The Neuro Experience
Louisa Nicola & Pursuit Network
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This podcast interviews the best experts in the world to bring emerging themes in athletic performance, neurology, sleep physiology and medicine. Louisa regularly consults for technology development companies, professional athletic organizations and consults with the biggest names in NBA, MLB and NFL. Louisa is on the scientific advisory board of Tonal, Hone Health, Klora and Momentous. Find Louisa on Instagram @louisanicola_
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If You Want To Build Muscle FAST You Need To Start Doing THIS! | Brad Schoenfeld 02.06.2026 1sa 13dkIf you think you need to train to failure to build muscle, you've been operating on outdated science. Dr. Brad Schoenfeld has nearly 400 peer-reviewed papers on hypertrophy and he's done a complete 180 on some of his most firmly held beliefs. In this episode, I sit down with Dr. Brad Schoenfeld, PhD, professor of exercise science and one of the world's most cited researchers in muscle hypertrophy. We break down the training myths that are still circulating online including why training to failure isn't necessary, why light weights can build as much muscle as heavy ones, and why two 30-minute sessions a week is genuinely enough for most people. Brad also explains the science of type one versus type two fiber loss with age, how GLP-1s are complicating muscle retention, and what the research actually says about rest intervals, cold plunges, and post-exercise heat. We also go deep into the cutting edge of hypertrophy science: lengthened partials, electro-stimulation, the overlooked connection between muscle and metabolic health, and the key additions in the third edition of his landmark textbook. This episode is for anyone who trains, wants to train, or wants to understand what science actually says about building a body that performs and lasts. Reduce your risk of Alzheimer's with my science-backed protocol for women 30+: https://go.neuroathletics.com.au/youtube-sales-page Subscribe to The Neuro Experience for evidence-based conversations at the intersection of brain science, longevity, and performance. _____ TOPICS DISCUSSED 00:00 Intro: The Belief Brad Held in the 90s That Science Has Since Overturned 01:08 Meet Dr. Brad Schoenfeld: 400 Papers and What We Still Don't Know About Muscle Growth 06:13 Light Weights vs. Heavy Weights: The Study That Changed Everything 09:10 Type I vs. Type II Muscle Fibers and Why Type II Atrophies With Age 11:43 Muscle, Brain Health, and the Two-Days-a-Week Resistance Training Protocol 17:26 Strength vs. Power: Why Explosive Training Matters More Than You Think 21:32 The Biggest Lie in Fitness: There Is No Single Best Way to Build Muscle 23:15 Two 30-Minute Sessions a Week Is Enough 27:01 Protein Requirements for Muscle Growth: Where the Research Actually Lands 31:18 GLP-1s and Muscle Loss: What the Evidence Says 38:36 Aerobic Training, Step Count, and Where Cardio Fits In 40:47 How Muscle Improves Every Organ System in Your Body 44:35 Research Gaps in Advanced Training Techniques 49:00 Mechanical Tension as the Primary Driver of Hypertrophy 53:37 Rest Intervals: How Long You Actually Need Between Sets 58:20 Lengthened Partials: The Training Insight That Surprised the Field 01:02:10 Electrostimulation and At-Home Resistance Technology: Does It Work? 01:05:41 Cold Plunges After Lifting: Why Brad Says Avoid Them 01:07:52 Sleep and Muscle Building: What the Evidence Does and Doesn't Show 01:11:30 The Third Edition: Evidence-Based Practice and How to Use Research _______ Thank you to our sponsors KetoneIQ: https://ketone.com/NEURO for 30% OFF Function Health: https://www.functionhealth.com/louisanicola IQBARS: https://www.eatiqbar.com/ Biologica: https://biologica.com/NEURO Up to 32% off first subscription order _______ I’m Louisa Nicola - clinical neurophysiologist - Alzheimer’s prevention specialist - founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain- reducing Alzheimer’s risk and staying mentally sharp for life, you’re in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices
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Exercise Expert: The FASTEST Way to Lose Fat | Liz Plosser 26.05.2026 1sa 2dkMost people think tracking their protein is enough. The science says what your body actually craves is something far more specific and the person making that argument spent 23 years inside legacy media watching the wellness industry sell women everything from "bikini body in two weeks" to canned protein soda. In this episode, I sit down with Liz Plosser, former Editor in Chief of Women's Health, where she oversaw brands reaching 44 million women. We break down why the nine essential amino acids are what your body is really after when you chase protein, why BCAAs are only a fraction of the picture, and why a study found four of the top six creatine gummies on Amazon contained zero creatine. Liz also opens up about her own supplement stack, her shift from endurance running to heavy lifting, and makes the case that testing instead of guessing is one of the most empowering moves you can make for your health. Then we go deep on the science most people get wrong: why aging women struggle to pull amino acids from food, how essential aminos protect lean muscle even on rest days and for those on GLP-1s, the new research on high-dose creatine for sleep deprivation and Alzheimer's, and why collagen may not deserve the hype. We also cover the menopause misinformation epidemic, the 2002 hormone study that terrified the world, and what Liz puts in her own morning protocol. This conversation will completely change how you think about protein, what you supplement, and how you fuel your brain and body. Reduce your risk of Alzheimer's with my science-backed protocol for women 30+: https://go.neuroathletics.com.au/youtube-sales-page Subscribe to The Neuro Experience for evidence-based conversations at the intersection of brain science, longevity, and performance. _____ TOPICS DISCUSSED 00:00 Intro: The Protein Myth and Why Amino Acids Are What Your Body Really Wants 00:56 Protein, Amino Acids, and How Much You Actually Need 03:23 The Nine Essential Amino Acids: The Real Building Blocks 06:03 BCAAs vs EAAs: Why a Subset Isn't Enough 11:50 23 Years in Wellness Media: What Liz Saw Change 14:18 The Menopause Conversation and Why It Exploded 23:17 Kion Aminos, Timing, and Whether It Counts Toward Your 100g 26:46 Liz's Daily Routine: Aminos, Creatine, and the Morning Glass of Water 27:42 Can You Take Aminos While Fasting? 29:50 Do Aminos Preserve Lean Mass on Rest Days and on GLP-1s? 36:19 Leaving Legacy Media and Finding a New Mission 39:14 The New Creatine Research: Sleep, Dosing, and Alzheimer's 43:24 How Creatine Reaches the Brain and the Case for 10 Grams 44:48 Creatine for Mood and Depression 46:12 Collagen: Does It Actually Deserve the Hype? 49:40 The Creatine Gummy Scandal: Four of Six With Zero Creatine 51:27 Coffee, Cans, and Why Bioavailability Matters 54:50 Creatine, Electrolytes, and the 1990s Bodybuilding Hack 57:54 Liz's Morning Protocol and Owning Your AM _______ Thank you to our sponsors Kion: visit http://getkion.com/neuro for 20% off Function Health: https://www.functionhealth.com/louisanicola Timeline: https://www.timeline.com/partners/neuro-athletics AirDoctor: https://www.AirDoctorPro.com use promo code NEURO for up to $300 off Qualia Life: https://www.qualialife.com/Neuro for an additional 15% off on top of the 50% BASED Bodyworks: https://basedbodyworks.com/ and use code NEURO for 20% off _______ I’m Louisa Nicola - clinical neurophysiologist - Alzheimer’s prevention specialist - founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain- reducing Alzheimer’s risk - and staying mentally sharp for life, you’re in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices
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Why Breast Cancer Survivors Are Aging 20 Years Faster (And Doctors Don't Care) 19.05.2026 1sa 11dkMost people think breast cancer treatment ends when the tumor is gone. Science says that's where the real damage often begins, and the woman making that argument was diagnosed at 28, lost her mother to ovarian cancer the same year, and turned her own dismissal by the medical system into a specialization that now treats women nobody else will touch. In this episode, I sit down with Dr. Corinne Menn Board Certified OBGYN, breast cancer survivor, and one of the few specialists in the world treating menopause in cancer survivors. We break down why 80% of women diagnosed with breast cancer have no strong family history, why tamoxifen and aromatase inhibitors quietly devastate brain, bone, and sexual health, and why telling a woman with severe vaginal atrophy to use coconut oil is not evidence-based medicine. Dr. Corinne also opens up about her own diagnosis, her premature menopause at 28, the truth about hormone replacement therapy after breast cancer, and the BRCA, ApoE4, and surgical menopause snowball nobody is putting together for patients. This conversation will completely change how you think about breast cancer, menopause, and the women's health crisis hiding in plain sight. Reduce your risk of Alzheimer's with my science-backed protocol for women 30+: https://go.neuroathletics.com.au/youtube-sales-page Subscribe to The Neuro Experience for evidence-based conversations at the intersection of brain science, longevity, and performance. _____ TOPICS DISCUSSED 00:00 Intro: Why Nobody Is Coming to Save Breast Cancer Survivors 01:05 Karin's Origin Story: Diagnosed at 28, Losing Her Mom, and Premature Menopause 03:06 The 85% Cure Rate Lie: Why Survival Comes at a Brutal Cost 06:13 Breast Cancer Is Not One Disease: Why 80% Have No Family History 08:14 BRCA1, BRCA2, and the Genetic Mutations Most Women Never Get Tested For 13:14 Karin's Own Genetic Test Story and Why 23andMe Is Not Enough 15:07 BRCA1 vs BRCA2: Age of Onset and When to Remove Ovaries 17:30 The Biology of Estrogen: Why Estrogen Does Not Cause Breast Cancer 23:40 Birth Control, Breastfeeding, and the Real Risk Factors 26:17 Alcohol, Inflammation, and the Toxins Driving Cancer Rates 27:46 Tamoxifen Explained: What It Does to Your Brain, Bones, and Body 34:23 Aromatase Inhibitors: Putting Your Estrogen in the Basement 37:15 Where Women Go When No Doctor Will Help Them 41:17 Oophorectomy, Early Menopause, and the 6 to 12% of Women Affected 44:26 Why Black Women Face the Highest Risk and the Least Care 46:20 The ApoE4, BRCA, and Surgical Menopause Snowball 48:02 Coconut Oil Is Not Medicine: The Vaginal Estrogen Truth 50:35 HRT Denial and the Myths Keeping Women From Treatment 51:13 Who Owns the Breast Cancer Survivor After Treatment Ends 54:18 Why the System Fails: Reimbursement, Resources, and Survivorship Gaps 01:00:07 Can You Be on Tamoxifen and Hormone Replacement Therapy? 01:03:26 Three Neurologists, One Tau Test, and the Dementia Dismissal 01:06:26 Positive Stories: Women Who Took Back Their Health and Won 01:09:16 The One Wish: Valuing Ovarian Function Beyond Reproduction _______ Thank you to our sponsors KetoneIQ: https://ketone.com/NEURO for 30% OFF DailyBasis: https://www.dailybasislife.com/NEURO for 50% off first month IQBARS: https://www.eatiqbar.com/ Biologica: https://biologica.com/NEURO Up to 32% off first subscription order Cure Hydration: https://www.curehydration.com/ Use code NEURO gets 20% off Honey Love: https://www.honeylove.com/NEURO Save 20% Off Honeylove #honeylovepod _______ I’m Louisa Nicola - clinical neurophysiologist - Alzheimer’s prevention specialist - founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain- reducing Alzheimer’s risk - and staying mentally sharp for life, you’re in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices
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5 ONE MINUTE HABITS That REVERSE Brain Aging (Science Explained) 12.05.2026 1sa 8dk*Reduce your risk of Alzheimer's with my science-backed protocol for women 30+:*https://tinyurl.com/55c24w66 Most people think tracking your brain is science fiction. The truth is, the technology to measure your brainwaves, train your focus, and deepen your deep sleep already fits inside a sleek little headband and the woman who built it has been studying neuroplasticity since long before consumer neurotech existed. In this episode, I sit down with Ariel Garten, neuroscientist, psychotherapist, and co-founder of Muse, the brain-sensing wearable backed by the world's largest consumer EEG data set. We break down what brainwaves actually are, why your individual alpha peak frequency is one of the most underrated markers of cognitive aging, and how just five minutes of focused attention meditation per day can make your brain look 7.5 years younger. Ariel walks me through sleep spindles as the single greatest predictor of brain age, how the glymphatic system clears amyloid beta during deep sleep, and why hemispheric specialization shows up so differently in male and female anxiety. We also get into Muse's foundation brain model, novel biomarkers for Parkinson's and Alzheimer's, the digital sleeping pill, and her mission to make sure no one is jailed by the prison of their own mind. This conversation will change how you think about your brain, your sleep, and what cognitive longevity actually requires. Subscribe to The Neuro Experience for evidence-based conversations at the intersection of brain science, longevity, and performance. _____ *TOPICS DISCUSSED*(00:00:00) Intro: Inside the Brain Sensing Headband Changing Neuroscience (00:05:17) What an EEG Actually Measures and Your Brainwaves Explained (00:13:20) Alpha Waves, Flow State, and Why It's Easier to Reach Than You Think (00:23:11) Peak Alpha Frequency: The Refresh Rate of Your Brain (00:29:25) The Meditation Study That Made Brains Look 7.5 Years Younger (00:38:30) Sleep Spindles: The Single Greatest Predictor of Brain Age (00:43:30) Deep Sleep, Delta Waves, and the Glymphatic Power Wash (00:48:11) Muse's Digital Sleeping Pill and Deep Sleep Boost (01:01:21) fNIRS, Blood Flow Training, and the Athena Owl Experience (01:04:23) The Foundation Brain Model and Novel Biomarkers for Alzheimer's _______ *Thank you to our sponsors*Function Health: https://www.functionhealth.com/louisanicolaTimeline: https://www.timeline.com/partners/neuro-athleticsJones Road Beauty: https://www.jonesroadbeauty.com and use code NEUROLifeboost Coffee: https://lifeboostcoffee.com/ and use code NEURO for 10% offMomentum: https://momentumshake.com/neuro Get Free Welcome Kit + Travel Collection — $70 valueIQBARS: https://www.eatiqbar.com/ _______ I’m Louisa Nicola - clinical neurophysiologist - Alzheimer’s prevention specialist - founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention.If you're committed to optimizing your brain- reducing Alzheimer’s risk - and staying mentally sharp for life, you’re in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0Instagram: https://www.instagram.com/louisanicola_/Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices
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How THIS Founder Built a $150M Brand Without Any Funding 05.05.2026 1sa 12dkMost people think building a billion-dollar consumer brand requires a Stanford MBA, a celebrity co-sign, and a war chest of venture capital. The reality is messier. The person making that case mixed nootropics in his college dorm room, helped his paralyzed best friend find his edge again with the same compounds, and turned a piece of gum into one of the fastest-growing functional brands in America. In this episode, I sit down with Kent Yoshimura, neuroscientist, martial artist, muralist, and co-founder of Neuro Gum. We break down why the founder's identity matters more than the ingredient list, why cold compression makes most creatine gummies a scam, and why nano-influencers will quietly outperform every Kardashian-tier post by 2027. Kent also opens up about the trademark lawsuit that nearly killed the company, the Daniel Lubetzky DM that ended a war of attrition in a single message, the 25,000-creator Discord running Neuro's TikTok flywheel, the $10 million raise that built the team, and what he would do with $10,000 if he had to start a brand over today. This conversation will completely change how you think about cognitive performance, founder credibility, and what it takes to build a brand people trust over an algorithm. Reduce your risk of Alzheimer's with my science-backed protocol for women 30+: https://go.neuroathletics.com.au/youtube-sales-page Subscribe to The Neuro Experience for evidence-based conversations at the intersection of brain science, longevity, and performance. _____ TOPICS DISCUSSED 00:00 Intro: Mixing Supplements in a Dorm Room and the Birth of Neuro Gum 04:27 Martial Arts, Triathlon, and What Elite Sport Teaches You About Business 14:08 Ryan's Snowboarding Accident and the Accessibility Mission 24:03 Cold Compression, Why Creatine Gummies Are a Scam, and the Melatonin Myth 30:23 The 2020 Inflection Point: CVS, Shark Tank, and Joe Rogan 31:23 The TikTok Playbook: Posting Every Day for a Year With No Agency 42:19 The 25,000-Creator Community and Paying Out a Quarter Million a Month 46:27 The $300 Million Lawsuit and the Daniel Lubetzky DM That Saved Neuro Gum 53:11 Why Red Bull's Dietrich Mateschitz Is Kent's Hero 1:00:17 AI, One-Person Billionaires, and Why Humanity Is the New Commodity 1:03:44 First Principles for Anyone Starting a Brand Today 1:08:40 The End of Mega-Influencers and the Rise of Nano Trust 1:09:49 What He Would Do With 10,000 Dollars to Start a Brand Today _______ Thank you to our sponsors Pulsetto: https://pulsetto.tech/pages/NEURO or use Code NEURO for some off your order Huel: https://www.huel.com/neuro use promo code NEURO for 15% OFF (New Customers, Min. $75 purchase) KetoneIQ: https://ketone.com/NEURO for 30% OFF DailyBasis: https://www.dailybasislife.com/NEURO for 50% off first month _______ I’m Louisa Nicola - clinical neurophysiologist - Alzheimer’s prevention specialist - founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain- reducing Alzheimer’s risk - and staying mentally sharp for life, you’re in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices
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Why You Might Be Actually EATING Plastic without Even Knowing it 30.04.2026 53dkMost people think their kitchen is the safest place in their home. The truth is the opposite. The cookware you use every day, the cutting boards you trust, the utensils you stir with, even the coffee maker on your counter, may be quietly leaching forever chemicals, microplastics, and heavy metals into your food and into your brain. In this episode, I sit down with Jordan Nathan, founder and CEO of Caraway, the brand redefining what nontoxic actually means in the modern home. Jordan walks me through the night he called poison control after overheating a Teflon pan, the 2-year journey to launch a cookware line free of PFAS, and why six U.S. states have now banned forever chemicals in cookware. We unpack what PFAS, PFOA, and PTFE actually are, why they accumulate in fat tissue and cross the blood brain barrier, and why scratched pans, plastic cutting boards, and black nylon utensils are some of the most dangerous things in your kitchen. Then we go deep on the science. I break down the Nature Medicine 2025 study showing microplastics in human brain tissue at higher concentrations than the liver or kidney, with the highest accumulation found in dementia brains. We cover the rise of autoimmune disease, the credit card's worth of plastic the average person consumes every week, Caraway's third party testing for over 600 PFAS chemicals, and a full kitchen audit on a $1,000 budget covering induction vs gas, dishwasher dangers, and what's coming next as Caraway expands into the broader nontoxic home. This conversation will completely change how you think about what is in your kitchen, what is in your body, and what you can actually do about it. Reduce your risk of Alzheimer's with my science-backed protocol for women 30+: https://go.neuroathletics.com.au/youtube-sales-page Subscribe to The Neuro Experience for evidence-based conversations at the intersection of brain science, longevity, and performance. _____ TOPICS DISCUSSED 00:00 Intro: Plastic Is Hiding in Plain Sight in Your Kitchen 01:36 The Night Jordan Called Poison Control Over a Teflon Pan 05:06 PFAS, PFOA, and PTFE: What Forever Chemicals Actually Are 09:35 Why PFAS Accumulate in Fat Tissue and Cross the Blood Brain Barrier 13:31 The Birth of Caraway and What the Name Actually Means 17:50 Why 6 States Have Banned PFAS in Cookware 19:22 Third Party Testing: How Caraway Tests for 600+ PFAS Chemicals 23:10 The Steve Jobs Mentality: Industry Standards Aren't Our Standards 29:31 Scratched Pans, Plastic Cutting Boards, and the Hidden Risks 33:18 Microplastics Found in Human Brain Tissue: The 2025 Study 37:28 Caraway's Bestsellers and the Expansion Into the Whole Home 40:20 Cast Iron, Stainless Steel, and How to Choose Cookware 41:29 Why You Should Never Put Cookware in the Dishwasher 43:02 Gas vs Induction Stoves: Which One Is Actually Safer 44:30 The Full $1,000 Kitchen Audit: Where to Start 49:21 Black Plastic, Nylon Utensils, and the Truth About Takeout Containers 51:00 One Thing Jordan Wishes He Knew About the Average Kitchen _______ Thank you to our sponsors DailyBasis: https://www.dailybasislife.com/NEURO for 50% off first month JSHealth: https://jshealthvitamins.com and use code NEURO for 20% off BASED Bodyworks: https://basedbodyworks.com/ and use code NEURO for 20% off _______ I’m Louisa Nicola - clinical neurophysiologist - Alzheimer’s prevention specialist - founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain- reducing Alzheimer’s risk - and staying mentally sharp for life, you’re in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices
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Neurophysiologist: How To Boost Your Focus PERMANENTLY in Minutes 28.04.2026 1sa 3dkElon Musk is widely regarded as the benchmark of elite human performance. From a neuroscience perspective, he is something else entirely: by his own self-documentation across interviews and social media, he has become the most thoroughly traceable case of elite cognitive deterioration ever observed in real time. The same biology eroding his decision-making carries categorically different, and far more dangerous, consequences for a specific hormonal architecture, with a 15 year delay on the damage. In this solo episode, I conduct a forensic neuroscience breakdown of what chronic, extreme output actually does to the brain. I examine why the 100 hour workweek punishes rather than rewards the prefrontal cortex, how the glymphatic system clears neurotoxic byproducts like amyloid beta only during deep sleep, and what chronic cortisol does to the hippocampus, including measurable volumetric reduction visible on MRI. I walk through the 2025 Framingham Heart Study showing that elevated midlife cortisol predicted increased amyloid deposition 15 years later, but only in postmenopausal women, then break down the biomarker blueprint for sustained cognition (morning cortisol, HRV, fasting insulin), the three inputs that build a real cortisol buffer, and the first principles operating system that lets Musk run six companies without the context switching cost that would break most executives. Reduce your risk of Alzheimer's with my science-backed protocol for women 30+: https://go.neuroathletics.com.au/youtube-sales-page Subscribe to The Neuro Experience for evidence-based conversations at the intersection of brain science, longevity, and performance. _____ TOPICS DISCUSSED 00:00 Intro: The Most Documented Case of Cognitive Deterioration in Real Time 07:18 The Prefrontal Cortex: How High Performing Brains Hit a Biological Ceiling 14:06 The Amygdala Handoff: When Your Threat System Takes Over 15:16 The Glymphatic System: Why Your Brain Only Cleans Itself in Deep Sleep 21:49 Cortisol: The Molecule That Makes or Breaks the 100 Hour Workweek 24:00 What Chronic Cortisol Actually Does to the Hippocampus 29:09 The Framingham Data: Cortisol Predicts Alzheimer's in Women 15 Years Later 37:01 The Biomarker Blueprint: Morning Cortisol, HRV, and Fasting Insulin 43:59 Sleep Architecture: Why Duration Alone Will Not Save You 49:27 The Cortisol Buffer: VO2 Max, Resistance Training, and Morning Light 54:13 The Dopamine Architecture of Obsession and the Science of Flow 59:01 The Longitudinal Verdict: Greatness Without Biological Debt 01:01:49 The Three Non-Negotiables for Operating at Your A Phase _______ Thank you to our sponsors Function Health: https://www.functionhealth.com/louisanicola Timeline: http://timeline.com/NEURO AirDoctor: https://www.AirDoctorPro.com use promo code NEURO for up to $300 off _______ I’m Louisa Nicola - clinical neurophysiologist - Alzheimer’s prevention specialist - founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain- reducing Alzheimer’s risk - and staying mentally sharp for life, you’re in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices
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This Is What Exercise Actually Does to Your Brain 21.04.2026 1sa 11dkMost people think a brain scan is just a snapshot of what is wrong right now. Dr. Mistry has spent twenty years reading over 300,000 neuroimaging studies and what he has found is that your brain scan does not just show you the present. It reveals your past and with the right tools, it predicts your future. In this episode, I sit down with Dr. Mistry, a neuroradiologist and neuroimaging specialist, to break down exactly how AI is transforming what we can detect in the brain and why the window to intervene is decades earlier than anyone tells you. We cover the F1 car analogy that reframes every component of your central nervous system, why Alzheimer's disease begins twenty to thirty years before diagnosis, and how a volumetric MRI spotted a 2.2% hippocampal volume loss in a woman in her 50s that the human eye could not detect on two consecutive normal scans. This episode will change how you think about your brain scans, your cardiovascular health, and the daily decisions that are either protecting or silently degrading your most important organ. Reduce your risk of Alzheimer's with my science-backed protocol for women 30+: https://go.neuroathletics.com.au/youtube-sales-page Subscribe to The Neuro Experience for evidence-based conversations at the intersection of brain science, longevity, and performance. _____ TOPICS DISCUSSED 00:00 Intro: Your Brain Scan Reveals Your Past and Future 01:20 300,000 Scans and the Farmer With a 78-Year-Old Brain 05:44 Which Brain Scan Actually Tells You Something 08:52 The F1 Car Analogy for Understanding Your Brain 13:29 Brain Volume, the Hippocampus, and the Cerebellum 17:01 Alzheimer's Starts 20-30 Years Before Diagnosis 19:24 The Beta Amyloid PET Scan Explained 25:04 How AI Maps and Measures Your Brain Volume 28:13 The 2.2% Hippocampal Loss Two Normal Scans Missed 34:02 How Exercise Grows the Hippocampus by 2% 40:41 The Vascular Prevention Window Nobody Talks About 46:20 What LDL and ApoB Actually Mean for Brain Health 51:25 Can Lifestyle Changes Actually Flatten the Atrophy Curve 57:01 How to Advocate for a Brain Scan Through the Medical System 01:05:09 Stillness vs. Illness: What Separates Brains That Age Well _______ Thank you to our sponsors Daily Basis: https://www.dailybasislife.com/NEURO for 50% off your first month KetoneIQ: https://ketone.com/NEURO for 30% off Caraway: https://carawayhome.com/neuro10 for 20% off Kinsyn: https://kinsyn.com/neuro And use code "neuro" for 20% off your first subscription _______ I’m Louisa Nicola - clinical neurophysiologist - Alzheimer’s prevention specialist - founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain- reducing Alzheimer’s risk - and staying mentally sharp for life, you’re in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices
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What Most People NEED to Know About Black Plastics (Throw it Away Immediately! ) 14.04.2026 1sa 10dkMost people think allergies are seasonal annoyances and autoimmune disease is just genetic bad luck. The science says otherwise and the doctor making that argument has spent her career tracing both epidemics back to a cascade of well-intentioned medical decisions made thirty years ago that got it catastrophically wrong. In this episode, I sit down with Dr. Tania Elliott, board-certified in internal medicine and allergy and immunology, to break down why your immune system is not broken, it is confused. We cover how chronic stress triggers the same physiological response as a bacterial invasion, why 80% of autoimmune diseases occur in women, and what is actually driving the 1 in 3 allergy epidemic. Dr. Elliott reveals the institutional failure behind the 2001 peanut guidance, why the 0.2% peanut allergy rate in Israel versus 10% in the US is not a coincidence, and why nut-free schools may be quietly creating the next wave of food allergies. We also get into what Benadryl is actually doing to your brain, why food sensitivity tests sold through influencers are close to useless, the real reason adults are suddenly developing shellfish allergies, and why the black plastic container your lunch arrived in is a serious problem. This episode will change how you think about your immune system, your child's early exposures, and the everyday decisions quietly shaping your long-term health. Reduce your risk of Alzheimer's with my science-backed protocol for women 30+: https://go.neuroathletics.com.au/youtube-sales-page Subscribe to The Neuro Experience for evidence-based conversations at the intersection of brain science, longevity, and performance. _____ TOPICS DISCUSSED 00:00 Intro: Why Your Immune System Is Not Broken, It Is Confused 01:02 Dr. Tania Elliott's Mission: Empowering People Through Evidence 02:46 What Is the Immune System and What Does It Actually Do 05:53 Autoimmune Disease, Chronic Stress, and Why 80% of Cases Are in Women 13:55 What Chronic Stress Actually Does to Your Immune System at a Cellular Level 25:29 The 1 in 3 Allergy Epidemic: What Changed in the Last 30 Years 30:08 The Hygiene Hypothesis, Antibiotics, C-Sections, and the Microbiome Disaster 36:09 The 2001 Institutional Failure That Made the Peanut Allergy Crisis Worse 41:52 Don't Put Peanut Butter on Your Child's Cheek, Do This Instead 43:19 Israel vs. the US: 0.2% vs. 10% Peanut Allergy and What Bamba Proved 45:37 Why Nut-Free Schools May Be Creating the Next Allergy Epidemic 49:29 Health Misinformation and the Algorithm's Role in Health Extremism 51:37 Developing Allergies as an Adult and the Shellfish Allergy Epidemic Explained 55:30 New Allergy Treatments, Useless Food Sensitivity Tests, and Black Plastic Containers 1:05:04 How to Spot Allergy Symptoms in Babies and Young Children 1:07:56 Why Benadryl Should Be Pulled From the Market _______ Thank you to our sponsors Daily Basis: https://www.dailybasislife.com/NEURO for 50% off first month Function Health: https://www.functionhealth.com/louisanicola Timeline: http://timeline.com/NEURO Jones Road Beauty: https://www.jonesroadbeauty.com and use code NEURO Lifeboost Coffee: https://lifeboostcoffee.com/ and use code NEURO for 10% off Just Thrive: https://justthrivehealth.com/NEURO _______ I’m Louisa Nicola - clinical neurophysiologist - Alzheimer’s prevention specialist - founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain- reducing Alzheimer’s risk - and staying mentally sharp for life, you’re in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices
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Why You Keep Attracting The Wrong Person (and how to actually fix it) | Naomi 09.04.2026 58dkMost people think astrology is a personality quiz. This conversation will make you reconsider that entirely. Naomi Nama Bracha is one of the most sought-after birth chart readers working today. In this episode, she sits down with me for a live, cold read of my chart pulling from the exact position of the sky at the time of my birth to reveal things I've never had explained to me before. Not in therapy. Not in any other conversation. We break down what a birth chart actually is, why it's more mathematical than mystical, and what the planets, signs, and houses each represent. We go into the Saturn-Neptune conjunction that just occurred an event that happens once every 320 years and what it means for the collective and for your chart right now. I also bring the science: a 2015 Columbia University study of 1.7 million patients found birth month correlates with risk for nine types of heart disease, and a 2023 meta-analysis confirmed that being born in winter or spring carries a 5 to 8% higher risk of developing schizophrenia. We also cover what astrology can do that therapy cannot, how synastry charts reveal the truth about your relationships, and how to access your own birth chart for free. Reduce your risk of Alzheimer's with my science-backed protocol for women 30+: https://go.neuroathletics.com.au/brain-code Subscribe to The Neuro Experience for evidence-based conversations at the intersection of brain science, longevity, and performance. _____ TOPICS DISCUSSED 00:00 Naomi Reads Louisa's Birth Chart Live 01:28 Planets, Signs, and Houses Explained 07:25 What Is a Birth Chart 13:48 Saturn on the Sun and the 10th House of Work 16:06 Why People Seek Astrologers and Saturn Returns 18:19 Pisces Rising: The Most Sensitive Sign 22:12 Your Rising Sign as Your Entry Point Into the World 23:36 The Science Linking Birth Month to Disease Risk 27:11 The Saturn-Neptune Conjunction and Current World Events 30:05 Pisces Season and What It Means Personally 33:55 How the Conjunction Is Rewriting Louisa's Identity 37:46 Can Your Chart Predict the Next 5 to 10 Years 39:32 Louisa's 2026 Reading and the Zodiac Life Cycle 42:11 The Shadow of Pisces: Over Giving and Numbing 45:11 Spiritual Practices, Solitude, and the Gym as Ritual 47:40 Freewill vs. Fate in Astrology 50:03 The New Generation and the New Collective Dream 51:56 What Astrology Does That Therapy Cannot 55:19 Synastry Charts and Relationship Patterns _______ Thank you to our sponsors Just Thrive: https://justthrivehealth.com/NEURO for 20% off Warby Parker: https://WarbyParker.com/NEURO Jones Road Beauty: https://www.jonesroadbeauty.com and use Code NEURO _______ I’m Louisa Nicola - clinical neurophysiologist - Alzheimer’s prevention specialist - founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain- reducing Alzheimer’s risk and staying mentally sharp for life, you’re in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices
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Muscle Expert: Everyone Takes Ozempic But Nobody Knows What It Does to Your Muscles | Dr. Mike Israetel 07.04.2026 1sa 29dkMost people think going to the gym for aesthetics is shallow. Science says it's actually the most honest starting point you've got and the person making that argument built one of the most respected evidence-based fitness companies in the world, openly used steroids, and then had surgery to remove his love handles. In this episode, I sit down with Dr. Mike Israetel, PhD in Sport Physiology and co-founder of Renaissance Periodization. We break down why two 20 minute workouts a week can build genuine muscle, why compound movements beat isolation exercises for nearly everyone, and why yoga and Pilates will not get you the physique you're after. Mike also opens up about his own use of anabolic steroids and cosmetic surgery, and makes the case that aesthetics pursued honestly and without shame is one of the most empowering conversations in health. Then we go deep on the future of the human body: GLP-1s, myostatin inhibitors, retatrutide, and why Mike believes that by the 2040s, no disease we can identify today will still exist. We also cover AI-driven medicine, recursive self-improvement, the brain rot epidemic, and what's inside his upcoming book The Aesthetics Revolution. This conversation will completely change how you think about why you train, how you train, and what the human body is about to become. Reduce your risk of Alzheimer's with my science-backed protocol for women 30+: https://go.neuroathletics.com.au/youtube-sales-page Subscribe to The Neuro Experience for evidence-based conversations at the intersection of brain science, longevity, and performance. _____ TOPICS DISCUSSED 00:00 Intro: The Biggest Mistake Most People Make With Their Training 05:17 The 20-Minute Paired Exercise Program That Hits Every Muscle Group 22:34 Will Lifting Make Women Bulky? Debunking the Biggest Fear 30:24 Why Women Train Too Light and How to Fix It 35:05 Mike's Origin Story: 20 Years, RP, and Fighting Fitness Misinformation 37:28 Yoga, Pilates, and Why They Won't Give You the Physique You Want 47:18 Mike's Cosmetic Surgery: Removing Love Handles, Zero Regrets 53:11 The Aesthetics Revolution Book and the Future of Looking How You Want 59:38 GLP-1s: What Nobody Tells You 01:07:18 AI and the End of Disease: Why Mike Thinks the 2040s Changes Everything 01:16:25 Brain Rot, Literacy, and the Cognitive Cost of the Scroll Era 01:23:15 Personal AI as Life Coach: What's Coming by 2027 _______ Thank you to our sponsors KetoneIQ: https://ketone.com/NEURO for 30% OFF Kion: https://getkion.com/neuro for 20% off Pulsetto: https://pulsetto.tech/pages/NEURO or use Code NEURO for 20% off _______ I’m Louisa Nicola - clinical neurophysiologist - Alzheimer’s prevention specialist - founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain- reducing Alzheimer’s risk - and staying mentally sharp for life, you’re in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices
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Exercise Experts Reveal The 20-Minute Protocol That Actually Fights Aging 31.03.2026 58dkThis week, we're going to do something a little different. Six of our experts reveal what most people are getting completely wrong about exercise. One: the minimum effective dose for resistance training is shockingly low, just 3 to 6 sets per muscle group per week. Two: the biohacking tools everyone is obsessing over, hyperbaric chambers, red light beds, and ice baths, are built for elite athletes, not the general public. Three: jumping three times a week for just ten minutes can reverse osteopenia entirely, no weights required. Four: the zone two obsession gripping the fitness world right now is a cultural movement, not based on science. Five: muscle is your most powerful glucose sink, and the type two fibers you start losing in your early 30s are exactly what drives insulin resistance as you age. Six: you only need to touch high intensity exercise a handful of times a week paired with two days of resistance training to meaningfully train for longevity. Reduce your risk of Alzheimer's with my science-backed protocol for women 30+: https://go.neuroathletics.com.au/youtube-sales-page Subscribe to The Neuro Experience for evidence-based conversations at the intersection of brain science, longevity, and performance. _____ TOPICS DISCUSSED 00:00 Intro 00:57 Alan Aragon - The Truth About Resistance Training 13:14 Ben Bruno - Why Biohacking Is Overhyped 27:22 Dr. Vonda Wright - How To Reverse Bone Loss 29:49 Dr. Kristi - Why Zone 2 Is Not Based On Science 44:58 Dr. Stephanie Estima - How Muscle Loss Drives Insulin Resistance 55:11 Dr. Inigo San Millan - How To Actually Train For Longevity _______ Thank you to our sponsors IQBARS: https://www.eatiqbar.com/ Js Health: https://jshealthvitamins.com or Use code NEURO for 20% off Cellure: https://cellure.co/ or Use code NEURO for 20% Off Warby Parker: https://WarbyParker.com/NEURO KINSYN: https://kinsyn.com/neuro or Use code NEURO to Save 20% off your first subscription _______ I’m Louisa Nicola - clinical neurophysiologist - Alzheimer’s prevention specialist - founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain- reducing Alzheimer’s risk - and staying mentally sharp for life, you’re in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices
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Gut Expert: Eating THIS Everyday Protects The Gut from Diseases | Dr Karan 24.03.2026 1sa 2dkColorectal cancer is now the No.1 cause of death for people under 50 in the United States. When it is caught early, nine out of ten people survive. When it is caught late, only two out of ten do. Yet most people are not screening, not eating enough fiber, and have no idea how rapidly the gut microbiome is collapsing in modern populations. I sat down with Dr. Karan Rajan, NHS surgeon, gut health expert, and founder of Loam Science, to break down the real biology behind the gut microbiome and why it may be one of the most powerful levers we have for longterm health. We cover the rising colorectal cancer epidemic in young people, why fiber is the single most important thing you can do for your colon, and how the microbiome connects to your brain, heart, hormones, immune system, and even your skin. Dr. Karan also explains how stress, poor sleep, NSAIDs, antibiotics, and proton pump inhibitors silently destroy the gut lining, why the carnivore diet starves your microbiome, the emerging link between gut health and endometriosis, and what the science actually says about microbiome testing, GLP-1 peptides, and supplement quality. Reduce your risk of Alzheimer's with my science-backed protocol for women 30+: https://go.neuroathletics.com.au/youtube-sales-page Subscribe to The Neuro Experience for evidence-based conversations at the intersection of brain science, longevity, and performance. _____ TOPICS DISCUSSED 00:00 Colorectal Cancer Is Now the #1 Killer Under 50 01:24 Why Early Screening Changes Everything 03:19 The Gut Microbiome Explained Simply 05:51 Why Fiber Is the Rent for Your Colon 11:32 The Hadza Tribe and What 100g of Fiber a Day Does 18:45 The Carnivore Diet and What It Does to Your Gut 24:10 Stress, the Vagus Nerve, and Gut Dysfunction 31:20 Sleep, Circadian Clocks, and Your Bowel Health 33:06 The Gut-Cancer Connection 34:12 Cholesterol, the Gut-Heart Axis, and LDL 38:50 Estrogen, Perimenopause, and the Microbiome 43:15 Endometriosis and the Microbiome Trial 48:30 Leaky Gut, NSAIDs, Antibiotics, and PPIs 53:25 GLP-1 Peptides, Semaglutide, and What the Research Says 55:38 Why Supplement Quality Is Mostly Unregulated _______ Thank you to our sponsors Function Health: https://www.functionhealth.com/louisanicola Timeline: http://timeline.com/NEURO Wayfair: https://www.wayfair.com/ Cheers Health: https://CheersHealth.com/NEURO Use code NEURO for 20% off Jones Road Beauty: https://www.jonesroadbeauty.com Use code NEURO BASED Bodyworks: https://basedbodyworks.com/ Use code NEURO for 20% off _______ I’m Louisa Nicola - clinical neurophysiologist - Alzheimer’s prevention specialist - founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain- reducing Alzheimer’s risk - and staying mentally sharp for life, you’re in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices
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What Women Need to Know About Longevity Before It’s Too Late | Dr. Amy Killen 17.03.2026 1sa 3dkThe moment a woman’s hormones begin to decline, the entire body starts aging faster. The brain, heart, bones, immune system, and metabolism are all affected by a single biological shift most doctors barely explain. I sat down with Dr. Amy Killen, physician and leading expert in regenerative and longevity medicine, to explore the science of female aging and why ovarian health may be the true driver of how long women live. We break down the real biology behind menopause, why estrogen is far more than a reproductive hormone, and how hormone loss can accelerate cardiovascular disease, cognitive decline, bone loss, and systemic inflammation. Dr. Killen also explains the emerging science behind hormone replacement therapy, the misunderstood relationship between estrogen and breast cancer risk, and why many doctors still are not properly trained to treat menopause. We discuss stem cells, mitochondrial health, and the growing interest in therapies like hyperbaric oxygen, peptides, red light therapy, and plasma exchange, and what the evidence actually says. Reduce your risk of Alzheimer's with my science-backed protocol for women 30+: https://go.neuroathletics.com.au/youtube-sales-page Subscribe to The Neuro Experience for evidence-based conversations at the intersection of brain science, longevity, and performance. _____ TOPICS DISCUSSED 00:00 Why Ovarian Aging Impacts Lifespan 01:24 Why Dr. Amy Killen Focuses on Women’s Longevity 03:19 What Longevity Actually Means in Medicine 04:20 Stem Cells and Regenerative Medicine Explained 05:51 How Stem Cells Help Repair and Communicate With Tissue 11:32 Hormones, Perimenopause, and Rapid Aging 18:45 Why the Ovaries Are the “Peacekeepers” of Aging 24:10 Hormone Replacement Therapy Explained 31:20 Vaginal Estrogen vs Systemic Estrogen 38:50 Testosterone Therapy in Women 43:15 Longevity Therapies and Mitochondrial Health 48:30 Red Light Therapy, Hyperbaric Oxygen, and Recovery 50:54 Peptides and the Lack of Long-Term Safety Data 53:25 Therapeutic Plasma Exchange and Longevity Research 55:38 The Estrogen and Immune System Connection _______ Thank you to our sponsors Ketone-IQ: https://ketone.com/NEURO Cellure: https://cellure.co/ Use code NEURO Ka’Chava: https://kachava.com Use code NEURO for 15% off your first order Just Thrive: https://justthrivehealth.com/NEURO _______ I’m Louisa Nicola - clinical neurophysiologist - Alzheimer’s prevention specialist - founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain- reducing Alzheimer’s risk - and staying mentally sharp for life, you’re in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices
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Exercise Expert Reveals: The One Thing Blocking Women From Burning Fat Faster 10.03.2026 1sa 5dkZone two has been sold to you as the gold standard for mitochondrial health, fat burning, and longevity. But what if it was built on culture, not science. In this episode, I sit down with Kristi Storoschuk, a PhD researcher whose work is challenging some of the biggest claims in the exercise world right now. We break down why zone two training lacks the scientific evidence everyone assumes it has, why higher intensity zones three and four are actually more potent for mitochondrial adaptation, and why the 80/20 training split from elite athletes was never designed for someone exercising four days a week. We also get into why fasting doesn't activate the same cellular pathways in humans as it does in rodents, why cortisol from exercise is not the same as chronic stress, the truth about fasted exercise for women, and what lactate actually tells us about our metabolic health. Kristi also shares her current research in collaboration with Dr. Andy Galpin and Dr. Tommy Wood on whether lactate threshold can serve as a non-invasive proxy for mitochondrial content. This conversation will completely change how you think about every cardio session you've ever done. Reduce your risk of Alzheimer's with my science-backed protocol for women 30+: https://go.neuroathletics.com.au/youtube-sales-page Subscribe to The Neuro Experience for evidence-based conversations at the intersection of brain science, longevity, and performance. _____ TOPICS DISCUSSED 00:00 Intro: Was Zone Two Built on Culture, Not Science? 03:19 The Three Exercise Intensity Domains (Not Five Zones) 08:00 Zone Two and Fat Burning: What the Research Actually Shows 12:00 Why Women Are Being Scared Away from Zone Three and Four 20:45 Fasting in Rodents vs. Humans: The Research That Changed Everything 24:00 Fasted Exercise and Cortisol: The Real Story for Women 29:00 What Lactate Actually Tells Us About Mitochondrial Health 37:00 VO2 Max, Mitochondria, and Longevity 43:30 Exercise as Your Daily Metabolic Reset 49:00 The Best Cardio Prescription for Healthspan 55:30 How a 73 Year Old Should Think About High Intensity 58:00 How to Know What Zone You're In Without a Monitor 01:02:00 Sex Differences in Exercise: What the Data Actually Says _______ Thank you to our sponsors Function health: https://www.functionhealth.com/louisanicola Timeline: http://timeline.com/NEURO Jones Road Beauty: https://www.jonesroadbeauty.com And Use code NEURO Lifeboost coffee : https://lifeboostcoffee.com/ and Use code NEURO for 10% off Just Thrive: https://justthrivehealth.com/NEURO _______ I’m Louisa Nicola - clinical neurophysiologist - Alzheimer’s prevention specialist - founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain- reducing Alzheimer’s risk - and staying mentally sharp for life, you’re in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices
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Longevity Surgeon: The Biomarkers That Predict If You'll Get Cancer or Alzheimer's 04.03.2026 1sa 12dkThe surgeon who spent 12 to14 hours a day in the operating room developed diabetes, uncontrolled high blood pressure, and an autoimmune disease that was eating away at his skull and it forced him to confront what medical school never taught him about actually staying healthy. I sat down with Dr. Darshan Shah, board-certified surgeon, founder of Next Health (one of the largest longevity clinic networks in America), and a doctor who had to reverse his own chronic disease to understand the massive gap between Western medicine and the science of health. We explore why surgeons and physicians become some of the sickest people in healthcare, how functional medicine differs from what you learn in medical school, why biomarker testing matters more than your doctor's "you're fine" assessment, and what root cause medicine actually looks like in practice. Dr. Shah also breaks down the AI revolution happening in cardiovascular imaging with Cleerly scans, how his new AI health dashboard reads your bloodwork and medical records to give you proactive guidance, why Yamanaka factors could regenerate damaged nerves in the brain, and what the future of personalized, preventive medicine looks like when you combine AI with real biological data. Reduce your risk of Alzheimer's with my science-backed protocol for women 30+: https://go.neuroathletics.com.au/youtube-sales-page Subscribe to The Neuro Experience for evidence-based conversations at the intersection of brain science, longevity, and performance. _____ TOPICS DISCUSSED 00:00 Intro: The surgeon who developed the diseases he was treating 01:17 From trauma surgeon to longevity doctor: Dr. Shah's journey 04:18 Autoimmune disease, diabetes, and high blood pressure in a surgeon 10:30 Western medicine vs. the science of health 18:45 Why doctors don't learn prevention in medical school 35:20 Next Health clinics and democratizing longevity medicine 52:40 Biomarker testing and why "your labs are normal" is dangerous 01:03:52 AI health dashboard: uploading bloodwork and getting proactive guidance 01:06:45 Cleerly scans and reversing cardiovascular disease with AI imaging 01:10:08 Yamanaka factors, nerve regeneration, and the future of brain health _______ Thank you to our sponsors Function Health: https://www.functionhealth.com/louisanicola Timeline Mitopure: http://timeline.com/NEURO Ka'Chava: https://kachava.com and use code NEURO for 15% off your first order Wayfair: https://www.wayfair.com/ Fenix: https://www.fenixhealthscience.com/ Arey: https://arey.com/ and use code NEURO _______ I’m Louisa Nicola - clinical neurophysiologist - Alzheimer’s prevention specialist - founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain- reducing Alzheimer’s risk - and staying mentally sharp for life, you’re in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices
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Mitochondria Expert Reveals: Why Your Immune System Starts Failing in Your 40s (And How to Fix It) 03.03.2026 58dk80% of all autoimmune diseases occur in women, and no one can explain why. Cancer cells are always present in your body, but it's only when your T cells go into energy deficit that cancer starts overtaking the system. And here's what almost no one is talking about: the mitochondria in your immune cells are the reason MS, chronic fatigue, neurodegeneration, and even cancer progression happen when they happen. In this episode, I sit down with Dr. Anurag Singh, MD, PhD immunologist and Chief Medical Officer of Timeline who spent 20 years studying mitochondria and screened 4000 compounds from pomegranates to discover one molecule that changes cellular aging. We break down immunometabolism, the emerging field linking immune health and metabolism, why your T regulatory cells are the CEOs of your immune system, how mitochondrial dysfunction in immune cells triggers autoimmune conditions, and why rejuvenating mitochondria can get your immune system in check to defeat cancer. We also cover NAD+ (and why NMN and NR supplements don't work the way people think), the creatine sweet spot for muscle quality (500mg-1g, not the 5g everyone's taking), why Parkinson's is linked to paraquat, a mitochondrial toxin used in fertilizers and dry cleaning and how AI is fast-tracking the discovery of next-generation molecules for neurodegeneration. This conversation completely shifted how I think about immune health, brain protection, and what's actually driving the diseases we fear most. Reduce your risk of Alzheimer's with my science-backed protocol for women 30+: https://go.neuroathletics.com.au/youtube-sales-page Subscribe to The Neuro Experience for evidence-based conversations at the intersection of brain science, longevity, and performance. _____ TOPICS DISCUSSED 00:00 Intro: Why 80% of Autoimmune Diseases Occur in Women 01:24 Why Dr. Anurag Became an Immunologist 03:19 Immunometabolism: The Link Between Immune Health and Metabolism 04:20 T Cells, B Cells, and the Thymus Gland 05:51 MS and Autoimmune Disease: The T Regulatory Cell Problem 11:32 Mitochondrial Dysfunction and Immune Exhaustion 18:45 Cancer Cells and T Cell Energy Deficit 24:10 Urolithin A: Screening 4000 Pomegranate Compounds 31:20 Mitophagy and Autophagy: Cellular Housekeeping 38:50 NAD+ vs NMN and NR Supplements: What Actually Works 43:15 Creatine Dosing: The 500mg-1g Sweet Spot for Muscle Quality 48:30 Gut-Brain Connection and Neurodegeneration 50:54 Parkinson's Disease and Paraquat: The Mitochondrial Toxin 53:25 AI in Drug Discovery and Next-Generation Molecules 55:38 Skincare and Mitochondrial Health: Collagen Synthesis _______ Thank you to our sponsors KetoneIQ: https://ketone.com/NEURO for 30% OFF Caraway: Carawayhome.com/neuro10 Jones Road Beauty: https://www.jonesroadbeauty.com - Use code NEURO _______ I’m Louisa Nicola - clinical neurophysiologist - Alzheimer’s prevention specialist - founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain- reducing Alzheimer’s risk - and staying mentally sharp for life, you’re in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices
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Neurophysiologist: Why 30 Minutes of Exercise Changes 13 Types of Cancer 17.02.2026 36dkMost people fear cancer, but they're never given a clear explanation of what it actually is, how it progresses, or why metastasis, not the initial tumor, is what kills 90% of people with solid tumors. And here's what almost no one talks about…30 minutes of exercise per day can down-regulate 13 types of cancers. I break down the biology of cancer and metastasis in plain language, then walk you through the evidence linking exercise to cancer outcomes across prevention, treatment, and survivorship. I explain how cancer cells have to physically enter circulation and survive a hostile journey to metastasize, and here's the part that changed how I think about high-intensity exercise: as shear stress increases during vigorous exercise (zone 5, 90%+ max heart rate), survival of circulating tumor cells decreases. I also cover immune surveillance, metabolic signaling, and why this is deeply personal for me. Reduce your risk of Alzheimer's with my science-backed protocol for women 30+: https://go.neuroathletics.com.au/youtube-sales-page Subscribe to The Neuro Experience for evidence-based conversations at the intersection of brain science, longevity, and performance. Topics Discussed 00:00 Intro: Why Cancer Is What Scares Me Most 01:37 Why We're Having This Conversation 03:33 What This Episode Covers: The Three-Part Framework 06:21 What Cancer Actually Is: When Cells Break the Rules 07:25 Metastasis: The Part of the Story No One Explains 27:57 Shear Stress and Circulating Tumor Cells: The Zone 5 Effect 30:16 Immune Surveillance: How Exercise Mobilizes Killer Cells 30:51 Metabolic Signaling: Insulin, IGF-1, and Inflammation 32:16 Limitations: What the Evidence Can and Can't Tell Us 34:37 Practical Framework: Prevention, Treatment, and Survivorship 36:04 Closing: Exercise as Repeated Physiological Stress Thank you to our sponsors Ketone-IQ: https://ketone.com/NEURO IQ BARS: Text NEURO to 64000 to get 20% off all IQBAR products Cure Hydration: http://curehydration.com/NEURO Cellure: https://cellure.co/ and use code NEURO Arrey: https://arey.com/ and use code NEURO _______ I’m Louisa Nicola - clinical neurophysiologist - Alzheimer’s prevention specialist - founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain- reducing Alzheimer’s risk - and staying mentally sharp for life, you’re in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices
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Neuroscientist: Why Women Are Being Sold Untested Brain Drugs (The Peptide Lie) 10.02.2026 56dkThe peptide industry just hit $328 million in imports from China in nine months, and the fastest-growing buyers aren't bodybuilders. They're women in their 30s, 40s, and 50s who were told their labs look "fine" when they know something is deeply wrong.In this episode, I break down why peptides like BPC-157 and TB-500 are being aggressively marketed to women in perimenopause, why there isn't a single randomized controlled trial proving they're safe or effective in humans, and what the actual evidence says about brain fog, muscle loss, joint pain, and metabolic decline. I explore why the "your bloods are normal" dismissal has destroyed women's health, how hormone replacement therapy actually protects your brain when timed correctly, why GLP-1s work when peptides don't, and what protein, sleep, and resistance training do that no research chemical can replicate, because the foundations of brain health will never trend on TikTok, but they're the only things backed by decades of rigorous science. *Reduce your risk of Alzheimer's with my science-backed protocol for women 30+: * https://go.neuroathletics.com.au/youtube-sales-page Subscribe to The Neuro Experience for evidence-based conversations at the intersection of brain science, longevity, and performance. *TOPICS DISCUSSED* 00:00 Intro: Why women are the fastest-growing peptide buyers 07:01 Perimenopause reality: why "your labs look fine" is destroying women's health 15:20 What peptides actually are and the missing human evidence 31:00 Quality control disasters and documented side effects 39:50 What actually works: resistance training, protein, and muscle preservation 44:30 Hormone replacement therapy and brain protection 51:14 GLP-1 receptor agonists: evidence-based use vs. gray market risks *Thank you to our sponsors* Caraway: https://carawayhome.com/neuro10 Timeline Mitopure: http://timeline.com/NEURO Function Health: https://www.functionhealth.com/tcm/louisanicola _______ I’m Louisa Nicola - clinical neurophysiologist - Alzheimer’s prevention specialist - founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain- reducing Alzheimer’s risk - and staying mentally sharp for life, you’re in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices
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Why Most Women Are Taking Heart Medications Wrong - And Dying From It | Dr. Jayne Morgan 03.02.2026 1sa 10dkIt’s one of the most uncomfortable truths in modern medicine: women’s hearts have been misunderstood, under-researched, and misdiagnosed for decades. I sat down with Dr Jayne Morgan, cardiologist, heart health expert, and one of the leading voices calling out gender bias in cardiovascular medicine, to uncover why women’s heart attacks are still being missed - and what every woman needs to know to protect her brain and heart long before symptoms appear. We explore why women experience heart disease differently than men, how inflammation quietly damages blood vessels, the hidden heart attack signs doctors overlook, and why mammograms, pregnancy history, and menopause all hold critical cardiovascular clues. Dr Morgan explains why “gender-neutral” research has harmed women, how common medications can affect women differently, and why prevention needs to start earlier, not after the first cardiac event. Reduce your risk of Alzheimer’s with my science-backed protocol for women 30+: https://go.neuroathletics.com.au/youtube-sales-page Subscribe to The Neuro Experience for evidence-based conversations at the intersection of brain science, longevity, and performance. ______ TOPICS DISCUSSED 00:00 Intro: Why women’s heart disease is still misunderstood 02:18 How gender bias shaped modern cardiology 05:04 Why women’s heart attacks look different than men’s 08:12 The dangerous myth of “gender-neutral” medicine 11:30 Inflammation, blood vessels, and silent cardiovascular damage 15:02 Hidden heart attack signs on mammograms 18:45 Pregnancy history and long-term heart risk 22:10 Menopause, estrogen loss, and cardiovascular decline 26:40 Why standard heart medications can harm women 30:05 Beta blockers, blood pressure, and female physiology 33:50 The heart-brain connection and dementia risk 38:20 Viruses, shingles, and cardiovascular inflammation 42:05 Why women are dismissed in clinical settings 46:10 Prevention vs reaction in modern healthcare 49:30 What women should demand from their doctors ______ A huge thank you to my sponsors for supporting this episode. Check them out and enjoy exclusive discounts: IQBAR- Fuel your brain and body with IQBAR’s protein bars, hydration mixes, and mushroom coffees. Text NEURO to 64000 to get 20% off all IQBAR products plus free shipping. Cure Hydration - Clean, plant-based electrolytes with no added sugar, hydration that actually works. Get 20% off your first order at curehydration.com/NEURO with code NEURO. Jones Road Beauty- Effortless, skin-first makeup created by Bobbi Brown. Use code NEURO at jonesroadbeauty.com to get a free Cool Gloss with your first purchase. RHO Nutrition- Science-backed supplements designed to support cognitive performance and metabolic health. Visit rhonutrition.com and use code NEURO for exclusive savings. ______ I’m Louisa Nicola - clinical neurophysiologist - Alzheimer’s prevention specialist - founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain - reducing Alzheimer’s risk - and staying mentally sharp for life, you’re in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices
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