Hope & Histamine: The Paediatric Allergy Podcast

Episodes

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  "May Contain" Food Allergens: Is Precautionary Labelling Putting Patients at Risk? | WAO ACT-UP! 2026 Consensus Explained 05.11.2026 57m

  Are “may contain” food allergy warnings protecting patients, or creating unnecessary confusion, anxiety and dietary restrictions? For millions of children and families living with food allergies, navigating supermarket shelves can be a daily challenge. Food packaging frequently carries statements such as “may contain nuts,” “may contain traces of milk,” or “made in a facility that handles allergens.” But what do these warnings actually mean? How reliable are they, and should every precautiona...
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  Newborn Bathing & Baby Skincare: Can They Prevent Eczema? Insights from the EAACI Global Survey 29.10.2026 51m

  Could a newborn’s first bath and early skincare routine influence their risk of developing eczema? In this episode of Hope & Histamine: The Paediatric Allergy Podcast, we explore an EAACI task force global survey of 319 international specialists, examining clinicians’ recommendations on neonatal bathing, baby skincare and the prevention of atopic dermatitis. We discuss when to give the first bath, how to cleanse delicate newborn skin, and recommendations on moisturisers. We also explore w...
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  Nasal Steroids in Children: Allergic Rhinitis, Adenoids & Safety—What Does the Evidence Say? 22.10.2026 57m

  Are nasal steroid sprays safe for children—and when do they really help? In this episode of Hope & Histamine: The Paediatric Allergy Podcast, we explore intranasal corticosteroids in children, from treating allergic rhinitis and hay fever to their potential role in enlarged adenoids and nasal obstruction. Drawing on a 2026 review in Pediatric Allergy and Immunology, we unpack the evidence behind these widely used treatments and address questions that matter to clinicians and families: • H...
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  Paediatric Asthma Update: What’s New in Childhood Asthma Management? 12.10.2026 24m

  What’s new in childhood asthma care—and what does it mean for everyday practice? In this episode of Hope & Histamine: The Paediatric Allergy Podcast, we explore recent advances in paediatric asthma management, from inhaled treatments and personalised care to the evolving role of biologics in severe asthma. We discuss key questions around asthma diagnosis, inhaler technique, treatment adherence and preventing exacerbations, alongside emerging approaches to help children achieve better asth...
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  Omalizumab vs Oral Immunotherapy for Multiple Food Allergies: OUtMATCH Trial Explained 03.10.2026 43m

  How does omalizumab compare with oral immunotherapy for treating multiple food allergies? In this episode of Hope & Histamine: The Paediatric Allergy Podcast, we explore OUtMATCH Stage 2, comparing omalizumab (Xolair) with omalizumab-facilitated multi-allergen oral immunotherapy (OIT). We unpack the findings on treatment success, allergic reactions, side effects and treatment discontinuation—and explain why tolerability matters when interpreting the results. What do these findings mean fo...
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  Eggs and Peanuts in Pregnancy: Why More Didn’t Reduce Infant Allergy Risk 22.09.2026 52m

  Can eating more eggs and peanuts during pregnancy and breastfeeding reduce a baby’s risk of developing food allergy? In this episode of Hope & Histamine: The Paediatric Allergy Podcast, we examine the PrEggNut trial, a large randomised study involving more than 2,100 pregnant women whose babies had a strong family history of allergic disease. Researchers compared a maternal diet rich in eggs and peanuts with a standard-intake diet from pregnancy until four months after birth. Despite grea...
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  Kounis Syndrome Explained: When a Severe Allergic Reaction Triggers Acute Coronary Syndrome 13.09.2026 52m

  What happens when a severe allergic reaction affects not only the skin and airways but also the coronary arteries? In this episode of Hope & Histamine: The Paediatric Allergy Podcast, we explore Kounis syndrome—an acute coronary syndrome triggered by an allergic or hypersensitivity reaction. We discuss how mast-cell activation and inflammatory mediators can cause coronary artery spasm, plaque disruption or stent thrombosis, resulting in symptoms that may resemble a heart attack alongside ...
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  Rethinking the Blue Inhaler: Budesonide–Formoterol vs Salbutamol in Children with Mild Asthma | The CARE Trial 07.09.2026 39m

  Is it time to rethink the traditional blue reliever inhaler for children with mild asthma? In this episode of Hope & Histamine: The Paediatric Allergy Podcast, we examine the landmark 2025 CARE trial published in The Lancet. This 52-week randomised controlled trial compared budesonide–formoterol with salbutamol as reliever therapy in children with mild asthma. We explore whether an anti-inflammatory reliever inhaler can provide better protection than salbutamol alone, examining the trial’...
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  The Peanut Patch Revolution: Is Epicutaneous Immunotherapy the Future of Peanut Allergy Treatment in Children? 28.08.2026 23m

  Could a simple skin patch transform the treatment of peanut allergy in young children? In this episode of Hope & Histamine: The Paediatric Allergy Podcast, we explore the latest evidence on epicutaneous immunotherapy (EPIT)—also known as the peanut patch—for toddlers and children with peanut allergy. Drawing on findings from the EPITOPE and EPOPEX studies, we examine how peanut patch therapy works, its long-term effectiveness and safety, and whether it can increase the amount of peanut a ...
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  Dupilumab in Children: A Game-Changer for Eczema, Asthma and Atopic Disease 19.08.2026 33m

  Dupilumab has transformed the treatment of several type 2 inflammatory conditions—but how does it work, which children may benefit, and what should clinicians and families know before starting treatment? In this episode of Hope & Histamine: The Paediatric Allergy Podcast, we explore the expanding role of dupilumab in paediatrics, including its use in atopic dermatitis (eczema), severe asthma and eosinophilic oesophagitis. We discuss how blocking interleukin-4 and interleukin-13 signalling...
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  Pediatric Hereditary Angioedema: Diagnosis, Treatment & Long-Term Management 08.08.2026 22m

  Hereditary angioedema (HAE) is a rare but potentially life-threatening genetic disorder that often presents during childhood, yet diagnosis is frequently delayed for many years. Early recognition and timely treatment can dramatically improve quality of life and reduce the risk of serious complications, including airway obstruction. In this episode of Hope & Histamine: The Paediatric Allergy Podcast, we explore the latest evidence and practical approaches to diagnosing and managing paediat...
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  Allergy and Eustachian Tube Dysfunction: Causes, Symptoms, Diagnosis & Treatment 01.08.2026 30m

  Why do your ears feel blocked during allergy season? Can hay fever really affect your hearing? What causes that frustrating sensation of ear fullness, popping, crackling or pressure that just won’t go away? In this episode of Hope & Histamine: The Paediatric Allergy Podcast, we explore the important relationship between allergic disease and Eustachian Tube Dysfunction (ETD)—a common but often misunderstood condition affecting both children and adults. Join us as we discuss: What the Eusta...
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  Orofacial Granulomatosis (OFG): Symptoms, Diagnosis, Causes & Modern Treatment 24.07.2026 57m

  Orofacial Granulomatosis (OFG) is a rare but often overlooked inflammatory condition that can present with persistent lip swelling, oral ulcers, gum changes, and facial swelling. Because its symptoms overlap with many other conditions, diagnosis is frequently delayed, leaving patients and families searching for answers. In this episode of Hope & Histamine: The Paediatric Allergy Podcast, we take a deep dive into the science and clinical management of Orofacial Granulomatosis. We discuss w...
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  Idiopathic Anaphylaxis Explained: Causes, Diagnosis & Treatment 13.07.2026 53m

  What happens when someone experiences anaphylaxis, but no trigger can be identified? In this episode of Hope & Histamine: The Paediatric Allergy Podcast, we explore idiopathic anaphylaxis—a diagnosis that can be both frightening for patients and challenging for clinicians. Join us as we discuss the latest understanding of idiopathic anaphylaxis, including how it is diagnosed, important conditions that can mimic anaphylaxis, and the investigations needed to exclude identifiable causes such...
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  Preventing and Treating Peanut Allergy in Children: From Early Introduction to Immunotherapy 04.07.2026 38m

  Peanut allergy has become one of the most important and widely discussed topics in paediatric allergy. In this episode of Hope & Histamine: The Paediatric Allergy Podcast, we explore the prevention and treatment of peanut allergy in children, from the landmark evidence supporting early peanut introduction to the evolving role of oral immunotherapy. We discuss why peanut allergy develops, which children are at higher risk, and how early dietary exposure may help reduce the chance of allerg...
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  Eosinophilic Oesophagitis (EoE) Explained: Pathophysiology, Diagnosis, and Modern Treatment Strategies 24.06.2026 1h 7m

  In this episode of Hope & Histamine: The Paediatric Allergy Podcast, we explore Eosinophilic Oesophagitis, or EoE— an increasingly recognised allergic inflammatory condition of the oesophagus that can affect feeding, swallowing, growth, and quality of life in children and young people. We break down the pathophysiology of EoE, including the role of food allergens, type 2 inflammation, eosinophils, epithelial barrier dysfunction, and immune signalling pathways. The episode also covers how ...
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  Bee and Wasp Sting Allergy in Children: Diagnosis, Risk Assessment and Management of Hymenoptera Venom Allergy 14.06.2026 1h 1m

  In this episode of Hope & Histamine: The Paediatric Allergy Podcast, we explore the diagnosis and management of Hymenoptera venom allergy in children, including allergic reactions to bee, wasp and other insect stings. We discuss how to distinguish between normal local reactions, large local reactions and systemic allergic reactions, and when a child should be referred for specialist allergy assessment. The episode covers key aspects of diagnosis, including clinical history, venom-specific...
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  Food Allergy Anxiety: The Hidden Impact on Children, Parents and Everyday Life 06.06.2026 42m

  Food allergies are often seen as a medical condition centred around avoidance, emergency plans and adrenaline auto-injectors — but the impact goes far beyond the plate. In this episode of Hope & Histamine: The Paediatric Allergy Podcast, we explore how food allergies affect children’s emotional wellbeing, family life, school experiences, social confidence and overall quality of life. We discuss the anxiety, fear and daily uncertainty that many children and parents live with, from checking...
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  Ibuprofen Allergy or NSAID Hypersensitivity in Children? Diagnosis and Management Guide 29.05.2026 52m

  NSAID hypersensitivity in children can be challenging to recognise, diagnose, and manage safely. In this episode of Hope & Histamine: The Paediatric Allergy Podcast, we explore paediatric NSAID hypersensitivity, including reactions to commonly used medicines such as ibuprofen and other non-steroidal anti-inflammatory drugs. We discuss the different types of NSAID reactions, how to distinguish true hypersensitivity from other adverse effects, and the importance of a careful clinical histor...
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  Penicillin Allergy in Children: Myths, Diagnosis, Delabelling, and Safe Antibiotic Choices 22.05.2026 23m

  Penicillin allergy is one of the most commonly reported drug allergies in children — but many children labelled as “penicillin allergic” are not truly allergic. In this episode, we explore why penicillin allergy labels matter, how they can affect antibiotic choices, and why accurate assessment is so important for safer, better care. We discuss the difference between true allergic reactions and common childhood rashes, the key features clinicians look for in the history, and when referral or a...