Ophthalmology Journal

Goniotomy Outcomes in the IRIS Registry 02.07.2026 16min

Dr. Emily Schehlein interviews Dr. Julia H. Joo and Dr. Ang Li on their study which used the IRIS® Registry to investigate the predictive factors for goniotomy success. From their Ophthalmology Glaucoma article, "Factors Associated with Goniotomy Outcomes in the United States." Factors Associated with Goniotomy Outcomes in the United States. Joo J, et al. Ophthalmology Glaucoma. 2026. In press.

A New Visual Field for Hydroxychloroquine Screening 18.06.2026 20min

Dr. Rajesh Rao interviews Dr. Michael Marmor on his recent Ophthalmology Retina editorial, A New Visual Field for Hydroxychloroquine Screening, and discuss the performance of the Humphrey 24-2C visual field test for detecting parafoveal and pericentral hydroxychloroquine retinopathy. A New Visual Field for Hydroxychloroquine Screening. Marmor M. Ophthalmology Retina, Volume 10, Issue 3, 221-222.

Systemic Workup in Isolated Paracentral Acute Middle Maculopathy 04.06.2026 18min

Dr. Drew Carey interviews Dr. Avner Hostovsky on his study evaluating the diagnostic yield of a structured systemic workup in patients presenting with acute visual symptoms who were diagnosed with isolated paracentral acute middle maculopathy (PAMM). From his Ophthalmology article, "High Yield of Systemic Workup in Patients with Acute Isolated Paracentral Acute Middle Maculopathy." Hostovsky A, Peled I, Katz G, et al. High Yield of Systemic Workup in Patients with Acute Isolated Paracentral Acute Middle Maculopathy. Ophthalmology, 2025; 133, 499-505.

Detecting Inflammation in Fundus Photos Using Machine Learning 21.05.2026 22min

Dr. Drew Carey is joined by Drs. S. Saeed Mohammadi and Quan Dong Nguyen, authors of Ophthalmology Science's "Detecting Inflammation in Fundus Photographs Using Machine Learning." They discuss their study investigating the use of AI in the diagnosis of uveitis from ultra-widefield fundus photographs. Detecting Inflammation in Fundus Photographs Using Machine Learning. Mohammadi S, Yavari N, Saengsirinavin A, et al. Ophthalmology Science, Volume 6, Issue 2.

Hydrus Microstent Clinical Outcomes for Open-Angle Glaucoma 07.05.2026 17min

Dr. Thomas Johnson returns to the podcast. Dr. Emily Schehlein interviews him on his study to assess the clinical outcomes of Hydrus Microstent implantation with cataract extraction for the treatment of open-angle glaucoma. From the Ophthalmology Glaucoma article, Clinical Outcomes of Hydrus Microstent Implantation for Open-Angle Glaucoma: Results from a Large Academic Center. Clinical Outcomes of Hydrus Microstent Implantation for Open-Angle Glaucoma. Hamilton, Natalie R. et al. Ophthalmology Glaucoma, Volume 9, Issue 1, 48 - 61

ChatGPT-4o Responses to Patient Questions 23.04.2026 18min

How accurate is ChatGPT responding to patient questions at a 6th grade reading level vs. a 12th grade reading level? Find out in this episode as Drs. Rukhsana Mirza and Angelo Tanna discuss their Ophthalmology Science article, "Accuracy and Readability of Chat Generative Pre-Trained Transformer-4 Omni in Answering Ophthalmology Patient Questions." Accuracy and Readability of Chat Generative Pre-Trained Transformer-4 Omni in Answering Ophthalmology Patient Questions. Hamzeh, Nikoo et al. Ophthalmology Science, Volume 6, Issue 2. Looking for ways to give back? By becoming an EyeCare America volunteer, you could help provide eye care to those in your community most in need, from the comfort of your own office. EyeCare America, established by the American Academy of Ophthalmology in 1985 as the first public service program for eye care, connects uninsured and underinsured patients 18 and over in need of medical eye exams with local ophthalmologists. Visit eyecareamerica.org for more info.

Autofluorescence in Retinal Detachments 09.04.2026 18min

Dr. Rukhsana Mirza sits down with Dr. Avni P. Finn to discuss her Ophthalmology Science article, "Ultra-Widefield Fundus Autofluorescence Findings as an Indicator of Duration in Rhegmatogenous Retinal Detachment," which used ultra-widefield color fundus photography and fundus autofluorescence to assess patients with rhegmatogenous retinal detachment, relating clinical features to imaging findings and comparing between the 2 imaging modalities. Ultra-Widefield Fundus Autofluorescence Findings as an Indicator of Duration in Rhegmatogenous Retinal Detachment. Zhang, David L. et al. Ophthalmology Science, Volume 6, Issue 2. Working on new research? Researchers around the world are already submitting abstracts for AAO 2026. If you're preparing a paper, poster, or video, now is the time to share it. Abstract submissions close April 14. Submit your abstract today. Visit aao.org/pod26.

Rate and Rationale for Vitrectomy after Pneumatic Retinopexy 26.03.2026 25min

Dr. Rajesh Rao interviews Dr. Bradley T. Smith on his study to report the rate and rationale for vitrectomy after retinal detachment repair with pneumatic retinopexy, from his Ophthalmology Retina article, "Rate and Rationale for Vitrectomy after Pneumatic Retinopexy." Rate and Rationale for Vitrectomy after Pneumatic Retinopexy. Smith, Bradley T. et al. Ophthalmology Retina, Volume 9, Issue 11, 1053 – 1061. Looking for ways to give back? By becoming an EyeCare America volunteer, you could help provide eye care to those in your community most in need, from the comfort of your own office. EyeCare America, established by the American Academy of Ophthalmology in 1985 as the first public service program for eye care, connects uninsured and underinsured patients 18 and over in need of medical eye exams with local ophthalmologists. Visit eyecareamerica.org for more info.

Using AI LLMs For Extracting Eye Exam Findings from EHR Notes 12.03.2026 20min

With the current AI boom, physicians are looking for ways to use this new technology in their practices. Dr. Edmund Tsui interviews Dr. Sophia Y. Wang on her Ophthalmology Science article, "Leveraging Large Language Models with Sequential Prompting to Extract Eye Examination Findings from Free-Text Ophthalmology Notes," which showed that LLMs are capable of efficient, automated, and accurate extraction of relevant information from ophthalmology free-text progress notes. Leveraging Large Language Models with Sequential Prompting to Extract Eye Examination Findings from Free-Text Ophthalmology Notes. Ruan, Franklin Y. et al. Ophthalmology Science, Volume 6, Issue 1. If you're working on research right now, consider sharing your latest research at AAO 2026. Abstract submissions for papers, posters, and videos are open now, through April 14. It's a great opportunity to present your work — and connect with colleagues from around the world. Start your submission today at aao.org/pod26.

Ophthalmology Transfers to an Academic Trauma Center 26.02.2026 24min

Dr. Edmund Tsui is joined by Dr. Shu Feng, author of Ophthalmology's Assessing the Efficacy of Ophthalmic Transfers to an Academic Level 1 Trauma Hospital, to discuss her study of ophthalmic transfers to an academic level 1 trauma center and the accuracy of transferring diagnoses and rate of intervention after transfer. Assessing the Efficacy of Ophthalmic Transfers to an Academic Level 1 Trauma Hospital. Hopkin, Blake et al. Ophthalmology, Volume 133, Issue 1, 24 – 30.

American Glaucoma Society's 40th Anniversary 12.02.2026 40min

We're celebrating the American Glaucoma Society's 40th Anniversary! Dr. Emily Schehlein interviews three glaucoma luminaries, previous AGS Presidents, and guest editors for Ophthalmology Glaucoma's AGS 40th Anniversary special issue: Dr. Steven Gedde, Dr. Carla Siegfried, and Dr. Greg Skuta. Together they discuss the past, present, and future of the AGS, advancements in the treatment of glaucoma, and share their personal stories of mentorship and community within the society. Read Ophthalmology Glaucoma's American Glaucoma Society 40th Anniversary supplement issue here: https://www.ophthalmologyglaucoma.org/issue/S2589-4196(25)X0006-5 To find out more about the AGS, how to join, and get involved visit: https://www.americanglaucomasociety.net/home Sign up for the next Ophthalmology Journal Virtual Club on February 25, 2026, at https://store.aao.org/ophthalmology-virtual-journal-club.html

GLP-1RA Use and Risk of Neovascular AMD 29.01.2026 25min

It's our 100th episode! Dr. Rukhsana Mirza sits down with Drs. Aleksandra V. Rachitskaya and Kevin C. Allan to discuss their retrospective study using the TriNetX network to investigate the risk of neovascular age-related macular degeneration (AMD) in patients taking glucagon-like peptide-1 receptor agonists (GLP-1RAs). From their Ophthalmology Retina article, "Glucagon-Like Peptide-1 Receptor Agonist Use and Risk of Neovascular Age-Related Macular Degeneration in a National Cohort Study." Glucagon-Like Peptide-1 Receptor Agonist Use and Risk of Neovascular Age-Related Macular Degeneration in a National Cohort Study. Allan, Kevin C. et al. Ophthalmology Retina. In press Sign up for the next Ophthalmology Journal Virtual Club on February 25, 2026, at https://store.aao.org/ophthalmology-virtual-journal-club.html

Adalimumab vs. Conventional Immunosuppression for Uveitis 15.01.2026 17min

Dr. Edmund Tsui and author Dr. Douglas A. Jabs discuss the results of the ADVISE Trial, designed to compare adalimumab to conventional immunosuppressive drugs for the treatment of non-infectious intermediate, posterior, and panuveitides. From Dr. Jab's Ophthalmology article, "Adalimumab vs. Conventional Immunosuppression for Uveitis (ADVISE) Trial." Adalimumab vs. Conventional Immunosuppression for Uveitis (ADVISE) Trial. Jabs, Douglas A. et al. Ophthalmology. In press. Sign up for the next Ophthalmology Journal Virtual Club on February 25, 2026, at https://store.aao.org/ophthalmology-virtual-journal-club.html

Age-Related Macular Degeneration and the Gut Microbiome 18.12.2025 21min

Our newest host and Social Media Editor, Dr. Rukhsana Mirza, interviews Dr. Phoebe Lin. Together, they discuss Dr. Lin's study on whether an intestinal microbial signature is associated with advanced age-related macular degeneration and the relationship between the microbiota and AMD genetic risk. From her Ophthalmology Science article, "Age-related Eye Disease Studies Supplements and Genetic Risk Score Are Crucial Determinants of Intestinal Microbial Alterations in Advanced Age-Related Macular Degeneration." Dr. Phoebe Lin is an editor for Ophthalmology Science. Age-related Eye Disease Studies Supplements and Genetic Risk Score Are Crucial Determinants of Intestinal Microbial Alterations in Advanced Age-Related Macular Degeneration, Dadgar, Neda et al. Ophthalmology Science, Volume 6, Issue 1.

Elevated Intraocular Pressure after Cataract Surgery and Risk of Glaucoma 04.12.2025 15min

Dr. Emily Schehlein is joined by Dr. Cecilia S. Lee and Dr Parisa Taravati, authors of "Elevated Intraocular Pressure Immediately after Cataract Surgery and Future Risk of Primary Open-Angle Glaucoma in the IRIS® Registry (Intelligent Research in Sight)." Together they discuss the associations between postoperative intraocular pressure after cataract surgery and the future risk of developing primary open-angle glaucoma in patients without prior glaucoma, glaucoma suspect, or ocular hypertension diagnoses. Elevated Intraocular Pressure Immediately after Cataract Surgery and Future Risk of Primary Open-Angle Glaucoma in the IRIS® Registry (Intelligent Research in Sight). Gim, Nayoon et al. Ophthalmology Science, Volume 5, Issue 6.

Outpatient Oral Doxycycline vs. IV Penicillin for Syphilitic Uveitis 20.11.2025 18min

Dr. Edmund Tsui interviews Dr. Brian C. Toy on his retrospective cohort study which shows that oral doxycycline clinical and serologic outcomes are comparable to IV penicillin for syphilitic uveitis, published in Ophthalmology. From "Outpatient Oral Doxycycline versus Intravenous Penicillin for Syphilitic Uveitis." Outpatient Oral Doxycycline versus Intravenous Penicillin for Syphilitic Uveitis. Bao, Yicheng K. et al. Ophthalmology, Volume 132, Issue 12, 1457 - 1459.

The CorNeat Everpatch and the Process of FDA Authorization 06.11.2025 29min

On September 5, 2025, the FDA issued a recall for the CorNeat EverPatch. Dr. Emily Schehlein is joined by Dr. Thomas V. Johnson to discuss his study on the early exposure and surgical revision rates of the CorNeat EverPatch. Later, Dr. Henry Jampel explains the difference between FDA clearance and FDA approval for medical devices. Dr. Johnson coauthored the Ophthalmology article, "Early Postoperative Conjunctival Complications Leading to Exposure of Surgically Implanted CorNeat EverPatch Devices." Dr. Jampel cowrite the accompanying Commentary, "The CorNeat Everpatch and the Process of FDA Authorization." Dr. Henry Jampel is an Associate Editor for Ophthalmology and the Editor-in-Chief for Ophthalmology Glaucoma. Dr. Thomas V. Johnson is an Associate Editor for Ophthalmology Science. Early Postoperative Conjunctival Complications Leading to Exposure of Surgically Implanted CorNeat EverPatch Devices. Kanter, Jacob et al. Ophthalmology, Volume 132, Issue 7, 799 – 814. The CorNeat Everpatch and the Process of FDA Authorization. Jampel, Risa; Jampel, Henry. Ophthalmology, Volume 132, Issue 7, 815 – 816. The Academy's BCSC is your trusted source of clinical knowledge. The 2025-2026 edition includes a major revision to Section 8: External Disease and Cornea. Updates include a new interactive case study on Fuchs endothelial corneal dystrophy and cataracts, as well as 15 new videos of surgical procedures. Advance order Section 8 today at aao.org/BCSC.

Direct Selective Laser Trabeculoplasty in Open-Angle Glaucoma 23.10.2025 23min

Dr. Emily Schehlein sits down with author Dr. Nathan Congdon to break down the results of the GLAUrious Study on comparing automated, gonioscopy-free, noncontact, image-guided direct selective laser trabeculoplasty with conventional SLT in open-angle glaucoma and ocular hypertension to reduce intraocular pressure. From the Ophthalmology article, "Randomized Noninferiority Trial of Direct Selective Laser Trabeculoplasty in Open-Angle Glaucoma and Ocular Hypertension." Randomized Noninferiority Trial of Direct Selective Laser Trabeculoplasty in Open-Angle Glaucoma and Ocular Hypertension. Gazzard, Gus; Traverso, Carlo Enrico; et al. Ophthalmology, Volume 132, Issue 10, 1091 – 1104.

Epiretinal Membrane in Diabetic Patients 09.10.2025 11min

Dr. Rajesh Rao discusses the risk factors for epiretinal membrane formation in patients with diabetes mellitus with Dr. Shinji Kakihara, first author of the Ophthalmology Science article, "Epiretinal Membrane Is Associated with Diabetic Retinopathy Severity and Cumulative Anti-VEGF Injections." Epiretinal Membrane Is Associated with Diabetic Retinopathy Severity and Cumulative Anti-VEGF Injections. Kakihara, Shinji et al. Ophthalmology Science, Volume 5, Issue 3. If you are unable to travel to AAO 2025, you can still enjoy the unparalleled program by registering for AAO 2025 Virtual. Get access to the annual meeting course and sessions recorded in Orlando, on-demand-only content specifically for the online platform, videos and posters, and CME credits. Learn more and register at aao.org/RegNow. Ophthalmology journal events at AAO 2025: · Peer Review Masterclass: A Practical Workshop for Journal Authors and Reviewers: Become a peer reviewer for the Academy's Ophthalmology journal, the leading journal in the field, and its companion journals, Ophthalmology Retina, Ophthalmology Glaucoma, and Ophthalmology Science. Dr. Emily Schehlein and Dr. Aaki Shukla, highly experienced reviewers and authors for various journals, will lead this free interactive workshop. Sponsored by Elsevier. · The Year in Literature: Editor's Choice Highlights From the Ophthalmology Journal Family: Join Ophthalmology's Editor-in-Chief, Dr. Russell Van Gelder, as he presents the top Ophthalmology articles on Sunday October 19 at 9:45am. Search "SYM31" in the Mobile Meeting Guide for more information. · Meet the Editor: Join us for an intimate conversation with Ophthalmology Editor-in-Chief, Dr. Russ Van Gelder, during the American Academy of Ophthalmology Annual Meeting. This special meet and greet offers ophthalmologists, residents, and researchers a unique chance to connect directly with one of our field's most influential editorial voices. Sunday, October 19, 3:30-4:30 pm, Academy Hub at the exhibit hall.

Pediatric Noninfectious Uveitis in the US 25.09.2025 27min

Dr. Edmund Tsui sits down with Drs. Akshay S. Thomas and Ogul E. Uner to discuss their IRIS Registry study of the prevalence, characteristics, and treatment patterns of pediatric noninfectious uveitis in the United States. From their Ophthalmology Retina article, "Prevalence, Treatment Patterns, and Outcomes of Pediatric Noninfectious Uveitis in the United States: An IRIS Registry Analysis" Prevalence, Treatment Patterns, and Outcomes of Pediatric Noninfectious Uveitis in the United States: An IRIS Registry Analysis. Uner, Ogul E. et al. Ophthalmology Retina. In press. You love learning, which is why you listen to this podcast. Get live pearls and even more insights from top speakers from around the world at AAO 2025, the largest ophthalmology meeting in the world! Register now and get ready for Orlando at aao.org/RegNow. Ophthalmology journal events at AAO 2025: Peer Review Masterclass: A Practical Workshop for Journal Authors and Reviewers: Become a peer reviewer for the Academy's Ophthalmology journal, the leading journal in the field, and its companion journals, Ophthalmology Retina, Ophthalmology Glaucoma, and Ophthalmology Science. Dr. Emily Schehlein and Dr. Aaki Shukla, highly experienced reviewers and authors for various journals, will lead this free interactive workshop. Sponsored by Elsevier. The Year in Literature: Editor's Choice Highlights From the Ophthalmology Journal Family: Join Ophthalmology's Editor-in-Chief, Dr. Russell Van Gelder, as he presents the top Ophthalmology articles on Sunday October 19 at 9:45am. Search "SYM31" in the Mobile Meeting Guide for more information. Meet the Editor: Join us for an intimate conversation with Ophthalmology Editor-in-Chief, Dr. Russ Van Gelder, during the American Academy of Ophthalmology Annual Meeting. This special meet and greet offers ophthalmologists, residents, and researchers a unique chance to connect directly with one of our field's most influential editorial voices. Sunday, October 19, 3:30-4:30 pm, Academy Hub at the exhibit hall.