Intention to Treat

Episodi

• Trailer: NEJM Group Presents “Intention to Treat” 11.01.2023 3min

  From the New England Journal of Medicine, welcome to “Intention to Treat,” a podcast exploring the most complicated, perplexing, and fascinating issues facing medicine today. From groundbreaking research, to clinical advances, to personal stories from doctors and their patients, we give you a behind-the-scenes look at discoveries that are changing medical practice and provide you with the knowledge to thrive on the front lines of health care.
• Covid Vaccines — Playing the Long Game 25.01.2023 35min

  In this first episode of “Intention to Treat,” NEJM editor-in-chief Eric Rubin and his colleague at the FDA Vaccine Advisory Committee, Paul Offit, consider the achievements, limitations, and expectations of Covid vaccines.   A transcript of this episode is available at nejm.org/doi/full/10.1056/NEJMp2300222.
• Post-Roe Realities 08.02.2023 1h 2min

  In this episode of “Intention to Treat,” host Rachel Gotbaum takes us to Tennessee and Ohio, where new abortion bans are already harming patients and threatening their physicians.   A full transcript of this episode is available at nejm.org/doi/full/10.1056/NEJMp2300935.
• The Promise and Perils of Psychedelics 22.02.2023 1h

  In this episode of “Intention to Treat,” a study participant and a long-time investigator of hallucinogenic drugs for psychiatric conditions illuminate the effects of psilocybin in patients with depression. A full transcript of this episode is available at https://www.nejm.org/doi/full/10.1056/NEJMp2300936.
• The Fauci Phenomenon 08.03.2023 55min

  In this episode of “Intention to Treat,” some of the people who have worked closely with “America’s Doctor,” Anthony Fauci, offer insights into his character, values, accomplishments, and adventures over his decades of service at the NIH. A full transcript of this episode is available at nejm.org/doi/full/10.1056/NEJMp2300937.
• The Fauci Phenomenon, Part 2 22.03.2023 31min

  In this episode of “Intention to Treat,” Anthony Fauci sits down with host Rachel Gotbaum to discuss his long career in infectious disease and public health, what has motivated him, and the lessons he has learned and taught along the way. A full transcript of this episode is available at nejm.org/doi/full/10.1056/NEJMp2300938.
• Is Medicine Ready for AI? 05.04.2023 58min

  In this episode of “Intention to Treat,” Maia Hightower and Isaac Kohane join host Rachel Gotbaum to explore the promise and hazards of artificial-intelligence and machine-learning tools for both clinical and administrative uses in medicine. A full transcript of this episode is available at nejm.org/doi/full/10.1056/NEJMp2301939.
• Waiting on Prostate Cancer 19.04.2023 51min

  In this episode of “Intention to Treat,” host Rachel Gotbaum talks with patient Robert Schlamberg and Doctors Oladapo Yeku and Oliver Sartor about the option of watchful waiting in the care of men with early prostate cancer. A full transcript of this episode is available at nejm.org/doi/full/10.1056/NEJMp2303613.
• Race Relations and the First Paramedics 03.05.2023 58min

  This episode of “Intention to Treat” tells the story of the Freedom House Ambulance Service — a group of Black laypeople in Pittsburgh who underwent intensive training to become the first paramedics in the United States. A full transcript of this episode is available at nejm.org/doi/full/10.1056/NEJMp2303614.
• Lessons for a Pandemic 31.05.2023 21min

  In this episode of “Intention to Treat,” Drs. Harvey Fineberg and Eric Rubin take stock of the failures and successes of the Covid-19 response and elucidate their lessons for combating the next major public health threat, whatever it may be. A full transcript of this episode is available at nejm.org/doi/full/10.1056/NEJMp2303615.
• New Patient-Centered Options for Cancer Treatment 07.06.2023 37min

  “Intention to Treat” host Rachel Gotbaum talks with patient Awilde Peña and oncologist Deb Schrag about a new approach to treating rectal cancer that sidesteps the need for radiation, thereby avoiding long-term side effects and preserving fertility. A full transcript of this episode is available at nejm.org/doi/full/10.1056/NEJMp2303850.
• Unleashing CRISPR on Cancer 21.06.2023 52min

  In this episode of “Intention to Treat,” host Rachel Gotbaum explores the story of a teenager who’s now in remission from previously relapsed lymphoblastic leukemia and talks with the investigator who developed the “off-the-shelf” CAR T cells that made her treatment possible. A full transcript of this episode is available at nejm.org/doi/full/10.1056/NEJMp2303851.
• The Plight of Primary Care, Part 1 05.07.2023 54min

  This episode of “Intention to Treat,” explores the crisis in primary care in the United States, as increasing numbers or primary care physicians leave the field — driven out by corporatization, growing time pressure, and the inability to form the relationships that enable good care. A full transcript of this episode is available at nejm.org/doi/full/10.1056/NEJMp2303852.
• The Plight of Primary Care, Part 2 19.07.2023 53min

  What is driving U.S. physicians out of primary care — and keeping trainees from going into it in the first place? In this episode of “Intention to Treat,” host Rachel Gotbaum explores the breakdown of the system and possible ways to save it. A full transcript of this episode is available at nejm.org/doi/full/10.1056/NEJMp2305758.
• Prospects for Pain 02.08.2023 42min

  Some types of pain have proven resistant to all available medications. In this episode of “Intention to Treat,” Rachel Gotbaum talks with a patient with neuropathic pain and a researcher exploring new sodium-channel blockers that offer promise for such patients. A full transcript of this episode is available at nejm.org/doi/full/10.1056/NEJMp2305759.
• Preventing HIV’s Collateral Cardiovascular Damage 16.08.2023 50min

  People living with HIV have increased risk for cardiovascular disease (and other diseases of aging) earlier in life than those without HIV. In this episode of “Intention to Treat,” researcher Steven Grinspoon describes a new strategy for preventing collateral damage. A full transcript of this episode is available at nejm.org/doi/full/10.1056/NEJMp2307347.
• Obesity and Heart Failure 25.08.2023 38min

  Cardiologists now recognize that heart failure with preserved ejection fraction (HFpEF) may be caused by obesity. This episode of “Intention to Treat” examines new evidence that treating obesity can prevent HFpEF.   A full transcript of this episode is available at nejm.org/doi/full/10.1056/NEJMp2307349.
• Awakened Hope for Narcolepsy 13.09.2023 32min

  In this episode, a patient with narcolepsy describes her rough, long road to diagnosis and treatment, and a researcher elucidates both the condition and a new therapeutic direction. A full transcript of this episode is available at nejm.org/doi/full/10.1056/NEJMp2308308.
• What We Don’t Know about School Shooter Drills 27.09.2023 31min

  This episode peers into U.S. schools to examine a widespread but non–evidence-based approach to preparing children and staff for gun-violence incidents. A full transcript of this episode is available at nejm.org/doi/full/10.1056/NEJMp2308309.
• The Long Haul of Long Covid 11.10.2023 1h 3min

  This episode explores long Covid, an often-disabling but unexplained syndrome of post-acute sequelae of SARS-CoV-2. How is it affecting millions of people, and what is being done about it? A full transcript of this episode is available at nejm.org/doi/full/10.1056/NEJMp2309483.