A pinch of salt - A podcast by ERA

Episodes

• #78 B-cell therapy in IgA Nephropathy: worth the hype? with Vlado Perkovic 18.06.2026 36m

  For decades, treating IgA nephropathy meant looking thoughtful while saying "let's optimise supportive care and monitor closely." Not anymore. We've gone from one road to a full therapeutic roundabout, and nobody wants the wrong exit. Hugo Diniz welcomes Vlado Perkovic to navigate the new era: anti-APRIL and anti-BAFF agents, the VISIONARY and ORIGIN data, and the 2025 KDIGO framework. Are we finally switching off the disease at its source, or just admiring another elegant proteinuria curve? ...
• #77 Generative AI for the busy nephrologist: adapt or perish? with Wisit Cheungpasitporn 18.06.2026 48m

  Are we all about to be replaced by chatbots? Probably not — but is there a risk of Gen-AI acute tubular necrosis for those who don't adapt? Hugo Diniz is joined by Wisit Cheungpasitporn to demystify what generative AI can actually do, expose what it definitely can't (yet), and make it approachable for every working nephrologist. From automating those soul-crushing clinic notes to navigating the constant flow of new evidence, "vibe coding" your own tools, and the dark side of energy use and pa...
• #76 Late Breakers, LIVE from Glasgow, with Alberto Ortiz and Danilo Fliser 18.06.2026 31m

  This is “A pinch of salt” live from the 63rd ERA Congress! Recorded straight out of a packed Clyde Plenary Room: six trials, ninety minutes! Hugo Diniz, the new podcast host, brings you rapid-fire expert commentary with two titans of European nephrology, Alberto Ortiz and Danilo Fliser. On the menu — a brand-new CKD drug class (nurandociguat), what patients actually feel on semaglutide (FLOW sub-analysis), two IgA nephropathy therapies going long-term (atrasentan and iptacopan), anticoagulati...
• Trailer Late Breakers, LIVE from Glasgow, Generative AI for the busy nephrologist: adapt or perish? and B-cell therapy in IgA Nephropathy: worth the hype? 11.06.2026 1m
• #75 What is narrative-based medicine? with Amy Waterman 14.05.2026 39m

  In the 75th episode of A Pinch of Salt we'll be talking about narrative-based medicine, a topic that is not specific to nephrology, but it should be a core topic that is deeply involved in practicing patient-friendly clinical medicine. In medical schools we are taught extensively on how to get information from patients about their symptoms and signs, which will help us develop a differential diagnosis. But we don’t learn much about how to get information on the patient’s point of view, their ...
• #74 Inflammation and Aging in CKD – From Translational Basics to Clinical Practice, with Peter Stenvinkel 14.05.2026 25m

  In this episode we are joined by Peter Stenvinkel to discuss why Chronic Kidney Disease is increasingly recognized as a state of "fast-forward" aging. We dive into: The "Inflammaging" Factor- How chronic low-grade inflammation acts as a silent driver of vascular disease and frailty, the cellular Senescence: Exploring the gut-kidney axis and the "zombie cells" that stall recovery and clinical Intervention: Practical strategies for clinicians to monitor biological age and improve both qua...
• #73 Inhibition of Aldosterone Synthase and MRAs in Nephrology, with Maria Jose Soler Romeo 14.05.2026 17m

  In this episode Maria Jose Soler Romeo joins us to break down the shifting landscape of MRAs and Aldosterone Synthase Inhibition. We’ll cover the central role of aldosterone as a central culprit in inflammation and renal fibrosis, how the rise of non-steroidal MRAs is helping clinicians bypass traditional roadblocks like hyperkalemia and the future of slowing CKD progression through precision medicine.
• Trailer Inhibition of Aldosterone Synthase and MRAs in Nephrology, Inflammation and Aging in CKD – From Translational Basics to Clinical Practice, What is narrative-based medicine? 07.05.2026 2m
• #72 Liquid Biopsies and Other AI Goodies in Nephrology, with Valentin Goutaudier 16.04.2026 28m

  In this episode, we step into the future of transplantation with Valentin Goutaudier. Discover how precision diagnostics and artificial intelligence are coming together to enable more personalised, proactive care for renal transplant recipients and what this means for the future of medicine.
• #71 Obstacles for the Development of Peritoneal Dialysis – A Solution Toolbox, with Karlien François 16.04.2026 31m

  In this episode, Karlien François helps us dismantle the barriers to Peritoneal Dialysis. From structural challenges to patient perceptions, she introduces a practical “solution toolbox” designed to make PD a more accessible and flexible therapy for CKD patients worldwide. It’s time to turn obstacles into opportunities.
• #70 How to tackle PD complications? with Sana F. Khan 16.04.2026 27m

  In this episode, we explore the reality of clinical practice. It’s relatively easy to be a doctor when everything goes according to plan, but what happens when things get complicated? That’s where true experience comes into play. Join us as Sana F. Khan shares valuable insights on how to tackle Peritoneal Dialysis complications and build confidence in challenging situations.
• Trailer How to tackle PD complications?, Obstacles for the Development of Peritoneal Dialysis – A Solution Toolbox and Liquid Biopsies and Other AI Goodies in Nephrology 09.04.2026 1m
• #69 A Practical Guide on Frailty and Sarcopenia for CKD Patients, with Thomas Wilkinson 12.03.2026 25m

  In this very interesting episode with Thomas Wilkinson we talk about sarcopenia — its prevalence, the outcomes associated with it, the available tools for screening and assessment, the most effective interventions, and the importance of a multidisciplinary approach to care.
• #68 What’s New in Vascular Access? With Tamara Jemcov 12.03.2026 21m

  In this episode we’ll be talking to Tamara Jemcov, the current president of the Vascular Access Society, about novelties in the field of vascular access. If you haven’t checked out the programme from the last Vascular Access Congress which was held in 2025 Padova, you should take look. The field is really expanding and growing, and Tamara discussed the new approaches that were presented at the Congress. We also talked about the appropriate timing of vascular access construction, the immensely...
• #67 Extracorporeal Adsorption Techniques in ICU Patients – When to Say Yes, When to Suggest No? With Thomas Rimmele 12.03.2026 29m

  In this episode we will be talking with Thomas Rimmele, an expert in treating acute kidney injury in the ICU, about the role of the new extracorporeal adsorption techniques in ICU patients. We’ll be discussing who are the candidates, when to start treatment, how long should a single session last, how long should we continue doing it, which parameters to check to see if we are successful or not and much, much more. If you are unsure on how to use these techniques to benefit the sickest of pati...
• Trailer Extracorporeal adsorption techniques in ICU patients – when to say yes, when to suggest no?, What's new in vascular access?, A Practical Guide on Frailty and Sarcopenia for CKD Patients 05.03.2026 2m
• #66 Patient-reported outcomes in clinical practice, with Paul Cockwell 12.02.2026 33m

  In this episode of A pinch of salt we’ll be talking to Paul Cockwell about patient-reported outcomes in clinical practice. You may or may not be aware of these issues and their importance but one might argue, and we certainly would, that every doctor should be mindful of what their patients consider to be an important outcome and whether they are achieving it or not. Paul is a champion of this field, and he provided some very useful pointers on how a beginner in this field might get to know i...
• #65 About the GFR formulas – How to measure renal function in 2026? with Pierre Delanaye 12.02.2026 25m

  In this episode of A pinch of salt, we welcome Pierre Delanaye for a forward-looking discussion on how we should assess kidney function in 2026. Together, we explore the strengths and limits of today’s GFR equations (MDRD, CKD-EPI, cystatin C-based approaches), the promise of emerging biomarkers and AI-driven tools, and the crucial question of fairness and accuracy across diverse populations.
• #64 Evolution of Treatment Paradigms in ANCA Vasculitis, with David Jayne 12.02.2026 20m

  Join A pinch of salt, as we sit down with David Jayne to trace the rapid transformation of ANCA-associated vasculitis care. From the historic cyclophosphamide–glucocorticoid backbone to biologics like rituximab and newer targeted strategies such as complement inhibition (including avacopan), this episode unpacks how clinicians can balance efficacy, safety, and quality of life—while looking ahead to what may define the next decade of treatment.
• Trailer Evolution of Treatment Paradigms in ANCA Vasculitis, About the GFR formulas – How to measure renal function in 2026? and Patient-reported outcomes in clinical practice 05.02.2026 1m