf0:28:31 "Machine Elf" Was a Marketing Term0:30:40 The Tryptamine Family Tree Explained0:34:21 Bufotenine, 5-MeO-DMT and the Blood-Brain Barrier0:38:36 DMT as a Working Neurotransmitter0:41:34 "DMT Is the Missing Neurotransmitter"0:44:56 You Have Two Brains - and the Gut Makes More0:46:29 Pushing Back on Gallimore's Alien World0:54:04 96% Say the Entity Was Conscious0:57:52 Did the Caveman Experience an Alien?0:59:07 "These Are Not Real Elves"1:06:40 Are Some People Immune to DMT?1:10:51 You Can't Build Tolerance to Your Own Neurotransmitter1:15:46 The Receptors Hiding Inside Your Neurons1:24:24 What a Psychedelic Overdose Actually Is.....Email for sponsorship enquiries: [email protected]
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  #154 Meet The Greatest End-Of-Life Scientist You’ve Never Heard Of 11.09.2026 1ч 26мин

  🧠 JOIN THE GIANT'S SHOULDER FAMILYBecome a YouTube Member for exclusive episodes, early access + ad-free viewing 👇https://www.youtube.com/@thegiantsshoulder/joinAlexander Batthyány is the philosopher and psychologist who turned a deathbed anecdote into a science. He ran the first modern study of paradoxical lucidity, co-authored the field's founding definition with Bruce Greyson, and has now collected around 450 cases of severely demented patients unexpectedly getting their memory, speech and personality back. Victorian doctors documented the phenomenon at length and called it "lightening up before death"; twentieth-century medicine stopped writing it down because there was no way to phrase it in a case study. He is now working with a group at the Mayo Clinic to put cameras in patients' rooms so the episodes stop being missed. In one case a woman came back for two hours, discussed her own diagnosis, died — and imaging taken immediately afterwards showed no change whatsoever.SPONSORSGet One Month Free of Consensus (The Best Ai Science Tool) - https://get.consensus.app/we00d2cmjpqeGS EPISODES MENTIONEDRick Strassman - Meet The Father Of Modern DMT Research: https://youtu.be/KeAZOj7tYscAndrew Gallimore - No.1 DMT Neurobiologist: Alien Worlds, DMT Entity Encounters, Attractor States and Consciousness: https://youtu.be/USgWrxEFWDAGUEST LINKSX: https://x.com/Alxdr_BatthyanyGoogle Scholar: https://scholar.google.com/citations?user=VRL8CPYAAAAJPersonal Site: https://sites.google.com/view/alexanderbatthyany/startViktor Frankl Institute Vienna: https://www.viktorfrankl.org/Threshold (2023): https://us.macmillan.com/books/9781250782298/threshold/Psychology Today - Magic Mushrooms and Terminal Lucidity: https://www.psychologytoday.com/us/blog/consciousness-and-meaning-at-lifes-end/202607/magic-mushrooms-and-terminal-lucidityBatthyany & Greyson (2021), Spontaneous Remission of Dementia Before Death: https://med.virginia.edu/perceptual-studies/wp-content/uploads/sites/360/2021/04/terminal-lucidity-PC.pdfSKOOLWant a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/aboutFOLLOW EVANhttps://x.com/evan_mcglTIMESTAMPS0:00:00 Trailer0:02:29 What Terminal Lucidity Actually Is0:05:33 Why He'd Rather Call It "Paradoxical Lucidity"0:06:01 "Call Your Grandma - She's Back Again"0:09:11 The Victorians Documented It, Then Medicine Stopped0:10:55 "We Saw It, But We Didn't Write It Down"0:12:58 Frankl's Rule: Treat Them As Fully Present0:17:35 What Brain Age Was She Speaking From?0:18:36 "It Was All As If In A Fog"0:21:11 The Wife Who Filmed It So People Would Believe Her0:25:40 The Art Historian Who Gave Back His Books0:30:27 Is It Comforting For Families, Or Crueller?0:32:02 The Three Shocks Every Family Goes Through0:38:05 450 Cases And Counting0:41:29 Does It Have Anything To Do With Death At All?0:45:12 Steven Pinker: "You're Seeing Figures In Clouds"0:47:10 "Everywhere And Nowhere"0:49:47 They Overdosed Her On Psilocybin. She Woke Up.0:51:37 She Got Her Sense Of Humour Back0:55:18 Dresden: The Brain Hadn't Changed At All0:56:37 "Some Of Our Personhood Is Platform Independent"1:02:40 Near-Death Experiences vs Paradoxical Lucidity1:05:52 Rick Strassman, DMT And Neuroprotection1:11:22 "How Can We Get Them Out?"1:20:20 When Vienna Gave Psychiatric Patients Malaria.....Email for sponsorship enquiries: [email protected]
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  #153 - Meet The Neuroscientist Who Does Recreational Heroin 07.09.2026 1ч 14мин

  🧠 JOIN THE GIANT'S SHOULDER FAMILYBecome a YouTube Member for exclusive episodes, early access + ad-free viewing 👇 https://www.youtube.com/@thegiantsshoulder/joinCarl Hart is a human drug scientist — the Mamie Phipps Clark Professor of Psychology in Psychiatry at Columbia University and Chair of its Department of Psychology, who runs one of the very few laboratories on earth licensed to give people real doses of crack cocaine, methamphetamine and MDMA. His volunteers live inside a sealed four-room lab for weeks at a time, originally built for NASA to study astronauts, with no contact with the outside world while he measures their sleep, their food intake and how much they speak. He started that work believing drugs were what had gone wrong in neighbourhoods like the one he grew up in. Thirty years of data refused to agree with him.Expect to learn why there is no such thing as drug addiction in a rat, why "hard drugs" is a category the human body doesn't recognise, why he refuses to use the word "psychedelic", how one extra methyl group is the only difference between methamphetamine and the main ingredient in Adderall, why psychiatry still runs on a theory formalised in 1967 when only six neurotransmitters were known, what heroin actually feels like and why the real danger is constipation rather than overdose, why addiction tracks access rather than pharmacology, and much more…SPONSORSGet Jenni Your Intelligent Research Assistant (GIANT20 for 20% off) - http://jenni.ai/?utm_source=youtube&utm_medium=inf&utm_campaign=thegiantsshoulderGS EPISODES MENTIONEDDavid Luke - Meet the Professor of Paranormal Consciousness - DMT Entities, Telepathy Tapes & OBE's: https://youtu.be/qLKD1gt1X5oGUEST LINKSColumbia Psychiatry Profile: https://www.columbiapsychiatry.org/profile/carl-hart-phdPersonal Website: https://drcarlhart.com/X: https://x.com/drcarlhartDrug Use for Grown-Ups: Chasing Liberty in the Land of Fear: https://en.wikipedia.org/wiki/Drug_Use_for_Grown-UpsHigh Price: A Neuroscientist's Journey of Self-Discovery: https://en.wikipedia.org/wiki/High_Price_(book)FOLLOW EVANhttps://x.com/evan_mcglTIMESTAMPS0:00:00 Trailer0:02:16 Why Human Rights Became His Whole Mission0:03:45 "I Believed the Bullshit About Drugs"0:07:42 The Brain-Imaging Studies That Prove Nothing0:10:32 Why "Hard Drugs" Is a Made-Up Category0:12:42 There Is No Such Thing as Addiction in a Rat0:14:18 Put Cocaine on Your Gum and See What Happens0:15:50 Rat Models for Autism, ADHD and Depression0:18:03 How Many Hoops to Give a Human Crack Cocaine0:20:38 "Psychedelic" Is a Political Word, Not a Real Thing0:22:40 Why the One-Receptor Story Is Bullshit0:23:56 Psychiatry Is Still Running on a 1967 Theory0:31:17 One Methyl Group: Meth vs Adderall0:34:41 The Lab NASA Built for Astronauts0:37:45 The Phenomenology Gap Nobody Studies0:39:01 "I Was a Virgin to These Drugs, And Not Even Curious"0:44:14 What Heroin Actually Feels Like0:47:04 The Real Danger Is Constipation0:52:47 The Overdose Myth He's Trying to Destroy0:55:39 Education, Not Harm Reduction0:58:40 Addiction Isn't About Drugs, It's About Access1:01:38 Not Whether to Legalise, But How1:05:30 Dublin's Cocaine Problem, Evan Pushes Back1:06:46 "That's Quite Arrogant of You"1:09:05 The Same Argument That Delayed Emancipation1:12:50 "We Put People on the Moon. This Is Not Complicated.".....Email for sponsorship enquiries: [email protected]
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  #152 - Meet The Biophysicist Who Accidentally Discovered Telepathy 03.09.2026 1ч 38мин

  JOIN THE GIANT'S SHOULDER FAMILYBecome a YouTube Member for exclusive episodes, early access + ad-free viewing👇 https://www.youtube.com/@thegiantsshoulder/joinLuca Turin is a biophysicist who has spent thirty years arguing that the nose reads a molecule's vibrations rather than its shape, published in Nature at twenty-three, and co-wrote the definitive critical guide to perfume with his wife Tania Sanchez. The vibrational theory of olfaction was declared dead twice before he revived it, and he is still waiting for the one experiment that would settle it. His newest result has nothing to do with smell: fruit flies sealed in separate opaque wells, with no sight, sound or scent between them, coordinate their movement anyway — and the coordination vanishes the moment the plate is made of metal. This is a scientist who went looking for anaesthesia and found something that looks like insect telepathy.Expect to learn why creating a smell stimulus is nothing like creating a colour, how a startup elicited smell sensations with ultrasound for the first time in history, why the only two chemical groups in the universe that share one vibration are also the only two that smell of rotten eggs, how a receptor could read vibrations with no lenses or prisms anywhere in your nose, why the famous "trillion smells" figure was a mathematical error, why nobody in pharmacology can predict what a drug will do once it binds, how Google Quantum AI's xenon question led to fruit flies, what happened when the plates were swapped for aluminium, why radio frequency would be the perfect brain-wide reward signal, and much more…SPONSORSDownload the most scientifically rigorous nutrition app MacroFactor! Use code GIANTS for a 2 week FREE trial - https://app.macrofactor.com/mfgiantsGS EPISODES MENTIONEDEarl K Miller - Meet the MIT Neuroscientist Showing Brain Waves Are the Secret Engine Behind Consciousness: https://youtu.be/7OFb-NG3jIwMarjorie Woollacott - Neuroscientist: "Your Brain Doesn't Create Consciousness" — NDEs, Telepathy and Terminal Lucidity: https://youtu.be/mDWtmfmIUHAGUEST LINKSGoogle Scholar: https://scholar.google.com/citations?user=fgXXdQYAAAAJWi-Fly Project: https://wi-fly.eu/X: https://x.com/LucaTurinSubstack: https://lucaturin.substack.comYouTube: https://www.youtube.com/@lucaturinSKOOLWant a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/aboutFOLLOW EVANhttps://x.com/evan_mcglTIMESTAMPS0:00:00 Trailer0:02:20 Biophysicists Are Dreamers, Biologists Are Doomed0:07:07 The Startup That Triggered Smells With Ultrasound0:12:22 The Rotten-Egg Coincidence That Convinced Him0:18:34 What The Receptor Is Actually Reading0:19:54 Electron Tunnelling, Explained Simply0:23:33 The Trillion-Smells Figure Was A Maths Error0:28:21 What Perfumers Perceive That You Don't0:32:14 Why Every Drug Receptor Might Be Electrical0:33:12 The Mystery Nobody Admits: Drug Efficacy0:39:28 "Cascade" Is A Word That Masks Ignorance0:44:04 The Receptor As A Transistor0:48:40 Google Quantum AI And The Xenon Puzzle0:52:24 Two Years Of Work, A Definite Maybe0:53:55 30 Flies Freeze Like The Guards At Buckingham Palace0:55:28 One Fly Per Well, No Way To Communicate0:56:17 To My Total Astonishment, They Coordinate0:58:45 Metal Plates Kill The Signal0:59:36 The Wi-Fly: A Radio Network For Flies1:11:26 Radical Pairs: How A Fly Could Listen1:16:34 What Is The Brain's Reward Signal?1:19:59 Standing Waves And The Binding Problem1:23:58 Could Humans Ever Do This?1:27:46 Ramanujan And Latent Abilities1:36:16 Giving Fruit Flies DMT.....Email for sponsorship enquiries: [email protected]
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  #151 - Meet the Greatest Lucid Dreaming Scientist You've Never Heard Of 31.08.2026 1ч 19мин

  🧠 JOIN THE GIANT'S SHOULDER FAMILYBecome a YouTube Member for exclusive episodes, early access + ad-free viewing 👇 https://www.youtube.com/@thegiantsshoulder/joinKaren Konkoly is a dream scientist who led the first study to hold a real-time, two-way conversation with a person inside a dream, putting maths problems to sleepers in REM and getting answers back through their eye movements. She is a Marie Curie Postdoctoral Fellow in the Cambridge Consciousness and Cognition Laboratory, completed her PhD in the Paller Cognitive Neuroscience Laboratory at Northwestern University, and has spent her career building tools to engineer dreams — from targeted lucidity reactivation for narcolepsy nightmares to planting unsolved problems into REM sleep. She has also asked a dream character to swap bodies with her, and woken up inside it. This is the strangest conversation we have had on the channel.Expect to learn how scientists prove someone is awake inside a dream, why you still cannot fly in your own dream even when you know it is a dream, what happened when Karen swapped bodies with a dream character, whether time really slows down while you sleep, why practising darts in a lucid dream works about as well as practising awake, what galantamine and acetylcholine actually do to REM sleep, the exact protocol for having your first lucid dream, why Karen no longer believes lucidity is the key to consciousness, and much more…SPONSORSGet One Month Free of Consensus (The Best Ai Science Tool) - https://get.consensus.app/we00d2cmjpqeGS EPISODES MENTIONEDDavid Spiegel - World's Greatest Hypnosis Scientist Hijacks My Mind Live On Camera!: https://youtu.be/eCtRBZHIsgQGUEST LINKSPersonal Website: https://www.karenkonkoly.com/Google Scholar: https://scholar.google.com/citations?user=teYHEFIAAAAJ&hl=enCambridge Consciousness & Cognition Lab: https://www.ccc-lab.org/Dust Systems (Dream Engineering): https://www.dust.systems/people/karen-konkolyX: https://x.com/KarenKonkolyLISTEN ONSpotify - https://open.spotify.com/show/5m3Gta5MtIYdk59pb2GJ7MApple - https://podcasts.apple.com/ie/podcast/the-giants-shoulder/id1752486249SKOOLWant a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/aboutFOLLOW EVANhttps://x.com/evan_mcglTIMESTAMPS0:00:00 Trailer0:03:18 What Lucid Dreaming Actually Is0:05:37 Wake Back To Bed: The 4am Method0:06:40 Why You Still Can't Fly In Your Own Dream0:09:20 How You Prove Someone Is Lucid In A Dream0:11:53 Are The Sleep Stages Even Real?0:15:28 When A Dream Dissolves But You Don't Wake Up0:19:19 The Reality Check You Can Do Tonight0:21:00 Does Time Run Slower Inside A Dream?0:24:45 Trying And Failing To Become Her Dog0:26:10 Swapping Bodies With A Dream Character0:27:51 Is Lucidity A Glitch In Consciousness?0:33:37 Hyperphantasia And Maladaptive Daydreaming0:37:53 Practising Darts While You're Asleep0:41:52 When Lucid Dreaming Is A Bad Idea0:46:09 Why A Giraffe Can't Appear While You're Awake0:49:54 Galantamine, Acetylcholine And Dream Drugs0:52:17 The Squat Experiment0:58:38 The Full Protocol, Step By Step1:04:55 What This Teaches Us About Consciousness1:09:15 Who Are Your Dream Characters?1:12:55 "You're Not You"1:14:41 Hypnosis, David Spiegel And Lucid Dreaming1:18:20 What She's Working On Next.....Email for sponsorship enquiries: [email protected]
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  #150 - World's Greatest Hypnosis Scientist Hijacks My Mind Live On Camera! 27.08.2026 1ч 34мин

  🧠 JOIN THE GIANT'S SHOULDER FAMILYBecome a YouTube Member for exclusive episodes, early access + ad-free viewing 👇https://www.youtube.com/@thegiantsshoulder/joinDavid Spiegel is the world's leading hypnosis scientist — fifty years at Stanford spent proving that trance is a measurable brain state rather than a stage trick, across thirteen books, four hundred papers and roughly seven thousand patients hypnotised personally. I told him to his face that I thought his entire field was a scam, so he ran the hypnotisability test on me live on camera, my left arm floated off the desk and stopped obeying me for the next forty minutes, and he scored me seven out of ten.Expect to learn what hypnosis actually is and the three components it breaks down into, how stage hypnotists secretly screen their audiences before the show even starts, what changes in three separate brain networks the moment you go under, why "suggestibility" is the wrong word and cognitive flexibility is the right one, how hypnotised subjects cut their brain's electrical response to pain by 50%, why one in four smokers quit after a single session, the two very different childhoods that both produce highly hypnotisable adults, why eight-year-olds are the most hypnotisable people alive, how Rory McIlroy used self-hypnosis to break a seven-year Masters curse, what it feels like to have your own arm stop belonging to you, and much more…SPONSORSTry Reveri, Dr David Spiegel's Self-Hypnosis App (use code SPIEGEL20 for your discount) - https://reverihealth.app.link/e/spiegelGet One Month Free of Consensus (The Best Ai Science Tool) - https://get.consensus.app/we00d2cmjpqeGUEST LINKSStanford Profile: https://profiles.stanford.edu/david-spiegelReveri: https://www.reveri.com/Reveri on X: https://x.com/reveri_healthStanford Center on Stress and Health: https://med.stanford.edu/stresshealthcenter.htmlTrance and Treatment (his clinical textbook): https://www.appi.org/Products/Hypnosis/Trance-and-Treatment-Second-EditionSKOOLWant a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/aboutFOLLOW EVANhttps://x.com/evan_mcglTIMESTAMPS0:00:00 Trailer0:02:27 Who Is David Spiegel?0:03:39 What Hypnosis Actually Is0:05:37 Why He Calls Stage Shows "Dumb Shows"0:06:29 How Hypnotists Secretly Screen The Audience0:09:08 The Student Who Relived Being A Newborn0:10:46 What Hypnosis Does To Three Brain Networks0:13:23 It's Not Suggestibility, It's Cognitive Flexibility0:16:12 Cutting The Brain's Pain Signal By 50%0:17:05 One In Four Quit Smoking In A Single Session0:18:33 The Meditator Whose Migraines Vanished0:22:36 Why Hypnotisability Is Partly Genetic0:23:54 The Two Childhoods That Make You Hypnotisable0:27:16 Hypnosis, Flow States And Peak Performance0:32:54 How Rory McIlroy Broke His Masters Curse0:38:05 Why You Can Forget Your Own Name0:44:29 Filtering The Hurt Out Of Pain0:55:00 The Hypnotisability Test, Live On Camera1:00:15 "It's Actually Going Up"1:08:52 Evan Scores 7 Out Of 101:18:42 Trying To Erase The Number Four1:31:04 "Please Don't Do This On My Other Arm".....Email for sponsorship enquiries: [email protected]
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  #149 - Meet The Father Of Modern DMT Research 24.08.2026 1ч 21мин

  🧠 JOIN THE GIANT'S SHOULDER FAMILYBecome a YouTube Member for exclusive episodes, early access + ad-free viewing: https://www.youtube.com/@thegiantsshoulder/joinRick Strassman is the psychiatrist who ran the first new American psychedelic research in a generation — five years of DMT studies at the University of New Mexico, the first rating scale ever built specifically to measure a psychedelic experience, and the book that made DMT famous. DMT: The Spirit Molecule sold a quarter of a million copies and effectively created machine-elf culture. Thirty years on, he is the most sceptical man in the room about what those entities actually are.Expect to learn why your brain spends energy importing DMT across the blood-brain barrier, why the pineal gland story he made famous fell apart, how brain DMT sits at the same concentration as serotonin and dopamine, why DMT floods the visual cortex of a dying brain, why a molecule that shrinks strokes and protects kidneys should not be psychedelic at all, what the endomatrix is and why it raises the simulation question, why he now thinks psychedelics are super placebos, what a DMT entity actually is and why talking to one is like talking to an AI, how you would actually test whether the entities are real, why only one scientist on Earth is studying endogenous DMT, and much more…SPONSORSGet Jenni Your Intelligent Research Assistant (GIANT20 for 20% off) - http://jenni.ai/?utm_source=youtube&utm_medium=inf&utm_campaign=thegiantsshoulderJoin the Outskill AI Mastery Sprint (Free This Weekend) - https://links.outskill.com/GIASHOULAUG2GS EPISODES MENTIONEDSteven Barker - Meet The World's Greatest Endogenous DMT Psychedelic Scientist You've Never Heard Of: https://youtu.be/gTc5QjyZuvYDavid Luke - Meet the Professor of Paranormal Consciousness - DMT Entities, Telepathy Tapes & OBE's: https://youtu.be/qLKD1gt1X5oDeborah Mash - Meet The Ibogaine Psychedelic Scientist Who First Unravelled Its Big Mystery: https://youtu.be/z7eRtXV6ptARobin Carhart-Harris - No. 1 Psychedelic Scientist: The Entropic Brain Hypothesis, Consciousness & DMT Entities: https://youtu.be/t-GkE4YtLRkAndrew Gallimore - No.1 DMT Neurobiologist: Alien Worlds, DMT Entity Encounters, Attractor States and Consciousness: https://youtu.be/USgWrxEFWDAGUEST LINKSOfficial Site: https://www.rickstrassman.com/Books & Publications: https://www.rickstrassman.com/publications/Substack: https://rickstrassman.substack.com/YouTube: https://youtube.com/c/RickStrassmanBiosynthesis and Extracellular Concentrations of DMT in Mammalian Brain (Dean et al., Scientific Reports 2019): https://www.nature.com/articles/s41598-019-45812-wTIMESTAMPS0:00:00 Trailer0:04:31 The First Legal DMT Studies in a Generation0:07:41 The Bomb-Maker Who Became a Psychedelic Scientist0:14:13 The Iron Curtain Reason We Know DMT Works0:22:32 Why Your Brain Spends Energy Importing DMT0:28:26 Your Brain Makes DMT at Serotonin Levels0:29:26 DMT Floods the Dying Brain's Visual Cortex0:30:28 Stroke, Kidneys and Heart — DMT as a Survival Molecule0:32:39 The $64,000 Question Nobody Can Answer0:36:33 Does DMT Regulate How Real Reality Feels?0:39:32 Only One Person on Earth Studies This0:43:52 The Endomatrix and the Simulation Question0:49:48 "Psychedelics Are Super Placebos"0:55:12 The Man Who Wrote Down "Bananas Are Really Yellow"1:03:50 The Barking Patient — Entities as Dream Logic1:05:42 Talking to Entities Is Like Talking to an AI1:06:40 The Prime Number Test for Proving Entities Are Real1:13:36 Half His Volunteers Met Beings — And a Conscious Apartment1:18:08 "Your Brain On Drugs" vs Another Dimension1:26:58 The Entities That Curse You1:29:09 "Have You Started Yet?" — The Man Immune to DMT1:33:30 Why DMT Is the Only Psychedelic Without Tolerance1:36:12 Blocking 5-HT1A Tripled the Effect — Buried 30 Years1:39:06 Aphantasia and Seeing For the First Time.....Email for sponsorship enquiries: [email protected]
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  #148 - Meet The Ibogaine Psychedelic Scientist Who First Unravelled Its Big Mystery 20.08.2026 1ч 2мин

  🧠 JOIN THE GIANT’S SHOULDER FAMILYBecome a YouTube Member for exclusive episodes, early access + ad-free viewing: https://www.youtube.com/@thegiantsshoulder/joinDeborah Mash is a neuropharmacologist who holds the first FDA licence ever granted to give ibogaine to a human being, built one of America's largest brain banks, and discovered noribogaine — the metabolite now entering its first US clinical trial. She has spent over thirty years on a drug that appears to interrupt addiction after a single dose. This April a US president named it specifically. This is the scientist who was right three decades early.Expect to learn what Trump's executive order actually changes for ibogaine, why Sasha Shulgin put ibogaine in a box of its own, how noribogaine blocks nicotine, alcohol, cocaine and opioid use in animal models, why ibogaine holds the brain's neuroplasticity window open for four weeks when ketamine manages days, why some patients get the full therapeutic benefit with no psychedelic experience at all, why the reported ibogaine deaths are almost impossible to interpret, why more than 80% of her patients said they never wanted to repeat it, and much more...SPONSORSGet Jenni Your Intelligent Research Assistant (GIANT20 for 20% off) - http://jenni.ai/?utm_source=youtube&utm_medium=inf&utm_campaign=thegiantsshoulderJoin the Outskill AI Mastery Sprint (Free This Weekend) - https://links.outskill.com/GIASHOULAUG2GS EPISODES MENTIONEDDavid Nutt - Meet the Neuroscientist Fired For Exposing the Truth! Dr David Nutt: https://youtu.be/BLk6a5Vb2O0David Nutt - Neuroscientist Ranks Every Drug By How Hard They Are to Quit! Tier List: https://youtu.be/G-OZ_UBGvvoGUEST LINKSUniversity of Miami Faculty Profile: http://neurology.med.miami.edu/about-us/faculty-list/deborah-c-mash-ph-dX: https://x.com/drdeborahmashGoogle Scholar: https://scholar.google.com/citations?user=4383E7wAAAAJ&hl=enDemeRx: https://www.demerx.com/team/deborah-c-mash-phd/2018 Frontiers in Pharmacology paper (St. Kitts cohort): https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2018.00529/fullWant a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/aboutFOLLOW EVANhttps://x.com/evan_mcglTIMESTAMPS0:00:00 Trailer0:02:00 Why Ibogaine Is Suddenly Everywhere0:02:22 Trump's Executive Order and What It Actually Does0:05:55 The Drug That Breaks the Cycle of Addiction0:08:07 Why One Drug Treats Addiction, Depression and Trauma0:11:30 Noribogaine: The Metabolite Nobody Talks About0:14:20 The Real Risks Nobody Reports Properly0:16:36 How Ibogaine Became a Vast Underground Experiment0:17:44 Veterans, Brain Trauma and the Testimonials0:22:55 The Master Molecule: Why Ibogaine Stands Alone0:23:30 Sasha Shulgin Draws Four Boxes0:26:48 Is a Psychedelic Just a Hard Reboot?0:28:11 Four Weeks of Neuroplasticity, Longer Than Anything Else0:28:44 Fast, Slow and Ultra-Rapid Metabolisers0:31:39 The First Patient in St. Kitts, Decades Later0:34:35 Do You Need the Trip to Reach the Destination?0:35:05 One Molecule, Every Addiction0:37:39 Miami Vice and the Bodies at the Morgue0:41:18 The Man Who Slept Through His Own Trip0:44:11 Why America Will Lead on Ibogaine0:47:51 Dual Dosing: The Second Stage of the Rocket0:54:52 Why More Than 80% Never Want to Repeat It0:57:33 What Would Ibogaine Do to a Healthy Brain?0:58:18 Why She's Never Taken Ibogaine0:59:39 Psychedelics, Longevity and Ageing Brains......Email for sponsorship enquiries: [email protected]
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  #147 - No. 1 Mitochondria Psychobiologist: "Mitochondria Create Consciousness and Near-Death Experiences" 17.08.2026 1ч 3мин

  Get Jenni Your Intelligent Research Assistant (GIANT20 for 20% off) - http://jenni.ai/?utm_source=youtube&utm_medium=inf&utm_campaign=thegiantsshoulderJoin the Outskill AI Mastery Sprint (Free This Weekend): https://links.outskill.com/GIASHOULAUG2Want a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/aboutMartin Picard is a mitochondrial psychobiologist at Columbia University who just won the inaugural $1.5 million Baszucki Prize for a new theory of life. His radical claim: consciousness doesn't just run on energy, it might actually be made of it, generated inside your mitochondria rather than your brain.Expect to learn why calling mitochondria "the powerhouse of the cell" does them a disservice, how mitochondria might generate consciousness rather than just power the brain that has it, why some of history's most rigorous physicists ended up believing consciousness is more fundamental than matter, how psychedelics might work by reshaping the way energy is patterned through your body, why grey hair can reverse itself within weeks of a stressful period lifting, how a simple blood test might one day predict whether you're about to have a good or bad trip, why "no drug actually heals you" and what does instead, and much more.Timestamps:0:00:00 Trailer0:02:00 What Actually Keeps You Alive (Not What You Think)0:04:40 Why There's No Experience Without Energy Flow0:07:11 Are You Conscious Because of Matter, or Despite It?0:10:13 Why History's Greatest Physicists Became Idealists0:17:17 The Doctor Who Watched Patients Come Back From Death0:22:09 Don Hoffman and the Day the Beach Disappeared0:24:12 What Actually Triggers a Near-Death Experience0:24:51 You Are an Eddy in a River of Consciousness0:31:59 Bernardo Kastrup's Idealism, Tested Live0:33:34 Could We Scan Your Energy and Predict Your Mind?0:39:37 Stop Calling Mitochondria "The Powerhouse"0:40:03 Your Cells Are Basically Tiny GPUs0:41:04 How Psychedelics Might Rewrite Your Energy Pattern0:49:10 The Study Testing Whether Psilocybin Changes Your Mitochondria0:52:06 "It's Not the Drug That Heals You"0:52:38 A Blood Test That Predicts Your Best (and Worst) Trip0:57:27 The Psychedelic Paradox: Less Brain, More Experience0:58:57 Aldous Huxley's "Reducing Valve" Theory of the Brain1:02:03 "The Brain Is Overrated"... Email for sponsorship enquiries: [email protected] Episodes Mentioned:Robin Carhart-Harris - No. 1 Psychedelic Scientist: The Entropic Brain Hypothesis, Consciousness & DMT Entities: https://youtu.be/t-GkE4YtLRkGuest Links:Columbia Faculty Profile: https://www.columbiapsychiatry.org/profile/martin-picard-phdPersonal Website: https://www.martinpicard.energy/X (Twitter): https://x.com/MitoPsychoBioGoogle Scholar: https://scholar.google.com/citations?user=IG2t_uMAAAAJ&hl=enMitochondrial Psychobiology Lab: https://www.picardlab.org
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  #146 - Meet The Greatest Bioelectricity Scientist You've Never Heard Of 13.08.2026 1ч 15мин

  Try Mind Lab Pro, The Universal Nootropic For A Sharper Brain: https://www.mindlabpro.com/?a_aid=67fd1cb8d9ad3&a_bid=6d45f5c3Join The Outskill Claude Mastery Sprint (2 Days, Free): https://links.outskill.com/GIASHOULAUG2Want a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/aboutMin Zhao is the UC Davis professor whose lab discovered the first genes ever found in electrical signalling — proof that every cell in your body runs on a current, not just your brain. He can reverse the polarity of a field and watch a living cell physically turn around and walk the other way.Expect to learn why every wound in your body generates its own measurable electric current, how a single postdoc's "failed" experiment revealed a force that overrides genetics, how reversing an electric field can make a cell physically turn around mid-migration, how a damaged potato generates the same electrical signal that guides wound healing in humans, why Min stops short of fully agreeing with Michael Levin on whether cells count as agents, and where the fight between bioelectricity and genetics currently stands.Timestamps0:00:00 Trailer0:02:20 What Everyone Gets Wrong About Wound Healing0:07:20 Your Skin Is Secretly Electric (And So Is Everything Alive)0:11:09 The 200-Year-Old Discovery Hiding in Every Wound0:15:19 The Postdoc Result That Changed the Whole Lab0:19:19 How Do Cells Know Where to Grow? (Five Fingers, Not Six)0:21:19 The Potato Experiment That Reveals How Infections Start0:25:24 Reverse the Field, Watch a Cell Turn Around0:38:10 The Bioelectricity Nobody Taught in Biology Class0:44:17 Is Bioelectricity More Fundamental Than Genes?0:45:33 "No Electricity, No Life"0:49:14 When Electric Fields Override Genetics Entirely1:03:40 Michael Levin's Xenobots, Debated1:12:22 Do Cells Have Agency? The Fuzziest Question in Biology1:15:16 To Be Continued... (Members Get the Rest)... Email for sponsorship enquiries: [email protected] Episodes MentionedMichael Levin — Michael Levin: Bioelectricity, Morphogenesis, Platonic Spaces & Xenobots: https://www.youtube.com/watch?v=LTBZRVKUwyMPhilip Ball — Philip Ball: "Biology Is Infinitely Weirder Than We Thought": https://www.youtube.com/watch?v=9SseGx0R0fYDenis Noble — Denis Noble: Evolution Has Purpose, Cell Consciousness & Why The Last 70 Years of Genetics Is Wrong: https://www.youtube.com/watch?v=xqw-DaWVK24Michael Levin & Earl Miller — Michael Levin & Earl Miller: Platonic Space of Minds, Bioelectricity, Cell Intelligence & Neurobots: https://www.youtube.com/watch?v=6mU5nN5nlLAGuest LinksUC Davis Faculty Profile: https://health.ucdavis.edu/dermatology/faculty/zhao.htmlZhao Lab (UC Davis Dermatology): https://health.ucdavis.edu/dermatology/research/lab/zhao.htmlGoogle Scholar: https://scholar.google.com/citations?user=G7-zWBcAAAAJ&hl=enNeuroengineering at UC Davis: https://neuroengineering.ucdavis.edu/people/min-zhao-md-phdUC Davis Profiles (Publications): https://profiles.ucdavis.edu/min.zhao
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  #145 - Meet the Ibogaine Neuroscientist Revolutionising Addiction Treatment 10.08.2026 1ч 31мин

  Get One Month Free of Consensus (The Best Ai Science Tool): https://get.consensus.app/we00d2cmjpqeUpgrade Your Shaving Experience With Henson (100 FREE BLADES): https://hensonshaving.com/thegiantsshoulderWant a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/aboutKirsten Cherian is the Stanford neuropsychologist who gave Special Forces veterans with traumatic brain injuries a single dose of ibogaine — a psychedelic root used in African shamanic ritual for millennia — and watched their injury scores collapse from severe to normal in a month. It's a weak agonist for nearly every receptor in the body, yet it somehow delivers a tailor-made result to each person — a form of pharmacology science has never seen before.Expect to learn why veteran suicide outpaces combat deaths, how one dose collapsed PTSD, depression, and anxiety at once, why users describe their brains being "defragged," a researcher's 12-hour "conversation" with the ibogaine molecule itself, the bizarre phenomenon of "DMT blocking" by hostile entities, why ibogaine has no single receptor target — "matrix pharmacology," how brain age dropped by over a year in a single month, and why the results contradict science's leading theory of consciousness.Timestamps0:00:00 Trailer0:02:11 How This Ibogaine Study For Veterans Began0:04:06 Veteran Suicide Now Outpaces Combat Deaths0:07:31 The 30-Veteran Study With Staggering Effect Sizes0:12:22 Ibogaine Isn't A Trip, It's A Waking Dream0:13:14 Vivid Trip Imagery: Slideshows And "Defragged" Brains0:15:02 Reconciling Trauma By Talking To The Dead0:20:01 What A Bad Ibogaine Trip Actually Looks Like0:24:50 Purging "Black Demons" In A Room Full Of Strangers0:27:23 The Scientist Who Talked To The Ibogaine Molecule0:33:36 Why Elite Special Forces Veterans Still Broke0:34:30 DMT Blocking: When Entities Refuse To Let You In0:41:22 The Psilocybin Researcher Who Believes In Telepathy0:43:00 Why Ibogaine Has No Single Target In The Brain0:46:25 The 1920s Thought Experiment That Proves We're Too Skeptical0:49:38 Ibogaine As A Full-System Diagnostic, Not A Drug1:03:36 Measurable Brain Change From An African Tree Fruit1:05:19 Brain Age Dropped Over A Year After One Dose1:17:21 The Finding That Contradicts The Leading Theory Of Consciousness1:20:28 If Ibogaine Research Got A Blank Billion-Dollar Check1:23:21 Could Ibogaine Help Parkinson's And ALS Patients?... Email for sponsorship enquiries: [email protected] Episodes MentionedDalibor Sames — Meet The Greatest Ibogaine Psychedelic Scientist You've Never Heard Of: https://www.youtube.com/watch?v=K9whp_wtCocAndrew Gallimore — No.1 DMT Neurobiologist: Alien Worlds, DMT Entity Encounters, Attractor States and Consciousness: https://www.youtube.com/watch?v=USgWrxEFWDADavid Luke — Meet the Professor of Paranormal Consciousness - DMT Entities, Telepathy Tapes & OBE's: https://www.youtube.com/watch?v=qLKD1gt1X5oMatthew Johnson — Consciousness Expert Explains The 5 Levels Of The Psilocybin Experience: https://www.youtube.com/watch?v=FHyy3aW09skRobin Carhart-Harris — No. 1 Psychedelic Scientist: The Entropic Brain Hypothesis, Consciousness & DMT Entities: https://youtu.be/t-GkE4YtLRkGuest LinksStanford Profile: https://profiles.stanford.edu/kirsten-cherianStanford Brain Stimulation Lab: https://bsl.stanford.edu/MISTIC Study (Nature Medicine, 2024): https://pubmed.ncbi.nlm.nih.gov/38182784/ResearchGate: https://www.researchgate.net/profile/Kirsten-CherianVETS — Veterans Exploring Treatment Solutions: https://vetsolutions.org/
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  #144 - Consciousness Expert Ranks Every Drug By Intensity Of Subjective Experience 06.08.2026 2ч 6мин

  Download the most scientifically rigorous nutrition app MacroFactor! Use code GIANTS for a 2 week FREE trial: https://app.macrofactor.com/mfgiantsTry Mind Lab Pro, The Universal Nootropic For A Sharper Brain: https://www.mindlabpro.com/?a_aid=67fd1cb8d9ad3&a_bid=6d45f5c3Andrés Gómez Emilsson is a consciousness mathematician at the Qualia Research Institute, and he's back for round two of ranking altered states of consciousness by sheer intensity. He and Evan spend two hours ranking every substance and practice they can think of — arguing that ibogaine may be the most ethically urgent drug on Earth, that a hardcore meditation retreat can rival 5-MeO-DMT, and that an obscure nootropic produces psychedelic visuals through a mechanism nobody understands.Expect to learn why ibogaine seems to "scan" your whole nervous system instead of hitting one receptor, how advanced jhana meditation can go toe-to-toe with 5-MeO-DMT in depth, why ordinary DMT produces far more alien entity encounters than its "stronger" cousin, the topology behind why feeling like God and feeling like there's no self are almost the same state, why cannabis's real danger isn't addiction but a specific schizophrenia risk in young men, how combining LSD and ketamine produces "freewheeling hallucinations" you can consciously direct, why mescaline might be the best nootropic for doing actual math yet never caught on, and where MDMA, salvia, and a little-known nootropic called coluracetam land on the scale, and much more…Timestamps0:02:53 Ibogaine0:17:28 5-MeO-DMT0:36:05 Meditation0:46:33 DMT0:58:41 Cannabis1:05:15 Psilocybin1:11:41 Ayahuasca1:18:42 Coluracetam1:21:09 MDMA1:29:26 Salvia1:44:21 Ketamine1:54:37 Mescaline1:58:48 LSD...... Email for sponsorship enquiries: [email protected] a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/aboutGS Episodes MentionedDavid Nutt — Neuroscientist Ranks Every Drug By How Hard They Are to Quit! Tier List Part 2: https://www.youtube.com/watch?v=CEgbv6IHYaYMichael Levin & Earl Miller — Platonic Space of Minds, Bioelectricity, Cell Intelligence & Neurobots: https://www.youtube.com/watch?v=6mU5nN5nlLAGuest LinksQualia Research Institute: https://qri.orgQualia Computing (blog): https://qualiacomputing.comSubstack: https://andrsgmezemilsson.substack.comX (Twitter): https://x.com/algekalipso
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  #143 - Meet the World's Greatest Imagination Neuroscientist You’ve Never Heard Of 03.08.2026 1ч 42мин

  Upgrade Your Shaving Experience With Henson (100 FREE BLADES): https://hensonshaving.com/thegiantsshoulderWant a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/aboutDr. Reshanne Reeder is a cognitive neuroscientist at the University of Liverpool and creator of the Ganzflicker — a flickering screen that makes most people hallucinate complex scenes within a minute, no drugs required. Her research suggests hallucinations themselves are just disordered mental imagery, and that the most vividly imaginative among us may be the closest normal-range group to a psychotic break.Expect to learn why a simple red-and-black flicker makes most people hallucinate faces and landscapes within a minute, the accidental lab discovery that led to the Ganzflicker experiment, why she believes hallucinations are simply "disordered mental imagery," why psychedelic and clinical hallucinations come from entirely different brain mechanisms, the 1960s art device built to replace the television, why almost nobody hallucinates their own phone, how aphantasia may carry a hidden cost to face recognition, how she's trying to predict psychosis risk years before it ever develops, and much more…Timestamps0:00:00 Trailer0:02:29 How She Discovered Imagery Isn't One Thing0:08:43 Can You Decode Images in an Aphantasic's Brain?0:10:37 The Truth About "Unconscious" Mental Imagery0:16:01 Imagery vs Imagination: Why They Aren't the Same Word0:18:55 Imagery, Perception, Hallucination, Dreaming: Where's the Line?0:20:36 The Hyperphantasics Who Project Images Into the Real World0:22:23 Her Bold Claim: Hallucinations Are Disordered Imagery0:23:37 Can Aphantasics Hallucinate on Psychedelics?0:27:55 The DMT Study Where 90% Said It Felt More Real Than Reality0:29:39 Why Mental Imagery Breaks the Predictive Brain Theory0:32:21 The Irish Castle Test: Are Mental Images Just Priors?0:38:58 She Made People See Faces in Pure Random Noise0:42:04 The Illusion That Turns Faces Into Monsters0:45:48 Why Aphantasia Might Come With a Face-Recognition Cost0:47:35 His Sister Went 31 Years Without Knowing She Had Aphantasia0:49:59 The Accidental Origin Story of Ganzflicker0:51:26 The 1700s Origin of the "Whole Field" Hallucination Effect0:57:41 "I See a Lighthouse": The Moment Ganzflicker Was Born1:00:28 Why Aphantasics Barely Hallucinate on Ganzflicker1:05:31 The Sharp Cliff Between Zero and Weak Mental Imagery1:12:30 Why Nobody Hallucinates Their Phone1:19:45 The Hypnosis Session That Left His Arm Frozen in the Air1:22:13 The 1960s "Dream Machine" That Was Supposed to Replace TV1:35:59 Can This Predict Psychosis Before It Happens?...... Email for sponsorship enquiries: [email protected] Episodes MentionedAdam Zeman — The Blind Mind's Eye: How Aphantasia Is Rewriting Consciousness ! Dr Adam Zeman: https://www.youtube.com/watch?v=SgA2up6-BokAlfredo Spagna — Meet The Neuroscientist Proving We Got Imagination & Aphantasia WRONG!: https://www.youtube.com/watch?v=k8SBHefDnEkDavid Luke — Meet the Professor of Paranormal Consciousness - DMT Entities, Telepathy Tapes & OBE's: https://www.youtube.com/watch?v=qLKD1gt1X5oKarl Friston — Meet The Neuroscientist Who Created The Best Universal Theory Of Brain Function: https://www.youtube.com/watch?v=R-IZOFs4qmYAnil Seth — No. 1 Consciousness Expert: Optical Illusions that Prove Reality is a Lie, Emotions, Books and AI!: https://www.youtube.com/watch?v=lOSA06K0l1oGuest LinksUniversity of Liverpool Faculty Page: https://www.liverpool.ac.uk/people/reshanne-reederPersonal Website (Ganzflicker Demo): https://www.reshannereeder.com/Bluesky: https://bsky.app/profile/kerblooee.bsky.socialGoogle Scholar: https://scholar.google.com/citations?hl=en&user=DfdUB3UAAAAJLinkedIn: https://uk.linkedin.com/in/reshanne-reeder-53182123b
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  #142 - Meet the Philosopher Behind Michael Levin's Strangest Idea The - Platonic Space Of Minds 30.07.2026 1ч 20мин

  Check out Scispace: (JNGIANT35: Get 35% off on the Max plan) https://scispace.com/?via=jun1giantshoulderWant a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/aboutDavid Resnik is the NIH's Senior Advisor for Research Integrity and a philosopher of science who has spent his career defending careful, sober naturalism. He just co-authored a paper with biologist Michael Levin arguing that the shape of your body — and maybe your mind — is pulled from a nonphysical space of mathematical forms.Expect to learn why cicadas evolved to emerge only in prime-numbered years to dodge predators, why a mule's infertility comes down to simple odd-and-even chromosome math, why mathematics might be a "free lunch" baked into the universe rather than something we invented, why there may be no real difference between an electron and the equation that describes it, why Michael Levin's leap to calling certain mathematical forms "minds" might be the biggest jump in modern biology, why a Xenobot growing eyes and ears it doesn't need raises the question of where biological information actually comes from, why even a few lines of sorting-algorithm code can behave in ways nobody predicted, and why David thinks it might not matter whether Platonism is literally true, as long as it keeps producing good science.Timestamps0:00:00 Trailer0:02:52 Is Math Discovered or Invented?0:15:48 Why Cicadas Emerge in Prime-Numbered Years0:19:45 Why Mules Can't Reproduce (It's Just Math)0:21:19 Michael Levin's "Free Lunch": Math That Isn't Physical0:24:16 Is Materialism Actually Incomplete?0:29:43 Xenobots: Where Did the Information Come From?0:35:08 Why Do Xenobots Grow Ears and Eyes They Don't Need?0:43:40 The Magnet and Iron Filings Experiment0:45:26 Is There Really a Difference Between an Electron and Math?0:46:40 Michael Levin's "Grand Canyon Jump" to Platonic Minds0:48:03 What Is a Cognitive Light Cone?0:54:26 Cutting a Triangle: What "Ingression" Actually Means0:59:40 Michael Levin's Biological Compiler Idea1:01:27 The Two-Headed Worm and the Eye That Shouldn't Exist1:02:02 A Sorting Algorithm That Does the Unexpected1:05:17 Laplace's Demon and the Limits of Prediction1:09:43 Does It Matter If Platonic Space Is Real?1:16:00 Could AI Access Minds Human Brains Can't?1:17:36 The Limits of Any Mind in the Universe... Email for sponsorship enquiries: [email protected] Episodes MentionedMichael Levin — Michael Levin: Bioelectricity, Morphogenesis, Platonic Spaces & Xenobots: https://youtu.be/LTBZRVKUwyMMichael Levin & Earl Miller — Meet the Scientist Showing Every Cell In Your Body is Conscious!: https://youtu.be/eNi-_2cOVtcJulian Barbour — Meet The Greatest Mathematician You've Never Heard Of: https://youtu.be/LcYdhjcFnzAGuest LinksDavid Resnik — NIH Office of Intramural Research: https://oir.nih.gov/about/leadership-staff/david-resnikLevin & Resnik — "Mind Everywhere" Part One (Biological Theory): https://doi.org/10.1007/s13752-025-00523-6Levin & Resnik — "Mind Everywhere" Part Two (Biological Theory): https://doi.org/10.1007/s13752-025-00524-5David Resnik — ResearchGate: https://www.researchgate.net/profile/David-Resnik-2David Resnik — NIEHS Bioethics: https://www.niehs.nih.gov/research/resources/bioethics/bioethicist
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  #141 - Meet the Neuroscientist Investigating Language and the Platonic Space 27.07.2026 1ч 35мин

  Upgrade Your Shaving Experience With Henson (100 FREE BLADES): https://hensonshaving.com/thegiantsshoulderWant a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/aboutElliot Murphy is a neurolinguist at UTHealth Houston who records language directly from inside the human brain, placing electrodes deep in the cortex of epilepsy patients and watching meaning get built in real time. His claim is unsettling: every time you speak, your brain performs an operation no other cognitive system — and no AI — can do, and the structure of grammar may be something the brain discovers rather than invents.Expect to learn why the phrase "old men and women" proves language breaks the laws of algebra, how "red boat" and "barco rojo" hide the same secret structure, what it means to record single words forming inside a living brain, why the deepest things you feel are impossible to put into words, how one word like "lunch" can be food, an event, and a time all at once, where Elliot stands on Michael Levin's idea that meaning lives in a Platonic space, why he thinks large language models don't understand a word they produce, what really separates human intelligence from pattern-matching, and much more…Timestamps0:00:00 Trailer0:01:56 From Liverpool Bookworm to Brain Scientist0:10:25 The Phrase That Breaks the Laws of Logic0:12:36 Why "Red Boat" and "Barco Rojo" Are Secretly Identical0:15:14 Where Language Actually Lives in Your Brain0:20:02 Recording Single Words Inside a Living Brain0:23:38 The Surgery That Changed How We Study Language0:36:12 Does Anything Else Work Like Language? Even Music?0:40:28 The Feelings No Words Can Ever Reach0:42:19 The Nietzsche Line Elliot Can't Shake0:44:52 How "Lunch" Is Three Contradictory Things at Once0:57:47 Does Meaning Have a Mathematical Shape?1:03:34 Is Grammar Invented — or Discovered in a Platonic Space?1:13:54 What Even Is Agency?1:25:00 What Actually Separates You From an AI1:30:12 Where to Start With Nietzsche and Dostoevsky... Email for sponsorship enquiries: [email protected] Episodes MentionedMichael Levin — Michael Levin: Bioelectricity, Morphogenesis, Platonic Spaces & Xenobots: https://www.youtube.com/watch?v=LTBZRVKUwyMMichael Levin & Earl Miller — Meet the Scientist Showing Every Cell In Your Body is Conscious!: https://www.youtube.com/watch?v=eNi-_2cOVtcGuest LinksElliot Murphy — Website: https://elliot-murphy.comElliot Murphy — Google Scholar: https://scholar.google.co.uk/citations?user=4AYNRj0AAAAJElliot Murphy — UTHealth Profile: https://www.uth.edu/people/profile?id=a676259c-6b83-45de-bba3-f9ce464344a6
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  #140 - Meet The DMT Explorer Who's Had 100+ Encounters With Non Human Entities 23.07.2026 2ч 4мин

  Try Mind Lab Pro, The Universal Nootropic For A Sharper Brain: https://www.mindlabpro.com/?a_aid=67fd1cb8d9ad3&a_bid=6d45f5c3Want a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/aboutAdam Butler is a DMT researcher and author who has taken the molecule over 100 times and completed the same Monroe Institute consciousness program the CIA funded during the Cold War. He went from suicidal alcoholic to sober and mission-driven through a molecule his own brain already produces -- and then, one day, found himself completely locked out of the DMT space with zero pharmacological explanation for why.Expect to learn why DMT stops working for some people with no pharmacological explanation for it, how the body produces its own DMT internally, what the Monroe Institute's Hemi-Sync binaural beats protocol has in common with a DMT trip without any substance at all, why a declassified CIA-linked report took remote viewing seriously enough to fund it for decades, what DMT entities actually look like across 100+ trips, the controversial DMT laser experiment that claims to reveal a rigid code-like grid in the visual field, why effect sizes in psychedelic-assisted therapy trials are becoming impossible to ignore, and much more…Timestamps0:00:00 Trailer0:02:17 Who Is Adam Butler? From Rock Bottom to a Mission0:07:18 The Story That Changed Everything0:13:21 Inside His First DMT Session0:24:22 Why DMT Doesn't Build Tolerance0:31:56 Blocked: The Night DMT Just Stopped Working0:38:22 The Telepathy Tapes and the DMT Laser Experiment0:40:38 Huxley's Reducing Valve and the DMT "Cheat Code"0:44:29 What Is a DMT Entity, Really?0:48:21 Jesters, Mantis Beings, and the Entity Portfolio0:54:48 Carhart-Harris's Theory vs Alien World-Building1:02:52 Do DMT Entities Have Their Own Agency?1:09:20 The Mantis "Technicians" and the Body Upgrade1:11:23 Meeting His Future Self on DMT1:17:28 Inside the Monroe Institute1:32:17 The Declassified CIA Gateway Project1:41:10 Temporal Lobe Epilepsy and DMT-Like States1:44:27 The DMT Laser Experiment Explained1:53:21 Debating the "Code of the Simulation" Claim1:58:37 Near-Death Experience and Why It All Matters... Email for sponsorship enquiries: [email protected] Episodes Mentioned:Robin Carhart-Harris — No. 1 Psychedelic Scientist: The Entropic Brain Hypothesis, Consciousness & DMT Entities: https://youtu.be/t-GkE4YtLRkAndrew Gallimore — No.1 DMT Neurobiologist: Alien Worlds, DMT Entity Encounters, Attractor States and Consciousness: https://www.youtube.com/watch?v=USgWrxEFWDAAndrés Gómez Emilsson — Consciousness Expert Explains The 6 Levels Of The DMT Experience: https://youtu.be/xMdl7zF2MWEGuest Links:Instagram: https://www.instagram.com/booksbyadambutlerYouTube: https://www.youtube.com/@ButlersDMTFieldGuidePatreon: https://www.patreon.com/BooksByAdamButlerBook — Butler's DMT Field Guide: https://www.amazon.com/dp/196050505XBook — Butler's Psychedelic Integration Field Guide: https://www.amazon.com/dp/B0H4GL8H6V...Email for sponsorship enquiries: [email protected]
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  #139 - Meet The Greatest Ibogaine Psychedelic Scientist You’ve Never Heard Of 20.07.2026 1ч 42мин

  Download the most scientifically rigorous nutrition app MacroFactor! Use code GIANTS for a 2 week FREE trial: https://onelink.to/giantsGet Manta Sleep Mask: https://bit.ly/4ilzfBL and Code GIANTSMANTA10Want a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/aboutDalibor Sames is the chemist who reverse-engineered ibogaine into a version that appears to erase heroin addiction in a single dose, without the cardiac risk that can kill people on the original drug. He also took his own medicine — and says he watched the molecule's exact 3D structure rotate in front of him for 36 hours straight.Expect to learn why ibogaine breaks every rule of classical pharmacology, what "matrix pharmacology" means and why it's heresy to a one-drug-one-target industry, how editing a single atom deletes ibogaine's fatal heart risk, why a common antidepressant turned out to be a secret opioid for thirty years, what it's like to watch a molecule's structure appear during a 36-hour flood dose, why ibogaine seems to erase interest in alcohol overnight, whether the "DMT block" phenomenon researchers describe is real, and much more…Timestamps0:00:00 Trailer0:02:39 Meet the Chemist Who Fell for a Molecule's Shape0:04:13 The Dogma That the Adult Brain Can't Heal0:09:00 Why Synapses Might Explain Every Brain Disorder0:10:28 Reverse-Engineering Nature's Own Drugs0:16:44 The Paper That Changed Everything About Addiction0:20:01 Why Ibogaine Breaks Every Rule of Pharmacology0:33:08 The Weakest Drug That Works the Strongest0:38:21 The Traffic Jam That Explains Matrix Pharmacology0:44:18 A Human Genome Project — For One Molecule0:47:48 Deciding to Take Ibogaine Himself0:50:02 Inside a 36-Hour Flood Dose0:54:38 The Chapter Called "Treatment"0:56:26 Ibogaine Shows Him the Future of Design1:00:01 Seeing Ibogaine's 3D Molecular Structure1:03:14 High-Fiving a Molecule1:06:47 "This Is a Computational Technology"1:16:36 The Simulation So Real It Panicked Him1:24:26 Did He Earn This Experience?1:30:56 Six Months Later — What Actually Changed1:36:01 Did This Change His View of Consciousness?...... Email for sponsorship enquiries: [email protected] Episodes MentionedAndrew Gallimore — No.1 DMT Neurobiologist: Alien Worlds, DMT Entity Encounters, Attractor States and Consciousness: https://www.youtube.com/watch?v=USgWrxEFWDADavid Luke — Meet the Professor of Paranormal Consciousness - DMT Entities, Telepathy Tapes & OBE's: https://www.youtube.com/watch?v=qLKD1gt1X5oGuest LinksColumbia Chemistry faculty page: https://www.chem.columbia.edu/content/dalibor-samesSames Lab: https://www.samesgroup.org/professor-dalibor-samesGilgamesh Pharmaceuticals: https://www.gilgameshpharmaceutical.com/Oxa-Iboga paper (Nature Communications, 2024): https://doi.org/10.1038/s41467-024-51856-yBeond Ibogaine Clinic (where he took ibogaine): https://beondibogaine.com
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  #138 - Meet The Greatest Ayahuasca Psychedelic Scientist You’ve Never Heard Of. 17.07.2026 1ч 14мин

  Download the most scientifically rigorous nutrition app MacroFactor! Use code GIANTS for a 2 week FREE trial: https://onelink.to/giantsWant a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/aboutDráulio Barros de Araújo is a physicist who spent twenty years pointing MRI scanners at the ayahuasca experience, and ran the world's first controlled trial proving a single dose of a psychedelic could lift treatment-resistant depression in a week. He thinks DMT entity encounters are not hallucinations, and he wants to know if they could be real.Expect to learn why calling ayahuasca visions "hallucinations" is scientifically wrong, why you can't overdose or build tolerance to ayahuasca the way you can with alcohol or cocaine, why vomiting is considered part of the medicine rather than a side effect, how a physicist measured the entropy of a mystical experience and watched it rise, why your eyes physically won't stay open during a vision, the hippocampal memory glitch that may explain why DMT entities feel real, and why psychedelic science may be measuring altered states with the wrong tools entirely.Timestamps0:00:00 Trailer0:02:50 Who Is the Physicist Studying Ayahuasca Visions0:05:05 The 1930s Origin of Brazil's Ayahuasca Churches0:10:13 Why You Can't Buy Ayahuasca Like a Coca-Cola0:11:22 What a Typical Ayahuasca Trip Actually Feels Like0:16:53 Why LSD Visions Happen With Eyes Open, Ayahuasca Doesn't0:17:22 Your Brain on Ayahuasca Looks Like a Dream, Not a Hallucination0:21:08 Why Ayahuasca Visions Never Feel Like "Just a Dream"0:22:23 There's No Such Thing as an Ayahuasca Overdose0:24:18 Why Vomiting and Diarrhea Are Part of the Medicine0:28:34 The Hippocampus Theory of Why DMT Entities Feel Real0:33:22 Would Irish People See Snakes on Ayahuasca Too?0:35:40 We're Measuring Trips With the Wrong Scientific Tools0:40:44 Speech Analysis: A New Way to Study the Trip0:44:31 The Flawed Questionnaire Behind Every Psychedelic Study0:50:23 Why Dráulio Refuses to Ask a Single Direct Question0:55:19 The Entropic Brain Hypothesis, Explained by a Physicist1:02:01 Why Psychedelics Dissolve Your Career Ambitions1:04:02 The Most Important Psychedelic Question Science Avoids: Death1:06:09 What the West Should Learn From Indigenous Ayahuasca Traditions... Email for sponsorship enquiries: [email protected] Episodes MentionedDavid Luke — Meet the Professor of Paranormal Consciousness - DMT Entities, Telepathy Tapes & OBE's: https://www.youtube.com/watch?v=qLKD1gt1X5oRobin Carhart-Harris — No. 1 Psychedelic Scientist: The Entropic Brain Hypothesis, Consciousness & DMT Entities: https://www.youtube.com/watch?v=t-GkE4YtLRkDavid Nutt — Neuroscientist Ranks Every Drug By How Hard They Are to Quit! Tier List Part 2: https://www.youtube.com/watch?v=CEgbv6IHYaYGuest LinksUFRN Brain Institute — Faculty Profile: https://neuro.ufrn.br/institute/members/investigators/draulioGoogle Scholar: https://scholar.google.com/citations?user=NoO4Rt0AAAAJCentro Avançado de Medicina Psicodélica (CAMP): https://www.camp-sci.com/ptLinkedIn: https://www.linkedin.com/in/draulio-araujo-06ab47125
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  #137 - Dennis McKenna: "I've Spent 50 Years Investigating The Entities That Exist Within Ayahuasca" 13.07.2026 1ч 31мин

  Get Manta Sleep Mask: https://bit.ly/4ilzfBL and Code GIANTSMANTA10Want a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/aboutDennis McKenna is an ethnopharmacologist who spent fifty years decoding the chemistry of psychedelic plants, producing the first hard pharmacological proof of why ayahuasca actually works. He's also the younger brother of Terence McKenna, and in 1971 the two of them ran an experiment on their own minds in the Colombian Amazon that ended in a two-week psychotic break neither has ever fully explained.Expect to learn why the McKenna brothers thought DMT was a portal to another dimension rather than a drug trip, what happened during Dennis's two-week dissociation from reality in the Amazon, how ayahuasca's DMT and MAO-inhibitor plants actually work together in the body, why Dennis still calls the entire 1971 expedition "an act of science fiction, not science," how his PhD research became the first pharmacological proof of why ayahuasca works, why he thinks his own brother unintentionally seeded the "machine elf" into everyone else's DMT trips, why a career pharmacologist has never personally seen one himself, and why DMT entity encounters may be linked to real mental health outcomes, and much more…Timestamps0:00:00 Trailer0:03:07 How Dennis Got Into Psychedelics0:06:07 Terence The Philosopher vs Dennis The Scientist0:11:11 The 1971 Expedition To The Colombian Amazon0:16:05 Why DMT Was "The Holy Grail"0:17:50 The Ayahuasca Chemistry Nobody Understood Yet0:18:45 Hunting For The Legendary Oo-Koo-Hé0:22:00 Stumbling Into A Mushroom Paradise0:27:05 When The Mushrooms Started "Talking"0:28:38 The DNA Resonance Experiment0:36:01 The Two-Week Psychotic Break0:40:46 Psychotic Break, Shamanic Initiation, Or Alien Encounter?0:47:08 From Psychotic Break Back To The Lab0:53:16 Proving How Ayahuasca Actually Works0:58:47 The Book That Seeded Mushrooms Into Society1:05:39 Sasha Shulgin And The Chemistry Of Psychedelics1:11:02 "I've Never Seen A Machine Elf Myself"1:17:56 Pushing The DMT Experience To Five Hours1:20:02 What Makes DMT Different From Psilocybin1:26:18 DMT Entities And Mental Health Outcomes...... Email for sponsorship enquiries: [email protected] MentionedAndrew Gallimore — No.1 DMT Neurobiologist: Alien Worlds, DMT Entity Encounters, Attractor States and Consciousness: https://www.youtube.com/watch?v=USgWrxEFWDADavid Luke — Meet the Professor of Paranormal Consciousness - DMT Entities, Telepathy Tapes & OBE's: https://www.youtube.com/watch?v=qLKD1gt1X5oGuest LinksHeffter Research Institute Bio: https://www.heffter.org/dennis-j-mckenna-phd/McKenna Academy of Natural Philosophy: https://mckenna.academy/mka-team/dennis-mckenna/X: https://x.com/DennisMcKenna4Book — The Brotherhood of the Screaming Abyss: http://brotherhoodofthescreamingabyss.com/ResearchGate: https://www.researchgate.net/profile/Dennis-Mckenna
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  #136 - Denis Noble: Neo-Darwinism, Michael Levin & Why The Last 70 Years of Genetics Is Wrong 10.07.2026 1ч 30мин

  Get Jenni Your Intelligent Research Assistant (GIANT20 for 20% off) - http://jenni.ai/utm_source=youtube&utm_medium=inf&utm_campaign=thegiantsshoulderGet Manta Sleep Mask: https://bit.ly/4ilzfBL and Code GIANTSMANTA10Denis Noble is the physiologist who built the first computer model of the heart in 1960 — and has spent the sixty years since using it to dismantle the gene-centric view of life that dominates modern biology. He took Richard Dawkins's Selfish Gene and rewrote its most famous passage word for word in reverse — and every single experiment still fits.Expect to learn why the central dogma of molecular biology is provably wrong, how your immune system rewrites its own DNA to fight off new viruses, why the peppered moth story in every biology textbook turns out to be false, what happened when Denis told Richard Dawkins "Lamarck is back" to his face, why a cell corrects roughly 800,000 DNA replication errors before it's allowed to divide, how epigenetic inheritance can persist indefinitely if the environment stays changed, whether plants might have a form of experience, and where exactly agency ends and pure chemistry begins.Timestamps0:00:00 Trailer0:02:27 Meet The Man Who Modeled The Heart By Hand0:04:43 Why The Central Dogma Of Biology Is Wrong0:06:39 The 1866 Split Between Darwin And Wallace0:09:02 The Infinite Monkey Theorem, Tested For Real0:17:30 The Peppered Moth Myth Textbooks Still Teach0:20:19 The Nobel Laureate Textbooks Forgot To Cite0:22:53 Telling Richard Dawkins "Lamarck Is Back"0:27:43 Was Lamarck's Giraffe Neck Story Actually Right?0:29:40 How Your Body Talks To Your DNA0:38:17 A New Species Evolved In Two Generations0:44:18 So What's Actually Controversial Here?0:48:09 Cellular Agency: When Cells Act Like Organisms0:53:04 Steelmanning The Case Against Cellular Agency0:55:05 The 17th-Century Prediction That Proved Purpose Works1:04:20 Your Cells Correct 800,000 DNA Errors Per Division1:13:14 Life Lives On The Edge Of Order And Chaos1:15:27 Do Plants Have Experience?1:27:31 How Does Consciousness Fit Into Systems Biology?...... Email for sponsorship enquiries: [email protected] Episodes MentionedMichael Levin — Meet the Scientist Creating New Forms of Synthetic Life! Dr Michael Levin: https://www.youtube.com/watch?v=LTBZRVKUwyMPhilip Ball — Philip Ball: "Biology Is Infinitely Weirder Than We Thought": https://www.youtube.com/watch?v=9SseGx0R0fYGuest LinksOxford Faculty Page: https://www.dpag.ox.ac.uk/team/denis-noblePersonal Website: https://www.denisnoble.comGoogle Scholar: https://scholar.google.com/citations?user=J6kLmsIAAAAJ&hl=enUnderstanding Living Systems (Book): https://www.amazon.com/Understanding-Living-Systems-Life/dp/1009277367The Third Way of Evolution: https://www.thethirdwayofevolution.com/people/view/denis-noble