Movers and Shakers: a podcast about life with Parkinson's

Brain Bank 20.06.2026 28m

We can't quite believe it either but this week's episode was recorded at the UCL Brain Bank headed by Consultant Neurologist Tom Warner (also notably, Gillian's neurologist!). Thanks to expert guidance from Consultant Neuropathologist Zane Jaunmuktane and Clinical Research Fellow Patrick Cullinane we now know a considerable amount more about how banks like this one can use brains and other donations to conduct crucial research into Parkinson's Disease. What does the donation process look like? Friend and Parkinson's advocate, Jo Goodburn also joined us at the Queen Square site and shared with us her experience with the Imperial College London Brain Bank. We're organising our donation papers as we speak.Movers & Shakers is brought to you in partnership with Cure Parkinson's.Presented by Rory Cellan-Jones, Gillian Lacey-Solymar, Mark Mardell, Paul Mayhew-Archer, Sir Nicholas Mostyn and Jeremy Paxman.Produced and edited by Nick Hilton for Podot.Associate Producer: Lulu Goad & Ewan CameronMusic by Alex Stobbs Hosted on Acast. See acast.com/privacy for more information.

Walking Football 13.06.2026 24m

The Movers & Shakers are back in the pub to talk walking football. We're big fans of activities that help slow down the progression of Parkinson's Disease, particularly walking football; it may even rival ping pong (but not according to Gillian!). We didn't have a kick about in situ but we had some experts in to tell us all about it - and Rory went to his local club to give us a taste of the real thing. With us are the facilitators of the Parkinson’s Pioneers Women’s Walking Football Community, Annie Booth and Gemma Darvill, as well as member of the Whittington Health NHS Trust-Arsenal walking football programme, Jeremy Munday. If our guests don't inspire you to get moving, we don't know what will!Movers & Shakers is brought to you in partnership with Cure Parkinson's.Presented by Rory Cellan-Jones, Gillian Lacey-Solymar, Mark Mardell, Paul Mayhew-Archer, Sir Nicholas Mostyn and Jeremy Paxman.Produced and edited by Nick Hilton for Podot.Associate Producer: Lulu Goad & Ewan CameronMusic by Alex Stobbs Hosted on Acast. See acast.com/privacy for more information.

Risky Drugs 06.06.2026 39m

The BBC Radio 4 investigative programme 'Impulsive' shocked listeners across the world. Aired at the beginning of the year, 'Impulsive' revealed the devastating effects that the readily prescribed Parkinson's drugs, dopamine agonists, were having on their users, including causing hypersexuality and compulsive gambling, among other extremes. We've actually covered this topic before on Movers & Shakers, but the Radio 4 show brought the discussion back to light, so this week we're readdressing the risks associated with these drugs and what is being done to tackle them. The presenter of 'Impulsive', BBC Investigations correspondent Noel Titheradge, joined us, alongside one of the show's interviewees, and the co-founder of the Dopamine Agonist Action Group, Freddie Waite, to explain their journey to uncovering this 'shadow world'.Find out more about the Dopamine Agonist Action Group at www.impulsive.worldMovers & Shakers is brought to you in partnership with Cure Parkinson's.Presented by Rory Cellan-Jones, Gillian Lacey-Solymar, Mark Mardell, Paul Mayhew-Archer, Sir Nicholas Mostyn and Jeremy Paxman.Produced and edited by Nick Hilton for Podot.Associate Producer: Lulu Goad & Ewan CameronMusic by Alex Stobbs Hosted on Acast. See acast.com/privacy for more information.

World Parkinson's Congress in Phoenix, Arizona 30.05.2026 37m

Live from Phoenix, Arizona, for the World Parkinson's Congress 2026; it doesn't get much better than that if you ask us. We all took turns speaking to Parkinson's experts, whether that be on dancing, singing, or even finding a cure. There's almost no one we didn't try to speak to.. We even got to hear a fantastic comedy set from Paul, of which you will get a taste. Tune in to find out what we got up to and please do join us next time in Quebec!Movers & Shakers is brought to you in partnership with Cure Parkinson's.Presented by Rory Cellan-Jones, Gillian Lacey-Solymar, Mark Mardell, Paul Mayhew-Archer, Sir Nicholas Mostyn and Jeremy Paxman.Produced and edited by Nick Hilton for Podot.Associate Producer: Lulu GoadMusic by Alex Stobbs Hosted on Acast. See acast.com/privacy for more information.

Chelsea Flower Show 23.05.2026 35m

We're at the RHS Chelsea Flower Show! This year's event has a special focus on Parkinson's with the newly named Parkinson's Resilience Rose and the beautifully designed Parkinson's UK show garden. Unsurprisingly, the weather chose to be less than impressive for the day of our visit, but that didn't stop us from enjoying the sites and exploring the PUK plot with the help of the Head Gardeners and charity team. We spoke to a great range of plant experts and show attendees to find out what they thought about this significant year for PD at Chelsea.Presented by Rory Cellan-Jones, Gillian Lacey-Solymar, Mark Mardell, Paul Mayhew-Archer, Sir Nicholas Mostyn and Jeremy Paxman.Produced and edited by Nick Hilton for Podot.Associate Producer: Lulu GoadMusic by Alex Stobbs. Hosted on Acast. See acast.com/privacy for more information.

Try-Athlon 2026 16.05.2026 17m

To kick off our eighth season of Movers & Shakers, we're reporting to you from this year's Try-Athlon at the Twickenham Stoop. Organised by the Sports Parkinson's team, the annual event gathers together Parkies from far and wide to partake in a range of Parkinson's-friendly sports, from golf, to walking rugby, and even ballet (which one of our team members had a crack at!). We all put our trainers on, got moving, and recounted for this episode what we got up to. And a reminder that we've launched our campaign on the voice. Please send us your videos raising your Parky voice. Find out how to submit a clip on our website moversandshakerspodcast.com or check out previous submissions on our YouTube channel www.youtube.com/@TheParkyVoice.Movers & Shakers is brought to you in partnership with Cure Parkinson's.Presented by Rory Cellan-Jones, Gillian Lacey-Solymar, Mark Mardell, Paul Mayhew-Archer, Sir Nicholas Mostyn and Jeremy Paxman.Produced and edited by Nick Hilton for Podot.Associate Producer: Lulu GoadMusic by Alex Stobbs. Hosted on Acast. See acast.com/privacy for more information.

World Parkinson's Day 2026: Speak Out! 12.04.2026 13m

This year for our special World Parkinson's Day episode, we're coming to you live from Sutton (Mark's local branch) where they've arranged a day of amazing events to raise awareness of PD, with a particular focus. The voice will be our big campaign for 2026 and we're encouraging everyone to speak out (or sing out, if the desire takes you). Go to moversandshakerspodcast.com for more details on how to get involved!Movers & Shakers is brought to you in partnership with Cure Parkinson's.Presented by Rory Cellan-Jones, Gillian Lacey-Solymar, Mark Mardell, Paul Mayhew-Archer, Sir Nicholas Mostyn and Jeremy Paxman.Produced and edited by Nick Hilton for Podot.Sound mixing by Ewan Cameron.Music by Alex Stobbs. Hosted on Acast. See acast.com/privacy for more information.

Positivity 21.03.2026 20m

For the final episode of this seventh season of Movers and Shakers, we're looking on the bright side of life. Can positivity actually improve your condition? Or does it mask the hardship of life with PD? And what on earth is 'toxic positivity'? To discuss all this – and put the gang on a spectrum from Tigger to Eeyore – we've gathered at the Notting Hill pub for "a laugh and a moan".Movers & Shakers is brought to you in partnership with Cure Parkinson's.Presented by Rory Cellan-Jones, Gillian Lacey-Solymar, Mark Mardell, Paul Mayhew-Archer, Sir Nicholas Mostyn and Jeremy Paxman.Produced and edited by Nick Hilton for Podot.Sound mixing by Ewan Cameron.Music by Alex Stobbs. Hosted on Acast. See acast.com/privacy for more information.

Driving 14.03.2026 30m

Driving is something that people often take for granted – right up until they can't do it. With a Parkinson's diagnosis comes a lot of insecurity about being behind the wheel. When do you know if it's time to stop? How do you manage the DVLA's red tape? And what's the situation with those mythical blue badges? To run through these considerations, the Movers and Shakers are joined in the Notting Hill pub by an expert from Parkinson's UK.Movers & Shakers is brought to you in partnership with Cure Parkinson's.Presented by Rory Cellan-Jones, Gillian Lacey-Solymar, Mark Mardell, Paul Mayhew-Archer, Sir Nicholas Mostyn and Jeremy Paxman.Produced and edited by Nick Hilton for Podot.Sound mixing by Ewan Cameron.Music by Alex Stobbs. Hosted on Acast. See acast.com/privacy for more information.

Oral Health 07.03.2026 31m

We're sinking our teeth into another important issue this week, as we look at oral health and the role that it might play in Parkinson's. The Movers and Shakers are joined at the pub – where Paul is caught, live on microphone, snarfing a chocolate mousse – by experts from both dentistry and neurology to look at the chicken and (chocolate) egg question of whether PD affects oral health, or if bad oral hygiene could actually have impacts in the brain. It's not all about the blood/brain barrier though – this episode also features handy tips for keeping your teeth clean and preventing the negative side effects of gum disease.Movers & Shakers is brought to you in partnership with Cure Parkinson's.Presented by Rory Cellan-Jones, Gillian Lacey-Solymar, Mark Mardell, Paul Mayhew-Archer, Sir Nicholas Mostyn and Jeremy Paxman.Produced and edited by Nick Hilton for Podot.Sound mixing by Ewan Cameron.Music by Alex Stobbs. Hosted on Acast. See acast.com/privacy for more information.

The Dopamine Debate 28.02.2026 33m

This week we're doing something a little bit different on Movers & Shakers. We're joined in the pub by Dr Jonathan Sackner-Bernstein, a distinguised American cardiologist with a controversial idea: that Parkinson's might be caused by too much, rather than too little, dopamine. Sackner-Bernstein's ideas call into question the underlying assumptions of the condition and have been refuted by many of his colleagues. But the debate is worth having – not least as the opposition is eloquently represented by Dr Kit Wu – because it shows just how much we still don't understand about PD, dopamine, and the human brain.Movers & Shakers is brought to you in partnership with Cure Parkinson's.Presented by Rory Cellan-Jones, Gillian Lacey-Solymar, Mark Mardell, Paul Mayhew-Archer, Sir Nicholas Mostyn and Jeremy Paxman.Produced and edited by Nick Hilton for Podot.Sound mixing by Ewan Cameron.Music by Alex Stobbs. Hosted on Acast. See acast.com/privacy for more information.

Hallucinations 21.02.2026 34m

One of the strangest symptoms of Parkinson's is the sudden appearance of unexplained figures – whether that's a cat or a small child, a barking dog or a fully clad Venetian – in your environment. There hallucinations can be benign, but they can also be unsettling, and this week we're trying to find out what's causing them. Are they related to night terrors? Can they always be rationalised? And are there any potential treatment pathways for people struggling with hallucinatory visions? As ever, we're aided in our quest of understanding by a top expert.Movers & Shakers is brought to you in partnership with Cure Parkinson's.Presented by Rory Cellan-Jones, Gillian Lacey-Solymar, Mark Mardell, Paul Mayhew-Archer, Sir Nicholas Mostyn and Jeremy Paxman.Produced and edited by Nick Hilton for Podot.Sound mixing by Ewan Cameron.Music by Alex Stobbs. Hosted on Acast. See acast.com/privacy for more information.

Paraquat 14.02.2026 29m

This week we're returning to one of the most contentious subjects in Parkinson's world: what causes the condition? Research has increasingly focused on the role of pesticides – particularly one called Paraquat – which are routinely used in agriculture yet are severely toxic to humans. Could investigations into the role of Paraquat prove a connection to PD? And, if so, does that mean that we could, eventually, arrest the spread of the illness? To discuss this subject, the Movers and Shakers are joined in the pub by a filmmaker, Sarah Teale, who has been working with international experts on a new film that tries to unravel this link.Movers & Shakers is brought to you by Cure Parkinson's.Presented by Rory Cellan-Jones, Gillian Lacey-Solymar, Mark Mardell, Paul Mayhew-Archer, Sir Nicholas Mostyn and Jeremy Paxman.Produced and edited by Nick Hilton for Podot.Sound mixing by Ewan Cameron.Music by Alex Stobbs. Hosted on Acast. See acast.com/privacy for more information.

The 2026 Campaign 07.02.2026 31m

Last year was a landmark year for the Movers & Shakers team, as our Parky Charter project reached 100,000 petition signatories and generated a parliamentary debate. So how will we be following it up in 2026? To debate the possible campaigns we could embark on this year, the gang are joined by Mark 'Crippo' Cripps, our marketing guru, to try and come up with an impactful, yet achievable, proposition. As ever, you can send your thoughts and suggestions to us on social media or via email here.Movers & Shakers is brought to you by Cure Parkinson's.Presented by Rory Cellan-Jones, Gillian Lacey-Solymar, Mark Mardell, Paul Mayhew-Archer, Sir Nicholas Mostyn and Jeremy Paxman.Produced and edited by Nick Hilton for Podot.Sound mixing by Ewan Cameron.Music by Alex Stobbs. Hosted on Acast. See acast.com/privacy for more information.

Exercise: the evidence 31.01.2026 31m

If certain windsurfing former Judges are to be believed, there's nothing quite like a bout of vigorous exercise for easing the symptoms of Parkinson's. But does the medical evidence support this? Cramped into their booth in the Notting Hill pub, the Movers & Shakers pick over the verifiable scientific facts behind the assumption that exercise can alleviate PD symptoms. Is it possible to fairly analyse the impact of exercise? Could the effect be more psychological than physical? And might exercise, one day, be prescribed by your neurologist? We're discussing all this (and more) with top experts and the gang.Movers & Shakers is brought to you by Cure Parkinson's.Presented by Rory Cellan-Jones, Gillian Lacey-Solymar, Mark Mardell, Paul Mayhew-Archer, Sir Nicholas Mostyn and Jeremy Paxman.Produced and edited by Nick Hilton for Podot.Sound mixing by Ewan Cameron.Music by Alex Stobbs. Hosted on Acast. See acast.com/privacy for more information.

Freezing 24.01.2026 30m

Freezing is one of PD's most unusual symptoms. Whether it's a threshold, a zebra crossing or just getting out of bed, the sudden inability to move can strike at any moment. Why does it happen? And is there anything that can be done to combat this mysterious immobilisation? The Movers and Shakers – who have experienced very different types of freezing – squeeze into the Notting Hill pub (and hopefully don't freeze in place) with top experts on what's known as Freezing of Gait (FOG) or, here at M&S Towers, Freezing of Everything (FOE).Movers & Shakers is brought to you by Cure Parkinson's.Presented by Rory Cellan-Jones, Gillian Lacey-Solymar, Mark Mardell, Paul Mayhew-Archer, Sir Nicholas Mostyn and Jeremy Paxman.Produced and edited by Nick Hilton for Podot.Sound mixing by Ewan Cameron.Music by Alex Stobbs. Hosted on Acast. See acast.com/privacy for more information.

Parkinson's: the Sitcom 17.01.2026 28m

After our festive break, the Movers & Shakers are back in the Notting Hill pub with glad tidings for the new year. Gillian and the Judge have been sunning themselves (in Antigua and Australia, respectively), Rory has been hitting the Vegas strip, Mark has been battling with Turkish Airlines, and Paul has finally completed shooting of his new film. But Paul isn't the only Mayhew-Archer bringing life with Parkinson's to the screen. His son, Simon Mayhew-Archer, is the creator of Can You Keep a Secret? a new sitcom (loosely) based on his old man. Simon joins the gang, along with actor Mark Heap, who plays almost-Paul on the small screen, to discuss the family dynamics behind one of the BBC's best new comedies. Movers & Shakers is brought to you by Cure Parkinson's.Presented by Rory Cellan-Jones, Gillian Lacey-Solymar, Mark Mardell, Paul Mayhew-Archer, Sir Nicholas Mostyn and Jeremy Paxman.Produced and edited by Nick Hilton for Podot.Sound mixing by Ewan Cameron.Music by Alex Stobbs. Hosted on Acast. See acast.com/privacy for more information.

2025: The Year in Review 13.12.2025 26m

It's the end of another year – and what a year it's been! From the Big Sing on World Parkinson's Day through the Parky Petition campaign and getting our debate in Parliament, 2025 has been a stellar year for the Movers and Shakers and our community. For this final episode before we tootle off for Christmas, we've gathered at Chez Lacey-Solymar (minus Gillian herself, who was struck down by flu) to recap our year. What were the best moments of the year that's been? And which episodes of the podcast affected us most?Sponsored by Albion Chambers.Presented by Rory Cellan-Jones, Gillian Lacey-Solymar, Mark Mardell, Paul Mayhew-Archer, Sir Nicholas Mostyn and Jeremy Paxman.Produced and edited by Nick Hilton for Podot.Sound mixing by Ewan Cameron.Music by Alex Stobbs. Hosted on Acast. See acast.com/privacy for more information.

Parkinson's in Africa 06.12.2025 32m

From our little corner of the Notting Hill pub, it can be hard to see what life is like for people with Parkinson's across the rest of the UK – let alone around the world! Today, however, we're talking about Parkinson's care in Africa, a continent where levodopa access is limited and where stigmas around the condition still impact countless lives. We're joined by experts – both in the pub and down-the-line from the frontline of treatment – to try and understand the situation and how the global community might collaborate to alleviate some of the suffering of African Parkies.Sponsored by Albion Chambers.Presented by Rory Cellan-Jones, Gillian Lacey-Solymar, Mark Mardell, Paul Mayhew-Archer, Sir Nicholas Mostyn and Jeremy Paxman.Produced and edited by Nick Hilton for Podot.Sound mixing by Ewan Cameron.Music by Alex Stobbs. Hosted on Acast. See acast.com/privacy for more information.

The Mega Trial 29.11.2025 26m

How do you run clinical trials that maximise the efficiency for patients, clinicians and drugs developers? That's the challenge being addressed by world's largest ever clinical trial of Parkinson's medications. To discuss this new, and potentially extremely effective, way of runnings multiple trials simultaneously, the Movers & Shakers are joined at the pub by some of the core team from the project, who answer their questions and consider whether this represents the future of clinical trials.This special episode is sponsored by Cure Parkinson's.Presented by Rory Cellan-Jones, Gillian Lacey-Solymar, Mark Mardell, Paul Mayhew-Archer, Sir Nicholas Mostyn and Jeremy Paxman.Produced and edited by Nick Hilton for Podot.Sound mixing by Ewan Cameron.Music by Alex Stobbs. Hosted on Acast. See acast.com/privacy for more information.