MIT OpenCourseWare: Free Courses from the institute
MIT OpenCourseWare
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MIT OpenCourseWare is a free and open online publication of educational materials from thousands of MIT courses, covering introductory through advanced graduate subjects. Each course on the OCW website includes a syllabus, instructional materials such as notes and reading lists, and learning activities like assignments and solutions. Some courses also offer videos, online textbooks, and faculty insights on teaching. There is no signup or enrollment, and no start or end dates, so learning is self-paced. The podcast shares insights, inspiration, videos, and educational resources from MIT OpenCourseWare for students, teachers, and curious learners.
Épisodes
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32. Nucleotide Metabolism 05.10.2026 1h 32minMIT 7.05 General Biochemistry, Spring 2020Instructor: Matthew Vander HeidenView the complete course: https://ocw.mit.edu/7-05S20YouTube Playlist: https://www.youtube.com/playlist?list=PLUl4u3cNGP62wNcIMfinU64CAfreShjptProfessor Vander Heiden introduces nucleic acid metabolism, then describes purine synthesis and uric acid, deoxyribonucleotides, pyrimidine synthesis, and the regulation of nucleic acid metabolism.License: Creative Commons BY-NC-SAMore information at https://ocw.mit.edu/termsMore courses at https://ocw.mit.eduSupport OCW at http://ow.ly/a1If50zVRlQWe encourage constructive comments and discussion on OCW’s YouTube and other social media channels. Personal attacks, hate speech, trolling, and inappropriate comments are not allowed and may be removed. More details at https://ocw.mit.edu/comments. Learn more about your ad choices. Visit megaphone.fm/adchoices -
Catalysts of Open: Philanthropy’s Role in the Open Education Movement 05.10.2026 1h 2minA conversation with supporters and partners from the open education funding community about the essential role that philanthropy has played—and continues to play—in driving forward a global movement centered on access, equity, and the belief that knowledge should be a public good.Panelists: Dr. Peter Baldwin, Dr. TJ Bliss, Dr. Catherine M. Casserly, Peter B. KaufmanYou and your support can shape the next 25 years of MIT OpenCourseWare. Help us reach 500 million more learners with free, open, and personalized MIT resources through our MIT Crowdfunding campaign: https://crowdfund.mit.edu/story/OpenCourseWare-S26 Learn more about your ad choices. Visit megaphone.fm/adchoices -
Lecture 2 Part 2: Vectorization of Matrix Functions 05.10.2026 37minMIT 18.S096 Matrix Calculus For Machine Learning And Beyond, IAP 2023Instructors: Alan Edelman, Steven G. JohnsonView the complete course: https://ocw.mit.edu/courses/18-s096-matrix-calculus-for-machine-learning-and-beyond-january-iap-2023/YouTube Playlist: https://www.youtube.com/playlist?list=PLUl4u3cNGP62EaLLH92E_VCN4izBKK6OEDescription: We can view matrix functions (matrix inputs/outputs) as “ordinary” multivariable calculus by “vectorizing” a matrix into a column vector.License: Creative Commons BY-NC-SAMore information at https://ocw.mit.edu/termsMore courses at https://ocw.mit.eduSupport OCW at http://ow.ly/a1If50zVRlQWe encourage constructive comments and discussion on OCW’s YouTube and other social media channels. Personal attacks, hate speech, trolling, and inappropriate comments are not allowed and may be removed. More details at https://ocw.mit.edu/comments. Learn more about your ad choices. Visit megaphone.fm/adchoices -
28. Pentose Phosphate Pathway 05.10.2026 1h 35minMIT 7.05 General Biochemistry, Spring 2020Instructor: Matthew Vander HeidenView the complete course: https://ocw.mit.edu/7-05S20YouTube Playlist: https://www.youtube.com/playlist?list=PLUl4u3cNGP62wNcIMfinU64CAfreShjptIn this lecture, Professor Vander Heiden begins with a review of the Calvin cycle, then discusses the pentose phosphate pathway involving transketolase and transaldolase as well as the oxidative PPP and the non-oxidative PPP. License: Creative Commons BY-NC-SAMore information at https://ocw.mit.edu/termsMore courses at https://ocw.mit.eduSupport OCW at http://ow.ly/a1If50zVRlQWe encourage constructive comments and discussion on OCW’s YouTube and other social media channels. Personal attacks, hate speech, trolling, and inappropriate comments are not allowed and may be removed. More details at https://ocw.mit.edu/comments. Learn more about your ad choices. Visit megaphone.fm/adchoices -
The Future of MIT Open Education 05.10.2026 1h 4minA forward-looking dialogue on the commitments and evolution of OCW and MIT’s open learning initiatives, including mobile learning, language translation, AI-enabled personalization and learning supports, and sustaining open education’s place in future knowledge landscapes.Panelists: Dr. Dimitris Bertsimas, Dr. Sarah Hansen, Curt Newton You and your support can shape the next 25 years of MIT OpenCourseWare. Help us reach 500 million more learners with free, open, and personalized MIT resources through our MIT Crowdfunding campaign: https://crowdfund.mit.edu/story/OpenCourseWare-S26 Learn more about your ad choices. Visit megaphone.fm/adchoices -
22. Glucogenesis/Carbohydrate Storage/TCA Cycle I 05.10.2026 1h 33minMIT 7.05 General Biochemistry, Spring 2020Instructor: Matthew Vander HeidenView the complete course: https://ocw.mit.edu/7-05S20YouTube Playlist: https://www.youtube.com/playlist?list=PLUl4u3cNGP62wNcIMfinU64CAfreShjptAfter a quick review of the regulation of glycolysis, Professor Vander Heiden discusses glycogen metabolism, fructose and galactose metabolism, and introduces the tricarboxylic acid cycle (TCA) cycle.License: Creative Commons BY-NC-SAMore information at https://ocw.mit.edu/termsMore courses at https://ocw.mit.eduSupport OCW at http://ow.ly/a1If50zVRlQWe encourage constructive comments and discussion on OCW’s YouTube and other social media channels. Personal attacks, hate speech, trolling, and inappropriate comments are not allowed and may be removed. More details at https://ocw.mit.edu/comments. Learn more about your ad choices. Visit megaphone.fm/adchoices -
14. P and NP, SAT, Poly-Time Reducibility 05.10.2026 1h 26minMIT 18.404J Theory of Computation, Fall 2020Instructor: Michael SipserView the complete course: https://ocw.mit.edu/18-404JF20YouTube Playlist: https://www.youtube.com/playlist?list=PLUl4u3cNGP60_JNv2MmK3wkOt9syvfQWYNOTE: There is no video for Lecture 13 as that was the day for the Midterm Exam.Quickly reviewed last lecture. Defined NTIME(t(n)) complexity classes and the class NP. Showed that COMPOSITES is in NP. Discussed the P versus NP question. Proved that acceptance problem for CFG is in P. Introduced the satisfiability problem SAT and polynomial-time reducibility.License: Creative Commons BY-NC-SAMore information at https://ocw.mit.edu/termsMore courses at https://ocw.mit.eduSupport OCW at http://ow.ly/a1If50zVRlQWe encourage constructive comments and discussion on OCW’s YouTube and other social media channels. Personal attacks, hate speech, trolling, and inappropriate comments are not allowed and may be removed. More details at https://ocw.mit.edu/comments. Learn more about your ad choices. Visit megaphone.fm/adchoices -
Will AI negate the need for science photography? 05.10.2026 9minScience Photographer Felice Frankel discusses the rapid improvements in generative AI and provides a reality check on just how much it can do in the field of scientific research.View the full Chalk Radio® episode: https://youtu.be/GqvBDc8wiu0?si=_543dMKOdnAWmU6zAI and Science Photography: https://youtu.be/0I8S6diyDjw?si=IOC2KV9CQDhl_ZgWView more from Felice Frankel on OCW: https://ocw.mit.edu/courses/res-10-001-making-science-and-engineering-pictures-a-practical-guide-to-presenting-your-work-spring-2026/ Learn more about your ad choices. Visit megaphone.fm/adchoices -
26. Oxidative Phosphorylation/Photosynthesis I 05.10.2026 1h 30minMIT 7.05 General Biochemistry, Spring 2020Instructor: Matthew Vander HeidenView the complete course: https://ocw.mit.edu/7-05S20YouTube Playlist: https://www.youtube.com/playlist?list=PLUl4u3cNGP62wNcIMfinU64CAfreShjptProfessor Vander Heiden continues the discussion of topics related to oxidative phosphorylation including redox shuttles, ATP accounting, and NADPH/glutathione, and then finishes with an overview of photosynthesis.License: Creative Commons BY-NC-SAMore information at https://ocw.mit.edu/termsMore courses at https://ocw.mit.eduSupport OCW at http://ow.ly/a1If50zVRlQWe encourage constructive comments and discussion on OCW’s YouTube and other social media channels. Personal attacks, hate speech, trolling, and inappropriate comments are not allowed and may be removed. More details at https://ocw.mit.edu/comments. Learn more about your ad choices. Visit megaphone.fm/adchoices -
Pool Testing Video 5 (No Audio) 05.10.2026 5minMIT 2.00AJ Exploring Sea, Space, and Earth: Fundamentals of Engineering Design, Spring 2009View the complete course: https://ocw.mit.edu/courses/2-00aj-exploring-sea-space-earth-fundamentals-of-engineering-design-spring-2009/YouTube Playlist: https://www.youtube.com/playlist?list=PLUl4u3cNGP61GIZ2gdRo6nr0Jzc14Z0ytPool testing at the Z-CenterLicense: Creative Commons BY-NC-SAMore information at https://ocw.mit.edu/termsMore courses at https://ocw.mit.eduSupport OCW at http://ow.ly/a1If50zVRlQWe encourage constructive comments and discussion on OCW’s YouTube and other social media channels. Personal attacks, hate speech, trolling, and inappropriate comments are not allowed and may be removed. More details at https://ocw.mit.edu/comments. Learn more about your ad choices. Visit megaphone.fm/adchoices -
Lecture 1 Part 2: Derivatives as Linear Operators 05.10.2026 55minMIT 18.S096 Matrix Calculus For Machine Learning And Beyond, IAP 2023Instructors: Alan Edelman, Steven G. JohnsonView the complete course: https://ocw.mit.edu/courses/18-s096-matrix-calculus-for-machine-learning-and-beyond-january-iap-2023/YouTube Playlist: https://www.youtube.com/playlist?list=PLUl4u3cNGP62EaLLH92E_VCN4izBKK6OEDescription: The key to generalizing derivatives is to realize that they are linear operators, relating small changes in a functions input to small changes in the output. License: Creative Commons BY-NC-SAMore information at https://ocw.mit.edu/termsMore courses at https://ocw.mit.eduSupport OCW at http://ow.ly/a1If50zVRlQWe encourage constructive comments and discussion on OCW’s YouTube and other social media channels. Personal attacks, hate speech, trolling, and inappropriate comments are not allowed and may be removed. More details at https://ocw.mit.edu/comments. Learn more about your ad choices. Visit megaphone.fm/adchoices -
23. TCA Cycle II 05.10.2026 1h 36minMIT 7.05 General Biochemistry, Spring 2020Instructor: Matthew Vander HeidenView the complete course: https://ocw.mit.edu/7-05S20YouTube Playlist: https://www.youtube.com/playlist?list=PLUl4u3cNGP62wNcIMfinU64CAfreShjptProfessor Vander Heiden dives deeper into the discussion of the TCA cycle and related topics including pyruvate oxidation, TCA cycle reactions, the output of the TCA cycle, anaplerosis, the glyoxylate cycle, and TCA cycle regulation. License: Creative Commons BY-NC-SAMore information at https://ocw.mit.edu/termsMore courses at https://ocw.mit.eduSupport OCW at http://ow.ly/a1If50zVRlQWe encourage constructive comments and discussion on OCW’s YouTube and other social media channels. Personal attacks, hate speech, trolling, and inappropriate comments are not allowed and may be removed. More details at https://ocw.mit.edu/comments. Learn more about your ad choices. Visit megaphone.fm/adchoices -
User-Developed Innovations in the Substance Use Disorder Space 05.10.2026 1h 3minMIT RES.SUD-01, Substance Use Disorders Venture Program, Spring 2025Instructors: Eric von Hippel, Hanna Adeyema View the complete course: https://ocw.mit.edu/courses/res-sud-01-substance-use-disorder-ventures-program-spring-2025/YouTube Playlist :https://www.youtube.com/playlist?list=PLUl4u3cNGP60O8-oSngUwSGC1J2EhNKsaProf. Eric von Hippel examines 'user innovators'—individuals with lived experience of substance use disorders—and the creative solutions they're developing to address real gaps in addiction recovery and support.License: Creative Commons BY-NC-SAMore information at https://ocw.mit.edu/termsMore courses at https://ocw.mit.eduSupport OCW at http://ow.ly/a1If50zVRlQWe encourage constructive comments and discussion on OCW’s YouTube and other social media channels. Personal attacks, hate speech, trolling, and inappropriate comments are not allowed and may be removed. More details at https://ocw.mit.edu/comments. Learn more about your ad choices. Visit megaphone.fm/adchoices -
30. Nitrogen/Amino Acid Metabolism I 05.10.2026 1h 36minMIT 7.05 General Biochemistry, Spring 2020Instructor: Matthew Vander HeidenView the complete course: https://ocw.mit.edu/7-05S20YouTube Playlist: https://www.youtube.com/playlist?list=PLUl4u3cNGP62wNcIMfinU64CAfreShjptProfessor Vander Heiden introduces nitrogen metabolism, describes the role of glutamate, discusses the transamination reactions and PLP, and goes through the urea cycle. License: Creative Commons BY-NC-SAMore information at https://ocw.mit.edu/termsMore courses at https://ocw.mit.eduSupport OCW at http://ow.ly/a1If50zVRlQWe encourage constructive comments and discussion on OCW’s YouTube and other social media channels. Personal attacks, hate speech, trolling, and inappropriate comments are not allowed and may be removed. More details at https://ocw.mit.edu/comments. Learn more about your ad choices. Visit megaphone.fm/adchoices -
3. Regular Pumping Lemma, Conversion of FA to Regular Expressions 05.10.2026 1h 16minMIT 18.404J Theory of Computation, Fall 2020Instructor: Michael SipserView the complete course: https://ocw.mit.edu/18-404JF20YouTube Playlist: https://www.youtube.com/playlist?list=PLUl4u3cNGP60_JNv2MmK3wkOt9syvfQWYQuickly reviewed last lecture. Showed conversion of DFAs to regular expressions. Gave a method for proving languages not regular by using the pumping lemma and closure properties. Introduced context free grammars (CFGs).License: Creative Commons BY-NC-SAMore information at https://ocw.mit.edu/termsMore courses at https://ocw.mit.eduSupport OCW at http://ow.ly/a1If50zVRlQWe encourage constructive comments and discussion on OCW’s YouTube and other social media channels. Personal attacks, hate speech, trolling, and inappropriate comments are not allowed and may be removed. More details at https://ocw.mit.edu/comments. Learn more about your ad choices. Visit megaphone.fm/adchoices -
Perspective on What It Takes to Be Successful as an Entrepreneur 05.10.2026 1h 17minMIT RES.SUD-01 Substance Use Disorders Ventures Program, Spring 2025Instructor: Bill AuletView the complete course: https://ocw.mit.edu/courses/res-sud-01-substance-use-disorder-ventures-program-spring-2025/YouTube Playlist: https://www.youtube.com/playlist?list=PLUl4u3cNGP60O8-oSngUwSGC1J2EhNKsaIn this video, entrepreneur and MIT Professor, Bill Aulet explores disciplined entrepreneurship and how to build sustainable companies that solve real-world problems. He draws on 15 years of MIT's successful educational program and features real success stories like BioBot Analytics.License: Creative Commons BY-NC-SAMore information at https://ocw.mit.edu/termsMore courses at https://ocw.mit.eduSupport OCW at http://ow.ly/a1If50zVRlQWe encourage constructive comments and discussion on OCW’s YouTube and other social media channels. Personal attacks, hate speech, trolling, and inappropriate comments are not allowed and may be removed. More details at https://ocw.mit.edu/comments. Learn more about your ad choices. Visit megaphone.fm/adchoices -
29. Lipid Synthesis 05.10.2026 1h 33minMIT 7.05 General Biochemistry, Spring 2020Instructor: Matthew Vander HeidenView the complete course: https://ocw.mit.edu/7-05S20YouTube Playlist: https://www.youtube.com/playlist?list=PLUl4u3cNGP62wNcIMfinU64CAfreShjptIn this session, Professor Vander Heiden describes fatty acid synthesis, fatty acid desaturation, the role of citrate, the regulation of fatty acid synthesis, lipid synthesis, cholesterol/statins, and ketone bodies. License: Creative Commons BY-NC-SAMore information at https://ocw.mit.edu/termsMore courses at https://ocw.mit.eduSupport OCW at http://ow.ly/a1If50zVRlQWe encourage constructive comments and discussion on OCW’s YouTube and other social media channels. Personal attacks, hate speech, trolling, and inappropriate comments are not allowed and may be removed. More details at https://ocw.mit.edu/comments. Learn more about your ad choices. Visit megaphone.fm/adchoices -
Invistics Case Study: Drug Diversion 05.10.2026 1h 38minMIT RES.SUD-01, Substance Use Disorders Venture Program, Spring 2025Instructors: Tom Knight, Erdin Beshimov View the complete course: https://ocw.mit.edu/courses/res-sud-01-substance-use-disorder-ventures-program-spring-2025/YouTube Playlist :https://www.youtube.com/playlist?list=PLUl4u3cNGP60O8-oSngUwSGC1J2EhNKsaTom Knight discusses Invistics Corporation, his former company that built cutting-edge software to detect and prevent drug diversion in healthcare systems.License: Creative Commons BY-NC-SAMore information at https://ocw.mit.edu/termsMore courses at https://ocw.mit.eduSupport OCW at http://ow.ly/a1If50zVRlQWe encourage constructive comments and discussion on OCW’s YouTube and other social media channels. Personal attacks, hate speech, trolling, and inappropriate comments are not allowed and may be removed. More details at https://ocw.mit.edu/comments. Learn more about your ad choices. Visit megaphone.fm/adchoices -
Lecture 8 Part 2: Automatic Differentiation on Computational Graphs 05.10.2026 1h 12minMIT 18.S096 Matrix Calculus For Machine Learning And Beyond, IAP 2023Instructors: Alan Edelman, Steven G. JohnsonView the complete course: https://ocw.mit.edu/courses/18-s096-matrix-calculus-for-machine-learning-and-beyond-january-iap-2023/YouTube Playlist: https://www.youtube.com/playlist?list=PLUl4u3cNGP62EaLLH92E_VCN4izBKK6OEDescription: Complicated computational processes can be expressed as “graphs” of computational steps that flow from inputs to outputs. Forward/reverse-mode automatic differentiation (AD) traverse in opposite directions, giving very different algorithms.License: Creative Commons BY-NC-SAMore information at https://ocw.mit.edu/termsMore courses at https://ocw.mit.eduSupport OCW at http://ow.ly/a1If50zVRlQWe encourage constructive comments and discussion on OCW’s YouTube and other social media channels. Personal attacks, hate speech, trolling, and inappropriate comments are not allowed and may be removed. More details at https://ocw.mit.edu/comments. Learn more about your ad choices. Visit megaphone.fm/adchoices -
21. Glycolysis II/Regulation 05.10.2026 1h 31minMIT 7.05 General Biochemistry, Spring 2020Instructor: Matthew Vander HeidenView the complete course: https://ocw.mit.edu/7-05S20YouTube Playlist: https://www.youtube.com/playlist?list=PLUl4u3cNGP62wNcIMfinU64CAfreShjptAfter recapping the steps of glycolysis, Professor Vander Heiden explores glycolysis further by evaluating the types and chemistry of the reactions and the regulation of the enzyme kinetics.License: Creative Commons BY-NC-SAMore information at https://ocw.mit.edu/termsMore courses at https://ocw.mit.eduSupport OCW at http://ow.ly/a1If50zVRlQWe encourage constructive comments and discussion on OCW’s YouTube and other social media channels. Personal attacks, hate speech, trolling, and inappropriate comments are not allowed and may be removed. More details at https://ocw.mit.edu/comments. Learn more about your ad choices. Visit megaphone.fm/adchoices
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