Medicine Cases for Residents: 88 Diagnoses Inspired by UpToDate

Terminology, Classification, and Diagnosis of Acute Coronary Syndrome for Residents 19.09.2025 15min

This episode unpacks the essential terminology, classification, and diagnostic approaches for acute coronary syndrome (ACS), encompassing acute myocardial ischemia or infarction, all drawn directly from the comprehensive UpToDate article. It explores the evolving definitions of STEMI, NSTEMI, and unstable angina, the impact of high-sensitivity troponin on modern diagnostics, the Joint Task Force criteria for myocardial infarction, and the critical role of ECG in guiding management. Tailored for residents, the podcast delves into everything the UpToDate article covers on this foundational topic, occasionally wrapping up subtopics with “if you can’t remember everything, remember this” to highlight key takeaways. Tune in to build a roc

Initial Evaluation and Management of Suspected Acute Coronary Syndrome for Residents 19.09.2025 19min

This episode dives into the rapid evaluation and management of suspected Acute Coronary Syndrome (ACS), including myocardial infarction and unstable angina, in the emergency department, straight from the UpToDate article. It covers urgent steps like obtaining an ECG within 10 minutes, using troponin biomarkers, and differentiating STEMI from NSTEACS. Learn initial pharmacologic interventions, such as aspirin and nitroglycerin, and tackle challenges in diagnosing atypical presentations in women, older adults, and diabetic patients. Key subtopics conclude with “if you can’t remember everything, remember this” for critical takeaways. Listen to sharpen your ED skills, apply a tip on rounds, and share feedback!

Community-Acquired Pneumonia: Diagnosis, Management, and Prevention for Residents 17.08.2025 30min

This episode tackles Community-Acquired Pneumonia (CAP), a major health challenge, drawing directly from the comprehensive UpToDate article. It covers CAP’s definition, epidemiology, microbiology, pathogenesis, clinical presentations, and diagnostic approaches, including severity assessment and care setting decisions. Residents will gain insights into treatment strategies, complication management, prognosis, and key prevention methods like vaccination. Packed with ward-ready tips, the podcast occasionally wraps up subtopics with “if you can’t remember everything, remember this” to lock in critical points. Listen to master CAP diagnosis and management, apply a tip on rounds, and share feedback!

Blood cultures 17.08.2025 21min

This episode dives into the critical role of blood cultures in diagnosing bacteremia, covering everything from indications and collection techniques to laboratory analysis and result interpretation, all based on the comprehensive UpToDate article on this topic. Learn when to order blood cultures, how to minimize contamination, and how to distinguish clinically significant organisms from contaminants, with practical guidance for follow-up testing to monitor treatment. The podcast occasionally concludes key subtopics with "if you can’t remember everything, remember this," offering concise takeaways to solidify your understanding. Perfect for residents seeking to master this essential diagnostic tool.

Approach to the Patient with Dyspnea for Residents 17.08.2025 23min

This episode explores the complex symptom of dyspnea, or breathing discomfort, drawing from the detailed UpToDate article on its causes, assessment, and management. It covers the physiological and psychological factors behind dyspnea, including respiratory and cardiovascular etiologies, and provides a systematic approach to clinical evaluation and diagnostic testing for both acute and chronic presentations. With practical insights for residents, the podcast breaks down key concepts and occasionally wraps up subtopics with "if you can’t remember everything, remember this" to highlight critical points. A must-listen for navigating this common yet challenging symptom.

Cervical Subluxation in Rheumatoid Arthritis: Clinical Features and Management for Residents 19.08.2025 26min

This episode explores cervical subluxation in rheumatoid arthritis (RA), a critical complication involving partial vertebral dislocation due to RA-related joint destruction, as detailed in the comprehensive UpToDate article. It covers the epidemiology, risk factors, pathogenesis of joint and neurogenic injury, and clinical manifestations, from neck pain to severe neurologic deficits like myelopathy. Residents will learn about diagnostic imaging, including CT and MRI, and management approaches, such as surgical stabilization and preoperative care. The podcast occasionally concludes subtopics with “if you can’t remember everything, remember this” to highlight key takeaways. Essential listening for residents managing RA patients with neck complications.

Community-Acquired Pneumonia Treatment in Hospitalized Adults for Residents 17.08.2025 31min

This episode focuses on the management of community-acquired pneumonia (CAP) in hospitalized adults, based on the in-depth UpToDate article. It covers identifying CAP, determining care settings based on severity, selecting empiric antibiotics, and addressing drug-resistant pathogens like MRSA and Pseudomonas, alongside guidance on diagnostic testing, treatment duration, and prevention strategies. Tailored for residents, the podcast emphasizes practical decision-making and occasionally concludes subtopics with "if you can’t remember everything, remember this" to reinforce key takeaways. Essential listening for managing this common inpatient condition.

Outpatient Treatment of Community-Acquired Pneumonia in Adults for Residents 17.08.2025 23min

This episode delves into the outpatient management of community-acquired pneumonia (CAP) in adults, guided by the comprehensive UpToDate article. It explores initial diagnosis, care setting decisions, empiric antibiotic choices for healthy patients versus those with comorbidities, and follow-up care, including prevention strategies like vaccinations. Designed for residents, the podcast simplifies outpatient CAP management and occasionally wraps up subtopics with "if you can’t remember everything, remember this" to cement critical points. A valuable resource for treating mild CAP cases effectively.

Antimalarial Drugs: A Resident’s Guide 16.08.2025 22min

Dive into the world of antimalarial drugs with 88 Diagnoses! This episode unpacks everything from the UpToDate article on antimalarial drugs, covering mechanisms, resistance patterns, and toxicities. Learn how drugs like artemisinin derivatives, quinoline derivatives, and antifolates target the malaria parasite’s life cycle. With 3 snappy segments featuring catchy mnemonics, 4-5 ward-ready tips, relatable resident stories, and 3-4 ‘pause and think’ prompts, we wrap up with an interactive case study with a diagnostic twist. Each subtopic ends with “if you can’t remember everything, remember this” for quick recall. Listen now, apply a tip on rounds, and share your feedback to ace malaria management!

Acute Pancreatitis: Clinical Manifestations and Diagnosis for Residents 16.08.2025 22min

Dive into acute pancreatitis with this episode of 88 Diagnoses! Covering everything from the UpToDate article, we break down the inflammatory pancreatic condition—its classification (interstitial vs. necrotizing), severity (mild to severe), clinical symptoms like hallmark pain, and key diagnostic tools like serum lipase and CT/MRI. Expect 3 snappy segments with catchy mnemonics, 4-5 ward-ready tips, relatable resident stories, and 3-4 ‘pause and think’ prompts to sharpen your skills. Each subtopic wraps with “if you can’t remember everything, remember this!” We end with an interactive case study featuring a diagnostic twist. Listen now, apply a tip on rounds, and share your feedback to ace pancreatitis on the wards!

Severe Malaria: Treatment and Management for Residents 16.08.2025 19min

Tackle severe malaria in this high-energy 88 Diagnoses episode, drawn directly from the UpToDate article! Explore urgent diagnosis, antimalarial therapy with artesunate, and supportive care for complications like seizures, anemia, and acute kidney injury. Learn management protocols, including the Blantyre Coma Score and malarial retinopathy, with a focus on special populations like pregnant patients. Get 3 mnemonic-packed segments, 4-5 ward-ready tips, resident anecdotes, 3-4 ‘pause and think’ prompts, and a case study with a diagnostic twist. Each subtopic ends with “if you can’t remember everything, remember this!” Listen now, apply a tip on rounds, and share feedback to master severe malaria!

Acute Pancreatitis Management for Residents 16.08.2025 20min

Explore the management of acute pancreatitis in this 88 Diagnoses episode, drawn straight from the UpToDate article! Learn about initial assessment, fluid therapy, pain control, and severity-based care, plus how to tackle complications like necrosis and fluid collections. We cover interventions and treating root causes like gallstones or alcohol use. Enjoy 3 mnemonic-packed segments, 4-5 practical tips, resident anecdotes, 3-4 ‘pause and think’ prompts, and a case study with a diagnostic twist. Each subtopic ends with “if you can’t remember everything, remember this!” Listen now, apply a tip on rounds, and share your feedback to master pancreatitis management!

Approach to Infection in the Older Adult for Residents 14.08.2025 25min

This episode explores the critical topic of infections in older adults, drawing directly from the detailed insights provided by UpToDate. It covers why older adults are more susceptible to infections due to age-related physiological and immunological changes, as well as societal factors. The podcast highlights atypical presentations, modified fever definitions, and the need for a lower threshold of suspicion in this population. It also delves into antibiotic management, addressing altered pharmacokinetics, the risk of multidrug-resistant organisms, and the importance of antibiotic stewardship. Specific infectious syndromes like UTIs and pneumonia are discussed, along with immunization and travel considerations. Each subtopic concludes with the memorable phrase, “if you can’t remember everything, remember this,” ensuring residents retain the most critical points for effective patient care.

Fever of Unknown Origin in Adults: Etiologies for Residents 14.08.2025 18min

This episode tackles the diverse etiologies of Fever of Unknown Origin (FUO) in adults, based entirely on the comprehensive content from UpToDate. It defines FUO as a prolonged fever without an obvious cause after extensive evaluation and organizes its causes into five main categories: infections, rheumatologic conditions, neoplasms, miscellaneous causes, and undiagnosed cases. The podcast explores how epidemiology varies by geography, patient age, and even climate change’s impact on infectious causes, with examples like tuberculosis, adult-onset Still’s disease, cancers, and conditions such as sarcoidosis or factitious fever. Each subtopic is summarized with the key phrase, “if you can’t remember everything, remember this,” to help residents retain the essential diagnostic insights needed to navigate this challenging clinical puzzle.

Fever of Unknown Origin in Adults: Evaluation and Management for Residents 14.08.2025 16min

Unravel the mystery of Fever of Unknown Origin (FUO) in this 88 Diagnoses episode, straight from the UpToDate article! Dive into its four categories—classic, healthcare-associated, immunocompromised, and travel-associated—with a focus on systematic evaluation and management. Learn through detailed history-taking, physical exams, initial tests, and advanced diagnostics like PET/CT. Enjoy 3 mnemonic-driven segments, 4-5 ward-ready tips, resident anecdotes, 3-4 ‘pause and think’ prompts, and a case study with a diagnostic twist. Each subtopic wraps with “if you can’t remember everything, remember this!” Listen now, apply a tip on rounds, and share feedback to conquer FUO!

Clinical Manifestations, Diagnosis, and Differential Diagnoses of Polymyositis and Dermatomyositis: A Guide for Residents 13.08.2025 29min

Description: This episode provides a detailed exploration of the clinical manifestations, diagnosis, and differential diagnoses of dermatomyositis (DM) and polymyositis (PM), two immune-mediated myopathies, as outlined in the UpToDate articles. It covers the hallmark features of muscle weakness and inflammation, with a focus on DM’s distinctive skin manifestations and the variant clinically amyopathic DM (CADM). The podcast delves into epidemiology, key clinical signs, laboratory findings, and diagnostic approaches, including the role of imaging and muscle biopsies to distinguish DM and PM from conditions like inclusion body myositis (IBM) and immune-mediated necrotizing myopathy (IMNM). Grounded in UpToDate’s comprehensive insights, each subtopic wraps up with a practical takeaway, highlighted by "if you can’t remember everything, remember this," to support residents in mastering these complex conditions.

Dermatomyositis and Polymyositis: Treatment Approaches for Residents 13.08.2025 26min

Description: This episode explores the diagnosis and treatment of dermatomyositis (DM) and polymyositis (PM), two key subtypes of idiopathic inflammatory myopathies (IIMs), as comprehensively detailed in the UpToDate articles. It covers the full spectrum of therapeutic strategies, from initial treatments like glucocorticoids and conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) to advanced options for recurrent or resistant cases, such as intravenous immunoglobulin (IVIG) and rituximab. The podcast also delves into ancillary management approaches, including physical therapy and risk mitigation strategies, all based on the latest UpToDate insights. Each subtopic concludes with a key takeaway, summarized as "if you can't remember everything, remember this," to help residents retain critical information for clinical practice.

Overview of and Approach to the Idiopathic Inflammatory Myopathies: A Guide for Residents 12.08.2025 20min

This episode dives into the comprehensive overview of idiopathic inflammatory myopathies (IIMs), a group of rare conditions marked by progressive muscle weakness and inflammation, as detailed in the UpToDate article on the topic. It explores the key aspects of IIMs, including their subtypes, diagnostic approaches, and management strategies, providing a thorough understanding for medical residents. The podcast covers everything from clinical presentations to diagnostic tools and treatment options, all grounded in the latest UpToDate insights. Each subtopic is summarized with a practical takeaway, concluding with "if you can't remember everything, remember this" to reinforce key points for busy residents.

Approach to Diarrhea in Adults in Resource-Rich Settings for Residents 10.08.2025 30min

This episode of 88 Diagnoses delves into the comprehensive approach to managing diarrhea in adults within resource-rich settings, based entirely on the latest UpToDate article. It covers diagnostic strategies, treatment options, and management techniques tailored to environments with advanced medical resources. Crafted for medical residents, the podcast delivers practical, evidence-based insights to enhance clinical decision-making. Each key subtopic concludes with a memorable takeaway, "If you can't remember everything, remember this," to reinforce essential points for residents navigating complex patient care scenarios.

Approach to Diarrhea in Adults in Resource-Limited Settings for Residents 10.08.2025 17min

This episode of 88 Diagnoses explores the comprehensive approach to managing diarrhea in adults in resource-limited settings, drawing directly from the latest UpToDate article. It covers essential aspects of diagnosis, management, and treatment strategies tailored to environments with constrained resources. Perfect for medical residents, the podcast provides practical insights for effective patient care in challenging settings. Each key subtopic wraps up with a concise takeaway, "If you can't remember everything, remember this," to cement critical points for busy clinicians.